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[190685_at] serine/threonine kinase

Description C04A11.3 /REP_DB=WormBase Gene ID /WP=CE07905 /TR=O17566 /GB=CAB03829.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster 6grp_total > 48      4grp_total > 06      6grp_cgc > 18      6grp_cgc_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 61
1 2 3 4 range
A 19.1
(1.7)
A 		6.5
(-3)
A 		22.7
(3)
A 		10.3
(-1.6)
A 		16
B 18
(2.6)
A 		3.1
(-2.9)
A 		2.8
(-3)
A 		19
(3)
A 		16
C 11.2
(-2.3)
A 		3.8
(-3)
A 		12.5
(-2.1)
A 		64
(3)
P 		60
avr 16.1
(-0.4) 		4.5
(-3) 		12.7
(-1.2) 		31.1
(3) 		27

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 35
1 2 3 4 5 6 range
A 29.1
(3)
A 		20.6
(1.1)
A 		21
(1.2)
A 		1.9
(-3)
A 		7.5
(-1.8)
A 		16.4
(0.2)
A 		27
B 20
(-0.1)
A 		8.4
(-2.5)
A 		5.8
(-3)
A 		30.1
(1.9)
A 		24.5
(0.8)
A 		35.5
(3)
P 		30
C 24
(0.8)
A 		36.8
(3)
A 		4.7
(-2.5)
A 		2
(-3)
A 		17.5
(-0.3)
A 		31
(2)
P 		35
avr 24.4
(1.9) 		21.9
(1) 		10.5
(-3) 		11.3
(-2.7) 		16.5
(-0.9) 		27.6
(3) 		17
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 10
1 2 3 4 range
A 7
(3)
A 		1.4
(-3)
A 		5.9
(1.8)
A 		1.5
(-2.9)
A 		6
B 5.7
(3)
A 		0.8
(-2.8)
A 		0.6
(-3)
A 		4
(1)
A 		5
C 3.7
(-1.4)
A 		1.1
(-3)
A 		4.4
(-1)
A 		10.8
(3)
P 		10
avr 5.5
(3) 		1.1
(-3) 		3.6
(0.4) 		5.4
(2.9) 		4

