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[190745_at] serine/threonine kinase

Description C05C12.1 /REP_DB=WormBase Gene ID /WP=CE02965 /TR=Q17651 /GB=CAA92725.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster 6grp_total > 87      4grp_total > 43      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 38
1 2 3 4 range
A 1.5
(-3)
A 		39.1
(3)
A 		3
(-2.8)
A 		13.1
(-1.1)
A 		38
B 5.1
(-2.9)
A 		24.6
(3)
A 		14.3
(-0.1)
A 		4.8
(-3)
A 		20
C 6.3
(2.4)
A 		2.6
(-3)
A 		4.5
(-0.2)
A 		6.7
(3)
A 		4
avr 4.3
(-3) 		22.1
(3) 		7.3
(-2) 		8.2
(-1.7) 		18

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 98
1 2 3 4 5 6 range
A 7.6
(-2.4)
A 		6.8
(-2.5)
A 		11.6
(-2)
A 		2.4
(-3)
A 		26.5
(-0.4)
A 		57.2
(3)
P 		55
B 2.8
(-3)
A 		7.8
(-2.6)
A 		9.9
(-2.5)
A 		2.7
(-3)
A 		40.6
(-0.3)
P 		86.7
(3)
P 		84
C 3.4
(-3)
A 		18
(-2.1)
A 		10
(-2.6)
A 		30.1
(-1.3)
A 		41.9
(-0.6)
A 		99.9
(3)
P 		97
avr 4.6
(-3) 		10.9
(-2.5) 		10.5
(-2.5) 		11.7
(-2.4) 		36.3
(-0.5) 		81.3
(3) 		77
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 8
1 2 3 4 range
A 0.5
(-3)
A 		8.5
(3)
A 		0.8
(-2.8)
A 		1.9
(-2)
A 		8
B 1.6
(-2.3)
A 		6.1
(3)
A 		3.3
(-0.3)
A 		1
(-3)
A 		5
C 2.1
(3)
A 		0.7
(-3)
A 		1.6
(0.9)
A 		1.1
(-1.3)
A 		1
avr 1.4
(-2.8) 		5.1
(3) 		1.9
(-2.1) 		1.3
(-3) 		4

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 33
1 2 3 4 5 6 range
A 1.4
(-2.6)
A 		2.4
(-2.2)
A 		2.5
(-2.1)
A 		0.6
(-3)
A 		8
(0.3)
A 		13.9
(3)
P 		13
B 1
(-2.9)
A 		2.6
(-2.6)
A 		2.4
(-2.7)
A 		0.7
(-3)
A 		16.5
(0)
P 		32.3
(3)
P 		32
C 1.3
(-3)
A 		5.5
(-2.2)
A 		2.5
(-2.8)
A 		6.1
(-2.1)
A 		13.6
(-0.7)
A 		33.4
(3)
P 		32
avr 1.2
(-3) 		3.5
(-2.5) 		2.5
(-2.7) 		2.5
(-2.7) 		12.7
(-0.3) 		26.5
(3) 		25
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190745_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.10150
Sequence Type Exemplar sequence
Representative Public ID C05C12.1 NCBI
Target Description C05C12.1 /REP_DB=WormBase Gene ID /WP=CE02965 /TR=Q17651 /GB=CAA92725.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069711(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069711 NCBI Caenorhabditis elegans C05C12.1 (C05C12.1) mRNA, complete cds. 11/11 None
SNAP00000019477 ENSEMBL cdna:SNAP chromosome:CEL140:IV:11253968:11255674:1 11/11 None
GENEFINDER00000019484 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:11253968:11255674:1 11/11 None
C05C12.1 ENSEMBL cdna:known chromosome:CEL140:IV:11253956:11255674:1 gene:C05C12.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:11253973-11255680(+) 100.0 100.0
Public Domain and Genome References
Gene Title serine/threonine kinase
Ensembl C05C12.1
Entrez Gene 178032 Entrez gene
SwissProt Q17651 EMBL-EBI
WormBase CE02965 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA92725 Hypothetical protein C05C12.1 [Caenorhabditis elegans] ref|NP_502112.1| C05C12.1 [Caenorhabditis elegans] 0.0
blast NP_501151 D2024.1 [Caenorhabditis elegans] gb|AAA82292.1| Hypothetical protein D2024.1 [Caenorhabditis elegans] 1.0E-167
blast CAE67306 Hypothetical protein CBG12760 [Caenorhabditis briggsae] 1.0E-103
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 4.8E-9
Pfam IPR000719 EMBL-EBI Protein kinase 4.0E-6
Sequence
Target Sequence 
>C. ELEGANS:190745_AT
aagctcatgctatggccgatttgggaagaggtgatgatttgtggtccctcatgtatatga
ttgctgagctcgtgaaaccattgccatgggagatactcgaagcgaaaatgttggaaaaca
cgaaactcaagagtaagctcaaggatcatttcggcatggatggatttggaaaaattgaaa
ccatgctccatgcctgcactttcaactcatttccaaactatgaaatgatataccttgcat
tcaaagaagtgttcaacaaaagtggggtttcttggctagatccttatgattgggagggaa
agaacatgccgtcttacaaacgatggagacagcatgccgaaaaacagcgtccattgttcg
cttgggaacagcctgacgtcggctcttacttccgaaaggatccatttacaacggttcaaa
atgcaaatgtaacggggaagacgacgaaaaagaagaagcatgggaaggaaacaactgatg
agacgactgtggagacttgcgaggaaatcaacggatctgtcaagaagccaca

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAGCTCATGCTATGGCCGATTTGGG 501 149 659 Antisense
GATTTGTGGTCCCTCATGTATATGA 270 427 694 Antisense
CTGAGCTCGTGAAACCATTGCCATG 109 239 722 Antisense
GGATCATTTCGGCATGGATGGATTT 75 513 801 Antisense
TGGGGTTTCTTGGCTAGATCCTTAT 533 553 921 Antisense
ACAGCATGCCGAAAAACAGCGTCCA 673 107 987 Antisense
AACAGCGTCCATTGTTCGCTTGGGA 30 135 1001 Antisense
GTCGGCTCTTACTTCCGAAAGGATC 501 469 1036 Antisense
GAAAGGATCCATTTACAACGGTTCA 534 359 1052 Antisense
GAGACGACTGTGGAGACTTGCGAGG 38 395 1138 Antisense
TCAACGGATCTGTCAAGAAGCCACA 315 631 1166 Antisense
Sequence Source Affymetrix Proprietary Database