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[190764_at] serine/threonine kinase

Description T05C12.1 /REP_DB=WormBase Gene ID /WP=CE02312 /TR=Q22223 /GB=CAA91303.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster 6grp_total > 88      4grp_total > 39      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 32
1 2 3 4 range
A 34.9
(2.7)
A 		9.7
(-3)
A 		31.8
(2)
A 		36
(3)
A 		26
B 31.6
(3)
A 		12.6
(-1.2)
A 		31.7
(3)
A 		4.1
(-3)
A 		28
C 20.9
(0.1)
A 		35.6
(3)
A 		5.7
(-3)
A 		29.6
(1.8)
M 		30
avr 29.1
(3) 		19.3
(-3) 		23.1
(-0.7) 		23.2
(-0.6) 		10

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 231
1 2 3 4 5 6 range
A 43.9
(-1.5)
A 		19.8
(-3)
A 		23.5
(-2.8)
A 		38.9
(-1.8)
A 		117.1
(3)
P 		103.1
(2.1)
P 		97
B 5.5
(-3)
A 		16
(-2.6)
A 		17.1
(-2.6)
A 		21.2
(-2.5)
A 		86.4
(-0.2)
P 		181.3
(3)
P 		176
C 5.6
(-3)
A 		34.2
(-2.3)
A 		17.7
(-2.7)
A 		41.4
(-2.1)
A 		57.2
(-1.7)
A 		236.8
(3)
P 		231
avr 18.3
(-3) 		23.3
(-2.8) 		19.4
(-3) 		33.8
(-2.4) 		86.9
(-0.4) 		173.7
(3) 		155
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 12
1 2 3 4 range
A 12.7
(3)
A 		2.1
(-3)
A 		8.3
(0.5)
A 		5.3
(-1.2)
A 		11
B 10.1
(3)
A 		3.1
(-1.6)
A 		7.3
(1.2)
A 		0.9
(-3)
A 		9
C 6.9
(0.6)
A 		10.2
(3)
A 		2
(-3)
A 		5
(-0.8)
M 		8
avr 9.9
(3) 		5.1
(-1.6) 		5.9
(-0.9) 		3.7
(-3) 		6

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 77
1 2 3 4 5 6 range
A 8.1
(-2.4)
A 		7
(-2.6)
A 		5.1
(-3)
A 		9.9
(-2)
A 		35.3
(3)
P 		25.1
(1)
P 		30
B 1.9
(-3)
A 		5.3
(-2.7)
A 		4.2
(-2.8)
A 		5.6
(-2.7)
A 		35.1
(0)
P 		67.6
(3)
P 		66
C 2.1
(-3)
A 		10.4
(-2.4)
A 		4.5
(-2.8)
A 		8.3
(-2.5)
A 		18.5
(-1.7)
A 		79.3
(3)
P 		77
avr 4
(-3) 		7.6
(-2.6) 		4.6
(-2.9) 		7.9
(-2.6) 		29.6
(-0.1) 		57.3
(3) 		53
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190764_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.2964
Sequence Type Exemplar sequence
Representative Public ID T05C12.1 NCBI
Target Description T05C12.1 /REP_DB=WormBase Gene ID /WP=CE02312 /TR=Q22223 /GB=CAA91303.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_063314(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_063314 NCBI Caenorhabditis elegans T05C12.1 (T05C12.1) mRNA, complete cds. 11/11 None
SNAP00000002109 ENSEMBL cdna:SNAP chromosome:CEL140:II:8173626:8174748:1 11/11 None
GENEFINDER00000002118 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:8173821:8174733:1 11/11 None
T05C12.1 ENSEMBL cdna:known chromosome:CEL140:II:8173626:8174748:1 gene:T05C12.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:8173622-8174745(+) 100.0 100.0
Public Domain and Genome References
Gene Title serine/threonine kinase
Ensembl T05C12.1
Entrez Gene 188121 Entrez gene
SwissProt Q22223 EMBL-EBI
WormBase CE02312 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA91303 Hypothetical protein T05C12.1 [Caenorhabditis elegans] ref|NP_495715.1| T05C12.1 [Caenorhabditis elegans] 0.0
blast CAA91303 Hypothetical protein T05C12.1 [Caenorhabditis elegans] ref|NP_495715.1| T05C12.1 [Caenorhabditis elegans] 1.0E-160
blast CAE57592 Hypothetical protein CBG00573 [Caenorhabditis briggsae] 1.0E-147
blast CAE57592 Hypothetical protein CBG00573 [Caenorhabditis briggsae] 1.0E-128
blast CAB05829 Hypothetical protein W06F12.3 [Caenorhabditis elegans] ref|NP_499835.1| W06F12.3 [Caenorhabditis elegans] 2.0E-71
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 4.3E-23
Pfam IPR000719 EMBL-EBI Protein kinase 1.2E-20
Sequence
Target Sequence 
>C. ELEGANS:190764_AT
gatttcaatcttatcttctgttcgaattggcattcaaatcattgaagctctatctttgct
tcattcaaaaggatggcttcatcgtgatttgaaaccaactaactgttgcctgggacttga
tgaaaaacggaagacggtttatctcgttgattttggaatgtcccgaaagtttcgtaatga
taatggaagtctccgtgaaagtagaacatattgtggattcagaggaactactcgttattg
ttcgtatagaatgcatgaccgccgggagcagggaccagttgatgatttatggtgtcttta
ttattcgttgggtgaattgattgaaggatgtttgccatggagagatatcgaatcagctga
tgagatggctcatgttaagaagattttgaaacatgaggacatatttcattcaatgccatc
aaaattcgcaagttttggaagaaaccttcgtcgtcttcgtccagccaacactccggatta
taccaaattccagaatattttggcctactgtgtgaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GATTTCAATCTTATCTTCTGTTCGA 128 429 426 Antisense
TATCTTCTGTTCGAATTGGCATTCA 211 659 437 Antisense
AAAGGATGGCTTCATCGTGATTTGA 444 121 493 Antisense
AACTAACTGTTGCCTGGGACTTGAT 59 139 522 Antisense
ACGGAAGACGGTTTATCTCGTTGAT 67 95 552 Antisense
GAGGAACTACTCGTTATTGTTCGTA 322 405 647 Antisense
TATAGAATGCATGACCGCCGGGAGC 172 659 670 Antisense
GCCGGGAGCAGGGACCAGTTGATGA 76 285 686 Antisense
ATGGTGTCTTTATTATTCGTTGGGT 503 49 714 Antisense
TCCAGCCAACACTCCGGATTATACC 538 587 885 Antisense
AGAATATTTTGGCCTACTGTGTGAA 426 75 917 Antisense
Sequence Source Affymetrix Proprietary Database