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 13
1 2 3 4 5 6 range
A 5.4
(1.3)
A 		7.3
(3)
A 		4.6
(0.6)
A 		0.5
(-3)
A 		2.3
(-1.4)
A 		4
(0.1)
A 		7
B 7
(-0.2)
A 		2.8
(-2.3)
A 		1.4
(-3)
A 		8
(0.4)
A 		9.9
(1.3)
A 		13.2
(3)
P 		12
C 8.9
(1.7)
A 		11.2
(3)
A 		1.2
(-2.6)
A 		0.4
(-3)
A 		5.7
(-0.1)
A 		10.4
(2.6)
P 		11
avr 7.1
(1.1) 		7.1
(1.1) 		2.4
(-3) 		3
(-2.5) 		6
(0.2) 		9.2
(3) 		7
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190685_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.17561
Sequence Type Exemplar sequence
Representative Public ID C04A11.3 NCBI
Target Description C04A11.3 /REP_DB=WormBase Gene ID /WP=CE07905 /TR=O17566 /GB=CAB03829.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_077889(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_077889 NCBI Caenorhabditis elegans C04A11.3 (C04A11.3) mRNA, complete cds. 11/11 None
SNAP00000007390 ENSEMBL cdna:SNAP chromosome:CEL140:X:13677179:13681997:1 11/11 None
GENEFINDER00000007397 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:13677179:13681997:1 11/11 None
C04A11.3 ENSEMBL cdna:known chromosome:CEL140:X:13677179:13681997:1 gene:C04A11.3 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:13677178-13681997(+) 100.0 100.0
Public Domain and Genome References
Gene Title serine/threonine kinase
Gene Symbol tag-334
Ensembl C04A11.3
Entrez Gene 181488 Entrez gene
SwissProt O17566 EMBL-EBI
WormBase CE07905 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFA.21222.1.A1_S_AT similar to Serine/threonine-protein kinase 10 (Lymphocyte-oriented kinase) cfa
CANINE_2:CFAAFFX.16478.1.S1_S_AT similar to Serine/threonine-protein kinase 10 (Lymphocyte-oriented kinase) cfa
DROSOPHILA_2:1633461_AT Polo kinase kinase 1 dm
DROSOPHILA_2:1623189_AT Polo kinase kinase 1 dm
DROSGENOME1:151762_S_AT Polo kinase kinase 1 dm
DROSGENOME1:143050_AT Polo kinase kinase 1 dm
CHICKEN:GGAAFFX.22528.1.S1_S_AT similar to hSLK gga
HG-U133_PLUS_2:206875_S_AT STE20-like kinase (yeast) hs
HG-U133A:206875_S_AT STE20-like kinase (yeast) hs
HG-U133A_2:206875_S_AT STE20-like kinase (yeast) hs
HU35KSUBA:D86959_AT STE20-like kinase (yeast) hs
HUGENEFL:D86959_AT STE20-like kinase (yeast) hs
HU35KSUBD:RC_AA505137_AT STE20-like kinase (yeast) hs
U133_X3P:G7661993_3P_S_AT STE20-like kinase (yeast) hs
HG-U95D:91586_AT STE20-like kinase (yeast) hs
MOUSE430_2:1425977_A_AT STE20-like kinase (yeast) mm
MOE430A:1425977_A_AT STE20-like kinase (yeast) mm
MOUSE430A_2:1425977_A_AT STE20-like kinase (yeast) mm
MU11KSUBA:AA108677_S_AT STE20-like kinase (yeast) mm
MG-U74AV2:101437_AT STE20-like kinase (yeast) mm
MG-U74AV2:96130_AT STE20-like kinase (yeast) mm
MG-U74BV2:107928_AT STE20-like kinase (yeast) mm
MOE430A:1433999_AT STE20-like kinase (yeast) mm
MOUSE430A_2:1433999_AT STE20-like kinase (yeast) mm
MOUSE430_2:1433999_AT STE20-like kinase (yeast) mm
MOE430A:1419092_A_AT STE20-like kinase (yeast) mm
MOUSE430A_2:1419092_A_AT STE20-like kinase (yeast) mm
MOUSE430_2:1419092_A_AT STE20-like kinase (yeast) mm
MOE430A:1449336_A_AT STE20-like kinase (yeast) mm
MOUSE430A_2:1449336_A_AT STE20-like kinase (yeast) mm
MOUSE430_2:1449336_A_AT STE20-like kinase (yeast) mm
MOE430B:1443815_X_AT STE20-like kinase (yeast) mm
MOUSE430_2:1443815_X_AT STE20-like kinase (yeast) mm
MU19KSUBB:TC28792_AT Ste20-related kinase SMAK (SMAK) mm
MU19KSUBB:TC28842_AT Ste20-related kinase SMAK (SMAK) mm
MU19KSUBB:TC32183_AT Ste20-related kinase SMAK (SMAK) mm
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB03829 Hypothetical protein C04A11.3 [Caenorhabditis elegans] ref|NP_510290.1| C04A11.3 [Caenorhabditis elegans] 0.0
blast CAE63098 Hypothetical protein CBG07389 [Caenorhabditis briggsae] 0.0
blast XP_392064 PREDICTED: similar to GA18234-PA [Apis mellifera] 7.0E-92
Protein Families
Method ID Description E-Value
ec ABL1_HUMAN (P00519) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.1.112) (p150) (c-ABL) 1.0E-169
hanks 2.1.17 CaMK Group; CaMK I Regulated by Ca2+/CaM and close relatives; TWITCH 3.0E-64
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 4.3E-75
Sequence
Target Sequence 
>C. ELEGANS:190685_AT
cttctccgcacacaaatgcttgctagacaccaacgtgaaatggctcaaatcgagaagatt
catcaagaagaggaagacgatctcatcagagcactaacactcgatcgtaaaaagctaccg
aaaatgttgcgctctgagacgaaaactcgtagtgtgatgttcaaagagagcctgcgaatc
agtgcagtgaacatgtcaaacgcggaaatgcaagaacgaattcgacgattcgatgagcaa
gaagcgttgcgcatgagagctgcattggaagatcacgatttgaagtcgcagaagaagttg
caaatattaaaggagcgccaccaggaagcgatcatcgagcttgatgagatgcagaacgag
aagcgcaagcagttgctggaaaaagaaaggaacacgatgaaggagcacgaggcaaagtat
cacgagatgcgtgagctgtggcaggagaatttgattgcaaggaaaacggtgctcgaggag
aagtttgaggacgaactctcaaagcaggaagtgttctacggaatgtcgtacacttcgtct
c

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CTTCTCCGCACACAAATGCTTGCTA 257 221 3124 Antisense
AATGCTTGCTAGACACCAACGTGAA 4 167 3138 Antisense
GGAAGACGATCTCATCAGAGCACTA 522 531 3195 Antisense
ATCAGAGCACTAACACTCGATCGTA 453 27 3208 Antisense
GCTACCGAAAATGTTGCGCTCTGAG 214 303 3237 Antisense
GAGAGCCTGCGAATCAGTGCAGTGA 206 395 3289 Antisense
GAAGCGTTGCGCATGAGAGCTGCAT 346 343 3364 Antisense
GGAGCGCCACCAGGAAGCGATCATC 533 521 3435 Antisense
GGAGCACGAGGCAAAGTATCACGAG 708 519 3525 Antisense
CACGAGATGCGTGAGCTGTGGCAGG 443 199 3544 Antisense
TACGGAATGTCGTACACTTCGTCTC 538 647 3640 Antisense
Sequence Source Affymetrix Proprietary Database