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[190739_at] Tyrosine-protein kinase

Description B0252.1 /REP_DB=WormBase Gene ID /WP=CE02417 /TR=Q10915 /GB=AAC46755.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation /DEF=Tyrosine-protein kinase
Cluster 6grp_total > 52      4grp_total > 10      6grp_total_sub > Hat      6grp_rule_based > S3      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 275
1 2 3 4 range
A 73.5
(-2.3)
A 		43.3
(-3)
A 		54.2
(-2.7)
A 		301.3
(3)
P 		258
B 26.4
(-3)
A 		112.4
(0.6)
A 		80.1
(-0.8)
A 		171.2
(3)
P 		145
C 127.2
(-1.3)
A 		94.6
(-3)
A 		102.8
(-2.6)
P 		210.7
(3)
P 		116
avr 75.7
(-3) 		83.4
(-2.7) 		79
(-2.9) 		227.7
(3) 		152

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 308
1 2 3 4 5 6 range
A 18.5
(-3)
A 		124.3
(0.5)
P 		201
(3)
P 		106.4
(-0.1)
P 		91
(-0.6)
P 		66.8
(-1.4)
A 		183
B 79.2
(-2.7)
A 		194.1
(-0.1)
P 		326
(3)
P 		132.2
(-1.5)
P 		67.8
(-3)
P 		107.3
(-2.1)
P 		258
C 62.5
(-3)
A 		267.2
(3)
P 		214.6
(1.5)
P 		105.3
(-1.7)
P 		71
(-2.8)
A 		73.8
(-2.7)
P 		205
avr 53.4
(-3) 		195.2
(1.4) 		247.2
(3) 		114.6
(-1.1) 		76.6
(-2.3) 		82.6
(-2.1) 		194
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 36
1 2 3 4 range
A 26.8
(0)
A 		9.4
(-3)
A 		14.2
(-2.2)
A 		44.1
(3)
P 		35
B 8.4
(-3)
A 		27.8
(1.1)
A 		18.6
(-0.8)
A 		36.5
(3)
P 		28
C 42.1
(3)
A 		27.2
(-3)
A 		35.8
(0.5)
P 		35.5
(0.3)
P 		15
avr 25.8
(-1.5) 		21.5
(-3) 		22.9
(-2.5) 		38.7
(3) 		17

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 78
1 2 3 4 5 6 range
A 3.4
(-3)
A 		44.2
(3)
P 		43.8
(2.9)
P 		27
(0.5)
P 		27.5
(0.5)
P 		16.3
(-1.1)
A 		41
B 27.6
(-3)
A 		64.6
(1.3)
P 		79.2
(3)
P 		35
(-2.1)
P 		27.5
(-3)
P 		40
(-1.5)
P 		52
C 23.2
(-2.8)
A 		81.5
(3)
P 		54.6
(0.3)
P 		21.2
(-3)
P 		23
(-2.8)
A 		24.7
(-2.7)
P 		60
avr 18.1
(-3) 		63.4
(3) 		59.2
(2.4) 		27.7
(-1.7) 		26
(-2) 		27
(-1.8) 		45
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190739_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.4135
Sequence Type Exemplar sequence
Representative Public ID B0252.1 NCBI
Target Description B0252.1 /REP_DB=WormBase Gene ID /WP=CE02417 /TR=Q10915 /GB=AAC46755.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation /DEF=Tyrosine-protein kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_063018(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_063018 NCBI Caenorhabditis elegans B0252.1 (B0252.1) mRNA, complete cds. 11/11 None
SNAP00000013958 ENSEMBL cdna:SNAP chromosome:CEL140:II:6919702:6923502:1 11/11 None
GENEFINDER00000013963 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:6919702:6923502:1 11/11 None
B0252.1 ENSEMBL cdna:known chromosome:CEL140:II:6919660:6923629:1 gene:B0252.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:6919697-6923498(+) 100.0 100.0
Public Domain and Genome References
Gene Title Tyrosine-protein kinase
Ensembl B0252.1
Entrez Gene 174133 Entrez gene
SwissProt Q10915 EMBL-EBI
WormBase CE02417 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAC46755 Hypothetical protein B0252.1 [Caenorhabditis elegans] ref|NP_495419.1| B0252.1 [Caenorhabditis elegans] 0.0
blast CAE65996 Hypothetical protein CBG11187 [Caenorhabditis briggsae] 0.0
blast CAE74901 Hypothetical protein CBG22767 [Caenorhabditis briggsae] 4.0E-39
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 1.8E-37
Pfam IPR000719 EMBL-EBI Protein kinase 1.8E-37
Pfam IPR000719 EMBL-EBI Protein kinase 1.8E-37
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_495419.1 1 361-380
B0252.1 1 361-380
SNAP00000013958 1 351-370
GENEFINDER00000013963 1 443-462
Sequence
Target Sequence 
>C. ELEGANS:190739_AT
aggataattcatctggttttactccaatgagcagaattccattccaagttctttacaaaa
tcatttatgaaatttgtgatggaatcgaatatatccattcaagaaaccttgttcatcgtg
atttaactgcaagaaatgttcttctaactactggactaagagcgaaaatttctggatttg
gattttgttctgagccagatgatcccaaatttgctgcaaattcacttgctcttcggtatc
ttcctgtgagatggcttgcaccagagtgttttattggaaaattcagtgttaaaagtgata
gttggtcatttggagtactgatgtatgaaatgttctcattaggtgaacagccatatgaag
atttaattcgaccagaggaaataattgaaagtatccgaaaaggaagagttccagcccatc
caaaatattgttctaagcaaacgtacaaaattatgcaaagttgttatcaatcattcatgt
cacgacgtccaaactttactcaattgaaaaatgcattccatgttcagtctactaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AGGATAATTCATCTGGTTTTACTCC 692 53 1625 Antisense
GAATTCCATTCCAAGTTCTTTACAA 132 325 1658 Antisense
GAAATGTTCTTCTAACTACTGGACT 682 361 1757 Antisense
GTTCTGAGCCAGATGATCCCAAATT 66 443 1811 Antisense
GCTGCAAATTCACTTGCTCTTCGGT 438 297 1837 Antisense
CTCTTCGGTATCTTCCTGTGAGATG 402 229 1853 Antisense
GAGATGGCTTGCACCAGAGTGTTTT 247 395 1872 Antisense
AGTTCCAGCCCATCCAAAATATTGT 372 63 2031 Antisense
ATCAATCATTCATGTCACGACGTCC 455 25 2090 Antisense
TCACGACGTCCAAACTTTACTCAAT 656 625 2104 Antisense
ATGCATTCCATGTTCAGTCTACTAA 637 41 2135 Antisense
Sequence Source Affymetrix Proprietary Database