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[190686_at] serine/threonine kinase

Description Y38H8A.3 /REP_DB=WormBase Gene ID /WP=CE18365 /TR=O62426 /GB=CAA16345.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster 6grp_total > 98      4grp_total > 13      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 47
1 2 3 4 range
A 7.4
(-3)
A 		10.8
(3)
A 		8.3
(-1.4)
A 		8.3
(-1.4)
A 		3
B 15.9
(3)
A 		4.6
(-2.1)
A 		2.7
(-3)
A 		10
(0.3)
A 		13
C 18.1
(-1.3)
A 		5.7
(-3)
A 		7.9
(-2.7)
A 		49.4
(3)
A 		44
avr 13.8
(-0.2) 		7
(-2.7) 		6.3
(-3) 		22.6
(3) 		16

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 335
1 2 3 4 5 6 range
A 9.2
(-3)
A 		16
(-2.9)
A 		10.3
(-3)
A 		14.5
(-2.9)
A 		184.3
(0.3)
P 		331.2
(3)
P 		322
B 8.6
(-3)
A 		7.5
(-3)
A 		38.3
(-2.2)
A 		13.6
(-2.8)
A 		213.6
(2.3)
P 		241.5
(3)
P 		234
C 22.5
(-2.8)
A 		36.4
(-2.6)
A 		13.7
(-3)
A 		54.3
(-2.3)
A 		189.8
(0.2)
P 		342.2
(3)
P 		329
avr 13.4
(-3) 		20
(-2.9) 		20.8
(-2.8) 		27.5
(-2.7) 		195.9
(0.8) 		305
(3) 		292
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 8
1 2 3 4 range
A 2.7
(3)
A 		2.4
(1.8)
A 		2.2
(1)
A 		1.2
(-3)
A 		2
B 5.1
(3)
A 		1.1
(-2.3)
A 		0.6
(-3)
A 		2.1
(-1)
A 		5
C 6
(0.9)
A 		1.7
(-3)
A 		2.8
(-2)
A 		8.3
(3)
A 		7
avr 4.6
(3) 		1.7
(-3) 		1.9
(-2.6) 		3.9
(1.6) 		3

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 113
1 2 3 4 5 6 range
A 1.7
(-3)
A 		5.7
(-2.7)
A 		2.2
(-3)
A 		3.7
(-2.8)
A 		55.6
(1.1)
P 		80.6
(3)
P 		79
B 3
(-3)
A 		2.5
(-3)
A 		9.3
(-2.5)
A 		3.6
(-2.9)
A 		86.8
(2.8)
P 		90.1
(3)
P 		88
C 8.3
(-2.7)
A 		11.1
(-2.6)
A 		3.5
(-3)
A 		10.9
(-2.6)
A 		61.4
(0.1)
P 		114.6
(3)
P 		111
avr 4.3
(-3) 		6.4
(-2.9) 		5
(-3) 		6.1
(-2.9) 		67.9
(1.2) 		95.1
(3) 		91
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190686_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.8676
Sequence Type Exemplar sequence
Representative Public ID Y38H8A.3 NCBI
Target Description Y38H8A.3 /REP_DB=WormBase Gene ID /WP=CE18365 /TR=O62426 /GB=CAA16345.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_070195(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_070195 NCBI Caenorhabditis elegans Y38H8A.3 (Y38H8A.3) mRNA, complete cds. 11/11 A 
SNAP00000011904 ENSEMBL cdna:SNAP chromosome:CEL140:IV:13472541:13473904:1 11/11 None
GENEFINDER00000011912 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:13472541:13473904:1 11/11 None
Y38H8A.3 ENSEMBL cdna:known chromosome:CEL140:IV:13472541:13473948:1 gene:Y38H8A.3 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:13472546-13473910(+) 100.0 100.0
chrIV:5631971-5633312(+) 92.13 92.13
Public Domain and Genome References
Gene Title serine/threonine kinase
Ensembl Y38H8A.3
Entrez Gene 178315 Entrez gene
SwissProt O62426 EMBL-EBI
WormBase CE18365 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA16345 Hypothetical protein Y38H8A.3 [Caenorhabditis elegans] ref|NP_502596.1| Y38H8A.3 [Caenorhabditis elegans] 0.0
blast AAB00674 Hypothetical protein C39H7.1 [Caenorhabditis elegans] ref|NP_500837.1| C39H7.1 [Caenorhabditis elegans] 1.0E-180
blast CAE67138 Hypothetical protein CBG12561 [Caenorhabditis briggsae] 1.0E-174
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 5.4E-10
Sequence
Target Sequence 
>C. ELEGANS:190686_AT
aagcaggtgtcggtggccatatgtcgatgggttgctcgattggaataggcattcaatctc
tggaggcactggaggatcttcacaacattggttacctccatcgtgacgtcaaacccggaa
actacacgattggacgtcccgagctgaacgagatccgcaaggtgtacattttggattttg
gaatgtgcagaaagttcactggaaatgatggaaccattagaaagccacgccaagctgctg
gtttccggggaactgtcaaatacgctccaatcagttgccatcttcagagagaactttgcc
gcaaggacgacttggagacttggatgtacatgcaggtcgaattgtcgcacggaacaattc
cttggcaatatatttccgatatgaaccaagttggacaggccaagcaagcgatccgcaaca
atctgggctccctgttcccaccgccatgcccacatcaattccaggacatcatgcgtatgg
ttgatgcaatgaaatactatgatgcacccaactatcaagcaatctacggaatgatgcgtc
aagcttatggtgcatgtggatccaacg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAGCAGGTGTCGGTGGCCATATGTC 606 151 317 Antisense
ATAGGCATTCAATCTCTGGAGGCAC 507 21 361 Antisense
GGCACTGGAGGATCTTCACAACATT 345 535 381 Antisense
ACAACATTGGTTACCTCCATCGTGA 130 113 398 Antisense
TCCCGAGCTGAACGAGATCCGCAAG 431 597 453 Antisense
GAGATCCGCAAGGTGTACATTTTGG 487 395 466 Antisense
CTGCTGGTTTCCGGGGAACTGTCAA 418 237 551 Antisense
GGGGAACTGTCAAATACGCTCCAAT 447 497 563 Antisense
GCAGGTCGAATTGTCGCACGGAACA 215 311 648 Antisense
ATGCCCACATCAATTCCAGGACATC 62 43 762 Antisense
GCTTATGGTGCATGTGGATCCAACG 448 305 859 Antisense
Sequence Source Affymetrix Proprietary Database