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[190712_at] aldehyde dehydrogenase

Description K04F1.15 /REP_DB=WormBase Gene ID /WP=CE23852 /TR=Q9TXM0 /GB=AAC78174.2 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=aldehyde dehydrogenase
Cluster 6grp_total > 87      4grp_total > 03      6grp_cgc > 68      6grp_cgc_sub > In      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 22
1 2 3 4 range
A 1.9
(-3)
A 		3.4
(-2.6)
A 		2.9
(-2.7)
A 		23.6
(3)
A 		22
B 8.7
(-0)
A 		8.8
(0)
A 		2.6
(-3)
A 		14.8
(3)
A 		12
C 8.5
(3)
A 		3.7
(-3)
A 		6.6
(0.6)
A 		7.7
(2)
A 		5
avr 6.4
(-1.7) 		5.3
(-2.3) 		4
(-3) 		15.4
(3) 		11

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 56
1 2 3 4 5 6 range
A 2.8
(-2.9)
A 		2.2
(-3)
A 		7
(-2.5)
A 		24
(-0.6)
A 		57.8
(3)
A 		49.2
(2.1)
A 		56
B 5.7
(-2.7)
A 		13.8
(-1.5)
A 		6.3
(-2.6)
A 		3.9
(-3)
A 		14
(-1.4)
A 		42.7
(3)
A 		39
C 2
(-3)
A 		2.6
(-2.9)
A 		3.9
(-2.8)
A 		20.7
(-0.8)
A 		6.6
(-2.5)
A 		53.9
(3)
A 		52
avr 3.5
(-3) 		6.2
(-2.6) 		5.7
(-2.7) 		16.2
(-1.3) 		26.1
(0) 		48.6
(3) 		45
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 3
1 2 3 4 range
A 0.7
(-3)
A 		0.7
(-3)
A 		0.8
(-2.8)
A 		3.5
(3)
A 		3
B 2.8
(2.3)
A 		2.2
(0.8)
A 		0.6
(-3)
A 		3.1
(3)
A 		3
C 2.8
(3)
A 		1.1
(-3)
A 		2.3
(1.2)
A 		1.3
(-2.3)
A 		2
avr 2.1
(0.9) 		1.3
(-2.6) 		1.2
(-3) 		2.6
(3) 		1

