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[190737_at]

Description F09C12.2 /REP_DB=WormBase Gene ID /WP=CE02602 /TR=Q19243 /GB=AAA68345.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation /DEF=Ser-Thr protein kinase
Cluster 6grp_total > 98      4grp_total > 28      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 43
1 2 3 4 range
A 22.1
(-2.8)
A 		21.6
(-2.9)
A 		21.3
(-3)
A 		51.5
(3)
A 		30
B 16.4
(-0.3)
A 		26.7
(3)
A 		12.3
(-1.6)
A 		8.1
(-3)
A 		19
C 31.4
(3)
A 		23.6
(0.9)
A 		9.2
(-3)
A 		20.2
(-0)
A 		22
avr 23.3
(1.4) 		24
(1.7) 		14.3
(-3) 		26.6
(3) 		12

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 229
1 2 3 4 5 6 range
A 12.9
(-2.9)
A 		10.3
(-3)
A 		10.1
(-3)
A 		12.1
(-2.9)
A 		163.1
(1.1)
A 		232
(3)
P 		222
B 8
(-2.9)
A 		10.7
(-2.8)
A 		3.4
(-3)
A 		12.5
(-2.7)
A 		150.2
(1.2)
A 		214.4
(3)
A 		211
C 11.2
(-2.8)
A 		20.6
(-2.6)
A 		4.9
(-3)
A 		27.9
(-2.4)
A 		132.6
(0.6)
A 		220.7
(3)
M 		216
avr 10.7
(-2.9) 		13.9
(-2.8) 		6.1
(-3) 		17.5
(-2.7) 		148.6
(1) 		222.4
(3) 		216
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 9
1 2 3 4 range
A 8.1
(3)
A 		4.7
(-3)
A 		5.6
(-1.4)
A 		7.5
(1.9)
A 		3
B 5.2
(1.3)
A 		6.6
(3)
A 		2.8
(-1.7)
A 		1.7
(-3)
A 		5
C 10.4
(3)
A 		6.8
(-0)
A 		3.2
(-3)
A 		3.4
(-2.8)
A 		7
avr 7.9
(3) 		6
(0.2) 		3.9
(-3) 		4.2
(-2.6) 		4

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 79
1 2 3 4 5 6 range
A 2.4
(-3)
A 		3.7
(-2.8)
A 		2.2
(-3)
A 		3.1
(-2.9)
A 		49.2
(2.2)
A 		56.5
(3)
P 		54
B 2.8
(-2.8)
A 		3.6
(-2.8)
A 		0.8
(-3)
A 		3.3
(-2.8)
A 		61
(1.6)
A 		79.9
(3)
A 		79
C 4.1
(-2.8)
A 		6.3
(-2.6)
A 		1.2
(-3)
A 		5.6
(-2.6)
A 		42.9
(0.4)
A 		73.9
(3)
M 		73
avr 3.1
(-2.9) 		4.5
(-2.7) 		1.4
(-3) 		4
(-2.8) 		51
(1.3) 		70.1
(3) 		69
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190737_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.5500
Sequence Type Exemplar sequence
Representative Public ID F09C12.2 NCBI
Target Description F09C12.2 /REP_DB=WormBase Gene ID /WP=CE02602 /TR=Q19243 /GB=AAA68345.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation /DEF=Ser-Thr protein kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_062547(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_062547 NCBI Caenorhabditis elegans F09C12.8 (F09C12.8) mRNA, complete cds. 11/11 None
SNAP00000009138 ENSEMBL cdna:SNAP chromosome:CEL140:II:5111113:5114108:1 11/11 None
GENEFINDER00000009154 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:5107911:5114108:1 11/11 None
F09C12.8 ENSEMBL cdna:known chromosome:CEL140:II:5112741:5114108:1 gene:F09C12.8 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:5110008-5114106(+) 100.0 100.0
Public Domain and Genome References
Gene Title
Ensembl F09C12.8
Entrez Gene 173881 Entrez gene
SwissProt Q8IG34 EMBL-EBI
WormBase CE32360 Wormbase
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast T15983 hypothetical protein F09C12.2 - Caenorhabditis elegans 0.0
blast AAN63410 Hypothetical protein F09C12.2 [Caenorhabditis elegans] ref|NP_872069.1| F09C12.2 [Caenorhabditis elegans] 0.0
blast AAN63411 Hypothetical protein F09C12.8 [Caenorhabditis elegans] ref|NP_494948.2| F09C12.8 [Caenorhabditis elegans] 1.0E-172
blast T15983 hypothetical protein F09C12.2 - Caenorhabditis elegans 1.0E-172
blast AAN63411 Hypothetical protein F09C12.8 [Caenorhabditis elegans] ref|NP_494948.2| F09C12.8 [Caenorhabditis elegans] 1.0E-171
blast AAN63411 Hypothetical protein F09C12.8 [Caenorhabditis elegans] ref|NP_494948.2| F09C12.8 [Caenorhabditis elegans] 1.0E-167
blast CAE73224 Hypothetical protein CBG20630 [Caenorhabditis briggsae] 1.0E-151
Protein Families
Method ID Description E-Value
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 7.0E-70
hanks 3.1.1 CMCG Group; CMGC I Cyclin-dependent (CDKs) and close relatives; CDC2Hs 1.0E-74
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 5.5E-27
Pfam IPR000719 EMBL-EBI Protein kinase 6.0E-83
Sequence
Target Sequence 
>C. ELEGANS:190737_AT
caccagatgtaatctactgctccccatcacttcgttgcattcaaactgccacttgggtcc
gtgaaatgtcgggaagtaaagcattgcttcgtgttgaacctggacttttcgagaacttcc
attatccacacggagttccacgattcatcagccaacttcaacgacacgtgttcccagtgg
acaagacgttccgcccgttcctttctttggagacagtcgttggaaaacaagagacaaatg
acgagtataatgcaaggatccaattgattttgaatgcaattgcggatcaatcggaagttt
caactgtcgagaaagaactgaaagttctcgtggtggctcacgcttctacagttgatatgg
ctgttggattgctcagagaagtgccgagaaaaattagagaagaggaattggataatattg
caattcctgtcccatactgctctctcgcatatctcaaaaagaaatgcaactactgggttc
cagcggctcatcaagttccatcggtgacctacgagtt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CACCAGATGTAATCTACTGCTCCCC 257 201 1529 Antisense
TCAAACTGCCACTTGGGTCCGTGAA 480 629 1569 Antisense
TTCGAGAACTTCCATTATCCACACG 277 697 1636 Antisense
TCCACACGGAGTTCCACGATTCATC 255 589 1653 Antisense
CGATTCATCAGCCAACTTCAACGAC 347 247 1669 Antisense
TCAACGACACGTGTTCCCAGTGGAC 80 631 1686 Antisense
GAAAGTTCTCGTGGTGGCTCACGCT 231 361 1848 Antisense
GGCTCACGCTTCTACAGTTGATATG 300 539 1863 Antisense
TAATATTGCAATTCCTGTCCCATAC 268 635 1941 Antisense
TGCAACTACTGGGTTCCAGCGGCTC 681 575 1993 Antisense
AAGTTCCATCGGTGACCTACGAGTT 522 155 2021 Antisense
Sequence Source Affymetrix Proprietary Database