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[190653_s_at] Serine protease inhibitor

Description ZC84.6 /REP_DB=WormBase Gene ID /WP=CE15024 /TR=O62504 /GB=CAA79570.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=Serine protease inhibitor
Cluster 6grp_total > 26      4grp_total > 42      6grp_total_sub > Cup      4grp_rule_based > L2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 128
1 2 3 4 range
A 5.9
(-3)
A 		99
(3)
A 		50.3
(-0.1)
A 		16.3
(-2.3)
A 		93
B 5.4
(-2.9)
A 		117.9
(3)
A 		51.9
(-0.5)
A 		4.3
(-3)
A 		114
C 8.8
(-3)
A 		132.7
(3)
A 		93.4
(1.1)
A 		95.4
(1.2)
A 		124
avr 6.7
(-3) 		116.5
(3) 		65.2
(0.2) 		38.7
(-1.3) 		110

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 56
1 2 3 4 5 6 range
A 9.5
(-3)
A 		28.7
(3)
A 		11.7
(-2.3)
A 		15.5
(-1.1)
A 		10.5
(-2.7)
A 		13.3
(-1.8)
A 		19
B 63.8
(3)
A 		52.4
(1.8)
A 		18.9
(-1.8)
A 		12.7
(-2.5)
A 		18
(-1.9)
A 		7.6
(-3)
A 		56
C 50.5
(3)
A 		41.8
(1.7)
A 		17
(-2.1)
A 		43.1
(1.9)
A 		11.1
(-3)
A 		48.7
(2.7)
A 		39
avr 41.3
(3) 		41
(2.9) 		15.9
(-2.4) 		23.8
(-0.7) 		13.2
(-3) 		23.2
(-0.9) 		28
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 37
1 2 3 4 range
A 2.2
(-3)
A 		21.5
(3)
A 		13.1
(0.4)
A 		2.4
(-2.9)
A 		19
B 1.7
(-2.8)
A 		29.1
(3)
A 		12
(-0.6)
A 		0.9
(-3)
A 		28
C 2.9
(-3)
A 		38.1
(3)
A 		32.6
(2.1)
A 		16.1
(-0.8)
A 		35
avr 2.3
(-3) 		29.6
(3) 		19.2
(0.7) 		6.5
(-2.1) 		27

