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[190731_s_at] fork head domain protein

Description C47G2.2 /REP_DB=WormBase Gene ID /WP=CE02166 /TR=Q18694 /GB=CAA88935.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=fork head domain protein
Cluster 6grp_highest_10_10 > 54      6grp_high1_10_10 > 45      4grp_highest_8_8 > 58      4grp_high_8_8 > 33      6grp_highest_nonorm > 90      6grp_total > 90      4grp_total > 46      6grp_cgc > 26      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 196
1 2 3 4 range
A 236.3
(3)
P 		154.1
(-1)
P 		144.8
(-1.4)
P 		112.8
(-3)
P 		124
B 305.9
(3)
P 		163.6
(-2.8)
P 		157.9
(-3)
P 		160.9
(-2.9)
P 		148
C 308.3
(3)
P 		213.8
(-0.9)
P 		162.4
(-3)
P 		196.2
(-1.6)
P 		146
avr 283.5
(3) 		177.2
(-2) 		155
(-3) 		156.6
(-2.9) 		129

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 181
1 2 3 4 5 6 range
A 224.7
(1.5)
P 		249.8
(2.6)
P 		115.4
(-3)
P 		167.4
(-0.8)
P 		214.5
(1.1)
P 		260.5
(3)
P 		145
B 207.7
(0.3)
P 		218.5
(0.7)
P 		175.4
(-0.8)
P 		289.2
(3)
P 		108.6
(-3)
P 		154.9
(-1.5)
P 		181
C 155.6
(-1.6)
P 		228.6
(1.4)
P 		164.2
(-1.3)
P 		266
(3)
P 		123
(-3)
P 		176.3
(-0.8)
P 		143
avr 196
(0.1) 		232.3
(2.4) 		151.7
(-2.8) 		240.9
(3) 		148.7
(-3) 		197.2
(0.2) 		92
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 86
1 2 3 4 range
A 86.1
(3)
P 		33.4
(-1.5)
P 		37.8
(-1.2)
P 		16.5
(-3)
P 		70
B 97.5
(3)
P 		40.4
(-2.4)
P 		36.6
(-2.8)
P 		34.3
(-3)
P 		63
C 102
(3)
P 		61.5
(-0.5)
P 		56.6
(-1)
P 		33.1
(-3)
P 		69
avr 95.2
(3) 		45.1
(-1.5) 		43.7
(-1.6) 		28
(-3) 		67

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 64
1 2 3 4 5 6 range
A 41.4
(-1.5)
P 		88.9
(3)
P 		25.1
(-3)
P 		42.4
(-1.4)
P 		64.7
(0.7)
P 		63.4
(0.6)
P 		64
B 72.3
(2.2)
P 		72.7
(2.3)
P 		42.6
(-3)
P 		76.6
(3)
P 		44.1
(-2.7)
P 		57.8
(-0.3)
P 		34
C 57.7
(0.6)
P 		69.8
(3)
P 		41.8
(-2.6)
P 		53.5
(-0.3)
P 		39.8
(-3)
P 		59
(0.8)
P 		30
avr 57.1
(0) 		77.1
(3) 		36.5
(-3) 		57.5
(0.1) 		49.5
(-1.1) 		60.1
(0.5) 		41
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 190731_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.3063
Sequence Type Exemplar sequence
Representative Public ID C47G2.2 NCBI
Target Description C47G2.2 /REP_DB=WormBase Gene ID /WP=CE02166 /TR=Q18694 /GB=CAA88935.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=fork head domain protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_064010(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_064010 NCBI Caenorhabditis elegans UNCoordinated family member (unc-130) (unc-130) mRNA, complete cds. 11/11 None
SNAP00000012594 ENSEMBL cdna:SNAP chromosome:CEL140:II:11281901:11283576:1 11/11 None
GENEFINDER00000012606 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:11281901:11283576:1 11/11 None
C47G2.2 ENSEMBL cdna:known chromosome:CEL140:II:11281892:11283847:1 gene:C47G2.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:11281897-11283573(+) 100.0 100.0
Public Domain and Genome References
Gene Title fork head domain protein
Gene Symbol unc-130
Ensembl C47G2.2
Entrez Gene 174721 Entrez gene
SwissProt Q18694 EMBL-EBI
WormBase CE02166 Wormbase
Functional Annotations
Ortholog
ID Title Organism
U133_X3P:HS.272339.0.S1_3P_AT forkhead box D4 hs
HG-U95D:82251_AT forkhead box D4 hs
HG-U133_PLUS_2:1567341_AT forkhead box D4 hs
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6355 regulation of transcription, DNA-dependent inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5634 nucleus inferred from electronic annotation QuickGO AmiGO
5634 nucleus inferred from direct assay QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3700 transcription factor activity inferred from electronic annotation QuickGO AmiGO
3700 transcription factor activity inferred from sequence similarity QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA88935 Hypothetical protein C47G2.2 [Caenorhabditis elegans] ref|NP_496411.1| UNCoordinated family member (unc-130) [Caenorhabditis elegans] 1.0E-133
blast CAE59541 Hypothetical protein CBG02936 [Caenorhabditis briggsae] 1.0E-86
blast CAC12963 winged helix transcription factor [Xenopus laevis] dbj|BAA36334.1| XFD-6 [Xenopus laevis] 5.0E-47
Protein Domains
Database ID Description E-Value
scop a.4.5.Forkhead DNA-binding domain All alpha proteins; DNA/RNA-binding 3-helical bundle; "Winged helix" DNA-binding domain; Forkhead DNA-binding domain 8.99997951697257E-41
Pfam IPR001766 EMBL-EBI Fork head transcription factor 9.6E-64
Sequence
Target Sequence 
>C. ELEGANS:190731_S_AT
tcctacattgcactcatcgcgatgtcaattctcaattcaccggagaagaaactgacactt
tcggaaatttgcgagttcataatcaataagttcgagtattacaaggagaagttccccgcc
tggcagaactcgattcgtcacaacctaagcctcaacgactgttttgtgaaggtggctcgg
gggcctgggaatccgggaaaaggaaactattgggcgctggatccgaactgtgaggatatg
ttcgacaatggatcgtttctgcgcagaaggaagagatacaagaaaaacagtgacacatat
cacgaaatgatgtcccatcatccgatgccattccctccattcctcccgcaaggaatgccc
tttcctccaagaatgatgcacccgatggctaacattcccatgctgggacatccaatgaat
ccaagagcagttccaaacatgccagcgttcttcattccacaaaatattgatagccagaag
ctcttgtcaatgatggcttcgagaataatgccaatggatgctccagtcagctctggccag
aagagaacttcatcgagctcctca

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TCCTACATTGCACTCATCGCGATGT 689 591 403 Antisense
TCATCGCGATGTCAATTCTCAATTC 666 619 416 Antisense
GAACTCGATTCGTCACAACCTAAGC 262 349 528 Antisense
ACAACCTAAGCCTCAACGACTGTTT 312 107 542 Antisense
ACTATTGGGCGCTGGATCCGAACTG 311 101 608 Antisense
GACAATGGATCGTTTCTGCGCAGAA 382 365 646 Antisense
GCCCTTTCCTCCAAGAATGATGCAC 189 287 759 Antisense
ACCCGATGGCTAACATTCCCATGCT 118 91 782 Antisense
TTCCAAACATGCCAGCGTTCTTCAT 591 701 833 Antisense
CCAATGGATGCTCCAGTCAGCTCTG 563 275 913 Antisense
GAAGAGAACTTCATCGAGCTCCTCA 613 337 942 Antisense
Sequence Source Affymetrix Proprietary Database