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[190639_s_at] Apoptosis protein RP-8

Description R07E5.10 /REP_DB=WormBase Gene ID /WP=CE18125 /TR=Q21826 /GB=CAA83630.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=Apoptosis protein RP-8
Cluster 6grp_highest_10_10 > 63      6grp_high1_10_10 > 35      4grp_highest_8_8 > 30      4grp_high_8_8 > 05      6grp_highest_nonorm > 75      6grp_total > 36      4grp_total > 04      6grp_highest_sub > Cu      6grp_high1_sub > 02      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2403
1 2 3 4 range
A 1009.1
(-1.6)
P 		572.2
(-3)
P 		579.6
(-3)
P 		2465.4
(3)
P 		1893
B 908.9
(-1.6)
P 		345.4
(-3)
P 		604.8
(-2.4)
P 		2748.3
(3)
P 		2403
C 987.2
(-1.3)
P 		385.5
(-3)
P 		645.4
(-2.3)
P 		2473.5
(3)
P 		2088
avr 968.4
(-1.5) 		434.4
(-3) 		609.9
(-2.5) 		2562.4
(3) 		2128

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 552
1 2 3 4 5 6 range
A 1016.2
(3)
P 		739.6
(-1.6)
P 		824.6
(-0.2)
P 		651.8
(-3)
P 		699.2
(-2.2)
P 		919
(1.4)
P 		364
B 990.3
(1.7)
P 		1078.9
(3)
P 		929.7
(0.7)
P 		712.7
(-2.6)
P 		685
(-3)
P 		884.8
(0)
P 		394
C 789.8
(-1.3)
P 		1183.8
(3)
P 		678.8
(-2.5)
P 		963.9
(0.6)
P 		632.3
(-3)
P 		950.7
(0.5)
P 		552
avr 932.1
(1.7) 		1000.8
(3) 		811
(-0.5) 		776.1
(-1.1) 		672.2
(-3) 		918.2
(1.5) 		329
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 500
1 2 3 4 range
A 367.4
(3)
P 		124.2
(-3)
P 		151.5
(-2.3)
P 		360.9
(2.8)
P 		243
B 289.8
(-0.5)
P 		85.3
(-3)
P 		140.1
(-2.3)
P 		585.7
(3)
P 		500
C 326.8
(1.2)
P 		110.8
(-3)
P 		224.9
(-0.8)
P 		417.1
(3)
P 		306
avr 328
(0.8) 		106.8
(-3) 		172.2
(-1.9) 		454.6
(3) 		348

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 196
1 2 3 4 5 6 range
A 187.3
(-1.6)
P 		263
(3)
P 		179.6
(-2.1)
P 		165.3
(-3)
P 		211
(-0.2)
P 		223.7
(0.6)
P 		98
B 344.6
(2.5)
P 		359.1
(3)
P 		225.8
(-1.7)
P 		188.8
(-3)
P 		278.3
(0.2)
P 		329.9
(2)
P 		170
C 292.8
(0.8)
P 		361.2
(3)
P 		172.8
(-3)
P 		193.8
(-2.3)
P 		204.6
(-2)
P 		318.3
(1.6)
P 		188
avr 274.9
(0.8) 		327.8
(3) 		192.7
(-2.6) 		182.6
(-3) 		231.3
(-1) 		290.6
(1.5) 		145
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 190639_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.7602
Sequence Type Exemplar sequence
Representative Public ID R07E5.10 NCBI
Target Description R07E5.10 /REP_DB=WormBase Gene ID /WP=CE18125 /TR=Q21826 /GB=CAA83630.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=Apoptosis protein RP-8
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_065495(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_065495 NCBI Caenorhabditis elegans R07E5.10 (R07E5.10) mRNA, complete cds. 11/11 None
SNAP00000012853 ENSEMBL cdna:SNAP chromosome:CEL140:III:4414809:4418021:-1 11/11 None
GENEFINDER00000012869 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:4415567:4418021:-1 11/11 None
R07E5.10 ENSEMBL cdna:known chromosome:CEL140:III:4415507:4417783:-1 gene:R07E5.10 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:4415566-4417630(-) 100.0 100.0
