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[190645_s_at] cyclophilin

Description Y87G2A.6 /REP_DB=WormBase Gene ID /WP=CE24686 /GEN=cyp-15 /TR=Q9U1Q3 /GB=CAB60429.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=cyclophilin
Cluster 6grp_highest_10_10 > 95      6grp_high1_10_10 > 69      4grp_highest_8_8 > 26      4grp_high_8_8 > 59      6grp_highest_nonorm > 83      6grp_total > 89      4grp_total > 60      6grp_highest_sub > Cu      6grp_cgc > 29      6grp_high1_sub > Cu      6grp_cgc_sub > Cu      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 406
1 2 3 4 range
A 537.4
(1.2)
P 		487.5
(0.4)
P 		661.8
(3)
P 		256.2
(-3)
P 		406
B 596.1
(3)
P 		456.2
(-0.5)
P 		577.9
(2.5)
P 		359.3
(-3)
P 		237
C 493.3
(0.1)
P 		444.8
(-1.2)
P 		593.6
(3)
P 		383.5
(-3)
P 		210
avr 542.3
(1.5) 		462.8
(-0.2) 		611.1
(3) 		333
(-3) 		278

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 461
1 2 3 4 5 6 range
A 353.7
(-3)
P 		488.9
(-1)
P 		465.1
(-1.3)
P 		362.6
(-2.9)
P 		758.6
(3)
P 		526.3
(-0.4)
P 		405
B 427.9
(0.3)
P 		445
(1.1)
P 		392.6
(-1.2)
P 		350.4
(-3)
P 		433.1
(0.6)
P 		489.6
(3)
P 		139
C 599.7
(2.7)
P 		525
(1.3)
P 		415.8
(-0.8)
P 		297.2
(-3)
P 		422.2
(-0.6)
P 		613.9
(3)
P 		317
avr 460.4
(0.6) 		486.3
(1.3) 		424.5
(-0.5) 		336.7
(-3) 		538
(2.8) 		543.3
(3) 		207
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 169
1 2 3 4 range
A 195.7
(3)
P 		105.8
(-0.4)
P 		173
(2.1)
P 		37.5
(-3)
P 		158
B 190.1
(3)
P 		112.7
(-1.1)
P 		133.9
(0)
P 		76.6
(-3)
P 		114
C 163.3
(1.2)
P 		127.9
(-0.3)
P 		206.9
(3)
P 		64.7
(-3)
P 		142
avr 183
(3) 		115.5
(-0.3) 		171.3
(2.4) 		59.6
(-3) 		123

