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[190687_s_at] casein kinase /// serine/threonine kinase

Description Y38H8A.3 /REP_DB=WormBase Gene ID /WP=CE18365 /TR=O62426 /GB=CAA16345.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster 6grp_high1_10_10 > 88      6grp_total > 88      4grp_total > 05      6grp_high1_sub > Da      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 83
1 2 3 4 range
A 75.8
(0.6)
P 		34.2
(-3)
A 		60.8
(-0.7)
P 		103.2
(3)
A 		69
B 70.4
(-1.2)
P 		69.6
(-1.3)
A 		60.5
(-3)
A 		93.4
(3)
P 		33
C 50.9
(-2.2)
P 		40.3
(-3)
A 		52.1
(-2.1)
P 		117.2
(3)
P 		77
avr 65.7
(-1.1) 		48
(-3) 		57.8
(-2) 		104.6
(3) 		57

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1277
1 2 3 4 5 6 range
A 10.7
(-3)
A 		23.4
(-2.9)
A 		66.2
(-2.7)
P 		146.4
(-2.3)
P 		714.5
(0.4)
P 		1259
(3)
P 		1248
B 34.1
(-3)
A 		53.1
(-2.9)
P 		77.2
(-2.8)
P 		129.4
(-2.5)
P 		811.6
(1)
P 		1199.9
(3)
P 		1166
C 61.2
(-3)
P 		106.7
(-2.8)
P 		88
(-2.9)
P 		171
(-2.5)
P 		789
(0.6)
P 		1287.3
(3)
P 		1226
avr 35.3
(-3) 		61.1
(-2.9) 		77.1
(-2.8) 		148.9
(-2.4) 		771.7
(0.6) 		1248.7
(3) 		1213
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 20
1 2 3 4 range
A 27.6
(3)
P 		7.4
(-3)
A 		15.9
(-0.5)
P 		15.1
(-0.7)
A 		20
B 22.4
(3)
P 		17.2
(-0.7)
A 		14
(-3)
A 		19.9
(1.2)
P 		8
C 16.8
(0.8)
P 		11.6
(-3)
A 		18.2
(1.8)
P 		19.8
(3)
P 		8
avr 22.3
(3) 		12.1
(-3) 		16
(-0.7) 		18.3
(0.6) 		10

