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[190620_s_at] aldehyde dehydrogenase

Description T08B1.3 /REP_DB=WormBase Gene ID /WP=CE13415 /TR=O44555 /GB=AAB94178.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=aldehyde dehydrogenase
Cluster 6grp_highest_10_10 > 63      6grp_high1_10_10 > 03      4grp_highest_8_8 > 40      4grp_high_8_8 > 50      6grp_highest_nonorm > 22      6grp_total > 35      4grp_total > 53      6grp_highest_sub > Cu      6grp_cgc > 34      6grp_high1_sub > De      6grp_cgc_sub > Cu      6grp_total_sub > Cup      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 990
1 2 3 4 range
A 1333.1
(3)
P 		931.3
(0.4)
P 		888.4
(0.2)
P 		391.9
(-3)
P 		941
B 1296.4
(3)
P 		1069.2
(1.3)
P 		958.6
(0.5)
P 		473.1
(-3)
P 		823
C 1264.3
(3)
P 		1076.5
(1.8)
P 		984.7
(1.2)
P 		342.7
(-3)
P 		922
avr 1297.9
(3) 		1025.7
(1.2) 		943.9
(0.6) 		402.6
(-3) 		895

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1610
1 2 3 4 5 6 range
A 2123.4
(2.5)
P 		2262.3
(3)
P 		1711.2
(0.9)
P 		827.4
(-2.3)
P 		652.6
(-3)
P 		1265.8
(-0.7)
P 		1610
B 1841.7
(2)
P 		2076.4
(3)
P 		2015
(2.7)
P 		800.9
(-2.5)
P 		683.4
(-3)
P 		1203.9
(-0.8)
P 		1393
C 1797.6
(1.9)
P 		2024
(3)
P 		2033
(3)
P 		822.8
(-2.5)
P 		716.4
(-3)
P 		1300.6
(-0.3)
P 		1317
avr 1920.9
(2.2) 		2120.9
(3) 		1919.7
(2.2) 		817
(-2.4) 		684.1
(-3) 		1256.8
(-0.6) 		1437
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 428
1 2 3 4 range
A 485.4
(3)
P 		202.2
(-1)
P 		232.2
(-0.5)
P 		57.4
(-3)
P 		428
B 413.4
(3)
P 		264.1
(0.1)
P 		222.1
(-0.7)
P 		100.8
(-3)
P 		313
C 418.5
(3)
P 		309.5
(1.2)
P 		343.2
(1.7)
P 		57.8
(-3)
P 		361
avr 439.1
(3) 		258.6
(0) 		265.8
(0.2) 		72
(-3) 		367

