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[190643_at] tyrosine-protein kinase

Description H37N21.1 /REP_DB=WormBase Gene ID /WP=CE16187 /TR=O45668 /GB=CAA99888.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=tyrosine-protein kinase
Cluster 6grp_total > 55      4grp_total > 12      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 257
1 2 3 4 range
A 100
(-1)
P
39.6
(-2.5)
A
21.4
(-3)
A
261.7
(3)
P
240
B 101.3
(0.2)
P
72.3
(-1.3)
A
40.2
(-3)
A
155.6
(3)
P
115
C 102.2
(-0.4)
P
74
(-1.2)
A
5.1
(-3)
A
232.2
(3)
P
227
avr 101.2
(-0.6)
62
(-1.8)
22.2
(-3)
216.5
(3)
194

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 97
1 2 3 4 5 6 range
A 38
(-2.8)
A
42.8
(-2)
A
74
(3)
A
55.4
(0)
A
36.7
(-3)
A
66.6
(1.8)
A
37
B 58
(2)
A
51.8
(1.3)
A
66.2
(3)
A
16.3
(-3)
A
34.5
(-0.8)
A
54.4
(1.6)
P
50
C 16.2
(-2.6)
A
60.7
(0.1)
P
55.7
(-0.2)
A
63.2
(0.3)
A
10.1
(-3)
A
107.1
(3)
P
97
avr 37.4
(-1.7)
51.8
(0)
65.3
(1.7)
45
(-0.8)
27.1
(-3)
76
(3)
49
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 37
1 2 3 4 range
A 36.4
(2.7)
P
8.6
(-2.4)
A
5.6
(-3)
A
38.3
(3)
P
33
B 32.3
(2.8)
P
17.9
(-0.8)
A
9.3
(-3)
A
33.2
(3)
P
24
C 33.8
(2.1)
P
21.3
(0.1)
A
1.8
(-3)
A
39.2
(3)
P
37
avr 34.2
(2.5)
15.9
(-1)
5.6
(-3)
36.9
(3)
31

