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[190701_s_at] fructose-bisphosphatase

Description K07A3.1 /REP_DB=WormBase Gene ID /WP=CE21023 /TR=Q9N2M2 /GB=AAF39910.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=fructose-bisphosphatase
Cluster 6grp_highest_10_10 > 14      6grp_high1_10_10 > 31      4grp_highest_8_8 > 41      4grp_high_8_8 > 50      6grp_highest_nonorm > 25      6grp_total > 32      4grp_total > 61      6grp_cgc > 81      6grp_high1_sub > 03      6grp_cgc_sub > 03      6grp_total_sub > Hat      6grp_rule_based > S3      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 4582
1 2 3 4 range
A 6976
(3)
P 		5583.6
(1)
P 		5085.5
(0.3)
P 		2793.3
(-3)
P 		4183
B 6374.7
(3)
P 		5357.7
(1.2)
P 		5410.5
(1.3)
P 		3029.2
(-3)
P 		3346
C 7008.4
(3)
P 		5329.9
(0.8)
P 		5628.6
(1.2)
P 		2426.6
(-3)
P 		4582
avr 6786.4
(3) 		5423.7
(1) 		5374.9
(0.9) 		2749.7
(-3) 		4037

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 3840
1 2 3 4 5 6 range
A 3620
(-1.2)
P 		5457.1
(3)
P 		4582.3
(1)
P 		4293.9
(0.3)
P 		2947.6
(-2.8)
P 		2842.8
(-3)
P 		2614
B 3875.1
(0.3)
P 		4291.5
(1.1)
P 		5254.4
(3)
P 		3746.6
(0)
P 		3632.8
(-0.2)
P 		2229.1
(-3)
P 		3025
C 5595.8
(2.1)
P 		3634.3
(-1.6)
P 		6069
(3)
P 		3402.8
(-2)
P 		3931.8
(-1)
P 		2864.3
(-3)
P 		3205
avr 4363.6
(0.9) 		4461
(1.1) 		5301.9
(3) 		3814.4
(-0.4) 		3504.1
(-1.1) 		2645.4
(-3) 		2657
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2131
1 2 3 4 range
A 2540
(3)
P 		1212
(-0.7)
P 		1329.4
(-0.4)
P 		408.9
(-3)
P 		2131
B 2032.8
(3)
P 		1323.2
(-0.1)
P 		1253.7
(-0.4)
P 		645.5
(-3)
P 		1387
C 2320
(3)
P 		1532.4
(0.5)
P 		1961.7
(1.9)
P 		409.2
(-3)
P 		1911
avr 2297.6
(3) 		1355.9
(-0.1) 		1514.9
(0.4) 		487.9
(-3) 		1810

