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[190611_s_at] serine/threonine kinase

Description F22D6.5 /REP_DB=WormBase Gene ID /WP=CE05686 /TR=Q19727 /GB=CAA95814.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster 6grp_highest_10_10 > 65      6grp_high1_10_10 > 56      4grp_highest_8_8 > 44      4grp_high_8_8 > 16      6grp_highest_nonorm > 83      6grp_total > 57      4grp_total > 31      6grp_cgc > 37      6grp_high1_sub > Cu      6grp_cgc_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 548
1 2 3 4 range
A 764.3
(3)
P 		344.4
(-3)
P 		341.7
(-3)
P 		563.4
(0.1)
P 		423
B 821.2
(3)
P 		331.4
(-2.4)
P 		273.4
(-3)
P 		474.3
(-0.8)
P 		548
C 714.8
(3)
P 		314
(-3)
P 		459.9
(-0.8)
P 		612.4
(1.5)
P 		401
avr 766.8
(3) 		329.9
(-3) 		358.3
(-2.6) 		550
(0) 		437

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 449
1 2 3 4 5 6 range
A 503.5
(0.2)
P 		550.8
(1)
P 		447.1
(-0.8)
P 		530.9
(0.6)
P 		323.1
(-3)
P 		666.6
(3)
P 		344
B 565.9
(-0)
P 		444.8
(-2.1)
P 		392.3
(-3)
P 		475.5
(-1.6)
P 		509.9
(-1)
P 		745.1
(3)
P 		353
C 477.6
(-1.2)
P 		567.9
(0.1)
P 		603.8
(0.6)
P 		482
(-1.1)
P 		350.6
(-3)
P 		772.2
(3)
P 		422
avr 515.7
(-0.8) 		521.2
(-0.7) 		481.1
(-1.4) 		496.1
(-1.2) 		394.5
(-3) 		728
(3) 		334
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 215
1 2 3 4 range
A 278.3
(3)
P 		74.8
(-3)
P 		89.3
(-2.6)
P 		82.5
(-2.8)
P 		204
B 261.9
(3)
P 		81.8
(-2.4)
P 		63.4
(-3)
P 		101.1
(-1.9)
P 		199
C 236.6
(3)
P 		90.3
(-3)
P 		160.3
(-0.1)
P 		103.3
(-2.5)
P 		146
avr 258.9
(3) 		82.3
(-3) 		104.3
(-2.3) 		95.6
(-2.5) 		177