Public Domain and Genome References
Gene Title Apoptosis protein RP-8
Ensembl R07E5.10
Entrez Gene 259501 Entrez gene
SwissProt Q21826 EMBL-EBI
WormBase CE18125 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:13386_AT zinc finger (MYND type) family protein / programmed cell death 2 C-terminal domain-containing protein at
ATH1-121501:255508_AT zinc finger (MYND type) family protein / programmed cell death 2 C-terminal domain-containing protein at
CANINE:1602873_AT similar to programmed cell death 2 isoform 1 cfa
CANINE:1598981_X_AT similar to programmed cell death 2 isoform 1 cfa
CANINE:1597154_AT similar to programmed cell death 2 isoform 1 cfa
CANINE:1593933_AT similar to programmed cell death 2 isoform 1 cfa
CANINE_2:CFA.4486.5.A1_AT similar to programmed cell death 2 isoform 1 cfa
CANINE_2:CFAAFFX.7087.1.S1_S_AT similar to programmed cell death 2 isoform 1 cfa
DROSOPHILA_2:1639659_AT Zinc finger protein RP-8 dm
DROSGENOME1:147841_AT Zinc finger protein RP-8 dm
CHICKEN:GGAAFFX.7095.1.S1_AT programmed cell death 2 gga
CHICKEN:GGAAFFX.7095.1.S1_S_AT programmed cell death 2 gga
CHICKEN:GGAAFFX.7095.2.S1_AT programmed cell death 2 gga
HG-U95AV2:855_AT programmed cell death 2 hs
HC-G110:855_AT programmed cell death 2 hs
HG-U133A_2:204025_S_AT programmed cell death 2 hs
HG-U133A:204025_S_AT programmed cell death 2 hs
HG-U133_PLUS_2:204025_S_AT programmed cell death 2 hs
HU35KSUBA:RC_AA215409_AT programmed cell death 2 hs
HU35KSUBD:RC_N93618_AT programmed cell death 2 hs
HUGENEFL:S78085_AT programmed cell death 2 hs
U133_X3P:G4505654_3P_AT programmed cell death 2 hs
U133_X3P:HS.41639.2.S1_3P_AT programmed cell death 2 hs
U133_X3P:HS.293297.0.A1_3P_AT programmed cell death 2 hs
HG-U133A_2:213581_AT programmed cell death 2 hs
HG-FOCUS:213581_AT programmed cell death 2 hs
HG-U133_PLUS_2:213581_AT programmed cell death 2 hs
HG-U133A:213581_AT programmed cell death 2 hs
HG-U133_PLUS_2:228420_AT programmed cell death 2 hs
HG-U133B:228420_AT programmed cell death 2 hs
HG-U95B:57526_AT programmed cell death 2 hs
HG-U95C:61637_AT programmed cell death 2 hs
HG-U95D:72254_AT programmed cell death 2 hs
HU35KSUBA:RC_D20426_AT Programmed cell death 2 hs
U133_X3P:HS.41639.1.A1_3P_A_AT Programmed cell death 2 hs
HG-U133A_2:213585_S_AT Programmed cell death 2 hs
HG-U133_PLUS_2:213585_S_AT Programmed cell death 2 hs
HG-U133A:213585_S_AT Programmed cell death 2 hs
HG-U95AV2:41560_AT Programmed cell death 2 hs
HG-U133_PLUS_2:243773_AT Programmed cell death 2 hs
HG-U133B:243773_AT Programmed cell death 2 hs
HG-U95D:92065_AT Programmed cell death 2 hs
HU35KSUBA:AA427379_AT Programmed cell death 2 hs
HU35KSUBC:RC_D12280_S_AT Programmed cell death 2 hs
U133_X3P:HS.171858.0.A1_3P_AT Programmed cell death 2 hs
MU11KSUBA:U10903_S_AT programmed cell death 2 mm
MG-U74AV2:160412_AT programmed cell death 2 mm
MOE430A:1423534_AT programmed cell death 2 mm
MOUSE430A_2:1423534_AT programmed cell death 2 mm
MOUSE430_2:1423534_AT programmed cell death 2 mm