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 445
1 2 3 4 5 6 range
A 2
(-3)
A 		8.3
(-2.9)
A 		14.4
(-2.8)
P 		37.1
(-2.3)
P 		215.6
(1.2)
P 		306.5
(3)
P 		305
B 11.9
(-3)
A 		17.7
(-2.9)
P 		18.8
(-2.9)
P 		34.3
(-2.7)
P 		329.7
(1.4)
P 		447.4
(3)
P 		436
C 22.7
(-3)
P 		32.5
(-2.9)
P 		22.4
(-3)
P 		34.4
(-2.8)
P 		255.3
(0.4)
P 		430.9
(3)
P 		409
avr 12.2
(-3) 		19.5
(-2.9) 		18.5
(-2.9) 		35.3
(-2.6) 		266.9
(1) 		394.9
(3) 		383
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 190687_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.8676
Sequence Type Exemplar sequence
Representative Public ID Y38H8A.3 NCBI
Target Description Y38H8A.3 /REP_DB=WormBase Gene ID /WP=CE18365 /TR=O62426 /GB=CAA16345.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_068436(11), NM_070195(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_068436 NCBI Caenorhabditis elegans C39H7.1 (C39H7.1) mRNA, complete cds. 11/11 A 
NM_070195 NCBI Caenorhabditis elegans Y38H8A.3 (Y38H8A.3) mRNA, complete cds. 11/11 A 
SNAP00000011904 ENSEMBL cdna:SNAP chromosome:CEL140:IV:13472541:13473904:1 11/11 None
GENEFINDER00000011912 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:13472541:13473904:1 11/11 None
SNAP00000020750 ENSEMBL cdna:SNAP chromosome:CEL140:IV:5631966:5633306:1 11/11 None
GENEFINDER00000020757 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:5631966:5633306:1 11/11 None
C39H7.1 ENSEMBL cdna:known chromosome:CEL140:IV:5631916:5633306:1 gene:C39H7.1 11/11 A 
Y38H8A.3 ENSEMBL cdna:known chromosome:CEL140:IV:13472541:13473948:1 gene:Y38H8A.3 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:13472546-13473910(+) 100.0 100.0
chrIV:5631971-5633312(+) 92.13 92.13
Public Domain and Genome References
Gene Title casein kinase
serine/threonine kinase
Ensembl C39H7.1
Y38H8A.3
Entrez Gene 177341 Entrez gene
178315 Entrez gene
SwissProt Q18553 EMBL-EBI
O62426 EMBL-EBI
WormBase CE06942 Wormbase
CE18365 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB00674 Hypothetical protein C39H7.1 [Caenorhabditis elegans] ref|NP_500837.1| C39H7.1 [Caenorhabditis elegans] 0.0
blast CAA16345 Hypothetical protein Y38H8A.3 [Caenorhabditis elegans] ref|NP_502596.1| Y38H8A.3 [Caenorhabditis elegans] 0.0
blast CAA16345 Hypothetical protein Y38H8A.3 [Caenorhabditis elegans] ref|NP_502596.1| Y38H8A.3 [Caenorhabditis elegans] 1.0E-180
blast AAB00674 Hypothetical protein C39H7.1 [Caenorhabditis elegans] ref|NP_500837.1| C39H7.1 [Caenorhabditis elegans] 1.0E-180
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 2.5E-5
Pfam IPR000719 EMBL-EBI Protein kinase 1.3E-4
Pfam IPR000719 EMBL-EBI Protein kinase 5.4E-10
Sequence
Target Sequence 
>C. ELEGANS:190687_S_AT
atgtcgatgggttgctcgattggaataggcattcaatctctggaggcactggaggatctt
cacaacattggttacctccatcgtgacgtcaaacccggaaactacacgattggacgtccc
gagctgaacgagatccgcaaggtgtacattttggattttggaatgtgcagaaagttcact
ggaaatgatggaaccattagaaagccacgccaagctgctggtttccggggaactgtcaaa
tacgctccaatcagttgccatcttcagagagaactttgccgcaaggacgacttggagact
tggatgtacatgcaggtcgaattgtcgcacggaacaattccttggcaatatatttccgat
atgaaccaagttggacaggccaagcaagcgatccgcaacaatctgggctccctgttccca
ccgccatgcccacatcaattccaggacatcatgcgtatggttgatgcaatgaaatactat
gatgcacccaactatcaagcaatctacggaatgatgcgtcaagcttatggtgcatgtgga
tccaacgagaatgctccgtacgattgggaaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATGTCGATGGGTTGCTCGATTGGAA 468 49 337 Antisense
GAACCATTAGAAAGCCACGCCAAGC 612 343 527 Antisense
ATTAGAAAGCCACGCCAAGCTGCTG 709 7 532 Antisense
TCCAATCAGTTGCCATCTTCAGAGA 338 587 582 Antisense
GCCATCTTCAGAGAGAACTTTGCCG 448 279 593 Antisense
GAACTTTGCCGCAAGGACGACTTGG 14 351 607 Antisense
GAAATACTATGATGCACCCAACTAT 435 361 807 Antisense
ATGATGCACCCAACTATCAAGCAAT 205 47 815 Antisense
GAATGATGCGTCAAGCTTATGGTGC 504 331 845 Antisense
GGATCCAACGAGAATGCTCCGTACG 297 513 874 Antisense
GAGAATGCTCCGTACGATTGGGAAA 179 391 883 Antisense
Sequence Source Affymetrix Proprietary Database