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[190630_at] serine/threonine kinase

Description ZK524.4 /REP_DB=WormBase Gene ID /WP=CE18454 /TR=Q22855 /GB=CAA98148.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster 6grp_highest_10_10 > 93      6grp_high1_10_10 > 48      4grp_highest_8_8 > 44      4grp_high_8_8 > 16      6grp_highest_nonorm > 73      6grp_total > 38      4grp_total > 39      6grp_highest_sub > Cu      6grp_high1_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 244
1 2 3 4 range
A 573
(3)
P 		329.5
(-3)
P 		360.2
(-2.2)
P 		525.9
(1.8)
P 		244
B 537
(3)
P 		371.9
(-2.6)
P 		359.3
(-3)
P 		408.5
(-1.3)
P 		178
C 567.9
(3)
P 		329.8
(-3)
P 		401.8
(-1.2)
P 		339.6
(-2.8)
P 		238
avr 559.3
(3) 		343.7
(-3) 		373.8
(-2.2) 		424.7
(-0.7) 		216

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 254
1 2 3 4 5 6 range
A 610.3
(3)
P 		530.6
(0.9)
P 		383.4
(-3)
P 		414.6
(-2.2)
P 		491.5
(-0.1)
P 		538.2
(1.1)
P 		227
B 534.2
(1.6)
P 		587.5
(3)
P 		362.9
(-3)
P 		533.2
(1.5)
P 		492.3
(0.5)
P 		550
(2)
P 		225
C 616.9
(3)
P 		556.8
(0.7)
P 		486.6
(-1.9)
P 		483.5
(-2.1)
P 		458.9
(-3)
P 		565.6
(1.1)
P 		158
avr 587.1
(3) 		558.3
(2) 		411
(-3) 		477.1
(-0.7) 		480.9
(-0.6) 		551.3
(1.8) 		176
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 151
1 2 3 4 range
A 208.6
(3)
P 		71.5
(-3)
P 		94.2
(-2)
P 		77
(-2.8)
P 		137
B 171.2
(3)
P 		91.8
(-2.4)
P 		83.3
(-3)
P 		87
(-2.7)
P 		88
C 188
(3)
P 		94.8
(-1.3)
P 		140.1
(0.8)
P 		57.3
(-3)
P 		131
avr 189.3
(3) 		86
(-2.4) 		105.9
(-1.3) 		73.8
(-3) 		116

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 145
1 2 3 4 5 6 range
A 112.5
(-1.3)
P 		188.7
(3)
P 		83.5
(-3)
P 		105.1
(-1.8)
P 		148.3
(0.7)
P 		131
(-0.3)
P 		105
B 185.9
(2)
P 		195.6
(2.5)
P 		88.1
(-3)
P 		141.2
(-0.3)
P 		200
(2.7)
P 		205.1
(3)
P 		117
C 228.7
(3)
P 		169.9
(0.3)
P 		123.8
(-1.8)
P 		97.2
(-3)
P 		148.5
(-0.7)
P 		189.3
(1.2)
P 		132
avr 175.7
(2.4) 		184.7
(3) 		98.5
(-3) 		114.5
(-1.9) 		165.6
(1.7) 		175.1
(2.3) 		86
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190630_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.2066
Sequence Type Exemplar sequence
Representative Public ID ZK524.4 NCBI
Target Description ZK524.4 /REP_DB=WormBase Gene ID /WP=CE18454 /TR=Q22855 /GB=CAA98148.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059696(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_059696 NCBI Caenorhabditis elegans ZK524.4 (ZK524.4) mRNA, complete cds. 11/11 None
ZK524.4 ENSEMBL cdna:known chromosome:CEL140:I:7468993:7474549:-1 gene:ZK524.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:7469423-7474480(-) 100.0 100.0
Public Domain and Genome References
Gene Title serine/threonine kinase
Ensembl ZK524.4
Entrez Gene 172500 Entrez gene
SwissProt Q22855 EMBL-EBI
WormBase CE18454 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA98148 Hypothetical protein ZK524.4 [Caenorhabditis elegans] emb|CAA96698.1| Hypothetical protein ZK524.4 [Caenorhabditis elegans] ref|NP_492097.1| ZK524.4 [Caenorhabditis elegans] 0.0
blast CAE56825 Hypothetical protein CBG24641 [Caenorhabditis briggsae] 0.0
blast EAA01241 ENSANGP00000008479 [Anopheles gambiae str. PEST] ref|XP_321330.2| ENSANGP00000008479 [Anopheles gambiae str. PEST] 1.0E-128
Protein Families
Method ID Description E-Value
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 1.0E-63
hanks 2.2.11 CaMK Group; CaMK II KIN1/SNF1/Nim1; YKL453 6.0E-77
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 8.7E-80
Sequence
Target Sequence 
>C. ELEGANS:190630_AT
gaacgacatctcttactgtaactggtaaacaatctaataatcagtctggaatagctccac
aatcaaatgagaaaagatcaacactcaatgattcggtacttccacttcgaccaattcctg
aaatgactctgcttgatcagacgcttacttcaccggattgtgcatcaattcgtgaccgaa
tcctacacacttccttaagtactcaaactatgattcgaaaatggacagaaatggattcat
ggtacggtacaccaccaagagattacgaagatcgaactcacttacacgagaagaccccat
ggcttcgatgccttcgtcgaactgcatcaagtcaagatttattaagagaaagtgacgaaa
aagccacgagtgaacatggaaatgattctggatgttctacaacagaaaaagacggagaac
atcagtgtacatctccacagtttatacaacaaaatatgtataacgattcgaaattctcat
ttctgaatactttgcccatggag

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAACGACATCTCTTACTGTAACTGG 530 347 2519 Antisense
TCAATGATTCGGTACTTCCACTTCG 617 631 2603 Antisense
TTCCACTTCGACCAATTCCTGAAAT 557 699 2618 Antisense
GACTCTGCTTGATCAGACGCTTACT 353 371 2643 Antisense
ACGCTTACTTCACCGGATTGTGCAT 44 93 2659 Antisense
ATTCGTGACCGAATCCTACACACTT 600 9 2686 Antisense
GGATTCATGGTACGGTACACCACCA 620 507 2751 Antisense
ACGAGAAGACCCCATGGCTTCGATG 426 91 2804 Antisense
TGCCTTCGTCGAACTGCATCAAGTC 581 585 2827 Antisense
AACATCAGTGTACATCTCCACAGTT 65 139 2936 Antisense
ATTTCTGAATACTTTGCCCATGGAG 186 17 2997 Antisense
Sequence Source Affymetrix Proprietary Database