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[190592_at] serine/threonine kinase

Description C04G2.2 /REP_DB=WormBase Gene ID /WP=CE05212 /TR=Q17631 /GB=CAA94676.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster 6grp_total > 85      4grp_total > 01      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 105
1 2 3 4 range
A 64
(0)
A 		20.2
(-3)
A 		62.6
(-0)
A 		106.4
(3)
A 		86
B 33.2
(-1.4)
A 		18.2
(-3)
A 		62.8
(1.9)
A 		73
(3)
A 		55
C 39.5
(-2)
A 		81.7
(0.5)
A 		22.9
(-3)
A 		123.6
(3)
A 		101
avr 45.6
(-2.4) 		40
(-3) 		49.4
(-2.1) 		101
(3) 		61

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 142
1 2 3 4 5 6 range
A 30.6
(-3)
A 		91.8
(-0.4)
A 		59.4
(-1.8)
A 		107
(0.2)
A 		117.7
(0.7)
A 		172.8
(3)
P 		142
B 74.2
(-0.3)
A 		53.4
(-2.1)
A 		42.4
(-3)
A 		90
(1.1)
A 		111.9
(3)
A 		109.6
(2.8)
A 		70
C 50.4
(-2.9)
A 		70.3
(-1.8)
A 		48.4
(-3)
A 		156.6
(3)
A 		113.3
(0.6)
A 		154.3
(2.9)
A 		108
avr 51.7
(-2.9) 		71.8
(-1.6) 		50.1
(-3) 		117.9
(1.3) 		114.3
(1) 		145.6
(3) 		96
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 19
1 2 3 4 range
A 23.3
(3)
A 		4.4
(-3)
A 		16.4
(0.8)
A 		15.6
(0.6)
A 		19
B 10.6
(0.3)
A 		4.5
(-3)
A 		14.6
(2.5)
A 		15.6
(3)
A 		11
C 13.1
(-1)
A 		23.5
(3)
A 		8
(-3)
A 		20.8
(2)
A 		16
avr 15.7
(1.5) 		10.8
(-3) 		13
(-1) 		17.3
(3) 		7

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 46
1 2 3 4 5 6 range
A 5.6
(-3)
A 		32.6
(1.4)
A 		12.9
(-1.8)
A 		27.1
(0.5)
A 		35.5
(1.9)
A 		42.1
(3)
P 		37
B 25.8
(-0.4)
A 		17.8
(-1.7)
A 		10.3
(-3)
A 		23.8
(-0.7)
A 		45.5
(3)
A 		40.9
(2.2)
A 		35
C 18.7
(-2)
A 		21.4
(-1.6)
A 		12.3
(-3)
A 		31.5
(-0.1)
A 		36.7
(0.7)
A 		51.7
(3)
A 		39
avr 16.7
(-2.1) 		23.9
(-0.8) 		11.8
(-3) 		27.5
(-0.2) 		39.2
(2) 		44.9
(3) 		33
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190592_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.8498
Sequence Type Exemplar sequence
Representative Public ID C04G2.2 NCBI
Target Description C04G2.2 /REP_DB=WormBase Gene ID /WP=CE05212 /TR=Q17631 /GB=CAA94676.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069431(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069431 NCBI Caenorhabditis elegans C04G2.2 (C04G2.2) mRNA, complete cds. 11/11 None
SNAP00000040131 ENSEMBL cdna:SNAP chromosome:CEL140:IV:10090706:10092307:1 11/11 None
GENEFINDER00000040147 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:10090706:10092307:1 11/11 None
C04G2.2 ENSEMBL cdna:known chromosome:CEL140:IV:10090706:10092307:1 gene:C04G2.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:10090711-10092313(+) 100.0 100.0
Public Domain and Genome References
Gene Title serine/threonine kinase
Ensembl C04G2.2
Entrez Gene 182232 Entrez gene
SwissProt Q17631 EMBL-EBI
WormBase CE05212 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA94676 Hypothetical protein C04G2.2 [Caenorhabditis elegans] ref|NP_501832.1| C04G2.2 [Caenorhabditis elegans] 0.0
blast CAE63920 Hypothetical protein CBG08492 [Caenorhabditis briggsae] 1.0E-161
blast CAE71718 Hypothetical protein CBG18695 [Caenorhabditis briggsae] 1.0E-155
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 1.0E-29
Sequence
Target Sequence 
>C. ELEGANS:190592_AT
aaaacttggagtgctcgtcgtgctcgtggaactgcagaattccgtggaacacttcgttac
acgtccccaaatgtccattttcgtaaagaacaaggtcgagtcgacgatatctggtctcta
ctcttcgtgctcatcgagcttaatggagggcttccatggcagaatgttcagaagagagaa
gaggttgaagcaatgaaaatgataatgacagatcaagatgttatgttgaacatgcctcct
tgtatgtgtgacatcattcctcactttcgtacacttgactgttacatgagaccggattat
cttttggtgttcaaagctctttggcaagtgatgcttaatgaaggacagactacaagctct
cgcttcgattgggaaacttcggatccagatccatcaatctctccggcggattgggaaaat
ccagacggtcgtttcttcaaactggacaaaatcggaatcaatggaccacctcccatggac
aaatgtgc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAAACTTGGAGTGCTCGTCGTGCTC 626 129 577 Antisense
CACGTCCCCAAATGTCCATTTTCGT 691 195 636 Antisense
CGACGATATCTGGTCTCTACTCTTC 481 251 678 Antisense
GGAGGGCTTCCATGGCAGAATGTTC 332 515 721 Antisense
GAACATGCCTCCTTGTATGTGTGAC 416 349 804 Antisense
ATGTGTGACATCATTCCTCACTTTC 704 49 820 Antisense
CTCACTTTCGTACACTTGACTGTTA 647 223 836 Antisense
AAGGACAGACTACAAGCTCTCGCTT 441 159 917 Antisense
CCATCAATCTCTCCGGCGGATTGGG 328 271 967 Antisense
ATCCAGACGGTCGTTTCTTCAAACT 53 33 995 Antisense
GACCACCTCCCATGGACAAATGTGC 544 381 1040 Antisense
Sequence Source Affymetrix Proprietary Database