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[190680_s_at] P53-binding protein like

Description F46F3.4 /REP_DB=WormBase Gene ID /WP=CE19874 /TR=Q9XVN3 /GB=CAB03115.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=P53-binding protein like
Cluster 6grp_highest_10_10 > 93      6grp_high1_10_10 > 48      4grp_highest_8_8 > 50      4grp_high_8_8 > 40      6grp_highest_nonorm > 84      6grp_total > 38      4grp_total > 55      6grp_highest_sub > Cu      6grp_cgc > 18      6grp_high1_sub > Cu      6grp_cgc_sub > Cu      6grp_total_sub > Cup      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 527
1 2 3 4 range
A 818.7
(3)
P 		523.1
(-1.2)
P 		597.8
(-0.2)
P 		400.8
(-3)
P 		418
B 927.8
(3)
P 		643.8
(-2.2)
P 		600.7
(-3)
P 		667.1
(-1.8)
P 		327
C 761.6
(3)
P 		587.8
(-2.2)
P 		574.4
(-2.6)
P 		562.7
(-3)
P 		199
avr 836
(3) 		584.9
(-2.2) 		591
(-2) 		543.5
(-3) 		293

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 452
1 2 3 4 5 6 range
A 652.5
(0.5)
P 		793.5
(3)
P 		451.1
(-3)
P 		555.1
(-1.2)
P 		574.1
(-0.8)
P 		733.8
(2)
P 		342
B 634.7
(3)
P 		591.7
(1.9)
P 		403.5
(-3)
P 		563.8
(1.2)
P 		537.3
(0.5)
P 		591.2
(1.9)
P 		231
C 855.5
(3)
P 		635.2
(-0.3)
P 		532.8
(-1.8)
P 		451.8
(-3)
P 		529.3
(-1.8)
P 		762.7
(1.6)
P 		404
avr 714.2
(3) 		673.5
(2) 		462.5
(-3) 		523.6
(-1.5) 		546.9
(-1) 		695.9
(2.6) 		252
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 239
1 2 3 4 range
A 298.1
(3)
P 		113.6
(-1.6)
P 		156.3
(-0.6)
P 		58.7
(-3)
P 		239
B 295.9
(3)
P 		159
(-2.2)
P 		139.2
(-3)
P 		142.2
(-2.9)
P 		157
C 252.1
(3)
P 		169
(-0.2)
P 		200.2
(1)
P 		94.9
(-3)
P 		157
avr 282
(3) 		147.2
(-1.4) 		165.2
(-0.8) 		98.6
(-3) 		183