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 169
1 2 3 4 5 6 range
A 65.2
(-3)
P 		173.9
(1)
P 		101.3
(-1.7)
P 		92
(-2)
P 		228.9
(3)
P 		128.1
(-0.7)
P 		164
B 148.9
(0.7)
P 		148.1
(0.7)
P 		95.3
(-2.8)
P 		92.8
(-3)
P 		176
(2.6)
P 		182.6
(3)
P 		90
C 222.3
(3)
P 		160.2
(0.7)
P 		105.8
(-1.3)
P 		59.8
(-3)
P 		136.6
(-0.2)
P 		205.5
(2.4)
P 		163
avr 145.5
(0.9) 		160.7
(1.8) 		100.8
(-1.8) 		81.5
(-3) 		180.5
(3) 		172.1
(2.5) 		99
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 190645_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.2523
Sequence Type Exemplar sequence
Representative Public ID Y87G2A.6 NCBI
Target Description Y87G2A.6 /REP_DB=WormBase Gene ID /WP=CE24686 /GEN=cyp-15 /TR=Q9U1Q3 /GB=CAB60429.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=cyclophilin
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_060977(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_060977 NCBI Caenorhabditis elegans Y87G2A.6 (cyclophilin) mRNA, complete cds. 11/11 None
SNAP00000019590 ENSEMBL cdna:SNAP chromosome:CEL140:I:13573201:13580155:-1 11/11 None
GENEFINDER00000019614 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:13574575:13580155:-1 11/11 None
Y87G2A.6.2 ENSEMBL cdna:known chromosome:CEL140:I:13574338:13580164:-1 gene:Y87G2A.6 11/11 None
Y87G2A.6.1 ENSEMBL cdna:known chromosome:CEL140:I:13574338:13580182:-1 gene:Y87G2A.6 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:13574495-13580086(-) 100.0 100.0
Public Domain and Genome References
Gene Title cyclophilin
Gene Symbol cyn-15
Ensembl Y87G2A.6
Entrez Gene 173225 Entrez gene
SwissProt Q9U1Q3 EMBL-EBI
WormBase CE24686 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:252644_AT peptidyl-prolyl cis-trans isomerase cyclophilin-type family protein at
CANINE:1587598_AT similar to peptidylprolyl isomerase domain and WD repeat containing 1 cfa
CANINE_2:CFA.10581.1.S1_S_AT similar to peptidylprolyl isomerase domain and WD repeat containing 1 cfa
DROSOPHILA_2:1638897_AT dm
DROSGENOME1:154878_AT dm
CHICKEN:GGAAFFX.9370.1.S1_AT similar to KIAA0073 protein gga
HG-U133A:213483_AT peptidylprolyl isomerase domain and WD repeat containing 1 hs
HG-U133A_2:213483_AT peptidylprolyl isomerase domain and WD repeat containing 1 hs
HG-U133_PLUS_2:213483_AT peptidylprolyl isomerase domain and WD repeat containing 1 hs
HU35KSUBA:RC_AA432386_S_AT peptidylprolyl isomerase domain and WD repeat containing 1 hs
HU35KSUBB:RC_AA029328_S_AT peptidylprolyl isomerase domain and WD repeat containing 1 hs
HUGENEFL:D38552_AT peptidylprolyl isomerase domain and WD repeat containing 1 hs
U133_X3P:HS.1191.0.S1_3P_AT peptidylprolyl isomerase domain and WD repeat containing 1 hs
HG-U95AV2:41638_AT peptidylprolyl isomerase domain and WD repeat containing 1 hs
HG-U133_PLUS_2:236999_AT Peptidylprolyl isomerase domain and WD repeat containing 1 hs
HG-U133B:236999_AT Peptidylprolyl isomerase domain and WD repeat containing 1 hs
HU35KSUBB:RC_H90887_AT Peptidylprolyl isomerase domain and WD repeat containing 1 hs
U133_X3P:HS.18357.0.A1_3P_AT Peptidylprolyl isomerase domain and WD repeat containing 1 hs
HG-U95C:62686_AT Peptidylprolyl isomerase domain and WD repeat containing 1 hs
MOE430B:1456359_AT peptidylprolyl isomerase domain and WD repeat containing 1 mm
MOUSE430_2:1456359_AT peptidylprolyl isomerase domain and WD repeat containing 1 mm
RG-U34C:RC_AI178917_AT similar to RIKEN cDNA 4632422M10 (predicted) rn
RAE230B:1379665_AT similar to RIKEN cDNA 4632422M10 (predicted) rn
RAT230_2:1379665_AT similar to RIKEN cDNA 4632422M10 (predicted) rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6457 protein folding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB60429 Hypothetical protein Y87G2A.6 [Caenorhabditis elegans] ref|NP_493378.1| Y87G2A.6 [Caenorhabditis elegans] 0.0
blast CAE63553 Hypothetical protein CBG08039 [Caenorhabditis briggsae] 0.0
blast T27467 hypothetical protein Y87G2A.o - Caenorhabditis elegans 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR002130 EMBL-EBI Peptidyl-prolyl cis-trans isomerase, cyclophilin type 5.6E-58
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 0.11
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 0.026
Pfam IPR002130 EMBL-EBI Peptidyl-prolyl cis-trans isomerase, cyclophilin type 1.1E-48
Pfam IPR002130 EMBL-EBI Peptidyl-prolyl cis-trans isomerase, cyclophilin type 1.7E-57
Trans Membrane
ID Number Of Domains Domain Boundaries
GENEFINDER00000019614 1 661-683
Sequence
Target Sequence 
>C. ELEGANS:190645_S_AT
atcgattctacctattcacgaacactgagccgtataacgttgaagacgatgaaggaaatc
cgtcagtttccggaagagatgtgtttaatgagaggccaaagaaggaggatctactgacag
cgttggatacggaaggaggtgagaaagtactgaataaagaagcaataatccatacatcat
tcggtgatatcacaattcgtcttttcggtgatgaatgtccaaaaaccgttgaaaacttct
gtacccactcacgtcgtggatattataatgggctaacattccatcgagtcatcaaatcat
ttatgattcaaactggtgatccatctggaaaaggaactggtggagaatcaatttggggtg
aagattttgaagatgaatttcatcccagacttcgacacgataaacctttcaaagtttcaa
tggcaaatgctggtggtggaaatacgaatggatcacagttttttattactgtatgcccgg
ctgattggttggatg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATCGATTCTACCTATTCACGAACAC 303 31 1277 Antisense
CACGAACACTGAGCCGTATAACGTT 429 181 1293 Antisense
GAAGGAGGATCTACTGACAGCGTTG 52 335 1377 Antisense
GCAATAATCCATACATCATTCGGTG 340 321 1438 Antisense
GTGATATCACAATTCGTCTTTTCGG 349 485 1460 Antisense
CGTTGAAAACTTCTGTACCCACTCA 60 223 1503 Antisense
GTACCCACTCACGTCGTGGATATTA 329 459 1517 Antisense
GGCTAACATTCCATCGAGTCATCAA 282 539 1547 Antisense
TGAATTTCATCCCAGACTTCGACAC 165 577 1650 Antisense
GTTTTTTATTACTGTATGCCCGGCT 246 447 1734 Antisense
GTATGCCCGGCTGATTGGTTGGATG 440 455 1747 Antisense
Sequence Source Affymetrix Proprietary Database