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 18
1 2 3 4 5 6 range
A 0.5
(-3)
A 		0.8
(-2.9)
A 		1.5
(-2.6)
A 		6.1
(-1)
A 		17.5
(3)
A 		12
(1.1)
A 		17
B 2
(-2.6)
A 		4.6
(-1.6)
A 		1.5
(-2.8)
A 		1
(-3)
A 		5.7
(-1.1)
A 		15.9
(3)
A 		15
C 0.7
(-3)
A 		0.8
(-3)
A 		1
(-2.9)
A 		4.2
(-1.8)
A 		2.1
(-2.5)
A 		18
(3)
A 		17
avr 1.1
(-3) 		2.1
(-2.6) 		1.3
(-2.9) 		3.8
(-1.9) 		8.4
(0.1) 		15.3
(3) 		14
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190712_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.15121
Sequence Type Exemplar sequence
Representative Public ID K04F1.15 NCBI
Target Description K04F1.15 /REP_DB=WormBase Gene ID /WP=CE23852 /TR=Q9TXM0 /GB=AAC78174.2 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=aldehyde dehydrogenase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_071066(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_071066 NCBI Caenorhabditis elegans ALdehyde deHydrogenase family member (alh-2) (alh-2) mRNA, complete cds. 11/11 None
SNAP00000011958 ENSEMBL cdna:SNAP chromosome:CEL140:V:1644459:1650200:1 11/11 None
GENEFINDER00000011973 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:1644206:1647557:1 11/11 None
K04F1.15 ENSEMBL cdna:known chromosome:CEL140:V:1644206:1647557:1 gene:K04F1.15 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:1644205-1647557(+) 100.0 100.0
Public Domain and Genome References
Gene Title aldehyde dehydrogenase
Gene Symbol alh-2
Ensembl K04F1.15
Entrez Gene 187001 Entrez gene
SwissProt Q9TXM0 EMBL-EBI
WormBase CE23852 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:265188_AT aldehyde dehydrogenase, mitochondrial (ALDH3) at
ATGENOME1:13549_AT aldehyde dehydrogenase, mitochondrial (ALDH3) at
CANINE_2:CFA.2170.1.S1_AT similar to aldehyde dehydrogenase 1B1 precursor cfa
CANINE_2:CFAAFFX.4463.1.S1_AT similar to aldehyde dehydrogenase 1B1 precursor cfa
HG-U133_PLUS_2:209646_X_AT aldehyde dehydrogenase 1 family, member B1 hs
HG-U133A:209646_X_AT aldehyde dehydrogenase 1 family, member B1 hs
HG-U133A_2:209646_X_AT aldehyde dehydrogenase 1 family, member B1 hs
HUGENEFL:M63967_AT aldehyde dehydrogenase 1 family, member B1 hs
U133_X3P:G12804426_3P_A_AT aldehyde dehydrogenase 1 family, member B1 hs
U133_X3P:HS.169517.0.S1_3P_A_AT aldehyde dehydrogenase 1 family, member B1 hs
U133_X3P:209646_3P_X_AT aldehyde dehydrogenase 1 family, member B1 hs
HG-U133A_2:209645_S_AT aldehyde dehydrogenase 1 family, member B1 hs
HG-FOCUS:209645_S_AT aldehyde dehydrogenase 1 family, member B1 hs
HG-U133_PLUS_2:209645_S_AT aldehyde dehydrogenase 1 family, member B1 hs
HG-U133A:209645_S_AT aldehyde dehydrogenase 1 family, member B1 hs
HG-U95AV2:38503_AT aldehyde dehydrogenase 1 family, member B1 hs
HG-U95E:78124_AT aldehyde dehydrogenase 1 family, member B1 hs
MG-U74BV2:106594_AT aldehyde dehydrogenase 1 family, member B1 mm
MOE430A:1451260_AT aldehyde dehydrogenase 1 family, member B1 mm
MOUSE430A_2:1451260_AT aldehyde dehydrogenase 1 family, member B1 mm
MOUSE430_2:1451260_AT aldehyde dehydrogenase 1 family, member B1 mm
MU19KSUBB:TC28931_AT Aldehyde dehydrogenase 1 family, member B1 (Aldh1b1), mRNA mm
MU19KSUBB:TC28931_G_AT Aldehyde dehydrogenase 1 family, member B1 (Aldh1b1), mRNA mm
MU19KSUBC:TC37026_AT Aldehyde dehydrogenase 1 family, member B1 (Aldh1b1), mRNA mm
RG-U34B:RC_AA997683_AT aldehyde dehydrogenase 1 family, member B1 (predicted) rn
RAE230B:1383472_AT aldehyde dehydrogenase 1 family, member B1 (predicted) rn
RAT230_2:1383472_AT aldehyde dehydrogenase 1 family, member B1 (predicted) rn
RG-U34B:RC_AI008597_AT Aldehyde dehydrogenase 1 family, member B1 (predicted) rn
YEAST_2:1776624_AT Mitochondrial aldehyde dehydrogenase, required for growth on ethanol and conversion of acetaldehyde to acetate; activity is K+ dependent; utilizes NADP+ or NAD+ equally as coenzymes; expression is glucose repressed Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
8152 metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
16491 oxidoreductase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAC78174 Aldehyde dehydrogenase protein 2 [Caenorhabditis elegans] ref|NP_503467.1| ALdehyde deHydrogenase family member (alh-2) [Caenorhabditis elegans] 0.0
blast AAA20615 Aldehyde dehydrogenase protein 1, isoform a [Caenorhabditis elegans] ref|NP_498081.2| ALdehyde deHydrogenase family member (alh-1) [Caenorhabditis elegans] 0.0
blast CAE75088 Hypothetical protein CBG23008 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR002086 EMBL-EBI Aldehyde dehydrogenase 1.0E-126
Pfam IPR002086 EMBL-EBI Aldehyde dehydrogenase 1.0E-126
Pfam IPR000494 EMBL-EBI Epidermal growth-factor receptor (EGFR), L domain 2.0E-39
Pfam IPR000494 EMBL-EBI Epidermal growth-factor receptor (EGFR), L domain 5.0E-11
Pfam IPR002086 EMBL-EBI Aldehyde dehydrogenase 5.7E-101
Pfam IPR002086 EMBL-EBI Aldehyde dehydrogenase 1.0E-126
Sequence
Target Sequence 
>C. ELEGANS:190712_AT
gacagtgttgctctgcaggatcgagaacttttgtggagggaaaaatctacgatgagtttg
tggcaaaggcaaaggaactggtagagaaaactgtcatcggagacccattcgacgagaaca
ctacacaaggtccgcaaattgatgaatcacaagttgagactattatgaagtatattgagt
ctggaaagaaggagggggctcagctagtgactggcggagttaaacacggagaccagggat
attttgtgaagcctaccatctttgcaaatgtgaatgatcaaatgaaaatcgcacaggaag
agattttcgggccagtcatgattgtcatcagatttgattcgatggaggagttgattgaaa
aagccaataatacaatttatggactggctgctggagtggtgaccaatgatttgaataaag
ctcttcaagtcgcaaatactatccgcgcgggatcagtttgggtcaactgttatgatgttt
ttgatcctgctgctccgtttggaggattcaaacaatctggtatcggtcgtgaacttgggg
agtacggtcttgcggcgtatact

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GACAGTGTTGCTCTGCAGGATCGAG 540 369 1019 Antisense
CTGTCATCGGAGACCCATTCGACGA 364 237 1109 Antisense
GAGAACACTACACAAGGTCCGCAAA 141 391 1132 Antisense
GGCTCAGCTAGTGACTGGCGGAGTT 623 537 1215 Antisense
TTGTGAAGCCTACCATCTTTGCAAA 194 709 1262 Antisense
TTTCGGGCCAGTCATGATTGTCATC 113 671 1323 Antisense
GACTGGCTGCTGGAGTGGTGACCAA 654 375 1400 Antisense
GTCGCAAATACTATCCGCGCGGGAT 15 471 1447 Antisense
TATGATGTTTTTGATCCTGCTGCTC 40 657 1489 Antisense
GGTATCGGTCGTGAACTTGGGGAGT 6 495 1537 Antisense
GGAGTACGGTCTTGCGGCGTATACT 606 517 1557 Antisense
Sequence Source Affymetrix Proprietary Database