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[190577_s_at] proton-channel protein

Description K07B1.3 /REP_DB=WormBase Gene ID /WP=CE11880 /TR=O01883 /GB=AAB54239.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=proton-channel protein
Cluster 6grp_high1_10_10 > 67      4grp_high_8_8 > 26      6grp_total > 68      4grp_total > 29      6grp_cgc > 39      6grp_high1_sub > Da      6grp_cgc_sub > Cu      6grp_total_sub > Increase      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 131
1 2 3 4 range
A 266.6
(1.2)
P 		248.5
(0.3)
P 		175.5
(-3)
M 		306.8
(3)
M 		131
B 225.2
(3)
P 		196.4
(-0.8)
P 		179.9
(-3)
P 		189.8
(-1.7)
P 		45
C 265.8
(3)
P 		225.9
(-0.9)
P 		203.8
(-3)
P 		261.3
(2.6)
P 		62
avr 252.5
(3) 		223.6
(0.4) 		186.4
(-3) 		252.6
(3) 		66

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 173
1 2 3 4 5 6 range
A 257.5
(1.1)
A 		138.7
(-3)
P 		213
(-0.4)
P 		160
(-2.3)
P 		211.4
(-0.5)
P 		311.2
(3)
P 		173
B 204.4
(-1.3)
P 		206
(-1.2)
P 		176.7
(-3)
P 		205.9
(-1.3)
P 		222.2
(-0.3)
P 		277
(3)
P 		100
C 210.3
(-0.4)
P 		223.1
(0.2)
P 		148.8
(-3)
P 		183.3
(-1.5)
P 		182
(-1.6)
P 		288.6
(3)
P 		140
avr 224.1
(-0.6) 		189.3
(-2.5) 		179.5
(-3) 		183.1
(-2.8) 		205.2
(-1.6) 		292.3
(3) 		113
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 57
1 2 3 4 range
A 97.1
(3)
P 		53.9
(-2)
P 		45.9
(-2.9)
M 		44.9
(-3)
M 		52
B 71.8
(3)
P 		48.5
(-1.5)
P 		41.7
(-2.8)
P 		40.5
(-3)
P 		31
C 88
(3)
P 		64.9
(-0.2)
P 		71
(0.7)
P 		44.1
(-3)
P 		44
avr 85.6
(3) 		55.8
(-1.2) 		52.9
(-1.6) 		43.2
(-3) 		42

