[Home] | [Total List]

[190758_at] Sodium/Proton antiporter

Description B0395.1 /REP_DB=WormBase Gene ID /WP=CE17339 /TR=O01995 /GB=CAA92219.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=Sodium-Proton antiporter
Cluster 6grp_high1_10_10 > 0      6grp_total > 90      4grp_total > 59      6grp_cgc > 95      6grp_cgc_sub > 04      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 112
1 2 3 4 range
A 102.8
(0.3)
A 		134
(3)
P 		109.5
(0.9)
A 		65.5
(-3)
A 		69
B 98.2
(0.5)
A 		93.7
(0.1)
A 		129
(3)
M 		56.2
(-3)
A 		73
C 88.9
(1)
A 		101.4
(1.7)
A 		122.5
(3)
P 		21.7
(-3)
A 		101
avr 96.6
(1) 		109.7
(2.1) 		120.3
(3) 		47.8
(-3) 		73

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 162
1 2 3 4 5 6 range
A 224.3
(3)
P 		85.8
(-3)
A 		156.6
(0.1)
P 		189.5
(1.5)
P 		116.2
(-1.7)
P 		118.9
(-1.6)
P 		139
B 153.3
(-0.5)
P 		148.6
(-1.2)
P 		142.7
(-2)
P 		179.7
(3)
P 		167.8
(1.4)
P 		134.9
(-3)
P 		45
C 94.6
(-1.6)
A 		141.8
(0.3)
P 		62.1
(-3)
A 		206
(3)
P 		108.3
(-1.1)
A 		131.1
(-0.1)
P 		144
avr 157.4
(0.1) 		125.4
(-2.6) 		120.5
(-3) 		191.7
(3) 		130.8
(-2.1) 		128.3
(-2.3) 		71
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 39
1 2 3 4 range
A 37.4
(3)
A 		29.1
(1.2)
P 		28.6
(1.1)
A 		9.6
(-3)
A 		28
B 31.3
(3)
A 		23.1
(0.5)
A 		29.9
(2.6)
M 		12
(-3)
A 		19
C 29.4
(1)
A 		29.1
(0.9)
A 		42.7
(3)
P 		3.7
(-3)
A 		39
avr 32.7
(2.8) 		27.1
(1.4) 		33.7
(3) 		8.4
(-3) 		25

