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[190596_s_at] serine/threonine kinase

Description ZK930.1 /REP_DB=WormBase Gene ID /WP=CE06671 /TR=Q23669 /GB=CAA94175.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster 6grp_highest_10_10 > 84      6grp_high1_10_10 > 47      4grp_highest_8_8 > 60      4grp_high_8_8 > 26      6grp_highest_nonorm > 75      6grp_total > 47      4grp_total > 38      6grp_highest_sub > Cu      6grp_high1_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 325
1 2 3 4 range
A 1017.9
(2.3)
P 		1057.6
(3)
P 		732.7
(-3)
P 		943.6
(0.9)
P 		325
B 992.9
(3)
P 		830.6
(-2.9)
P 		827
(-3)
P 		903.5
(-0.2)
P 		166
C 1005.1
(3)
P 		805.6
(-3)
P 		892.9
(-0.4)
P 		876.2
(-0.9)
P 		200
avr 1005.3
(3) 		897.9
(-0.4) 		817.5
(-3) 		907.8
(-0.1) 		188

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 403
1 2 3 4 5 6 range
A 954.1
(3)
P 		930.3
(2.4)
P 		853.9
(0.5)
P 		715.3
(-3)
P 		844.5
(0.2)
P 		932.1
(2.4)
P 		239
B 1050.2
(1.6)
P 		959.4
(-0.3)
P 		872.1
(-2)
P 		926
(-0.9)
P 		824.8
(-3)
P 		1118.5
(3)
P 		294
C 894.3
(0.7)
P 		886.6
(0.5)
P 		870.8
(0.2)
P 		729.8
(-3)
P 		838.2
(-0.6)
P 		995.3
(3)
P 		266
avr 966.2
(1.7) 		925.4
(0.6) 		865.6
(-1) 		790.4
(-3) 		835.8
(-1.8) 		1015.3
(3) 		225
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 233
1 2 3 4 range
A 370.6
(3)
P 		229.6
(-0.6)
P 		191.6
(-1.6)
P 		138.1
(-3)
P 		233
B 316.6
(3)
P 		205.2
(-2.3)
P 		191.6
(-3)
P 		192.5
(-3)
P 		125
C 332.7
(3)
P 		231.6
(-0.3)
P 		311.2
(2.3)
P 		147.7
(-3)
P 		185
avr 340
(3) 		222.1
(-0.9) 		231.5
(-0.6) 		159.4
(-3) 		181

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 270
1 2 3 4 5 6 range
A 175.9
(-3)
P 		330.9
(3)
P 		186
(-2.6)
P 		181.4
(-2.8)
P 		254.8
(0.1)
P 		226.9
(-1)
P 		155
B 365.4
(1.5)
P 		319.3
(0.1)
P 		211.8
(-3)
P 		245.3
(-2)
P 		335.1
(0.6)
P 		417.1
(3)
P 		205
C 331.5
(2.9)
P 		270.5
(1)
P 		221.6
(-0.6)
P 		146.8
(-3)
P 		271.2
(1)
P 		333.2
(3)
P 		186
avr 290.9
(1.4) 		306.9
(2.2) 		206.5
(-2.3) 		191.2
(-3) 		287
(1.3) 		325.7
(3) 		135
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 190596_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.2973
Sequence Type Exemplar sequence
Representative Public ID ZK930.1 NCBI
Target Description ZK930.1 /REP_DB=WormBase Gene ID /WP=CE06671 /TR=Q23669 /GB=CAA94175.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_064141(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_064141 NCBI Caenorhabditis elegans ZK930.1 (ZK930.1) mRNA, complete cds. 11/11 None
ZK930.1 ENSEMBL cdna:known chromosome:CEL140:II:11908633:11915749:-1 gene:ZK930.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:11908789-11915746(-) 100.0 100.0
Public Domain and Genome References
Gene Title serine/threonine kinase
Ensembl ZK930.1
Entrez Gene 174827 Entrez gene
SwissProt Q23669 EMBL-EBI
WormBase CE06671 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA94175 Hypothetical protein ZK930.1 [Caenorhabditis elegans] ref|NP_496542.1| ZK930.1 [Caenorhabditis elegans] 0.0
blast CAE59392 Hypothetical protein CBG02750 [Caenorhabditis briggsae] 0.0
blast XP_692535 PREDICTED: similar to phosphoinositide-3-kinase, regulatory subunit 4, p150 [Danio rerio] 2.0E-98
Protein Domains
Database ID Description E-Value
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 7.7E-8
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 0.0029
Pfam IPR000719 EMBL-EBI Protein kinase 0.0017
Pfam IPR000719 EMBL-EBI Protein kinase 4.6E-6
Sequence
Target Sequence 
>C. ELEGANS:190596_S_AT
tgggagtctccacatcagaatacccagccgaacagagtatgggcgaatccagtatcgcgg
caagagtgtcccgaagttttcgttggattctcgatgcatggcgagattagtacctatgaa
ctaagtgctcaacctctacgaaaacgagttttctggactggaggagctccgattttaagt
tatagtgccgcgtcaaacgatgcccggaaacaagattcccttgccactcgatctctatgc
gtttgcgagaagacaggcgttgtctacacaggtgacacacgtggagcaatccgaaaatgg
aatcctacacgagctgtcggctgtgaaatcatctccgccccgccgaaaggacgtaccgcg
tatcgaacgatctttgaggaaaacgacacatcaacagctccatctggagcttcgacagat
ccatttgtaatttatgaacgcaccgtgttggacacagaagccaaggagaatcagaaagtt
gttccgttagattcaaagccatccacctatcaccgtaccccgatcaccgacatgatgctt
ctcaactctgaactgct

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TGGGAGTCTCCACATCAGAATACCC 175 553 3478 Antisense
GGCAAGAGTGTCCCGAAGTTTTCGT 390 531 3536 Antisense
AACTAAGTGCTCAACCTCTACGAAA 259 141 3596 Antisense
TATAGTGCCGCGTCAAACGATGCCC 85 659 3658 Antisense
CCACTCGATCTCTATGCGTTTGCGA 630 273 3701 Antisense
GACAGGCGTTGTCTACACAGGTGAC 245 369 3729 Antisense
TCCTACACGAGCTGTCGGCTGTGAA 149 593 3780 Antisense
GTCGGCTGTGAAATCATCTCCGCCC 84 473 3793 Antisense
GACGTACCGCGTATCGAACGATCTT 236 367 3827 Antisense
TAGATTCAAAGCCATCCACCTATCA 295 653 3965 Antisense
TGATGCTTCTCAACTCTGAACTGCT 207 567 4010 Antisense
Sequence Source Affymetrix Proprietary Database