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[190594_at] ser/thr-protein kinase

Description ZC581.1 /REP_DB=WormBase Gene ID /WP=CE15235 /TR=O01775 /GB=AAB54139.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=ser-thr-protein kinase
Cluster 6grp_highest_10_10 > 28      6grp_high1_10_10 > 71      4grp_highest_8_8 > 14      4grp_high_8_8 > 15      6grp_highest_nonorm > 62      6grp_total > 71      4grp_total > 09      6grp_highest_sub > 04      6grp_high1_sub > 04      6grp_total_sub > Hat      6grp_rule_based > S4      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 429
1 2 3 4 range
A 339
(-3)
P 		406.8
(-2)
P 		463.4
(-1.2)
P 		763.8
(3)
P 		425
B 341
(-3)
P 		394.4
(-2.2)
P 		467.6
(-1.1)
P 		730.6
(3)
P 		390
C 410
(-2.6)
P 		384.1
(-3)
P 		412.7
(-2.6)
P 		768
(3)
P 		384
avr 363.3
(-3) 		395.1
(-2.5) 		447.9
(-1.7) 		754.1
(3) 		391

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 417
1 2 3 4 5 6 range
A 451
(-0.7)
P 		401.3
(-1.9)
P 		524.7
(0.9)
P 		615.7
(3)
P 		551.1
(1.5)
P 		350.5
(-3)
P 		265
B 376.4
(-3)
P 		404.7
(-2.2)
P 		538.5
(1.3)
P 		602.7
(3)
P 		562.4
(1.9)
P 		392.4
(-2.6)
P 		226
C 289.3
(-3)
P 		417.1
(-1.2)
P 		467.3
(-0.4)
P 		706.1
(3)
P 		470.7
(-0.4)
P 		370.6
(-1.8)
P 		417
avr 372.2
(-3) 		407.7
(-2.2) 		510.2
(0.1) 		641.5
(3) 		528.1
(0.5) 		371.2
(-3) 		270
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 67
1 2 3 4 range
A 123.4
(3)
P 		88.3
(-3)
P 		121.1
(2.6)
P 		111.8
(1)
P 		35
B 108.7
(-1.8)
P 		97.4
(-3)
P 		108.3
(-1.9)
P 		155.7
(3)
P 		58
C 135.7
(1.5)
P 		110.4
(-3)
P 		143.8
(3)
P 		129.5
(0.4)
P 		33
avr 122.6
(1.3) 		98.7
(-3) 		124.4
(1.6) 		132.3
(3) 		34

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 145
1 2 3 4 5 6 range
A 83.1
(-3)
P 		142.7
(1.3)
P 		114.3
(-0.8)
P 		156.2
(2.3)
P 		166.3
(3)
P 		85.3
(-2.8)
P 		83
B 131
(-3)
P 		134.7
(-2.8)
P 		130.8
(-3)
P 		159.6
(-1.2)
P 		228.5
(3)
P 		146.3
(-2)
P 		98
C 107.2
(-3)
P 		127.3
(-0.3)
P 		118.9
(-1.4)
P 		142
(1.6)
P 		152.3
(3)
P 		124.1
(-0.8)
P 		45
avr 107.1
(-3) 		134.9
(-0.8) 		121.3
(-1.9) 		152.6
(0.6) 		182.4
(3) 		118.6
(-2.1) 		75
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190594_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.1784
Sequence Type Exemplar sequence
Representative Public ID ZC581.1 NCBI
Target Description ZC581.1 /REP_DB=WormBase Gene ID /WP=CE15235 /TR=O01775 /GB=AAB54139.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=ser-thr-protein kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059513(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_059513 NCBI Caenorhabditis elegans ZC581.1 (ZC581.1) mRNA, complete cds. 11/11 None
GENEFINDER00000015890 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:6671181:6673221:1 11/11 None
SNAP00000015886 ENSEMBL cdna:SNAP chromosome:CEL140:I:6671340:6673221:1 11/11 None
ZC581.1 ENSEMBL cdna:known chromosome:CEL140:I:6671340:6673221:1 gene:ZC581.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:6671268-6673150(+) 100.0 100.0
Public Domain and Genome References
Gene Title ser/thr-protein kinase
Ensembl ZC581.1
Entrez Gene 191199 Entrez gene
SwissProt O01775 EMBL-EBI
WormBase CE15235 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB54139 Hypothetical protein ZC581.1 [Caenorhabditis elegans] ref|NP_491914.1| ZC581.1 [Caenorhabditis elegans] 0.0
blast CAE67255 Hypothetical protein CBG12695 [Caenorhabditis briggsae] 1.0E-129
blast NP_001006906 NIMA (never in mitosis gene a)- related kinase 8 [Xenopus tropicalis] gb|AAH75274.1| NIMA (never in mitosis gene a)- related kinase 8 [Xenopus tropicalis] 2.0E-69
Protein Families
Method ID Description E-Value
hanks 2.1.8 CaMK Group; CaMK I Regulated by Ca2+/CaM and close relatives; DdMLCK 1.0E-65
hanks 2.1.8 CaMK Group; CaMK I Regulated by Ca2+/CaM and close relatives; DdMLCK 3.0E-66
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 1.5E-74
Pfam IPR000719 EMBL-EBI Protein kinase 1.5E-74
Sequence
Target Sequence 
>C. ELEGANS:190594_AT
gaaatctgcagcgtcgactgttattggaactccaaactatttaagccctgaaatttgtga
aagtcgcccgtacaatcaaaaaagtgacatgtggtctttaggatgtgttttgtatgagct
tcttcagcttgaaagagcatttgacggcgaaaatttaccagccattgtaatgaaaatcac
ccggtcaaagcaaaacccgttgggagatcacgtatcaaacgatgtgaagatgttagtgga
aaacttacttaaaacacacacggataagagaccggacgtatcacagctgctttccgatcc
acttgttcttccctatttgatatcaattcattgcgatttgggaagaatcgaacctccacc
gacggataagagaaagccatcagcttcattgagcagtcgacttcgaacgtatccaacaca
atcaacacttcgtccgtattctttatcatcaaatgctccaactacccatttgacacaatt
aacaccaatgccatctcat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAAATCTGCAGCGTCGACTGTTATT 143 363 507 Antisense
GGAACTCCAAACTATTTAAGCCCTG 91 529 532 Antisense
AAGAGACCGGACGTATCACAGCTGC 639 153 772 Antisense
CACTTGTTCTTCCCTATTTGATATC 209 197 806 Antisense
ATCGAACCTCCACCGACGGATAAGA 223 37 853 Antisense
AAGCCATCAGCTTCATTGAGCAGTC 84 149 880 Antisense
AGTCGACTTCGAACGTATCCAACAC 489 59 901 Antisense
GTATCCAACACAATCAACACTTCGT 199 455 915 Antisense
CTTCGTCCGTATTCTTTATCATCAA 164 221 934 Antisense
TATCATCAAATGCTCCAACTACCCA 414 659 950 Antisense
ACAATTAACACCAATGCCATCTCAT 273 115 981 Antisense
Sequence Source Affymetrix Proprietary Database