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1407
1 2 3 4 5 6 range
A 667.3
(-3)
P 		1940.8
(3)
P 		997.9
(-1.4)
P 		1089
(-1)
P 		889.5
(-2)
P 		692.1
(-2.9)
P 		1274
B 1348.3
(1.8)
P 		1428.4
(2.6)
P 		1275.9
(1.1)
P 		992.3
(-1.5)
P 		1476
(3)
P 		831.2
(-3)
P 		645
C 2074.1
(3)
P 		1108.9
(-1.2)
P 		1544.7
(0.7)
P 		684.3
(-3)
P 		1272.3
(-0.5)
P 		958.8
(-1.8)
P 		1390
avr 1363.2
(1.8) 		1492.7
(3) 		1272.8
(1) 		921.9
(-2.1) 		1212.6
(0.5) 		827.4
(-3) 		665
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 190701_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.322
Sequence Type Exemplar sequence
Representative Public ID K07A3.1 NCBI
Target Description K07A3.1 /REP_DB=WormBase Gene ID /WP=CE21023 /TR=Q9N2M2 /GB=AAF39910.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=fructose-bisphosphatase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_058603(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_058603 NCBI Caenorhabditis elegans K07A3.1 (fructose-bisphosphatase) mRNA, complete cds. 11/11 None
SNAP00000015257 ENSEMBL cdna:SNAP chromosome:CEL140:I:2581204:2586123:-1 11/11 None
GENEFINDER00000015262 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:2581204:2586123:-1 11/11 None
K07A3.1.1 ENSEMBL cdna:known chromosome:CEL140:I:2580942:2586125:-1 gene:K07A3.1 11/11 None
K07A3.1.2 ENSEMBL cdna:known chromosome:CEL140:I:2580942:2586127:-1 gene:K07A3.1 11/11 None
K07A3.1.3 ENSEMBL cdna:known chromosome:CEL140:I:2581016:2586127:-1 gene:K07A3.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:2581203-2586123(-) 100.0 100.0
Public Domain and Genome References
Gene Title fructose-bisphosphatase
Gene Symbol fbp-1
Ensembl K07A3.1
Entrez Gene 266822 Entrez gene
SwissProt Q9N2M2 EMBL-EBI
WormBase CE21023 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:260837_AT fructose-1,6-bisphosphatase, putative / D-fructose-1,6-bisphosphate 1-phosphohydrolase, putative / FBPase, putative at
CANINE:1584815_AT similar to fructose-1,6-bisphosphatase 1 cfa
CANINE_2:CFA.17541.1.S1_S_AT similar to fructose-1,6-bisphosphatase 1 cfa
CANINE_2:CFA.6369.1.A1_AT similar to fructose-1,6-bisphosphatase 1 cfa
CANINE_2:CFAAFFX.2850.1.S1_S_AT similar to fructose-1,6-bisphosphatase 1 cfa
DROSOPHILA_2:1641066_S_AT fructose-1,6-bisphosphatase dm
DROSGENOME1:151797_AT fructose-1,6-bisphosphatase dm
CHICKEN:GGA.5139.1.S1_AT fructose-1,6-bisphosphatase 1 gga
HG-U133_PLUS_2:209696_AT fructose-1,6-bisphosphatase 1 hs
HG-U133A:209696_AT fructose-1,6-bisphosphatase 1 hs
HG-FOCUS:209696_AT fructose-1,6-bisphosphatase 1 hs
HG-U133A_2:209696_AT fructose-1,6-bisphosphatase 1 hs
HUGENEFL:U21931_AT fructose-1,6-bisphosphatase 1 hs
U133_X3P:G439225_3P_AT fructose-1,6-bisphosphatase 1 hs
HG-U95AV2:36495_AT fructose-1,6-bisphosphatase 1 hs
MU11KSUBA:AA276043_S_AT fructose bisphosphatase 1 mm
MU11KSUBB:MSA.23975.0_S_AT fructose bisphosphatase 1 mm
MG-U74AV2:96918_AT fructose bisphosphatase 1 mm
MOE430A:1448470_AT fructose bisphosphatase 1 mm
MOUSE430A_2:1448470_AT fructose bisphosphatase 1 mm
MOUSE430_2:1448470_AT fructose bisphosphatase 1 mm
MU11KSUBB:MSA.32472.0_F_AT Fructose bisphosphatase 1, mRNA (cDNA clone MGC:18799 IMAGE:4194764) mm
MU11KSUBB:MSA.6527.0_AT Fructose bisphosphatase 1, mRNA (cDNA clone MGC:18799 IMAGE:4194764) mm
MU19KSUBB:TC30790_AT Fructose bisphosphatase 1, mRNA (cDNA clone MGC:18799 IMAGE:4194764) mm
RG-U34A:M86240_AT fructose-1,6- biphosphatase 1 rn
RAE230A:1368077_AT fructose-1,6- biphosphatase 1 rn
RAT230_2:1368077_AT fructose-1,6- biphosphatase 1 rn
YEAST_2:1776768_AT Fructose-1,6-bisphosphatase, key regulatory enzyme in the gluconeogenesis pathway, required for glucose metabolism Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
5975 carbohydrate metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
42578 phosphoric ester hydrolase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAF39910 Fructose-1,6-biphosphatase protein 1 [Caenorhabditis elegans] ref|NP_491004.1| K07A3.1 [Caenorhabditis elegans] emb|CAB69047.1| fructose-1,6-bisphosphatase [Caenorhabditis elegans] 0.0
blast CAE60538 Hypothetical protein CBG04165 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR000146 EMBL-EBI Inositol phosphatase/fructose-1,6-bisphosphatase 1.0E-126
Pfam IPR000146 EMBL-EBI Inositol phosphatase/fructose-1,6-bisphosphatase 8.3E-12
Pfam IPR000146 EMBL-EBI Inositol phosphatase/fructose-1,6-bisphosphatase 1.0E-126
Sequence
Target Sequence 
>C. ELEGANS:190701_S_AT
cgtctcaatcggaaccatcttcggaatctacaaaaaacgtggagatggtccggcgactgt
cgatgatgttctgaagcctggaaaggaaatggtggcagctggttatgctctctatggatc
tgctactatggtcgttttgtccactggtgatggtgtcaatgggttcactcttgacccttc
catcggagagttcatcctaacccacccaaatatgaaatgcaaggaaaagggttcaatcta
ctcgctaaacgaaggatatgctcagacatggagcaagggtttcgccgagtatattcgtac
acgaaagtatccagaagccggcaaaaaggcaatgggacagagatatgtcgggtcgatggt
tgccgatgttcatcgtacaattctcaacggaggaatctttctctatccaccaactgtatc
ggctccaaatggaaagctccgcttgttgtacgagtg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CGTCTCAATCGGAACCATCTTCGGA 139 247 414 Antisense
AACGTGGAGATGGTCCGGCGACTGT 346 143 449 Antisense
CGGCGACTGTCGATGATGTTCTGAA 108 243 464 Antisense
GTTATGCTCTCTATGGATCTGCTAC 592 445 515 Antisense
GATCTGCTACTATGGTCGTTTTGTC 698 417 530 Antisense
CATCGGAGAGTTCATCCTAACCCAC 200 213 594 Antisense
GAAAAGGGTTCAATCTACTCGCTAA 246 353 637 Antisense
GACATGGAGCAAGGGTTTCGCCGAG 553 367 678 Antisense
ACGGAGGAATCTTTCTCTATCCACC 157 97 800 Antisense
TCTCTATCCACCAACTGTATCGGCT 320 613 813 Antisense
GAAAGCTCCGCTTGTTGTACGAGTG 692 359 845 Antisense
Sequence Source Affymetrix Proprietary Database