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[190619_at] cathepsin-like protease

Description C15C8.3 /REP_DB=WormBase Gene ID /WP=CE05287 /TR=Q18020 /GB=CAA99777.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=cathepsin-like protease
Cluster 6grp_highest_10_10 > 60      6grp_high1_10_10 > 06      4grp_highest_8_8 > 16      4grp_high_8_8 > 52      6grp_highest_nonorm > 04      6grp_total > 07      4grp_total > 59      6grp_highest_sub > De      6grp_high1_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 16542
1 2 3 4 range
A 11013.2
(0.9)
P 		16658.3
(3)
P 		16773.8
(3)
P 		231.7
(-3)
P 		16542
B 11960.9
(1.5)
P 		15203.8
(2.8)
P 		15715.9
(3)
P 		352.1
(-3)
P 		15364
C 10360.4
(1.2)
P 		14478.7
(3)
P 		14488.3
(3)
P 		351.7
(-3)
P 		14137
avr 11111.5
(1.2) 		15446.9
(2.9) 		15659.3
(3) 		311.8
(-3) 		15348

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 10069
1 2 3 4 5 6 range
A 11060.8
(3)
P 		3803.1
(-1.4)
P 		3126.8
(-1.8)
P 		2875.2
(-2)
P 		1639.5
(-2.7)
P 		1151.7
(-3)
P 		9909
B 8763.9
(3)
P 		3442.6
(-1.1)
P 		2674.9
(-1.7)
P 		2397.9
(-1.9)
P 		1907.6
(-2.3)
P 		991.7
(-3)
P 		7772
C 8567.5
(3)
P 		3368.1
(-1.2)
P 		3864.8
(-0.8)
P 		2723.1
(-1.7)
P 		1943.7
(-2.3)
P 		1060
(-3)
P 		7508
avr 9464.1
(3) 		3537.9
(-1.2) 		3222.2
(-1.5) 		2665.4
(-1.9) 		1830.3
(-2.5) 		1067.8
(-3) 		8396
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 5016
1 2 3 4 range
A 4009.9
(2.5)
P 		3616.1
(1.9)
P 		4385
(3)
P 		33.9
(-3)
P 		4351
B 3814.2
(3)
P 		3755
(2.9)
P 		3641.7
(2.7)
P 		75
(-3)
P 		3739
C 3429.6
(1.1)
P 		4162.7
(1.9)
P 		5049.6
(3)
P 		59.3
(-3)
P 		4990
avr 3751.2
(2.2) 		3844.6
(2.3) 		4358.8
(3) 		56.1
(-3) 		4303

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 2895
1 2 3 4 5 6 range
A 2039
(3)
P 		1352.6
(0.7)
P 		681
(-1.6)
P 		729.2
(-1.5)
P 		494.7
(-2.3)
P 		280.4
(-3)
P 		1759
B 3049.4
(3)
P 		1145.9
(-1.3)
P 		649.5
(-2.4)
P 		635.1
(-2.4)
P 		775
(-2.1)
P 		369.8
(-3)
P 		2680
C 3175.6
(3)
P 		1027.7
(-1.6)
P 		983.7
(-1.7)
P 		547.6
(-2.6)
P 		628.9
(-2.4)
P 		354.9
(-3)
P 		2821
avr 2754.7
(3) 		1175.4
(-0.9) 		771.4
(-1.9) 		637.3
(-2.3) 		632.9
(-2.3) 		335
(-3) 		2420
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190619_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.14410
Sequence Type Exemplar sequence
Representative Public ID C15C8.3 NCBI
Target Description C15C8.3 /REP_DB=WormBase Gene ID /WP=CE05287 /TR=Q18020 /GB=CAA99777.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=cathepsin-like protease
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073784(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073784 NCBI Caenorhabditis elegans C15C8.3 (C15C8.3) mRNA, complete cds. 11/11 None
SNAP00000030242 ENSEMBL cdna:SNAP chromosome:CEL140:V:12744660:12746697:1 11/11 None
GENEFINDER00000030256 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:12744660:12746697:1 11/11 None
C15C8.3 ENSEMBL cdna:known chromosome:CEL140:V:12744631:12746751:1 gene:C15C8.3 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:12744659-12746697(+) 100.0 100.0
Public Domain and Genome References
Gene Title cathepsin-like protease
Ensembl C15C8.3
Entrez Gene 182635 Entrez gene
SwissProt Q18020 EMBL-EBI
WormBase CE05287 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4194 pepsin A activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA99777 Hypothetical protein C15C8.3 [Caenorhabditis elegans] ref|NP_506185.1| C15C8.3 [Caenorhabditis elegans] 0.0
blast CAE63983 Hypothetical protein CBG08575 [Caenorhabditis briggsae] 0.0
blast CAE70423 Hypothetical protein CBG16997 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR001461 EMBL-EBI Peptidase A1, pepsin 4.4E-70
Sequence
Target Sequence 
>C. ELEGANS:190619_AT
cctgctctagccgtaaaccaacaaactccaccattgttcaatttgatgaatcaaggaaaa
cttgatcaaccatactttgtcgtatatcttgccaacattggtccaacttcccaaatcaat
ggaggagcattcaccgttggaggtctcgatacaactcattgtagttctaatgtcgactgg
gttccactatccactcaaactttctggcagtttaagctcggaggagtatcatctgggtca
tacagtcaagctccaaactctggatggcaagcagctgctgatacagctgcatcattcatc
ggagcaccaaagagtgttgttaccagtcttgccaaggcagttggagccacatatgttcca
cttacgggtgcattcttcatggattgtgacgctgttgtcccagatattgtattcacaatt
aacggaaaaacatataatatgccatcaacatcattcgttgtatctgctggacctgggcca
tgcatgtttgcattttatgagttaactgctggaggattctatccagcttggatgctcgga
ccaccttttatgcgtgcctattgccacgtacat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CCTGCTCTAGCCGTAAACCAACAAA 314 267 685 Antisense
GAGCATTCACCGTTGGAGGTCTCGA 433 389 809 Antisense
TAATGTCGACTGGGTTCCACTATCC 163 637 852 Antisense
CTATCCACTCAAACTTTCTGGCAGT 85 225 871 Antisense
AGCTGCATCATTCATCGGAGCACCA 121 81 969 Antisense
TGTTGTTACCAGTCTTGCCAAGGCA 684 561 999 Antisense
AGCCACATATGTTCCACTTACGGGT 92 85 1029 Antisense
GATTGTGACGCTGTTGTCCCAGATA 499 435 1066 Antisense
TCATTCGTTGTATCTGCTGGACCTG 411 619 1135 Antisense
TATCCAGCTTGGATGCTCGGACCAC 468 657 1204 Antisense
TATGCGTGCCTATTGCCACGTACAT 598 657 1233 Antisense
Sequence Source Affymetrix Proprietary Database