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[190571_at] serine/threonine kinase

Description D2045.7 /REP_DB=WormBase Gene ID /WP=CE03103 /TR=Q18988 /GB=CAA84698.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster 6grp_total > 75      4grp_total > 14      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 84
1 2 3 4 range
A 89.9
(0.6)
M 		40
(-3)
A 		71.9
(-0.7)
A 		123.6
(3)
A 		84
B 87.9
(1.8)
P 		80.6
(0.3)
A 		65.2
(-3)
A 		93.5
(3)
P 		28
C 96.8
(3)
P 		67.6
(-2.9)
A 		67.1
(-3)
A 		90.8
(1.8)
A 		30
avr 91.5
(1.3) 		62.7
(-3) 		68.1
(-2.2) 		102.6
(3) 		40

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 119
1 2 3 4 5 6 range
A 17.5
(-3)
A 		76.6
(-0)
A 		100.6
(1.2)
A 		136.5
(3)
P 		81.7
(0.2)
A 		98.4
(1.1)
P 		119
B 80.3
(-1.9)
M 		68.6
(-3)
A 		106.8
(0.7)
A 		72.7
(-2.6)
A 		106.7
(0.7)
P 		130
(3)
A 		61
C 84.2
(-0.9)
M 		81.4
(-1.2)
A 		63.4
(-3)
A 		110.6
(1.8)
P 		66.8
(-2.7)
A 		122.4
(3)
P 		59
avr 60.7
(-3) 		75.5
(-1.4) 		90.3
(0.2) 		106.6
(1.9) 		85.1
(-0.4) 		116.9
(3) 		56
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 24
1 2 3 4 range
A 32.7
(3)
M 		8.7
(-3)
A 		18.8
(-0.5)
A 		18.1
(-0.7)
A 		24
B 28
(3)
P 		19.9
(-0.8)
A 		15.1
(-3)
A 		19.9
(-0.8)
P 		13
C 32
(3)
P 		19.4
(-1.5)
A 		23.4
(-0.1)
A 		15.3
(-3)
A 		17
avr 30.9
(3) 		16
(-3) 		19.1
(-1.8) 		17.8
(-2.3) 		15

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 45
1 2 3 4 5 6 range
A 3.2
(-3)
A 		27.2
(1.6)
A 		21.9
(0.6)
A 		34.6
(3)
P 		24.7
(1.1)
A 		24
(1)
P 		31
B 27.9
(-1.2)
M 		22.8
(-2.3)
A 		25.9
(-1.6)
A 		19.3
(-3)
A 		43.3
(1.9)
P 		48.5
(3)
A 		29
C 31.2
(0.6)
M 		24.8
(-0.9)
A 		16.1
(-3)
A 		22.2
(-1.5)
P 		21.6
(-1.7)
A 		41
(3)
P 		25
avr 20.8
(-3) 		24.9
(-1.6) 		21.3
(-2.8) 		25.4
(-1.4) 		29.9
(0.2) 		37.8
(3) 		17
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190571_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.6493
Sequence Type Exemplar sequence
Representative Public ID D2045.7 NCBI
Target Description D2045.7 /REP_DB=WormBase Gene ID /WP=CE03103 /TR=Q18988 /GB=CAA84698.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_066910(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_066910 NCBI Caenorhabditis elegans D2045.7 (D2045.7) mRNA, complete cds. 11/11 None
GENEFINDER00000022546 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:10475869:10482025:1 11/11 None
SNAP00000022544 ENSEMBL cdna:SNAP chromosome:CEL140:III:10479786:10482025:1 11/11 None
D2045.7 ENSEMBL cdna:known chromosome:CEL140:III:10479765:10482025:1 gene:D2045.7 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:10479921-10482021(+) 100.0 100.0
Public Domain and Genome References
Gene Title serine/threonine kinase
Ensembl D2045.7
Entrez Gene 183953 Entrez gene
SwissProt Q18988 EMBL-EBI
WormBase CE37761 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA84699 Hypothetical protein D2045.9 [Caenorhabditis elegans] ref|NP_001021233.1| D2045.9 [Caenorhabditis elegans] 0.0
blast CAE71465 Hypothetical protein CBG18383 [Caenorhabditis briggsae] 0.0
blast CAA84698 Hypothetical protein D2045.7 [Caenorhabditis elegans] ref|NP_499311.2| D2045.7 [Caenorhabditis elegans] 1.0E-179
blast CAA84698 Hypothetical protein D2045.7 [Caenorhabditis elegans] ref|NP_499311.2| D2045.7 [Caenorhabditis elegans] 1.0E-178
blast CAA84698 Hypothetical protein D2045.7 [Caenorhabditis elegans] ref|NP_499311.2| D2045.7 [Caenorhabditis elegans] 1.0E-165
blast CAE71467 Hypothetical protein CBG18385 [Caenorhabditis briggsae] 1.0E-138
blast CAE71467 Hypothetical protein CBG18385 [Caenorhabditis briggsae] 1.0E-130
blast XP_758315 hypothetical protein UM02168.1 [Ustilago maydis 521] gb|EAK83290.1| hypothetical protein UM02168.1 [Ustilago maydis 521] 5.0E-22
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 4.6E-23
Pfam IPR000719 EMBL-EBI Protein kinase 4.6E-23
Pfam IPR002654 EMBL-EBI Glycosyl transferase, family 25 1.3E-36
Pfam IPR000719 EMBL-EBI Protein kinase 6.1E-23
Sequence
Target Sequence 
>C. ELEGANS:190571_AT
tccggaattgtgtcagctatcgagcaactgcatggctttgaatttgctcatttggacatt
aagcccgccaatattctgaaatccggcgacactataaagatgattgatttcggatcagct
acaaaaatgccgatcgaaatcaaaacttctgcagatcatcacaggcataaggaggatgcc
gaggagttgtgtagtatgatgtatagggctccggagctttttaactgtgaaattggctca
actctgacgactgctgtcgatgtttgggctctcggcgtgtgcctctacgagttcctgtac
ctggagaacccgttcaacaagatttacgaacaaggtggcagtattgcactggcgacacaa
agtccgcatatgatcaagtggaatgagaaccgacacatcagcgaaaaatcgataaatctc
atcaaatccatcctaatcgtcgatcccaaccagcgaccaacaattggagaacttcgagcg
aaagttgacaatcttctggcgaacttcgaca

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TCCGGAATTGTGTCAGCTATCGAGC 14 593 283 Antisense
GCTCATTTGGACATTAAGCCCGCCA 253 301 328 Antisense
TAAGCCCGCCAATATTCTGAAATCC 136 639 342 Antisense
AACTTCTGCAGATCATCACAGGCAT 198 139 426 Antisense
GGCTCCGGAGCTTTTTAACTGTGAA 416 539 489 Antisense
AAATTGGCTCAACTCTGACGACTGC 397 115 512 Antisense
ACGACTGCTGTCGATGTTTGGGCTC 413 93 529 Antisense
TTCCTGTACCTGGAGAACCCGTTCA 274 695 574 Antisense
GGTGGCAGTATTGCACTGGCGACAC 161 499 616 Antisense
TCAAATCCATCCTAATCGTCGATCC 431 629 704 Antisense
GACAATCTTCTGGCGAACTTCGACA 160 365 769 Antisense
Sequence Source Affymetrix Proprietary Database