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 52
1 2 3 4 5 6 range
A 41.4
(0.9)
P 		30.5
(-2.5)
A 		34.1
(-1.4)
P 		48.1
(3)
P 		35.1
(-1.1)
P 		28.9
(-3)
P 		19
B 53.3
(0.3)
P 		49.4
(-0.4)
P 		34.7
(-3)
P 		47.6
(-0.7)
P 		68.2
(3)
P 		50.3
(-0.2)
P 		34
C 35.1
(1.1)
A 		43.3
(2.9)
P 		15.8
(-3)
A 		41.4
(2.5)
P 		35.1
(1.1)
A 		43.9
(3)
P 		28
avr 43.3
(2.1) 		41.1
(1.3) 		28.2
(-3) 		45.7
(2.9) 		46.1
(3) 		41
(1.3) 		18
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190758_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.17730
Sequence Type Exemplar sequence
Representative Public ID B0395.1 NCBI
Target Description B0395.1 /REP_DB=WormBase Gene ID /WP=CE17339 /TR=O01995 /GB=CAA92219.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=Sodium-Proton antiporter
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_078221(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_078221 NCBI Caenorhabditis elegans Na/H eXchanger family member (nhx-1) (nhx-1) mRNA, complete cds. 11/11 None
SNAP00000033249 ENSEMBL cdna:SNAP chromosome:CEL140:X:16019614:16021595:1 10/11 None
GENEFINDER00000033253 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:16019614:16021595:1 11/11 None
B0395.1 ENSEMBL cdna:known chromosome:CEL140:X:16018601:16021657:1 gene:B0395.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:16018600-16021595(+) 100.0 100.0
Public Domain and Genome References
Gene Title Sodium/Proton antiporter
Gene Symbol nhx-1
Ensembl B0395.1
Entrez Gene 181680 Entrez gene
SwissProt O01995 EMBL-EBI
WormBase CE30842 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6814 sodium ion transport inferred from electronic annotation QuickGO AmiGO
6885 regulation of pH inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16021 integral to membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
15299 solute:hydrogen antiporter activity inferred from electronic annotation QuickGO AmiGO
15385 sodium:hydrogen antiporter activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA92219 Hypothetical protein B0395.1 [Caenorhabditis elegans] emb|CAB09132.2| Hypothetical protein B0395.1 [Caenorhabditis elegans] ref|NP_510622.2| Na/H eXchanger family member (nhx-1) [Caenorhabditis elegans] 0.0
blast AAM18101 putative Na-H exchanger isoform 1 [Caenorhabditis elegans] 0.0
blast CAE70003 Hypothetical protein CBG16410 [Caenorhabditis briggsae] 0.0
blast CAA92219 Hypothetical protein B0395.1 [Caenorhabditis elegans] emb|CAB09132.2| Hypothetical protein B0395.1 [Caenorhabditis elegans] ref|NP_510622.2| Na/H eXchanger family member (nhx-1) [Caenorhabditis elegans] 1.0E-171
blast AAM18101 putative Na-H exchanger isoform 1 [Caenorhabditis elegans] 1.0E-171
blast CAE70003 Hypothetical protein CBG16410 [Caenorhabditis briggsae] 1.0E-157
blast CAA92219 Hypothetical protein B0395.1 [Caenorhabditis elegans] emb|CAB09132.2| Hypothetical protein B0395.1 [Caenorhabditis elegans] ref|NP_510622.2| Na/H eXchanger family member (nhx-1) [Caenorhabditis elegans] 1.0E-138
Protein Domains
Database ID Description E-Value
Pfam IPR006153 EMBL-EBI Sodium/hydrogen exchanger 1.8E-117
Pfam IPR006153 EMBL-EBI Sodium/hydrogen exchanger 7.3E-65
Pfam IPR006153 EMBL-EBI Sodium/hydrogen exchanger 9.8E-66
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_510622.2 10 7-29,39-56,68-90,100-122,176-198,225-247,259-281,291-313,333-352,362-384
B0395.1 10 7-29,39-56,68-90,100-122,176-198,225-247,259-281,291-313,333-352,362-384
SNAP00000033249 6 21-43,70-92,104-126,136-158,177-199,204-226
GENEFINDER00000033253 6 21-43,70-92,104-126,136-158,178-197,207-229
Sequence
Target Sequence 
>C. ELEGANS:190758_AT
atcttcgtattcttgggattttccatattttcaaaggatcataaatgggactttggtttt
gcaattgtcactgttatcacttgctttgctgccagattcctcgttgtgttcacattaaca
tgggtggcaaacaagtggagaatgcaaaaaatttcactgcgagatcagacaatcatggcg
tttggtggacttcgaggtgcaatttgttttggattagtgttaactatcgacggagaagta
gtcccggccaagccgatcatgatatccaccacattgatagtaatagtattcactgtattt
attcaaggaacaatgataaagccactggtatcgtttttaaatgtgaaaattgacaatgct
tatgacaagtctttattccaaagttgtattgaacattcattcgaagacacaatgtgcggt
gttgaagcaataattggagctcatgggcagtactactggaaaaacaaagtcgacaaatgg
aatgctcaattcttggagccagctctcacccgacaggatatgaatcgaggcaggcggctc
ttgaaaaagttgactgacatgacaaccgacgagcaacgggaagctctgttacaggaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATCTTCGTATTCTTGGGATTTTCCA 559 31 820 Antisense
TTGTCACTGTTATCACTTGCTTTGC 572 705 884 Antisense
CAGATTCCTCGTTGTGTTCACATTA 220 207 912 Antisense
TCATGGCGTTTGGTGGACTTCGAGG 581 621 992 Antisense
GACGGAGAAGTAGTCCCGGCCAAGC 667 375 1048 Antisense
GGCCAAGCCGATCATGATATCCACC 60 543 1065 Antisense
TGGAGCTCATGGGCAGTACTACTGG 177 547 1254 Antisense
TCAATTCTTGGAGCCAGCTCTCACC 398 633 1305 Antisense
TGAATCGAGGCAGGCGGCTCTTGAA 24 577 1340 Antisense
GACTGACATGACAACCGACGAGCAA 540 375 1371 Antisense
GCAACGGGAAGCTCTGTTACAGGAA 561 317 1392 Antisense
Sequence Source Affymetrix Proprietary Database