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 33
1 2 3 4 5 6 range
A 7
(-3)
A
15.2
(2.3)
A
16.1
(2.9)
A
14.1
(1.6)
A
11.1
(-0.3)
A
16.2
(3)
A
9
B 20.2
(3)
A
17.2
(1.8)
A
16.1
(1.4)
A
4.3
(-3)
A
14
(0.6)
A
20.3
(3)
P
16
C 6
(-2.5)
A
18.5
(-0.2)
P
14.2
(-1)
A
12.7
(-1.3)
A
3.3
(-3)
A
35.9
(3)
P
33
avr 11.1
(-2.3)
17
(0.1)
15.5
(-0.5)
10.4
(-2.6)
9.5
(-3)
24.1
(3)
15
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190643_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.1230
Sequence Type Exemplar sequence
Representative Public ID H37N21.1 NCBI
Target Description H37N21.1 /REP_DB=WormBase Gene ID /WP=CE16187 /TR=O45668 /GB=CAA99888.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=tyrosine-protein kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059621(10)
Transcript Assignments
Representative
Transcript
Description Matching Probes Related Probesets by Grade
NM_059621 NCBI Caenorhabditis elegans H37N21.1 (H37N21.1) mRNA, complete cds. 10/11 None
SNAP00000020205 ENSEMBL cdna:SNAP chromosome:CEL140:I:7153584:7155362:-1 10/11 None
H37N21.1 ENSEMBL cdna:known chromosome:CEL140:I:7148410:7155362:-1 gene:H37N21.1 10/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:7153410-7155293(-) 100.0 100.0
Public Domain and Genome References
Gene Title tyrosine-protein kinase
Ensembl H37N21.1
Entrez Gene 186807 Entrez gene
SwissProt O45668 EMBL-EBI
WormBase CE36873 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1586649_AT similar to nuclear receptor binding protein cfa
CANINE_2:CFA.8989.1.A1_AT similar to nuclear receptor binding protein cfa
CANINE_2:CFAAFFX.8356.1.S1_AT similar to nuclear receptor binding protein cfa
CANINE_2:CFAAFFX.8356.1.S1_S_AT similar to nuclear receptor binding protein cfa
DROSOPHILA_2:1639453_AT MLF1-adaptor molecule dm
DROSGENOME1:144182_AT MLF1-adaptor molecule dm
CHICKEN:GGA.7224.2.S1_AT nuclear receptor binding protein gga
CHICKEN:GGA.7224.2.S1_S_AT nuclear receptor binding protein gga
CHICKEN:GGAAFFX.10561.1.S1_AT nuclear receptor binding protein gga
CHICKEN:GGAAFFX.10561.2.S1_S_AT nuclear receptor binding protein gga
HG-U133_PLUS_2:217765_AT nuclear receptor binding protein hs
HG-U133A:217765_AT nuclear receptor binding protein hs
HG-FOCUS:217765_AT nuclear receptor binding protein hs
HG-U133A_2:217765_AT nuclear receptor binding protein hs
HU35KSUBC:RC_AA610087_F_AT nuclear receptor binding protein hs
HU35KSUBD:RC_W59987_AT nuclear receptor binding protein hs
HU35KSUBD:RC_W45701_F_AT nuclear receptor binding protein hs
HU35KSUBD:RC_R45977_F_AT nuclear receptor binding protein hs
U133_X3P:G7019332_3P_X_AT nuclear receptor binding protein hs
U133_X3P:G7019332_3P_AT nuclear receptor binding protein hs
HG-U95B:56439_AT nuclear receptor binding protein hs
HU35KSUBD:RC_C21229_AT Nuclear receptor binding protein hs
MG-U74AV2:94059_AT nuclear receptor binding protein mm
MOE430A:1423864_AT nuclear receptor binding protein mm
MOUSE430A_2:1423864_AT nuclear receptor binding protein mm
MOUSE430_2:1423864_AT nuclear receptor binding protein mm
MOUSE430_2:1444600_AT Nuclear receptor binding protein (Nrbp), mRNA mm
MOE430B:1444600_AT Nuclear receptor binding protein (Nrbp), mRNA mm
MU19KSUBB:TC31595_AT Nuclear receptor binding protein (Nrbp), mRNA mm
MU19KSUBB:TC31595_G_AT Nuclear receptor binding protein (Nrbp), mRNA mm
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA99888 Hypothetical protein H37N21.1 [Caenorhabditis elegans] emb|CAA15621.2| Hypothetical protein H37N21.1 [Caenorhabditis elegans] ref|NP_492022.2| H37N21.1 [Caenorhabditis elegans] 0.0
blast T23574 hypothetical protein K10D3.5 - Caenorhabditis elegans 0.0
blast CAE73126 Hypothetical protein CBG20509 [Caenorhabditis briggsae] 1.0E-120
blast CAA99888 Hypothetical protein H37N21.1 [Caenorhabditis elegans] emb|CAA15621.2| Hypothetical protein H37N21.1 [Caenorhabditis elegans] ref|NP_492022.2| H37N21.1 [Caenorhabditis elegans] 1.0E-102
blast CAE73125 Hypothetical protein CBG20508 [Caenorhabditis briggsae] 1.0E-97
blast XP_623819 PREDICTED: similar to ENSANGP00000011826 [Apis mellifera] 5.0E-69
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 7.3E-13
Pfam IPR000719 EMBL-EBI Protein kinase 0.068
Pfam IPR000719 EMBL-EBI Protein kinase 1.5E-7
Sequence
Target Sequence
>C. ELEGANS:190643_AT
gagtcaccggacaaacgatggtcaaaacgaagagaacaagtgaaacagagagatgtaccc
ggtatagacgtcgcctatcttgcaatggataacgaaactggtaacgaagttgtctggaat
gaagttcaattttcggaaaggaaaaactttcgagcacaagaggaaaaaatcaacgctgta
ttcgataatctgactcaattagttcatacaaatctagtaaagtttcataaatattggaca
gattcaaagtcggaaaaaccaaggataatattcatcacagaatatatgtcatccggttca
atgtcagcatttcttcaaagaacacgaaaagccggctcatcacttagcattaaggcttgg
aaaaagtggacgacgcaaattttgtcagcattaaactaccttcattcatcggatccacct
ataattcatggaaatctgacgtgtaatacggtgtttattcagcaaaatggtctcataaaa
attggatgtggtgagttccagttttttgctgtaa


BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position
Strandedness
GAGTCACCGGACAAACGATGGTCAA 536 399 115 Antisense
AGATGTACCCGGTATAGACGTCGCC 360 63 165 Antisense
TATAGACGTCGCCTATCTTGCAATG 2 657 177 Antisense
AACGCTGTATTCGATAATCTGACTC 48 147 286 Antisense
ATGTCATCCGGTTCAATGTCAGCAT 553 47 400 Antisense
AAAGAACACGAAAAGCCGGCTCATC 604 123 431 Antisense
AAGCCGGCTCATCACTTAGCATTAA 27 149 443 Antisense
GGACGACGCAAATTTTGTCAGCATT 539 523 482 Antisense
GTCAGCATTAAACTACCTTCATTCA 423 465 498 Antisense
CATTCATCGGATCCACCTATAATTC 575 215 517 Antisense
GGTGAGTTCCAGTTTTTTGCTGTAA 193 501 604 Antisense
Sequence Source Affymetrix Proprietary Database