MU19KSUBA:TC23114_AT Programmed cell death 2 (Pdcd2), mRNA mm
MU19KSUBA:TC23114_G_AT Programmed cell death 2 (Pdcd2), mRNA mm
RG-U34A:M80601_AT programmed cell death 2 rn
RAE230A:1371002_AT programmed cell death 2 rn
RAT230_2:1371002_AT programmed cell death 2 rn
RG-U34A:RC_AI176462_AT Programmed cell death 2 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6915 apoptosis inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5737 cytoplasm inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA83630 Hypothetical protein R07E5.10 [Caenorhabditis elegans] ref|NP_497896.1| R07E5.10 [Caenorhabditis elegans] 0.0
blast S43603 RNA binding protein homolog R07E5.12 - Caenorhabditis elegans 2.0E-65
blast S43603 RNA binding protein homolog R07E5.12 - Caenorhabditis elegans 3.0E-52
blast EAA11866 ENSANGP00000007243 [Anopheles gambiae str. PEST] ref|XP_315591.2| ENSANGP00000007243 [Anopheles gambiae str. PEST] 2.0E-51
blast EAA11866 ENSANGP00000007243 [Anopheles gambiae str. PEST] ref|XP_315591.2| ENSANGP00000007243 [Anopheles gambiae str. PEST] 3.0E-51
blast XP_854542 PREDICTED: similar to programmed cell death 2 isoform 1 isoform 2 [Canis familiaris] 5.0E-50
Protein Domains
Database ID Description E-Value
Pfam IPR002893 EMBL-EBI Zn-finger, MYND type 1.7E-20
Pfam IPR007320 EMBL-EBI Programmed cell death protein 2, C-terminal 4.6E-29
Pfam IPR002893 EMBL-EBI Zn-finger, MYND type 1.7E-20
Pfam IPR007320 EMBL-EBI Programmed cell death protein 2, C-terminal 1.5E-26
Pfam IPR002893 EMBL-EBI Zn-finger, MYND type 1.7E-20
Pfam IPR007320 EMBL-EBI Programmed cell death protein 2, C-terminal 4.6E-29
Trans Membrane
ID Number Of Domains Domain Boundaries
SNAP00000012853 2 31-53,66-88
GENEFINDER00000012869 1 30-49
Sequence
Target Sequence 
>C. ELEGANS:190639_S_AT
aagcggcaacagatggctccataacggatgaaccgaaaaatccaagaaatgcgttttgtt
tcaaagaattcggtgtagaaattgatcaggaatatatgccagcaaatctgtttgacggac
ttagtgatgatgaaggcgatgaggaagaggaagaaggaaatgatgaggatgagactgaag
aggagaagaaagcaagaatcagagaatttgagaaatttgtcaaggagaacaaagggaaaa
acgctgacatgacaaaggaagatttggatgaagccaccgccgagcaaccaaaagatatcg
attttgataaattcaaccgtcttgtcaatttgcaacccgatcagattattagatacaaga
gatacggacagccactccgtgcaactggcctttctgaattgccagaagttgtggaaccat
gtgaactttgtggagctcctcgtcgtttcgaaatgcagcttatgccacatctcttgtcgc
tcatcgatgtagatgctattggtcaatctatcgactgggcttccgtgtacgtgtacactt
gctccgcgagttgccagatcgctgat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAGCGGCAACAGATGGCTCCATAAC 617 147 563 Antisense
AACCGTCTTGTCAATTTGCAACCCG 493 145 877 Antisense
AGAGATACGGACAGCCACTCCGTGC 485 69 920 Antisense
GTGCAACTGGCCTTTCTGAATTGCC 557 479 941 Antisense
TGTGAACTTTGTGGAGCTCCTCGTC 246 557 982 Antisense
GCTCCTCGTCGTTTCGAAATGCAGC 352 297 997 Antisense
AATGCAGCTTATGCCACATCTCTTG 47 167 1014 Antisense
ATCTCTTGTCGCTCATCGATGTAGA 335 33 1031 Antisense
TGGTCAATCTATCGACTGGGCTTCC 281 551 1062 Antisense
CCGTGTACGTGTACACTTGCTCCGC 640 263 1085 Antisense
CTCCGCGAGTTGCCAGATCGCTGAT 453 233 1104 Antisense
Sequence Source Affymetrix Proprietary Database