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[190631_at] ser/thr-protein kinase

Description F21F3.2 /REP_DB=WormBase Gene ID /WP=CE09532 /TR=P91267 /GB=AAB42279.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=ser-thr-protein kinase
Cluster 6grp_total > 96      4grp_total > 07      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 92
1 2 3 4 range
A 46.5
(3)
A 		14.4
(-3)
A 		23
(-1.4)
A 		35.9
(1)
A 		32
B 29.6
(-1.5)
A 		16.6
(-3)
A 		67.4
(3)
A 		16.8
(-3)
A 		51
C 56.3
(0.1)
A 		7.8
(-3)
A 		10.7
(-2.8)
A 		100.2
(3)
A 		92
avr 44.1
(1.9) 		12.9
(-3) 		33.7
(0.3) 		51
(3) 		38

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 113
1 2 3 4 5 6 range
A 16.5
(-2.8)
A 		28.5
(-2.1)
A 		12.3
(-3)
A 		49.4
(-0.9)
A 		75.3
(0.6)
A 		118.6
(3)
A 		106
B 13
(-3)
A 		15.2
(-2.9)
A 		19.1
(-2.7)
A 		58.5
(-0.6)
A 		55.5
(-0.7)
A 		125
(3)
A 		112
C 37.3
(-1.7)
A 		23.3
(-3)
A 		54.8
(-0.1)
A 		41.9
(-1.3)
A 		88.6
(3)
A 		56.3
(0)
A 		65
avr 22.3
(-3) 		22.3
(-3) 		28.7
(-2.5) 		49.9
(-0.9) 		73.1
(0.9) 		100
(3) 		78
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 16
1 2 3 4 range
A 16.9
(3)
A 		3.1
(-3)
A 		6
(-1.7)
A 		5.3
(-2)
A 		14
B 9.4
(-0.1)
A 		4.1
(-2.8)
A 		15.6
(3)
A 		3.6
(-3)
A 		12
C 18.6
(3)
A 		2.2
(-3)
A 		3.7
(-2.5)
A 		16.9
(2.4)
A 		16
avr 15
(3) 		3.1
(-3) 		8.4
(-0.3) 		8.6
(-0.2) 		12

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 44
1 2 3 4 5 6 range
A 3
(-2.9)
A 		10.1
(-1.3)
A 		2.7
(-3)
A 		12.5
(-0.8)
A 		22.7
(1.6)
A 		28.9
(3)
A 		26
B 4.5
(-3)
A 		5.1
(-2.9)
A 		4.6
(-3)
A 		15.5
(-1.4)
A 		22.6
(-0.4)
A 		46.6
(3)
A 		42
C 13.8
(-1.1)
A 		7.1
(-3)
A 		13.9
(-1.1)
A 		8.4
(-2.6)
A 		28.7
(3)
A 		18.9
(0.3)
A 		22
avr 7.1
(-3) 		7.4
(-2.9) 		7.1
(-3) 		12.1
(-1.8) 		24.7
(1.3) 		31.5
(3) 		24
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190631_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.2306
Sequence Type Exemplar sequence
Representative Public ID F21F3.2 NCBI
Target Description F21F3.2 /REP_DB=WormBase Gene ID /WP=CE09532 /TR=P91267 /GB=AAB42279.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=ser-thr-protein kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059073(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_059073 NCBI Caenorhabditis elegans F21F3.2 (F21F3.2) mRNA, complete cds. 11/11 None
SNAP00000035674 ENSEMBL cdna:SNAP chromosome:CEL140:I:4903497:4905109:1 11/11 None
GENEFINDER00000035686 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:4903497:4906302:1 11/11 None
F21F3.2 ENSEMBL cdna:known chromosome:CEL140:I:4903497:4905139:1 gene:F21F3.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:4903496-4905109(+) 100.0 100.0
Public Domain and Genome References
Gene Title ser/thr-protein kinase
Ensembl F21F3.2
Entrez Gene 172107 Entrez gene
SwissProt P91267 EMBL-EBI
WormBase CE09532 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB42279 Hypothetical protein F21F3.2 [Caenorhabditis elegans] ref|NP_491474.1| F21F3.2 [Caenorhabditis elegans] 0.0
blast CAE64384 Hypothetical protein CBG09071 [Caenorhabditis briggsae] 0.0
blast T22168 hypothetical protein F44D12.11 - Caenorhabditis elegans 1.0E-162
Protein Families
Method ID Description E-Value
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 6.0E-25
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 7.0E-25
hanks 3.1.5 CMCG Group; CMGC I Cyclin-dependent (CDKs) and close relatives; Cdk6 4.0E-55
hanks 3.1.5 CMCG Group; CMGC I Cyclin-dependent (CDKs) and close relatives; Cdk6 5.0E-54
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 2.1E-53
Sequence
Target Sequence 
>C. ELEGANS:190631_AT
cgctgctttggtgccccaaatgagcaagacattagtgcgatgaagggagaaaaattggag
aaagagtattggaagtttacgaaaggattcggacttcaaagacttgtgaacgatatctca
cctgatcagctacagttcatcaagagaatcctggtgtatgctcccgagaaacgtcttcgt
ggcaaacaattgcttcaggacgacttcttccgtccgctcttcaaagctggagcagttcgt
cacaacggacagaagatttctgacgtcataactgctgctgattacaagcgagctgctgaa
aacgaagaatcctccgcatgccgtctcgcgcaattggtcaagacggacaacaaggatctt
gggattccgtattgtgagaagagcaactcatatgagaatgtttatgcgagaagatcaact
cttatcccgaaagagcagaagatggctcgtgacaacaagtcgaaagaggacagctctgac
gatcgacgtgttgcaccttctagtggagaggctccttcggctcctggcaagcgttccgag
tccaacaagaccgcggca

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CGCTGCTTTGGTGCCCCAAATGAGC 638 255 712 Antisense
GAACGATATCTCACCTGATCAGCTA 645 347 819 Antisense
AGAGAATCCTGGTGTATGCTCCCGA 642 67 854 Antisense
TGCTCCCGAGAAACGTCTTCGTGGC 549 567 870 Antisense
TCCGTCCGCTCTTCAAAGCTGGAGC 472 593 920 Antisense
GCTGGAGCAGTTCGTCACAACGGAC 131 295 937 Antisense
GATTTCTGACGTCATAACTGCTGCT 105 429 966 Antisense
TGAAAACGAAGAATCCTCCGCATGC 364 573 1008 Antisense
GCCGTCTCGCGCAATTGGTCAAGAC 651 283 1031 Antisense
GCACCTTCTAGTGGAGAGGCTCCTT 639 313 1204 Antisense
TTCCGAGTCCAACAAGACCGCGGCA 628 693 1245 Antisense
Sequence Source Affymetrix Proprietary Database