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 20
1 2 3 4 5 6 range
A 1.8
(-3)
A 		10.2
(3)
A 		2.6
(-2.4)
A 		3.9
(-1.5)
A 		3.2
(-2)
A 		3.2
(-2)
A 		8
B 22.2
(3)
A 		17.4
(1.5)
A 		4.6
(-2.5)
A 		3.4
(-2.8)
A 		7.3
(-1.6)
A 		2.9
(-3)
A 		19
C 18.7
(3)
A 		12.8
(0.7)
A 		4.3
(-2.7)
A 		8.7
(-1)
A 		3.6
(-3)
A 		16.3
(2)
A 		15
avr 14.2
(3) 		13.5
(2.6) 		3.8
(-3) 		5.3
(-2.1) 		4.7
(-2.5) 		7.5
(-0.9) 		10
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 190653_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.6923
Sequence Type Exemplar sequence
Representative Public ID ZC84.6 NCBI
Target Description ZC84.6 /REP_DB=WormBase Gene ID /WP=CE15024 /TR=O62504 /GB=CAA79570.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=Serine protease inhibitor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_066634(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_066634 NCBI Caenorhabditis elegans ZC84.6 (ZC84.6) mRNA, complete cds. 11/11 None
SNAP00000020250 ENSEMBL cdna:SNAP chromosome:CEL140:III:9193124:9199281:-1 11/11 None
GENEFINDER00000020257 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:9193124:9199412:-1 11/11 None
ZC84.6 ENSEMBL cdna:known chromosome:CEL140:III:9192888:9199179:-1 gene:ZC84.6 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:9193119-9198962(-) 100.0 100.0
Public Domain and Genome References
Gene Title Serine protease inhibitor
Ensembl ZC84.6
Entrez Gene 176299 Entrez gene
SwissProt O62504 EMBL-EBI
WormBase CE15024 Wormbase
Functional Annotations
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
4867 serine-type endopeptidase inhibitor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA79570 Hypothetical protein ZC84.6 [Caenorhabditis elegans] ref|NP_499035.1| ZC84.6 [Caenorhabditis elegans] 0.0
blast CAE62776 Hypothetical protein CBG06945 [Caenorhabditis briggsae] 0.0
blast CAE62775 Hypothetical protein CBG06944 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR006149 EMBL-EBI Nematode-specific EB region 2.7E-30
Pfam IPR006149 EMBL-EBI Nematode-specific EB region 1.2E-23
Pfam IPR006149 EMBL-EBI Nematode-specific EB region 3.2E-24
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 4.0E-12
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 2.0E-17
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 9.6E-28
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 1.6E-24
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 7.5E-29
Pfam IPR006149 EMBL-EBI Nematode-specific EB region 2.7E-30
Pfam IPR006149 EMBL-EBI Nematode-specific EB region 1.2E-23
Pfam IPR006149 EMBL-EBI Nematode-specific EB region 3.2E-24
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 4.0E-12
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 2.0E-17
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 9.6E-28
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 1.6E-24
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 7.5E-29
Pfam IPR006149 EMBL-EBI Nematode-specific EB region 2.7E-30
Pfam IPR006149 EMBL-EBI Nematode-specific EB region 1.2E-23
Pfam IPR006149 EMBL-EBI Nematode-specific EB region 3.2E-24
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 4.0E-12
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 2.0E-17
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 9.6E-28
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 1.6E-24
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 7.5E-29
Sequence
Target Sequence 
>C. ELEGANS:190653_S_AT
aaggcaatgcatcagtggacaaccatgtccagttgggtattcatgtacttggagtccaca
agcgaaaaattatttctgttgtgcagcaaacaaactagtcatgaggacctatgttctcaa
ggacgtttgtgacggtggtgaagctttgttgttcccggcaacaaaagcaccagtgatttg
tactcgatatgcaacatgccctccaggatatttctgtagaaggtcgccaaaaacaaaaca
gacacattgttgcaaaaaacgacaacctttgaatatgcagagctatattattcagataaa
agatatcacatctaaaagacctgaacctctccgaatggctcattcgatagcatcagcagc
cgttcagatggcttcacaatatatgcacccaggacgaaggcgtcaaaaaccacagccagt
tcagaaaaccaagccagtgaaaaacgtgaagccaacgaaaaccacacttccctgcccacc
aaatcaagtgcttctagagatggaagtgaatcgaaaaataatcaaacgttgtcaagccac
gtgtcctgtctcaatgcgttcggtcaacgg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAGGCAATGCATCAGTGGACAACCA 270 159 3825 Antisense
GAGGACCTATGTTCTCAAGGACGTT 531 403 3927 Antisense
GTTCCCGGCAACAAAAGCACCAGTG 90 443 3975 Antisense
GTACTCGATATGCAACATGCCCTCC 210 459 4004 Antisense
ACATGCCCTCCAGGATATTTCTGTA 439 107 4018 Antisense
TGAACCTCTCCGAATGGCTCATTCG 116 573 4146 Antisense
CATTCGATAGCATCAGCAGCCGTTC 238 215 4165 Antisense
GCAGCCGTTCAGATGGCTTCACAAT 308 315 4180 Antisense
GCTTCACAATATATGCACCCAGGAC 622 305 4195 Antisense
CTGCCCACCAAATCAAGTGCTTCTA 210 237 4296 Antisense
CTGTCTCAATGCGTTCGGTCAACGG 509 239 4370 Antisense
Sequence Source Affymetrix Proprietary Database