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[190600_s_at] 1r20 protein (human)

Description C05B5.7 /REP_DB=WormBase Gene ID /WP=CE27794 /TR=SW:P34295 /GB=CAA83595.2 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=1r20 protein (human)
Cluster 6grp_highest_10_10 > 61      6grp_high1_10_10 > 26      4grp_highest_8_8 > 53      4grp_high_8_8 > 09      6grp_highest_nonorm > 90      6grp_total > 26      4grp_total > 23      6grp_highest_sub > De      6grp_cgc > 14      6grp_high1_sub > De      6grp_cgc_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 238
1 2 3 4 range
A 320
(3)
P 		82.2
(-3)
P 		99.5
(-2.6)
P 		234.7
(0.8)
P 		238
B 269.8
(3)
P 		130.7
(-1.6)
P 		89
(-3)
P 		211.3
(1.1)
P 		181
C 300.9
(3)
P 		139.2
(-2.2)
P 		116
(-3)
P 		284.3
(2.5)
P 		185
avr 296.9
(3) 		117.4
(-2.5) 		101.5
(-3) 		243.4
(1.4) 		195

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 236
1 2 3 4 5 6 range
A 231.4
(3)
P 		178
(0.9)
P 		164.2
(0.4)
P 		78.2
(-3)
P 		87.6
(-2.6)
P 		109.7
(-1.8)
P 		153
B 304.3
(3)
P 		210.3
(0.1)
P 		140.7
(-2)
P 		139.2
(-2.1)
P 		109.7
(-3)
P 		139.8
(-2.1)
P 		195
C 216.4
(3)
P 		200.7
(2.4)
P 		70.8
(-2.9)
P 		85.8
(-2.3)
P 		67.9
(-3)
P 		134.3
(-0.3)
P 		149
avr 250.7
(3) 		196.3
(1) 		125.2
(-1.6) 		101.1
(-2.5) 		88.4
(-3) 		127.9
(-1.5) 		162
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 99
1 2 3 4 range
A 116.5
(3)
P 		17.9
(-3)
P 		26
(-2.5)
P 		34.4
(-2)
P 		99
B 86.1
(3)
P 		32.3
(-1.9)
P 		20.6
(-3)
P 		45
(-0.8)
P 		66
C 99.6
(3)
P 		40
(-3)
P 		40.4
(-3)
P 		47.9
(-2.2)
P 		60
avr 100.7
(3) 		30.1
(-2.9) 		29
(-3) 		42.4
(-1.9) 		72

