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[190671_at] serine/threonine kinase

Description C36B1.10 /REP_DB=WormBase Gene ID /WP=CE05377 /TR=Q93344 /GB=CAB02275.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster 6grp_total > 97      4grp_total > 02      6grp_total_sub > Increase      6grp_rule_based > S6      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 155
1 2 3 4 range
A 2.7
(-3)
A 		3.4
(-3)
A 		2.9
(-3)
A 		153.8
(3)
P 		151
B 22.8
(0.4)
A 		4.2
(-2.7)
A 		2.7
(-3)
A 		38.5
(3)
A 		36
C 3.4
(-3)
A 		3.5
(-3)
A 		3.8
(-3)
A 		157.9
(3)
P 		155
avr 9.6
(-2.7) 		3.7
(-3) 		3.1
(-3) 		116.7
(3) 		114

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 386
1 2 3 4 5 6 range
A 2.6
(-3)
A 		2.8
(-3)
A 		48.5
(-2.3)
A 		53.6
(-2.2)
A 		227.8
(0.5)
P 		387.6
(3)
P 		385
B 4
(-3)
A 		7.2
(-2.9)
A 		3.5
(-3)
A 		53.5
(-2.2)
A 		264.1
(1.2)
P 		378.2
(3)
P 		375
C 2.1
(-3)
A 		16.3
(-2.7)
A 		5.3
(-2.9)
A 		42.7
(-2.3)
A 		188.2
(0.3)
P 		339.8
(3)
P 		338
avr 2.9
(-3) 		8.8
(-2.9) 		19.1
(-2.7) 		49.9
(-2.2) 		226.7
(0.7) 		368.5
(3) 		366
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 26
1 2 3 4 range
A 1
(-2.9)
A 		0.7
(-3)
A 		0.8
(-3)
A 		22.5
(3)
P 		22
B 7.3
(2.3)
A 		1
(-2.7)
A 		0.6
(-3)
A 		8.2
(3)
A 		8
C 1.1
(-3)
A 		1
(-3)
A 		1.3
(-2.9)
A 		26.6
(3)
P 		26
avr 3.1
(-2.3) 		0.9
(-3) 		0.9
(-3) 		19.1
(3) 		18

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 141
1 2 3 4 5 6 range
A 0.5
(-3)
A 		1
(-3)
A 		10.6
(-2.4)
A 		13.6
(-2.2)
A 		68.7
(1.4)
P 		94.4
(3)
P 		94
B 1.4
(-3)
A 		2.4
(-2.9)
A 		0.8
(-3)
A 		14.2
(-2.4)
A 		107.3
(1.6)
P 		141
(3)
P 		140
C 0.8
(-3)
A 		5
(-2.8)
A 		1.4
(-3)
A 		8.6
(-2.6)
A 		60.9
(0.2)
P 		113.8
(3)
P 		113
avr 0.9
(-3) 		2.8
(-2.9) 		4.3
(-2.8) 		12.1
(-2.4) 		79
(1.1) 		116.4
(3) 		116
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190671_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.372
Sequence Type Exemplar sequence
Representative Public ID C36B1.10 NCBI
Target Description C36B1.10 /REP_DB=WormBase Gene ID /WP=CE05377 /TR=Q93344 /GB=CAB02275.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059966(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_059966 NCBI Caenorhabditis elegans C36B1.10 (C36B1.10) mRNA, complete cds. 11/11 None
SNAP00000022506 ENSEMBL cdna:SNAP chromosome:CEL140:I:8757793:8759422:-1 11/11 None
GENEFINDER00000022515 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:8757793:8759422:-1 11/11 None
C36B1.10 ENSEMBL cdna:known chromosome:CEL140:I:8757791:8759422:-1 gene:C36B1.10 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:8757723-8759353(-) 100.0 100.0
Public Domain and Genome References
Gene Title serine/threonine kinase
Ensembl C36B1.10
Entrez Gene 172683 Entrez gene
SwissProt Q93344 EMBL-EBI
WormBase CE05377 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB02275 Hypothetical protein C36B1.10 [Caenorhabditis elegans] ref|NP_492367.1| C36B1.10 [Caenorhabditis elegans] 0.0
blast CAB76409 Hypothetical protein Y106G6E.1 [Caenorhabditis elegans] emb|CAB76732.1| Hypothetical protein Y106G6E.1 [Caenorhabditis elegans] ref|NP_492689.1| Y106G6E.1 [Caenorhabditis elegans] 1.0E-175
blast CAE60578 Hypothetical protein CBG04212 [Caenorhabditis briggsae] 1.0E-140
Protein Families
Method ID Description E-Value
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 9.0E-53
hanks 3.1.5 CMCG Group; CMGC I Cyclin-dependent (CDKs) and close relatives; Cdk6 5.0E-50
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 1.0E-46
Sequence
Target Sequence 
>C. ELEGANS:190671_AT
gaagacaccacaacaaagctaccatgtcacaagatattatagaccgcccgagttgcttct
aggctccaaaaactatggatgcaagattgacacttggtcgtgtggatgtgtctttggtga
attgcttaaaggtggaatcttcctggcagggaaatcagccaagaatcaggcagaagttgt
atttgatatgttcggagttccaactgcagaagatgtttcatcgatgaatgtgagcaacac
gaaatacaaagaaatcattcaatcgtatgaacctgatacttcaaaaagaacagccgattt
ggcatatctctacaatcagactgcgagtttccaaagagatcgccgaagtactgtctacaa
tacgaagattgattactctgatatgaaagattccgttgagctacttcgtcaggtgcttgt
ctacaatccgagcagacgactctgtggaatagaatttctcacgaatccattcttcaccgt
gttgttcaacgagaagactgtgcgtttcaataaaaagaagatccaatgcgtgtcagctgt
cgat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAAGACACCACAACAAAGCTACCAT 165 339 552 Antisense
AAGATATTATAGACCGCCCGAGTTG 107 155 582 Antisense
CGAGTTGCTTCTAGGCTCCAAAAAC 282 249 600 Antisense
GGTCGTGTGGATGTGTCTTTGGTGA 247 503 647 Antisense
GGCATATCTCTACAATCAGACTGCG 36 537 852 Antisense
GAGATCGCCGAAGTACTGTCTACAA 340 397 887 Antisense
AAAGATTCCGTTGAGCTACTTCGTC 35 121 937 Antisense
TACTTCGTCAGGTGCTTGTCTACAA 697 643 953 Antisense
CAATCCGAGCAGACGACTCTGTGGA 223 181 975 Antisense
GAATCCATTCTTCACCGTGTTGTTC 507 327 1014 Antisense
GATCCAATGCGTGTCAGCTGTCGAT 607 415 1071 Antisense
Sequence Source Affymetrix Proprietary Database