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[190647_at] serine/threonine kinase

Description C14A4.13 /REP_DB=WormBase Gene ID /WP=CE02142 /TR=Q17960 /GB=CAA90134.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster 6grp_high1_10_10 > 78      4grp_high_8_8 > 20      6grp_total > 69      4grp_total > 19      6grp_high1_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 150
1 2 3 4 range
A 163.9
(-0.5)
P 		181.6
(0.2)
P 		104.6
(-3)
A 		249.4
(3)
P 		145
B 187.5
(-0.4)
P 		197.3
(0.1)
A 		136.4
(-3)
P 		254.7
(3)
P 		118
C 147.6
(-1.5)
A 		196.2
(0.6)
A 		112.1
(-3)
P 		251.5
(3)
P 		139
avr 166.3
(-0.8) 		191.7
(0.3) 		117.7
(-3) 		251.9
(3) 		134

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 187
1 2 3 4 5 6 range
A 216.3
(0.4)
P 		121.5
(-3)
A 		136.4
(-2.5)
P 		133.3
(-2.6)
A 		191.5
(-0.5)
P 		288.6
(3)
P 		167
B 151.2
(0.3)
P 		141.7
(-0.4)
P 		101.2
(-3)
A 		155.7
(0.6)
P 		192.9
(3)
P 		182.2
(2.3)
P 		92
C 123.3
(-3)
P 		155.4
(-0.6)
P 		145.8
(-1.3)
A 		135.9
(-2.1)
M 		175
(0.9)
P 		203.4
(3)
P 		80
avr 163.6
(-0.8) 		139.5
(-2.3) 		127.8
(-3) 		141.6
(-2.1) 		186.5
(0.6) 		224.7
(3) 		97
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 33
1 2 3 4 range
A 59.7
(3)
P 		39.4
(-0.8)
P 		27.3
(-3)
A 		36.5
(-1.3)
P 		32
B 59.8
(3)
P 		48.7
(0.6)
A 		31.6
(-3)
P 		54.3
(1.8)
P 		28
C 48.9
(0.4)
A 		56.4
(3)
A 		39.1
(-3)
P 		42.4
(-1.9)
P 		17
avr 56.1
(3) 		48.2
(1) 		32.7
(-3) 		44.4
(-0) 		23

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 54
1 2 3 4 5 6 range
A 39.9
(-1.5)
P 		43.2
(-1)
A 		29.7
(-3)
P 		33.8
(-2.4)
A 		57.8
(1.2)
P 		70.3
(3)
P 		41
B 52.6
(0.1)
P 		47.2
(-0.5)
P 		24.6
(-3)
A 		41.2
(-1.1)
P 		78.4
(3)
P 		67.9
(1.8)
P 		54
C 45.7
(-0.3)
P 		47.4
(-0)
P 		37.1
(-1.6)
A 		27.3
(-3)
M 		56.6
(1.3)
P 		68.1
(3)
P 		41
avr 46.1
(-0.6) 		45.9
(-0.6) 		30.5
(-3) 		34.1
(-2.4) 		64.3
(2.3) 		68.8
(3) 		38
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190647_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.2953
Sequence Type Exemplar sequence
Representative Public ID C14A4.13 NCBI
Target Description C14A4.13 /REP_DB=WormBase Gene ID /WP=CE02142 /TR=Q17960 /GB=CAA90134.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_063891(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_063891 NCBI Caenorhabditis elegans C14A4.13 (C14A4.13) mRNA, complete cds. 11/11 None
SNAP00000007398 ENSEMBL cdna:SNAP chromosome:CEL140:II:10619485:10620374:1 11/11 None
GENEFINDER00000007411 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:10619485:10620374:1 11/11 None
C14A4.13 ENSEMBL cdna:known chromosome:CEL140:II:10618382:10620374:1 gene:C14A4.13 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:10618378-10620371(+) 100.0 100.0
Public Domain and Genome References
Gene Title serine/threonine kinase
Ensembl C14A4.13
Entrez Gene 182582 Entrez gene
SwissProt Q17960 EMBL-EBI
WormBase CE02142 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA90134 Hypothetical protein C14A4.13 [Caenorhabditis elegans] emb|CAA90117.1| Hypothetical protein C14A4.13 [Caenorhabditis elegans] ref|NP_496292.1| C14A4.13 [Caenorhabditis elegans] 0.0
blast CAE59641 Hypothetical protein CBG03054 [Caenorhabditis briggsae] 0.0
blast CAA90134 Hypothetical protein C14A4.13 [Caenorhabditis elegans] emb|CAA90117.1| Hypothetical protein C14A4.13 [Caenorhabditis elegans] ref|NP_496292.1| C14A4.13 [Caenorhabditis elegans] 1.0E-140
blast CAE59641 Hypothetical protein CBG03054 [Caenorhabditis briggsae] 2.0E-78
blast CAE65704 Hypothetical protein CBG10779 [Caenorhabditis briggsae] 5.0E-69
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 0.0018
Pfam IPR000719 EMBL-EBI Protein kinase 4.0E-5
Sequence
Target Sequence 
>C. ELEGANS:190647_AT
atgattcgatgctacttgctcactcttacttattcaaaagaaccggattacgtgaagctt
cgggaggttttatgtcaaataatgacatctaagaagttcacaccggatatgcctctcgat
tggcaaaaaggtggaccttgtgaggcaatctttaagcctcaggccgcagttgtcaaacac
aaagggaccaagaaaaaagtcagcctcgcagagcttcttgatctaccaaaacctggtggc
aaagtttacacagagcgagatttcccacagccaggagaacaagagccaatgagagatgaa
tcagtatcaaagagtgatgacacgattattgagaaggaaggtccaccacctgcaccgaag
cctgtttcaaaaccagttccaccaaaaccaggagttacgatgagcttgaaaccacaactg
gctcaacaacggtgttccgcagagcacaaagatcttagcacacctcctgctattgctcgt
tcaccgattggacaaaacacgactatgaaaccgcccgtgactgcaattccacgtcctccg
attgagaagcacagtgtgagaaaagcagcaccagtagcacattctccacggaaatcga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATGATTCGATGCTACTTGCTCACTC 581 45 799 Antisense
ACACCGGATATGCCTCTCGATTGGC 520 109 898 Antisense
TTAAGCCTCAGGCCGCAGTTGTCAA 322 685 950 Antisense
AAAAGTCAGCCTCGCAGAGCTTCTT 5 133 993 Antisense
AGAGCTTCTTGATCTACCAAAACCT 312 69 1008 Antisense
TACACAGAGCGAGATTTCCCACAGC 701 639 1045 Antisense
GCCTGTTTCAAAACCAGTTCCACCA 439 279 1158 Antisense
ACAAAGATCTTAGCACACCTCCTGC 371 111 1244 Antisense
TGCTATTGCTCGTTCACCGATTGGA 397 579 1266 Antisense
ATTCCACGTCCTCCGATTGAGAAGC 662 7 1324 Antisense
GTAGCACATTCTCCACGGAAATCGA 454 455 1372 Antisense
Sequence Source Affymetrix Proprietary Database