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[190738_at] Aldo/keto reductase

Description ZK1290.5 /REP_DB=WormBase Gene ID /WP=CE15543 /TR=SW:Q09632 /GB=AAB93322.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation /DEF=Aldo-keto reductase
Cluster 6grp_highest_10_10 > 18      6grp_high1_10_10 > 80      4grp_highest_8_8 > 22      4grp_high_8_8 > 06      6grp_highest_nonorm > 62      6grp_total > 72      4grp_total > 01      6grp_highest_sub > 04_05      6grp_high1_sub > 02_03_04_05      6grp_total_sub > Hat      6grp_rule_based > S3      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1421
1 2 3 4 range
A 206.5
(-2.9)
P 		188.4
(-3)
P 		338.2
(-2.2)
P 		1253
(3)
P 		1065
B 188.5
(-3)
P 		269.5
(-2.7)
P 		207.6
(-2.9)
P 		1609.5
(3)
P 		1421
C 240.6
(-3)
P 		265.7
(-2.8)
P 		298
(-2.6)
P 		1152.1
(3)
P 		912
avr 211.9
(-3) 		241.2
(-2.8) 		281.3
(-2.6) 		1338.2
(3) 		1126

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 407
1 2 3 4 5 6 range
A 292
(-3)
P 		543.9
(0.9)
P 		678.7
(3)
P 		666.7
(2.8)
P 		607.7
(1.9)
P 		437.5
(-0.7)
P 		387
B 330.3
(-3)
P 		541.2
(1.3)
P 		621.6
(3)
P 		591.9
(2.4)
P 		555
(1.6)
P 		414.1
(-1.3)
P 		291
C 272.1
(-3)
P 		657.8
(3)
P 		494.4
(0.5)
P 		501
(0.6)
P 		547.6
(1.3)
P 		446.8
(-0.3)
P 		386
avr 298.1
(-3) 		581
(2.7) 		598.2
(3) 		586.5
(2.8) 		570.1
(2.4) 		432.8
(-0.3) 		300
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 302
1 2 3 4 range
A 75.2
(-1.6)
P 		40.9
(-3)
P 		88.4
(-1)
P 		183.4
(3)
P 		143
B 60.1
(-2.8)
P 		66.6
(-2.6)
P 		48.1
(-3)
P 		343
(3)
P 		295
C 79.6
(-2.8)
P 		76.4
(-3)
P 		103.8
(-1.6)
P 		194.3
(3)
P 		118
avr 71.6
(-2.7) 		61.3
(-3) 		80.1
(-2.4) 		240.2
(3) 		179

