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[190718_s_at] MEF-2 protein

Description W10D5.1 /REP_DB=WormBase Gene ID /WP=CE25156 /GEN=mef-2 /TR=Q9U325 /GB=CAB61037.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=MEF-2 protein
Cluster 6grp_total > 27      4grp_total > 01      6grp_cgc > 06      6grp_cgc_sub > Cu      6grp_total_sub > Decrease      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 663
1 2 3 4 range
A 361.6
(-1.4)
A 		288.3
(-2.5)
A 		257.1
(-3)
A 		658.2
(3)
A 		401
B 250.9
(-3)
A 		259.6
(-2.9)
A 		397.8
(-1.7)
A 		914.3
(3)
P 		663
C 360.3
(-1.7)
A 		269.2
(-3)
A 		317.1
(-2.3)
A 		695.7
(3)
A 		427
avr 324.3
(-2.4) 		272.4
(-3) 		324
(-2.4) 		756.1
(3) 		484

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 475
1 2 3 4 5 6 range
A 501.1
(3)
A 		207
(-0.7)
A 		121.7
(-1.8)
A 		25.8
(-3)
A 		140.5
(-1.6)
A 		195.7
(-0.9)
A 		475
B 344.5
(3)
A 		221.6
(0.7)
A 		66.1
(-2.3)
A 		26.4
(-3)
A 		69.1
(-2.2)
A 		131.8
(-1)
A 		318
C 460.5
(3)
A 		164.4
(-1.1)
A 		25.7
(-3)
A 		120.2
(-1.7)
A 		85
(-2.2)
A 		166.2
(-1.1)
A 		435
avr 435.4
(3) 		197.7
(-0.8) 		71.2
(-2.8) 		57.5
(-3) 		98.2
(-2.4) 		164.6
(-1.3) 		378
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 132
1 2 3 4 range
A 131.7
(3)
A 		62.6
(-3)
A 		67.2
(-2.6)
A 		96.3
(-0.1)
A 		69
B 80
(-2.3)
A 		64.1
(-3)
A 		92.2
(-1.7)
A 		194.8
(3)
P 		131
C 119.3
(3)
A 		77.4
(-3)
A 		110.5
(1.7)
A 		117.3
(2.7)
A 		42
avr 110.3
(0.7) 		68
(-3) 		90
(-1.1) 		136.1
(3) 		68