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 185
1 2 3 4 5 6 range
A 92.8
(-3)
P 		195.9
(3)
P 		97.4
(-2.7)
P 		134.6
(-0.6)
P 		97.5
(-2.7)
P 		162.3
(1)
P 		103
B 196.9
(0.3)
P 		148
(-1.3)
P 		95.3
(-3)
P 		125.9
(-2)
P 		207.2
(0.7)
P 		277.8
(3)
P 		183
C 177
(-0)
P 		173.3
(-0.2)
P 		153.7
(-0.9)
P 		96.9
(-3)
P 		113.4
(-2.4)
P 		258.5
(3)
P 		162
avr 155.6
(-1) 		172.4
(-0.1) 		115.5
(-3) 		119.1
(-2.8) 		139.4
(-1.8) 		232.9
(3) 		117
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 190611_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.1410
Sequence Type Exemplar sequence
Representative Public ID F22D6.5 NCBI
Target Description F22D6.5 /REP_DB=WormBase Gene ID /WP=CE05686 /TR=Q19727 /GB=CAA95814.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059607(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_059607 NCBI Caenorhabditis elegans yeast PRP (splicing factor) related family member (prp-4) (prp-4) mRNA, complete cds. 11/11 None
SNAP00000037651 ENSEMBL cdna:SNAP chromosome:CEL140:I:7099593:7102643:-1 11/11 None
GENEFINDER00000037660 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:7099593:7102643:-1 11/11 None
F22D6.5 ENSEMBL cdna:known chromosome:CEL140:I:7099467:7102664:-1 gene:F22D6.5 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:7099523-7102574(-) 96.35 100.0
Public Domain and Genome References
Gene Title serine/threonine kinase
Gene Symbol prp-4
Ensembl F22D6.5
Entrez Gene 172443 Entrez gene
SwissProt Q19727 EMBL-EBI
WormBase CE05686 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:256995_AT protein kinase family protein at
CANINE:1595908_S_AT similar to serine/threonine-protein kinase PRP4K cfa
CANINE:1594994_AT similar to serine/threonine-protein kinase PRP4K cfa
CANINE:1591415_AT similar to serine/threonine-protein kinase PRP4K cfa
CANINE_2:CFA.1509.1.A1_S_AT similar to serine/threonine-protein kinase PRP4K cfa
CANINE_2:CFA.1509.2.A1_AT similar to serine/threonine-protein kinase PRP4K cfa
CANINE_2:CFA.1509.3.A1_S_AT similar to serine/threonine-protein kinase PRP4K cfa
CANINE_2:CFAAFFX.14798.1.S1_AT similar to serine/threonine-protein kinase PRP4K cfa
CANINE_2:CFAAFFX.14799.1.S1_AT similar to serine/threonine-protein kinase PRP4K cfa
CANINE_2:CFAAFFX.14799.1.S1_S_AT similar to serine/threonine-protein kinase PRP4K cfa
DROSGENOME1:151999_AT dm
DROSOPHILA_2:1640619_AT dm
CHICKEN:GGAAFFX.11896.1.S1_S_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) gga
CHICKEN:GGAAFFX.11896.1.A1_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) gga
HG-U95AV2:825_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) hs
HC-G110:825_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) hs
HG-U133_PLUS_2:211090_S_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) hs
HG-U133A:211090_S_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) hs
HG-U133A_2:211090_S_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) hs
HG-FOCUS:202127_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) hs
HG-U133A_2:202127_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) hs
HG-U133_PLUS_2:202127_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) hs
HG-U133A:202127_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) hs
HU35KSUBC:RC_AA454108_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) hs
HUGENEFL:U48736_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) hs
HG-U133A:202126_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) hs
HG-U133A_2:202126_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) hs
HG-U133_PLUS_2:202126_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) hs
U133_X3P:G405748_3P_S_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) hs
U133_X3P:HS.198891.0.S3_3P_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) hs
U133_X3P:HS.198891.0.S2_3P_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) hs
HG-U95AV2:32784_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) hs
HG-U95C:52171_R_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) hs
MOE430A:1451909_A_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) mm
MOUSE430_2:1451909_A_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) mm
MOUSE430A_2:1451909_A_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) mm
MOUSE430A_2:1436427_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) mm
MOE430A:1436427_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) mm
MOUSE430_2:1436427_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) mm
MU11KSUBA:U48737_S_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) mm
MG-U74AV2:102017_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) mm
MG-U74CV2:130416_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) mm
MG-U74BV2:165198_F_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) mm
MG-U74CV2:167926_F_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) mm
MG-U74CV2:167925_R_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) mm
MOE430A:1451732_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) mm
MOUSE430A_2:1451732_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) mm
MOUSE430_2:1451732_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) mm
MOE430A:1455696_A_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) mm
MOUSE430A_2:1455696_A_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) mm
MOUSE430_2:1455696_A_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) mm
MOE430A:1425497_A_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) mm
MOUSE430A_2:1425497_A_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) mm
MOUSE430_2:1425497_A_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) mm
MOE430A:1425498_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) mm
MOUSE430A_2:1425498_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) mm
MOUSE430_2:1425498_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) mm
MU19KSUBB:TC33039_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) (Prpf4b), mRNA mm
MU19KSUBB:TC33742_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) (Prpf4b), mRNA mm
RG-U34B:RC_AA955630_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) (predicted) rn
RAE230A:1376010_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) (predicted) rn
RAT230_2:1376010_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) (predicted) rn
RAE230B:1397203_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) (predicted) rn
RAT230_2:1397203_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) (predicted) rn
RAE230B:1382646_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) (predicted) rn
RAT230_2:1382646_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) (predicted) rn
RAE230B:1382910_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) (predicted) rn
RAT230_2:1382910_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) (predicted) rn
RG-U34C:RC_AI072237_AT PRP4 pre-mRNA processing factor 4 homolog B (yeast) (predicted) rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA95814 Hypothetical protein F22D6.5 [Caenorhabditis elegans] ref|NP_492008.1| yeast PRP (splicing factor) related family member (prp-4) [Caenorhabditis elegans] 0.0
blast CAE73097 Hypothetical protein CBG20476 [Caenorhabditis briggsae] 0.0
blast EAA09718 ENSANGP00000013112 [Anopheles gambiae str. PEST] ref|XP_314361.2| ENSANGP00000013112 [Anopheles gambiae str. PEST] 1.0E-124
Protein Families
Method ID Description E-Value
hanks 3.1.3 CMCG Group; CMGC I Cyclin-dependent (CDKs) and close relatives; Cdk3 3.0E-21
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 5.8E-47
Sequence
Target Sequence 
>C. ELEGANS:190611_S_AT
ttgtgattttggttctgctggtcgcgtcaatgaacaagaattggccccatacttggtctc
tagattttatcgtgcaccagaaattatgctcggagtccgtcatgactatgcaattgacct
ctggtccgttgcagttactctctatgaagtttacactggaaaaatcatgttcccaggacg
aaccaataatcatatgttgaaattgttcactgatgtcaaaggaaaatatcccaacaaatt
ggttcgaaaatcgcaattcaaagatactcactttgatgtaaactgtaatcttttgtatca
agaagttgacaaagttacagaaagaaacaagattactgttcttgcaaatttgaaaccgac
acgcgatttggaatcagaattgattgccgggcaacgtttgagcagagaccaaatggatca
gatacaagcgttccgaactttgctcgatg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTGTGATTTTGGTTCTGCTGGTCGC 456 707 1809 Antisense
TCTGCTGGTCGCGTCAATGAACAAG 601 609 1822 Antisense
AAGAATTGGCCCCATACTTGGTCTC 454 149 1844 Antisense
GTCTCTAGATTTTATCGTGCACCAG 661 469 1864 Antisense
GCTCGGAGTCCGTCATGACTATGCA 218 299 1896 Antisense
TGCAATTGACCTCTGGTCCGTTGCA 601 575 1917 Antisense
TCCGTTGCAGTTACTCTCTATGAAG 142 595 1933 Antisense
AATCATGTTCCCAGGACGAACCAAT 632 165 1971 Antisense
GAAACCGACACGCGATTTGGAATCA 492 357 2160 Antisense
GATTGCCGGGCAACGTTTGAGCAGA 630 433 2190 Antisense
CAAGCGTTCCGAACTTTGCTCGATG 256 185 2233 Antisense
Sequence Source Affymetrix Proprietary Database