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 172
1 2 3 4 5 6 range
A 53.8
(-3)
P 		193.4
(3)
P 		147.8
(1)
P 		169.1
(2)
P 		183.4
(2.6)
P 		106.5
(-0.7)
P 		140
B 114.9
(-3)
P 		180.1
(0.5)
P 		150.9
(-1)
P 		156.8
(-0.7)
P 		225.5
(3)
P 		154.4
(-0.9)
P 		111
C 100.8
(-3)
P 		200.7
(3)
P 		125.8
(-1.5)
P 		100.7
(-3)
P 		177.2
(1.6)
P 		149.6
(-0.1)
P 		100
avr 89.8
(-3) 		191.4
(2.8) 		141.5
(-0.1) 		142.2
(-0) 		195.4
(3) 		136.8
(-0.3) 		106
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190738_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.4711
Sequence Type Exemplar sequence
Representative Public ID ZK1290.5 NCBI
Target Description ZK1290.5 /REP_DB=WormBase Gene ID /WP=CE15543 /TR=SW:Q09632 /GB=AAB93322.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation /DEF=Aldo-keto reductase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_063177(10)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_063177 NCBI Caenorhabditis elegans ZK1290.5 (ZK1290.5) mRNA, complete cds. 10/11 None
SNAP00000002671 ENSEMBL cdna:SNAP chromosome:CEL140:II:7529569:7533063:1 10/11 None
GENEFINDER00000002688 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:7529569:7533063:1 10/11 None
ZK1290.5 ENSEMBL cdna:known chromosome:CEL140:II:7529569:7530750:1 gene:ZK1290.5 10/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:7529565-7530747(+) 100.0 100.0
Public Domain and Genome References
Gene Title Aldo/keto reductase
Ensembl ZK1290.5
Entrez Gene 191555 Entrez gene
SwissProt Q09632 EMBL-EBI
WormBase CE36068 Wormbase
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast AAB93322 Hypothetical protein ZK1290.5 [Caenorhabditis elegans] ref|NP_495578.2| ZK1290.5 [Caenorhabditis elegans] sp|Q09632|YOF5_CAEEL Probable oxidoreductase ZK1290.5 in chromosome II 0.0
blast AAB93321 Warthog (hedgehog-like family) protein 1 [Caenorhabditis elegans] ref|NP_495579.3| WaRThog (hedgehog-like family) family member (wrt-1) [Caenorhabditis elegans] 0.0
blast Q94128 Warthog protein 1 precursor [Contains: Warthog protein 1 N-product; Warthog protein 1 C-product] gb|AAB17540.1| ZK [Caenorhabditis elegans] 0.0
blast CAE67482 Hypothetical protein CBG12986 [Caenorhabditis briggsae] 0.0
blast CAE67481 Hypothetical protein CBG12985 [Caenorhabditis briggsae] 1.0E-160
Protein Domains
Database ID Description E-Value
Pfam IPR001395 EMBL-EBI Aldo/keto reductase 5.4E-81
Pfam IPR001767 EMBL-EBI Peptidase C46, hedgehog protein, hint region 9.7E-35
Pfam IPR001395 EMBL-EBI Aldo/keto reductase 1.4E-81
Pfam IPR001767 EMBL-EBI Peptidase C46, hedgehog protein, hint region 9.7E-35
Pfam IPR001395 EMBL-EBI Aldo/keto reductase 3.9E-83
Trans Membrane
ID Number Of Domains Domain Boundaries
GENEFINDER00000002688 2 341-363,416-438
Sequence
Target Sequence 
>C. ELEGANS:190738_AT
aatccccaaactaatttcactatcattacagaacatgtccgttcaattggtgttagtaat
tattcaatcgaagatctagacgagttattagagtttgcaagtatccttccacatgctaat
caagtagaacttcatccatggttccaccaggccgacctcaaaaattattgcgatgaactg
gggattctcacgatgggttactgtccacttgccaagggaaagtatttggaagatgaaacg
ctctgtaaaattgcttcaaaatatcaaaaatctccggcacaaatctgtcttcgttggagt
attcaacaaaacgttccaactgttccaaaaagtacagactgtcgcagattgaaagagaac
acgaatgtttttgattttgagctgtctgcagaagatatgaacactttgaactcattctca
tctcaaaatcgaaagattgtcgatctatcaaacatttgccaaaaaatgtctcttcctgac
ggctacaagttaaatggacgagtcttcggagttccag

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AATCCCCAAACTAATTTCACTATCA 449 167 550 Antisense
GCAAGTATCCTTCCACATGCTAATC 315 321 646 Antisense
GTAGAACTTCATCCATGGTTCCACC 84 457 673 Antisense
GAACTGGGGATTCTCACGATGGGTT 414 327 724 Antisense
TCACGATGGGTTACTGTCCACTTGC 418 627 737 Antisense
AAATCTCCGGCACAAATCTGTCTTC 576 117 817 Antisense
GTTTTTGATTTTGAGCTGTCTGCAG 450 449 916 Antisense
AACACTTTGAACTCATTCTCATCTC 675 135 949 Antisense
TTTGCCAAAAAATGTCTCTTCCTGA 101 669 1004 Antisense
TCTCTTCCTGACGGCTACAAGTTAA 191 613 1018 Antisense
AATGGACGAGTCTTCGGAGTTCCAG 707 161 1042 Antisense
Sequence Source Affymetrix Proprietary Database