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 164
1 2 3 4 5 6 range
A 92.4
(3)
A 		73.6
(1.7)
A 		26.5
(-1.6)
A 		6.6
(-3)
A 		42.4
(-0.5)
A 		47.6
(-0.1)
A 		86
B 119.9
(3)
A 		73.7
(0.5)
A 		16.1
(-2.5)
A 		7
(-3)
A 		28.1
(-1.9)
A 		49.2
(-0.8)
A 		113
C 170.7
(3)
A 		50.2
(-1.4)
A 		6.5
(-3)
A 		24.2
(-2.4)
A 		27.5
(-2.2)
A 		55.6
(-1.2)
A 		164
avr 127.7
(3) 		65.8
(-0.2) 		16.4
(-2.8) 		12.6
(-3) 		32.7
(-2) 		50.8
(-1) 		115
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 190718_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.1208
Sequence Type Exemplar sequence
Representative Public ID W10D5.1 NCBI
Target Description W10D5.1 /REP_DB=WormBase Gene ID /WP=CE25156 /GEN=mef-2 /TR=Q9U325 /GB=CAB61037.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=MEF-2 protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_060040(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_060040 NCBI Caenorhabditis elegans related to vertebrate MEF2 transcription factor family member (mef-2) (mef-2) mRNA, complete cds. 11/11 A 
SNAP00000007418 ENSEMBL cdna:SNAP chromosome:CEL140:I:9106296:9108182:1 11/11 None
GENEFINDER00000007425 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:9106296:9108182:1 11/11 None
W10D5.1 ENSEMBL cdna:known chromosome:CEL140:I:9104081:9108951:1 gene:W10D5.1 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:9104066-9108113(+) 90.13 100.0
Public Domain and Genome References
Gene Title MEF-2 protein
Gene Symbol mef-2
Ensembl W10D5.1
Entrez Gene 172732 Entrez gene
SwissProt Q9U325 EMBL-EBI
WormBase CE25156 Wormbase
Functional Annotations
Ortholog
ID Title Organism
HG-U133A:203003_AT MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) hs
HG-U133A_2:203003_AT MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) hs
HG-FOCUS:203003_AT MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) hs
HG-U133_PLUS_2:203003_AT MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) hs
HU35KSUBA:L16794_S_AT MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) hs
HU35KSUBB:RC_W46329_AT MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) hs
HU35KSUBC:RC_AA485060_AT MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) hs
HU35KSUBD:RC_AA227511_S_AT MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) hs
HG-U133A:203004_S_AT MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) hs
HG-U133_PLUS_2:203004_S_AT MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) hs
HG-U133A_2:203004_S_AT MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) hs
U133_X3P:G5174544_3P_A_AT MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) hs
U133_X3P:HS.77955.0.S1_3P_AT MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) hs
U133_X3P:HS.111243.0.A2_3P_X_AT MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) hs
U133_X3P:HS.111243.0.A2_3P_AT MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) hs
HG-U133_PLUS_2:225641_AT MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) hs
HG-U133B:225641_AT MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) hs
HG-U95AV2:35434_AT MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) hs
HG-U95B:54969_AT MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) hs
HG-U95B:56968_AT MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) hs
HG-U95E:88219_AT MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) hs
MOUSE430A_2:1421388_AT myocyte enhancer factor 2D mm
MOE430A:1421388_AT myocyte enhancer factor 2D mm
MOUSE430_2:1421388_AT myocyte enhancer factor 2D mm
MU11KSUBA:AA408983_RC_G_AT myocyte enhancer factor 2D mm
MU11KSUBA:AA408983_RC_AT myocyte enhancer factor 2D mm
MG-U74AV2:104241_AT myocyte enhancer factor 2D mm
MG-U74BV2:115085_AT myocyte enhancer factor 2D mm
MOE430A:1434487_AT myocyte enhancer factor 2D mm
MOUSE430A_2:1434487_AT myocyte enhancer factor 2D mm
MOUSE430_2:1434487_AT myocyte enhancer factor 2D mm
MOE430B:1437300_AT myocyte enhancer factor 2D mm
MOUSE430_2:1437300_AT myocyte enhancer factor 2D mm
MG-U74CV2:140567_AT Myocyte enhancer factor 2D (Mef2d), mRNA mm
MU11KSUBA:AA409010_RC_AT Myocyte enhancer factor 2D (Mef2d), mRNA mm
MU19KSUBB:TC31371_AT Myocyte enhancer factor 2D (Mef2d), mRNA mm
MU19KSUBC:TC37235_AT Myocyte enhancer factor 2D (Mef2d), mRNA mm
MU19KSUBC:TC40093_AT Myocyte enhancer factor 2D (Mef2d), mRNA mm
RT-U34:AJ005425_AT myocyte enhancer factor 2D rn
RG-U34A:AJ005425_AT myocyte enhancer factor 2D rn
RAE230A:1369851_AT myocyte enhancer factor 2D rn
RAT230_2:1369851_AT myocyte enhancer factor 2D rn
RAE230A:1398427_AT Myocyte enhancer factor 2D rn
RAT230_2:1398427_AT Myocyte enhancer factor 2D rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6355 regulation of transcription, DNA-dependent inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5634 nucleus inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3700 transcription factor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB61037 Hypothetical protein W10D5.1 [Caenorhabditis elegans] ref|NP_492441.1| related to vertebrate MEF2 transcription factor family member (mef-2) [Caenorhabditis elegans] 1.0E-142
blast T26328 hypothetical protein W10D5.1 - Caenorhabditis elegans 1.0E-140
blast AAA79337 CeMEF-2 gb|AAA79336.1| CeMef-2 1.0E-140
blast CAB61037 Hypothetical protein W10D5.1 [Caenorhabditis elegans] ref|NP_492441.1| related to vertebrate MEF2 transcription factor family member (mef-2) [Caenorhabditis elegans] 1.0E-132
blast CAB61037 Hypothetical protein W10D5.1 [Caenorhabditis elegans] ref|NP_492441.1| related to vertebrate MEF2 transcription factor family member (mef-2) [Caenorhabditis elegans] 1.0E-131
blast T26328 hypothetical protein W10D5.1 - Caenorhabditis elegans 1.0E-130
blast AAA79337 CeMEF-2 gb|AAA79336.1| CeMef-2 1.0E-130
Protein Domains
Database ID Description E-Value
Pfam IPR002100 EMBL-EBI Transcription factor, MADS-box 1.6E-25
Pfam IPR002100 EMBL-EBI Transcription factor, MADS-box 8.6E-20
Pfam IPR002100 EMBL-EBI Transcription factor, MADS-box 1.6E-19
Sequence
Target Sequence 
>C. ELEGANS:190718_S_AT
gctgccgctgttgcagcagcagcagccgcagttgcagcagttgagggaacatcttcgggt
gcggctgctgcagcggctgcactacaagcatcaaatgctcaacgacatcataatttgaac
ttgtaccagaatttgatatttaatcccaactacactcgccatttgaaccaaagaaatgat
cctctgtcctctacatctgttgctccttcctcatcctcatcaaaacatctcgattttcct
ccatcaacttcatttgcctatgacacgtcacgccttcatccaattgccgctgctgatgct
gattgtgatcttgtaccatcatcaagagctgcagctgatcaaaatatttggtcatctgca
ttacaacaacgccctgtttcacagcctgcacctagtataagcaattcatcaacaaacgga
atctcaaacggaacttcatcactcttatctccaaatgtcagctc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GCTGCCGCTGTTGCAGCAGCAGCAG 187 297 424 Antisense
CAGCGGCTGCACTACAAGCATCAAA 333 203 494 Antisense
ACTACACTCGCCATTTGAACCAAAG 565 99 572 Antisense
AAAGAAATGATCCTCTGTCCTCTAC 594 123 593 Antisense
TCAAAACATCTCGATTTTCCTCCAT 7 631 643 Antisense
TCATTTGCCTATGACACGTCACGCC 380 619 673 Antisense
TTGCCGCTGCTGATGCTGATTGTGA 562 701 707 Antisense
TCATCTGCATTACAACAACGCCCTG 149 621 775 Antisense
GTTTCACAGCCTGCACCTAGTATAA 708 449 799 Antisense
ACGGAACTTCATCACTCTTATCTCC 697 95 851 Antisense
CACTCTTATCTCCAAATGTCAGCTC 143 197 863 Antisense
Sequence Source Affymetrix Proprietary Database