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 89
1 2 3 4 5 6 range
A 42.7
(0.2)
P 		63.3
(3)
P 		35.8
(-0.8)
P 		19.8
(-3)
P 		26.4
(-2.1)
P 		26.7
(-2)
P 		44
B 105.9
(3)
P 		70
(-0)
P 		34.2
(-3)
P 		36.9
(-2.8)
P 		44.6
(-2.1)
P 		52.1
(-1.5)
P 		72
C 80.2
(3)
P 		61.2
(1.2)
P 		18
(-2.9)
P 		17.3
(-3)
P 		22
(-2.6)
P 		45
(-0.4)
P 		63
avr 76.3
(3) 		64.8
(1.7) 		29.3
(-2.5) 		24.7
(-3) 		31
(-2.3) 		41.3
(-1.1) 		52
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 190600_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.7670
Sequence Type Exemplar sequence
Representative Public ID C05B5.7 NCBI
Target Description C05B5.7 /REP_DB=WormBase Gene ID /WP=CE27794 /TR=SW:P34295 /GB=CAA83595.2 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=1r20 protein (human)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_066820(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_066820 NCBI Caenorhabditis elegans Regulator of G protein Signaling family member (rgs-1) (rgs-1) mRNA, complete cds. 11/11 A 
GENEFINDER00000026758 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:10010733:10016890:-1 11/11 None
SNAP00000026750 ENSEMBL cdna:SNAP chromosome:CEL140:III:10014483:10016415:-1 11/11 None
C05B5.7 ENSEMBL cdna:known chromosome:CEL140:III:10014082:10016448:-1 gene:C05B5.7 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:10015522-10016420(-) 78.43 100.0
Public Domain and Genome References
Gene Title 1r20 protein (human)
Gene Symbol rgs-1
Ensembl C05B5.7
Entrez Gene 176415 Entrez gene
SwissProt P34295 EMBL-EBI
WormBase CE27794 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.11323.1.S1_S_AT similar to regulator of G-protein signalling 20 isoform b cfa
CHICKEN:GGA.352.1.S1_AT regulator of G-protein signalling 20 gga
HG-U133A:210138_AT regulator of G-protein signalling 20 hs
HG-U133_PLUS_2:210138_AT regulator of G-protein signalling 20 hs
HG-FOCUS:210138_AT regulator of G-protein signalling 20 hs
HG-U133A_2:210138_AT regulator of G-protein signalling 20 hs
HU35KSUBC:RC_N49767_AT regulator of G-protein signalling 20 hs
HU35KSUBD:RC_AA450087_AT regulator of G-protein signalling 20 hs
U133_X3P:G3523159_3P_AT regulator of G-protein signalling 20 hs
U133_X3P:HS2.402165.1.S1_3P_S_AT regulator of G-protein signalling 20 hs
HG-U133_PLUS_2:1569303_S_AT regulator of G-protein signalling 20 hs
HG-U95AV2:41086_AT regulator of G-protein signalling 20 hs
HG-U95C:63193_AT Regulator of G-protein signalling 20 hs
MOE430A:1421493_A_AT regulator of G-protein signaling 20 mm
MOUSE430_2:1421493_A_AT regulator of G-protein signaling 20 mm
MOUSE430A_2:1421493_A_AT regulator of G-protein signaling 20 mm
MOUSE430_2:1446199_AT regulator of G-protein signaling 20 mm
MOE430B:1446199_AT regulator of G-protein signaling 20 mm
MOE430B:1443694_AT regulator of G-protein signaling 20 mm
MOUSE430_2:1443694_AT regulator of G-protein signaling 20 mm
RAE230B:1396547_AT Similar to regulator of G-protein signaling Z1 rn
RAT230_2:1396547_AT Similar to regulator of G-protein signaling Z1 rn
RAE230B:1396870_AT Similar to regulator of G-protein signaling Z1 rn
RAT230_2:1396870_AT Similar to regulator of G-protein signaling Z1 rn
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
4871 signal transducer activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast G88571 protein C05B5.7 [imported] - Caenorhabditis elegans 1.0E-126
blast S43576 C05B5.7 protein (clone C05B5) - Caenorhabditis elegans 1.0E-124
blast CAA83595 Hypothetical protein C05B5.7 [Caenorhabditis elegans] ref|NP_499221.1| Regulator of G protein Signaling family member (rgs-1) [Caenorhabditis elegans] gb|AAF33236.1| RGS-1 [Caenorhabditis elegans] sp|P34295|RGS1_CAEEL Regulator of G protein signaling rgs-1 1.0E-103
blast G88571 protein C05B5.7 [imported] - Caenorhabditis elegans 1.0E-103
blast CAA83595 Hypothetical protein C05B5.7 [Caenorhabditis elegans] ref|NP_499221.1| Regulator of G protein Signaling family member (rgs-1) [Caenorhabditis elegans] gb|AAF33236.1| RGS-1 [Caenorhabditis elegans] sp|P34295|RGS1_CAEEL Regulator of G protein signaling rgs-1 1.0E-102
blast S43576 C05B5.7 protein (clone C05B5) - Caenorhabditis elegans 1.0E-101
blast CAA83595 Hypothetical protein C05B5.7 [Caenorhabditis elegans] ref|NP_499221.1| Regulator of G protein Signaling family member (rgs-1) [Caenorhabditis elegans] gb|AAF33236.1| RGS-1 [Caenorhabditis elegans] sp|P34295|RGS1_CAEEL Regulator of G protein signaling rgs-1 1.0E-101
Protein Domains
Database ID Description E-Value
Pfam IPR000342 EMBL-EBI Regulator of G protein 1.0E-55
Pfam IPR000342 EMBL-EBI Regulator of G protein 1.0E-55
Pfam IPR000342 EMBL-EBI Regulator of G protein 1.0E-55
Trans Membrane
ID Number Of Domains Domain Boundaries
GENEFINDER00000026758 3 13-38,53-75,96-118
Sequence
Target Sequence 
>C. ELEGANS:190600_S_AT
atgagcttcaagtctggccagaaatgttttgccgaatttttaaaaagtgagtattcggat
gagaacatcttattttggcaagcctgtgaagagctgaaacgggaaaagaattctgaaaaa
atggaagaaaaagcacgtatcatctatgaagatttcatctcaatattatcaccaaaagaa
gtttcactggattcaaaagttcgagaaattgtcaacactaacatgtcccgtccaacacag
aatacattcgaagatgctcaacatcaaatctatcagctgatggcaagagacagttatcca
agattccttacctccattttctacagggaaactctagcttcttttggaataactgaaatg
gatattggaggagacgaagagaaggaacgagagcaaagagcggaacgtgcacgtttgaat
gttccagctac

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATGAGCTTCAAGTCTGGCCAGAAAT 68 43 148 Antisense
GGCCAGAAATGTTTTGCCGAATTTT 352 541 163 Antisense
GAACATCTTATTTTGGCAAGCCTGT 378 351 210 Antisense
ATTGTCAACACTAACATGTCCCGTC 543 3 355 Antisense
GTCCCGTCCAACACAGAATACATTC 56 475 372 Antisense
GCTCAACATCAAATCTATCAGCTGA 666 301 403 Antisense
CAGTTATCCAAGATTCCTTACCTCC 410 205 438 Antisense
TCCTTACCTCCATTTTCTACAGGGA 246 591 452 Antisense
ACAGGGAAACTCTAGCTTCTTTTGG 570 105 470 Antisense
AGCAAAGAGCGGAACGTGCACGTTT 267 73 539 Antisense
GTGCACGTTTGAATGTTCCAGCTAC 40 481 554 Antisense
Sequence Source Affymetrix Proprietary Database