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 226
1 2 3 4 5 6 range
A 120.3
(-2.3)
P 		282.2
(3)
P 		98.2
(-3)
P 		140.8
(-1.6)
P 		173.2
(-0.6)
P 		178.6
(-0.4)
P 		184
B 220.8
(3)
P 		197
(1.8)
P 		98
(-3)
P 		149.3
(-0.5)
P 		218.3
(2.9)
P 		220.5
(3)
P 		123
C 317.1
(3)
P 		193.8
(-0.3)
P 		135.6
(-1.8)
P 		90.9
(-3)
P 		171.3
(-0.9)
P 		255.3
(1.4)
P 		226
avr 219.4
(2.7) 		224.3
(3) 		110.6
(-3) 		127
(-2.1) 		187.6
(1.1) 		218.1
(2.7) 		114
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 190680_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.13197
Sequence Type Exemplar sequence
Representative Public ID F46F3.4 NCBI
Target Description F46F3.4 /REP_DB=WormBase Gene ID /WP=CE19874 /TR=Q9XVN3 /GB=CAB03115.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=P53-binding protein like
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073554(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073554 NCBI Caenorhabditis elegans APoptosis Enhancer family member (ape-1) (ape-1) mRNA, complete cds. 11/11 None
SNAP00000004393 ENSEMBL cdna:SNAP chromosome:CEL140:V:11684262:11687443:1 11/11 None
GENEFINDER00000004397 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:11684262:11687443:1 11/11 None
F46F3.4 ENSEMBL cdna:known chromosome:CEL140:V:11678531:11687849:1 gene:F46F3.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:11678550-11687443(+) 100.0 100.0
Public Domain and Genome References
Gene Title P53-binding protein like
Gene Symbol ape-1
Ensembl F46F3.4
Entrez Gene 179601 Entrez gene
SwissProt Q9XVN3 EMBL-EBI
WormBase CE19874 Wormbase
Functional Annotations
Ortholog
ID Title Organism
HG-U133_PLUS_2:218849_S_AT protein phosphatase 1, regulatory (inhibitor) subunit 13 like hs
HG-U133A:218849_S_AT protein phosphatase 1, regulatory (inhibitor) subunit 13 like hs
HG-FOCUS:218849_S_AT protein phosphatase 1, regulatory (inhibitor) subunit 13 like hs
HG-U133A_2:218849_S_AT protein phosphatase 1, regulatory (inhibitor) subunit 13 like hs
HU35KSUBA:HUM_ALU_AT protein phosphatase 1, regulatory (inhibitor) subunit 13 like hs
HU35KSUBB:HUM_ALU_AT protein phosphatase 1, regulatory (inhibitor) subunit 13 like hs
HU35KSUBC:HUM_ALU_AT protein phosphatase 1, regulatory (inhibitor) subunit 13 like hs
HU35KSUBD:HUM_ALU_AT protein phosphatase 1, regulatory (inhibitor) subunit 13 like hs
HUGENEFL:HUM_ALU_AT protein phosphatase 1, regulatory (inhibitor) subunit 13 like hs
HC-G110:HUM_ALU_AT protein phosphatase 1, regulatory (inhibitor) subunit 13 like hs
HU35KSUBB:RC_T40767_AT protein phosphatase 1, regulatory (inhibitor) subunit 13 like hs
U133_X3P:G5730000_3P_A_AT protein phosphatase 1, regulatory (inhibitor) subunit 13 like hs
HG-U95B:55079_AT protein phosphatase 1, regulatory (inhibitor) subunit 13 like hs
Protein Similarities
Method ID Description E-Value
blast CAB03115 Hypothetical protein F46F3.4 [Caenorhabditis elegans] ref|NP_505955.1| APoptosis Enhancer family member (ape-1) [Caenorhabditis elegans] sp|Q9XVN3|IASPP_CAEEL Apoptotic enhancer 1 protein (Inhibitor member of the ASPP family) (Protein iASPP) (Ce-iASPP) 0.0
blast CAE75316 Hypothetical protein CBG23287 [Caenorhabditis briggsae] 0.0
blast EAL39784 ENSANGP00000029632 [Anopheles gambiae str. PEST] ref|XP_555930.1| ENSANGP00000029632 [Anopheles gambiae str. PEST] 3.0E-58
Protein Domains
Database ID Description E-Value
Pfam IPR001452 EMBL-EBI SH3 5.9E-15
Pfam IPR002110 EMBL-EBI Ankyrin 8.6E-11
Pfam IPR002110 EMBL-EBI Ankyrin 1.0E-8
Pfam IPR001452 EMBL-EBI SH3 5.9E-15
Pfam IPR002110 EMBL-EBI Ankyrin 8.6E-11
Pfam IPR002110 EMBL-EBI Ankyrin 1.0E-8
Sequence
Target Sequence 
>C. ELEGANS:190680_S_AT
gcagtgcctcaaagctaacagatgtctcacaggccaatgatgaagggattacggcgttgc
acaatgcgatttgtgctggacactatgagattgtaagatttttgatcgagaacgacgctg
atgtgaatgctcaagattccgatggttggactccacttcattgtgcagcttcctgtaata
accttccaatggttagacaacttgtggaaggaggaggatgcgttctcgcttcgacactat
ctgatatggaaacacctgtggagaagtgtgaagaagatgaagatggttatgatggatgtt
tgaagtatctttccgcagcccataactcaacgggatcaattaatactggaaaagtttacg
ctgcttatggatatgaggcggcatttgaagatgagctcagttttgatgcaggagatgaat
tgacggttattgagaaagataaagtcgataaaaattggtggacatgtgagaagaacaatg
gagagaagggacaagtaccaagaacatatttggcgttgtacccatcgttaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GCAGTGCCTCAAAGCTAACAGATGT 402 311 1724 Antisense
AACAGATGTCTCACAGGCCAATGAT 229 137 1740 Antisense
TGATGAAGGGATTACGGCGTTGCAC 406 565 1761 Antisense
GAACGACGCTGATGTGAATGCTCAA 653 347 1833 Antisense
AGATTCCGATGGTTGGACTCCACTT 391 65 1857 Antisense
TTGGACTCCACTTCATTGTGCAGCT 328 709 1869 Antisense
CAGCTTCCTGTAATAACCTTCCAAT 44 197 1889 Antisense
GAAGGAGGAGGATGCGTTCTCGCTT 110 335 1930 Antisense
TTCTCGCTTCGACACTATCTGATAT 318 693 1946 Antisense
TTCCGCAGCCCATAACTCAACGGGA 629 693 2034 Antisense
TATTTGGCGTTGTACCCATCGTTAA 42 661 2230 Antisense
Sequence Source Affymetrix Proprietary Database