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[190562_at] serine/threonine kinase

Description D2045.5 /REP_DB=WormBase Gene ID /WP=CE00935 /TR=Q18984 /GB=CAA84694.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster 6grp_total > 87      4grp_total > 02      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 74
1 2 3 4 range
A 9.3
(-2.2)
A 		3
(-3)
A 		9.6
(-2.2)
A 		51.2
(3)
A 		48
B 3.6
(-2.9)
A 		16.5
(3)
A 		3.4
(-3)
A 		3.6
(-2.9)
A 		13
C 13.4
(-2.6)
A 		9
(-3)
A 		18.3
(-2.2)
A 		77.1
(3)
A 		68
avr 8.8
(-3) 		9.5
(-2.9) 		10.4
(-2.7) 		44
(3) 		35

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 82
1 2 3 4 5 6 range
A 10.9
(-2.3)
A 		2.4
(-2.9)
A 		1.6
(-3)
A 		30.2
(-0.9)
A 		6.7
(-2.6)
A 		83.3
(3)
P 		82
B 26.6
(-1.2)
A 		6.6
(-2.8)
A 		3.6
(-3)
A 		5.2
(-2.9)
A 		42.3
(0.1)
A 		79.2
(3)
M 		76
C 5.1
(-2.7)
A 		2.2
(-3)
A 		3.8
(-2.8)
A 		29
(-0.1)
A 		28.6
(-0.1)
A 		56.9
(3)
P 		55
avr 14.2
(-2) 		3.7
(-2.9) 		3
(-3) 		21.5
(-1.4) 		25.9
(-1) 		73.1
(3) 		70
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 12
1 2 3 4 range
A 3.4
(-0.6)
A 		0.7
(-3)
A 		2.5
(-1.4)
A 		7.5
(3)
A 		7
B 1.2
(-2.3)
A 		4.1
(3)
A 		0.8
(-3)
A 		0.8
(-3)
A 		3
C 4.4
(-2)
A 		2.6
(-3)
A 		6.4
(-0.8)
A 		13
(3)
A 		10
avr 3
(-2.3) 		2.5
(-3) 		3.2
(-2.1) 		7.1
(3) 		5

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 29
1 2 3 4 5 6 range
A 2
(-2.5)
A 		0.9
(-2.8)
A 		0.4
(-3)
A 		7.7
(-0.8)
A 		2
(-2.5)
A 		20.3
(3)
P 		20
B 9.2
(-1.3)
A 		2.2
(-2.7)
A 		0.9
(-3)
A 		1.4
(-2.9)
A 		17.2
(0.4)
A 		29.5
(3)
M 		29
C 1.9
(-2.6)
A 		0.7
(-3)
A 		1
(-2.9)
A 		5.8
(-1.3)
A 		9.3
(-0.2)
A 		19
(3)
P 		18
avr 4.4
(-2) 		1.3
(-2.9) 		0.8
(-3) 		5
(-1.9) 		9.5
(-0.6) 		22.9
(3) 		22
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190562_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.8082
Sequence Type Exemplar sequence
Representative Public ID D2045.5 NCBI
Target Description D2045.5 /REP_DB=WormBase Gene ID /WP=CE00935 /TR=Q18984 /GB=CAA84694.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_066907(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_066907 NCBI Caenorhabditis elegans D2045.5 (D2045.5) mRNA, complete cds. 11/11 None
SNAP00000022540 ENSEMBL cdna:SNAP chromosome:CEL140:III:10467988:10469384:-1 11/11 None
GENEFINDER00000022547 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:10467988:10468557:-1 11/11 None
D2045.5 ENSEMBL cdna:known chromosome:CEL140:III:10467988:10469384:-1 gene:D2045.5 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000036386 5/11 Cross Hyb Matching Probes None
W05B2.3 6/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:10467983-10469380(-) 100.0 100.0
chrIII:10967651-10969345(-) 95.27 95.27
Public Domain and Genome References
Gene Title serine/threonine kinase
Ensembl D2045.5
Entrez Gene 183952 Entrez gene
SwissProt Q18984 EMBL-EBI
WormBase CE00935 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA84694 Hypothetical protein D2045.5 [Caenorhabditis elegans] ref|NP_499308.1| D2045.5 [Caenorhabditis elegans] 0.0
blast CAA84694 Hypothetical protein D2045.5 [Caenorhabditis elegans] ref|NP_499308.1| D2045.5 [Caenorhabditis elegans] 1.0E-110
blast CAE68976 Hypothetical protein CBG14958 [Caenorhabditis briggsae] 8.0E-59
blast NP_491162 Y47G6A.13 [Caenorhabditis elegans] gb|AAF60673.1| Hypothetical protein Y47G6A.13 [Caenorhabditis elegans] 5.0E-57
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 1.9E-11
Sequence
Target Sequence 
>C. ELEGANS:190562_AT
tccgtcaattcaccgccaaacgagagaacggagagaccgcactccgcagagctcgatccg
gcgagcaactattccgtggaactcctcgctattgcagcatgaacgttcacaatcggaaag
agcagggacgcgtcgatgatctctggtcgtggctctacatgctcatcgagcttcattgtg
ggctcccgtggcgccgactgaccgatgagaaggagattatggacgcgaagattgcatgct
ccatggaaactttgttgaaagggtgtcccaaggaatttgcgaatattcacaagtacctgg
agacactggaatacaagagccgcccggattatttcggcctgtggagcgagtgctttgccg
gtttcaagagagtccgtggatcgttctttggccgattcgagtgggagcttgggaagggcg
gtggtgaggagatgttcacggctctgtcgatcagtgagaagagagctcctaacgattata
aggtggcgacgaagatgcaaatggcgaagaagatctggccgtatgcggattctgct

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TCCGTCAATTCACCGCCAAACGAGA 69 595 503 Antisense
CGATCCGGCGAGCAACTATTCCGTG 532 247 556 Antisense
AACTCCTCGCTATTGCAGCATGAAC 198 141 582 Antisense
AGAGCAGGGACGCGTCGATGATCTC 549 69 621 Antisense
GGCTCTACATGCTCATCGAGCTTCA 620 537 653 Antisense
GACGCGAAGATTGCATGCTCCATGG 529 381 724 Antisense
ACAAGAGCCGCCCGGATTATTTCGG 78 113 815 Antisense
CGGCCTGTGGAGCGAGTGCTTTGCC 358 241 837 Antisense
GAGAGTCCGTGGATCGTTCTTTGGC 564 395 870 Antisense
TGTTCACGGCTCTGTCGATCAGTGA 463 561 935 Antisense
GATCTGGCCGTATGCGGATTCTGCT 369 413 1014 Antisense
Sequence Source Affymetrix Proprietary Database