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 639
1 2 3 4 5 6 range
A 391.4
(-1.1)
P 		804.6
(3)
P 		372.7
(-1.3)
P 		209.9
(-2.9)
P 		196.9
(-3)
P 		308.2
(-1.9)
P 		608
B 640.8
(2.4)
P 		691.2
(3)
P 		489.3
(0.5)
P 		212.1
(-3)
P 		277.6
(-2.2)
P 		448.9
(-0)
P 		479
C 666.3
(3)
P 		617.6
(2.4)
P 		517.4
(1.2)
P 		165.5
(-3)
P 		231.8
(-2.2)
P 		435.4
(0.2)
P 		501
avr 566.2
(1.4) 		704.5
(3) 		459.8
(0.1) 		195.8
(-3) 		235.4
(-2.5) 		397.5
(-0.6) 		509
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 190620_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.14910
Sequence Type Exemplar sequence
Representative Public ID T08B1.3 NCBI
Target Description T08B1.3 /REP_DB=WormBase Gene ID /WP=CE13415 /TR=O44555 /GB=AAB94178.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=aldehyde dehydrogenase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_071144(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_071144 NCBI Caenorhabditis elegans ALdehyde deHydrogenase family member (alh-5) (alh-5) mRNA, complete cds. 11/11 None
T08B1.3 ENSEMBL cdna:known chromosome:CEL140:V:1995939:1999409:-1 gene:T08B1.3 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:1995998-1999406(-) 100.0 100.0
Public Domain and Genome References
Gene Title aldehyde dehydrogenase
Gene Symbol alh-5
Ensembl T08B1.3
Entrez Gene 178680 Entrez gene
SwissProt O44555 EMBL-EBI
WormBase CE13415 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:17732_AT aldehyde dehydrogenase (ALDH3) at
ATH1-121501:253237_AT aldehyde dehydrogenase (ALDH3) at
CANINE_2:CFAAFFX.27784.1.S1_AT similar to aldehyde dehydrogenase 3 family, member A1 cfa
CANINE_2:CFAAFFX.27784.1.S1_S_AT similar to aldehyde dehydrogenase 3 family, member A1 cfa
HG-U95AV2:40031_AT aldehyde dehydrogenase 3 family, memberA1 hs
HG-U133_PLUS_2:205623_AT aldehyde dehydrogenase 3 family, memberA1 hs
HG-U133A:205623_AT aldehyde dehydrogenase 3 family, memberA1 hs
HG-FOCUS:205623_AT aldehyde dehydrogenase 3 family, memberA1 hs
HG-U133A_2:205623_AT aldehyde dehydrogenase 3 family, memberA1 hs
HU35KSUBC:RC_AA069024_S_AT aldehyde dehydrogenase 3 family, memberA1 hs
HUGENEFL:M74542_AT aldehyde dehydrogenase 3 family, memberA1 hs
U133_X3P:G4502034_3P_AT aldehyde dehydrogenase 3 family, memberA1 hs
MOUSE430_2:1418752_AT aldehyde dehydrogenase family 3, subfamily A1 mm
MOE430A:1418752_AT aldehyde dehydrogenase family 3, subfamily A1 mm
MOUSE430A_2:1418752_AT aldehyde dehydrogenase family 3, subfamily A1 mm
MU11KSUBA:U12785_S_AT aldehyde dehydrogenase family 3, subfamily A1 mm
MG-U74AV2:99548_AT aldehyde dehydrogenase family 3, subfamily A1 mm
MG-U74AV2:162331_F_AT aldehyde dehydrogenase family 3, subfamily A1 mm
RG-U34A:J03637_AT aldehyde dehydrogenase family 3, member A1 rn
RAE230A:1368130_AT aldehyde dehydrogenase family 3, member A1 rn
RAT230_2:1368130_AT aldehyde dehydrogenase family 3, member A1 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
8152 metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
16491 oxidoreductase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB94178 Aldehyde dehydrogenase protein 5 [Caenorhabditis elegans] ref|NP_503545.1| ALdehyde deHydrogenase family member (alh-5) [Caenorhabditis elegans] 0.0
blast NP_504634 ALdehyde deHydrogenase family member (alh-4) [Caenorhabditis elegans] gb|AAO26003.1| Aldehyde dehydrogenase protein 4, isoform c [Caenorhabditis elegans] 0.0
blast NP_741554 ALdehyde deHydrogenase family member (alh-4) [Caenorhabditis elegans] gb|AAM45357.1| Aldehyde dehydrogenase protein 4, isoform b [Caenorhabditis elegans] 0.0
Protein Domains
Database ID Description E-Value
scop a.4.1.Homeodomain All alpha proteins; DNA/RNA-binding 3-helical bundle; Homeodomain-like; Homeodomain 0.829999983310699
Pfam IPR002086 EMBL-EBI Aldehyde dehydrogenase 6.2E-55
Sequence
Target Sequence 
>C. ELEGANS:190620_S_AT
tgaattgtgggcagacctgtctcgcgccggattacattttggttagcagtgccacaaaac
caaagttcgtcgctgcgatccaaaaatgcttaaaagagttctacggcggaaatgccaagg
agagcaaagactactccagagtcatcaatcagagacattttgaccgcatatccgcacttc
tggatgaatcgaagggagtcgtgcttgctggaaatgaagaatcccgtgatcgctcggatc
gtttcattccaccaacagtccttgacgtcgaaaaaacagatccatttatgcatgatgaaa
tttttgggccagttctgccaattatcactgtcaaaaacctctgcgaatccattgatttta
taaataaaggcgagaaaccattggctgcctacattttcaccaaggatgaagccaaagttc
agagattcctaaatgaaactacaagtggtggtgtaactgttaatgacgtcattatgcatg
ttgctgttataaccctgccattcggaggagtcggagtatccggaatgggacggtaccgtg
gaaagttcggattcgacaccttcac

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TGAATTGTGGGCAGACCTGTCTCGC 263 575 725 Antisense
TCTCGCGCCGGATTACATTTTGGTT 499 609 744 Antisense
AAACCAAAGTTCGTCGCTGCGATCC 594 125 781 Antisense
ATCGAAGGGAGTCGTGCTTGCTGGA 171 35 912 Antisense
GTGATCGCTCGGATCGTTTCATTCC 562 483 950 Antisense
TCCACCAACAGTCCTTGACGTCGAA 524 587 972 Antisense
GGGCCAGTTCTGCCAATTATCACTG 35 493 1030 Antisense
AAAACCTCTGCGAATCCATTGATTT 245 131 1058 Antisense
GAAACCATTGGCTGCCTACATTTTC 149 359 1098 Antisense
ATGTTGCTGTTATAACCCTGCCATT 398 47 1202 Antisense
GAAAGTTCGGATTCGACACCTTCAC 515 359 1265 Antisense
Sequence Source Affymetrix Proprietary Database