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[190621_s_at] serine/threonine kinase

Description ZK596.2 /REP_DB=WormBase Gene ID /WP=CE06632 /TR=Q23546 /GB=CAA93431.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster 6grp_total > 88      4grp_total > 35      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 58
1 2 3 4 range
A 13.9
(-2.5)
A 		67.6
(3)
A 		9.5
(-3)
A 		10.8
(-2.9)
A 		58
B 13.3
(-2.4)
A 		12.8
(-2.5)
A 		9.7
(-3)
A 		48
(3)
A 		38
C 14.5
(-3)
A 		38.9
(1.8)
A 		26.5
(-0.7)
A 		45.2
(3)
A 		31
avr 13.9
(-3) 		39.8
(3) 		15.2
(-2.7) 		34.7
(1.8) 		26

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 203
1 2 3 4 5 6 range
A 66.5
(-1.2)
A 		9.6
(-2.9)
A 		28.7
(-2.4)
A 		7.9
(-3)
A 		111.7
(0.1)
A 		206.4
(3)
A 		199
B 28.2
(-2.3)
A 		3.7
(-3)
A 		24.2
(-2.4)
A 		11
(-2.8)
A 		135
(0.9)
A 		204.7
(3)
P 		201
C 37.5
(-1.9)
A 		56.2
(-1)
A 		13.4
(-3)
A 		61.2
(-0.7)
A 		88.7
(0.6)
A 		140.3
(3)
P 		127
avr 44.1
(-2.2) 		23.2
(-3) 		22.1
(-3) 		26.7
(-2.8) 		111.8
(0.3) 		183.8
(3) 		162
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 13
1 2 3 4 range
A 5.1
(-1.4)
A 		14.7
(3)
A 		2.5
(-2.6)
A 		1.6
(-3)
A 		13
B 4.2
(-1.6)
A 		3.2
(-2.3)
A 		2.3
(-3)
A 		10.2
(3)
A 		8
C 4.8
(-3)
A 		11.2
(3)
A 		9.2
(1.1)
A 		7.6
(-0.4)
A 		6
avr 4.7
(-3) 		9.7
(3) 		4.7
(-3) 		6.5
(-0.8) 		5

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 75
1 2 3 4 5 6 range
A 12.3
(-1.7)
A 		3.4
(-2.8)
A 		6.2
(-2.5)
A 		2
(-3)
A 		33.7
(0.9)
A 		50.2
(3)
A 		48
B 9.8
(-2.3)
A 		1.2
(-3)
A 		5.9
(-2.6)
A 		2.9
(-2.9)
A 		54.8
(1.3)
A 		76.3
(3)
P 		75
C 13.9
(-1.6)
A 		17.1
(-1.1)
A 		3.4
(-3)
A 		12.3
(-1.8)
A 		28.7
(0.5)
A 		47
(3)
P 		44
avr 12
(-2.2) 		7.2
(-2.8) 		5.2
(-3) 		5.7
(-2.9) 		39.1
(0.9) 		57.8
(3) 		53
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 190621_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.9132
Sequence Type Exemplar sequence
Representative Public ID ZK596.2 NCBI
Target Description ZK596.2 /REP_DB=WormBase Gene ID /WP=CE06632 /TR=Q23546 /GB=CAA93431.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069627(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069627 NCBI Caenorhabditis elegans ZK596.2 (ZK596.2) mRNA, complete cds. 11/11 None
SNAP00000015318 ENSEMBL cdna:SNAP chromosome:CEL140:IV:10908122:10909209:-1 11/11 None
GENEFINDER00000015319 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:10908122:10909209:-1 11/11 None
ZK596.2 ENSEMBL cdna:known chromosome:CEL140:IV:10908122:10909241:-1 gene:ZK596.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:10908127-10909215(-) 100.0 100.0
Public Domain and Genome References
Gene Title serine/threonine kinase
Ensembl ZK596.2
Entrez Gene 177983 Entrez gene
SwissProt Q23546 EMBL-EBI
WormBase CE06632 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA93431 Hypothetical protein ZK596.2 [Caenorhabditis elegans] ref|NP_502028.1| ZK596.2 [Caenorhabditis elegans] 1.0E-177
blast CAE66831 Hypothetical protein CBG12201 [Caenorhabditis briggsae] 1.0E-167
blast CAA97422 Hypothetical protein C08F8.6 [Caenorhabditis elegans] ref|NP_502093.1| C08F8.6 [Caenorhabditis elegans] 1.0E-101
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 4.4E-19
Sequence
Target Sequence 
>C. ELEGANS:190621_S_AT
tctccgcaaaactgctccattcaacaaattctcaatgggaaccgccatttctgtagccag
acaatcattggaagctgttgaggatttgcacaacattggattcttgcaccgagacattaa
accaggaaattataccatcggacggaaggagatgcacgaattgagaaaggtctacatgct
cgatttcggaatggcacgcaagtttgcccgtgaagacggaactcttcgcaatccacgtgc
tcgtgctggattccgtggaacggtgaagtatgctccattggcttgccatattcaacgtga
gcagtgtcgcaaggatgacattgaaagttggctctacatggtcgttgaaatgacatgtgg
acgtcttccctggcgtaatctgactgaaagtgatgatgtgggagtgttcaagaaggaatg
taaaacgactcgtcttaggtgtctgtttggaggttgtccgcgtgaattcactgaagtttt
cccgattcttgacaaaggaaagttcttcgatgctccggagtacacgaccatctacgagct
ccttgaaaagg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TCTCCGCAAAACTGCTCCATTCAAC 161 609 333 Antisense
AACCGCCATTTCTGTAGCCAGACAA 509 145 372 Antisense
GAATGGCACGCAAGTTTGCCCGTGA 462 333 521 Antisense
GAAAGTTGGCTCTACATGGTCGTTG 93 359 655 Antisense
AAATGACATGTGGACGTCTTCCCTG 40 121 680 Antisense
TCTTCCCTGGCGTAATCTGACTGAA 683 617 696 Antisense
AACGACTCGTCTTAGGTGTCTGTTT 347 145 756 Antisense
GAGGTTGTCCGCGTGAATTCACTGA 500 403 782 Antisense
GAAGTTTTCCCGATTCTTGACAAAG 316 337 805 Antisense
AGTTCTTCGATGCTCCGGAGTACAC 127 65 833 Antisense
ACCATCTACGAGCTCCTTGAAAAGG 606 85 859 Antisense
Sequence Source Affymetrix Proprietary Database