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 66
1 2 3 4 5 6 range
A 47.5
(-1.8)
A 		49.3
(-1.5)
P 		46.4
(-2)
P 		40.6
(-3)
P 		63.8
(1)
P 		75.8
(3)
P 		35
B 71.1
(-0.2)
P 		68.6
(-0.4)
P 		42.9
(-3)
P 		54.5
(-1.8)
P 		90.3
(1.7)
P 		103.3
(3)
P 		60
C 77.9
(1.1)
P 		68.1
(0.1)
P 		37.9
(-2.9)
P 		36.9
(-3)
P 		58.9
(-0.8)
P 		96.6
(3)
P 		60
avr 65.5
(-0.2) 		62
(-0.6) 		42.4
(-3) 		44
(-2.8) 		71
(0.5) 		91.9
(3) 		50
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 190577_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.12476
Sequence Type Exemplar sequence
Representative Public ID K07B1.3 NCBI
Target Description K07B1.3 /REP_DB=WormBase Gene ID /WP=CE11880 /TR=O01883 /GB=AAB54239.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=proton-channel protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073013(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073013 NCBI Caenorhabditis elegans UnCoupling Protein (mitochondrial substrate carrier) family member (ucp-4) (ucp-4) mRNA, complete cds. 11/11 None
SNAP00000012085 ENSEMBL cdna:SNAP chromosome:CEL140:V:9337357:9338948:1 11/11 None
GENEFINDER00000012098 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:9337357:9338948:1 11/11 None
K07B1.3 ENSEMBL cdna:known chromosome:CEL140:V:9337357:9339182:1 gene:K07B1.3 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:9337356-9338948(+) 100.0 100.0
Public Domain and Genome References
Gene Title proton-channel protein
Gene Symbol ucp-4
Ensembl K07B1.3
Entrez Gene 179315 Entrez gene
SwissProt O01883 EMBL-EBI
WormBase CE28591 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:262610_AT mitochondrial substrate carrier family protein at
CANINE_2:CFA.2665.1.A1_AT similar to Mitochondrial uncoupling protein 4 (UCP 4) (Solute carrier family 25, member 27) cfa
CANINE_2:CFAAFFX.3972.1.S1_AT similar to Mitochondrial uncoupling protein 4 (UCP 4) (Solute carrier family 25, member 27) cfa
DROSOPHILA_2:1622912_AT dm
DROSGENOME1:145263_AT dm
HU35KSUBD:RC_N57792_AT solute carrier family 25, member 27 hs
U133_X3P:HS2.40510.2.S1_3P_AT solute carrier family 25, member 27 hs
U133_X3P:HS2.40510.1.S1_3P_S_AT solute carrier family 25, member 27 hs
U133_X3P:HS.40510.1.S2_3P_AT solute carrier family 25, member 27 hs
U133_X3P:HS.145008.0.A1_3P_AT solute carrier family 25, member 27 hs
HG-U133_PLUS_2:1552774_A_AT solute carrier family 25, member 27 hs
HG-U133_PLUS_2:1554161_AT solute carrier family 25, member 27 hs
HG-U133_PLUS_2:230624_AT solute carrier family 25, member 27 hs
HG-U133B:230624_AT solute carrier family 25, member 27 hs
HG-U133_PLUS_2:231787_AT solute carrier family 25, member 27 hs
HG-U133B:231787_AT solute carrier family 25, member 27 hs
HG-U95E:73839_AT solute carrier family 25, member 27 hs
HG-U95E:77110_AT solute carrier family 25, member 27 hs
HG-U133_PLUS_2:229361_AT Solute carrier family 25, member 27 hs
HG-U133B:229361_AT Solute carrier family 25, member 27 hs
HU35KSUBC:RC_N89967_AT Solute carrier family 25, member 27 hs
U133_X3P:HS.40510.0.A1_3P_AT Solute carrier family 25, member 27 hs
MOE430B:1431201_AT solute carrier family 25, member 27 mm
MOUSE430_2:1431201_AT solute carrier family 25, member 27 mm
MOE430B:1454230_A_AT solute carrier family 25, member 27 mm
MOUSE430_2:1454230_A_AT solute carrier family 25, member 27 mm
MOE430B:1458119_AT solute carrier family 25, member 27 mm
MOUSE430_2:1458119_AT solute carrier family 25, member 27 mm
MG-U74BV2:114859_AT Solute carrier family 25, member 27 (Slc25a27), mRNA mm
MOE430B:1440090_AT Solute carrier family 25, member 27 (Slc25a27), mRNA mm
MOUSE430_2:1440090_AT Solute carrier family 25, member 27 (Slc25a27), mRNA mm
RAE230A:1371141_AT solute carrier family 25, member 27 rn
RAT230_2:1371141_AT solute carrier family 25, member 27 rn
RAE230A:1387433_A_AT solute carrier family 25, member 27 rn
RAT230_2:1387433_A_AT solute carrier family 25, member 27 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6810 transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5743 mitochondrial inner membrane inferred from electronic annotation QuickGO AmiGO
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5215 transporter activity inferred from electronic annotation QuickGO AmiGO
5488 binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB54239 Uncoupling protein (mitochondrial substrate carrier) protein 4 [Caenorhabditis elegans] ref|NP_505414.1| UnCoupling Protein (mitochondrial substrate carrier) family member (ucp-4) [Caenorhabditis elegans] 1.0E-174
blast AAB54239 Uncoupling protein (mitochondrial substrate carrier) protein 4 [Caenorhabditis elegans] ref|NP_505414.1| UnCoupling Protein (mitochondrial substrate carrier) family member (ucp-4) [Caenorhabditis elegans] 1.0E-173
blast CAE72155 Hypothetical protein CBG19253 [Caenorhabditis briggsae] 1.0E-166
blast CAE72155 Hypothetical protein CBG19253 [Caenorhabditis briggsae] 1.0E-164
blast XP_852329 PREDICTED: similar to Mitochondrial uncoupling protein 4 (UCP 4) (Solute carrier family 25, member 27) [Canis familiaris] 2.0E-77
Protein Domains
Database ID Description E-Value
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 2.8E-21
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 4.1E-33
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 8.9E-32
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 1.1E-20
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 4.1E-33
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 8.9E-32
Sequence
Target Sequence 
>C. ELEGANS:190577_S_AT
gctttgtggtgcattttctgggcttattgctcaattcgcggctagtccgaccgatttggt
gaaggttcaaatgcaaatggaaggacttcgaagattgcagaaacaacctttacgatatac
aggagcaaccgattgcttcagatccctttatcgaacacaaggattttttggattgtggat
tggttggatgccaaattgtcagcgagcagcactgctcaatatggctgatattgctacata
tgacagtgtgaagcatgggctcattgataatttcgaacttaaagataattggctaactca
tgccgttgctagtgcttgtgctggacttgctgctgccattgtatcacttccatcagatgt
cgttaaaactcgaatgatggatcagattcggcacgagctggacgccaaaatgatgcataa
gaaaaatacgcatgtggatctatacaaaggcgtcgtcgattgctacataaaaattatcaa
aaacgaaggatttttctcactttacaaaggattccttccatcttatattcgaatggctcc
gtggtctcttaccttctgggtctcctacgaaga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GCTTTGTGGTGCATTTTCTGGGCTT 324 303 438 Antisense
GCTTATTGCTCAATTCGCGGCTAGT 241 305 459 Antisense
GGCTAGTCCGACCGATTTGGTGAAG 173 535 477 Antisense
ATTGCTTCAGATCCCTTTATCGAAC 702 5 569 Antisense
TCATGCCGTTGCTAGTGCTTGTGCT 122 623 735 Antisense
TGGACTTGCTGCTGCCATTGTATCA 22 549 759 Antisense
GGATCAGATTCGGCACGAGCTGGAC 74 511 816 Antisense
AGGCGTCGTCGATTGCTACATAAAA 65 55 885 Antisense
GGATTCCTTCCATCTTATATTCGAA 200 509 946 Antisense
TATATTCGAATGGCTCCGTGGTCTC 104 659 961 Antisense
TTACCTTCTGGGTCTCCTACGAAGA 256 683 986 Antisense
Sequence Source Affymetrix Proprietary Database