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[190527_at] matrix metalloprotease

Description H36L18.1 /REP_DB=WormBase Gene ID /WP=CE11610 /TR=O17913 /GB=CAB08559.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=matrix metalloprotease
Cluster 6grp_total > 47      4grp_total > 07      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 27
1 2 3 4 range
A 30.3
(0.2)
A 		15.8
(-3)
A 		25.3
(-0.9)
A 		43.2
(3)
A 		27
B 33.1
(-1.5)
A 		31.1
(-3)
P 		39.3
(3)
P 		31.3
(-2.9)
P 		8
C 40.9
(3)
A 		35.4
(1.1)
A 		33.2
(0.4)
A 		23.1
(-3)
A 		18
avr 34.8
(3) 		27.4
(-3) 		32.6
(1.2) 		32.5
(1.1) 		7

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 63
1 2 3 4 5 6 range
A 42.5
(2.6)
A 		23.8
(-0.3)
A 		28.4
(0.4)
A 		7
(-3)
A 		19.8
(-1)
A 		44.9
(3)
A 		38
B 49.5
(3)
A 		30.3
(-0.6)
A 		17.4
(-3)
A 		24.7
(-1.6)
A 		20.2
(-2.5)
A 		34.2
(0.1)
P 		32
C 27
(-2)
A 		42.4
(-0.2)
A 		32.6
(-1.3)
A 		69.6
(3)
A 		18.5
(-3)
A 		28.8
(-1.8)
A 		51
avr 39.7
(3) 		32.2
(0.8) 		26.1
(-1) 		33.8
(1.2) 		19.5
(-3) 		36
(1.9) 		20
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 10
1 2 3 4 range
A 11
(3)
A 		3.4
(-3)
A 		6.6
(-0.5)
A 		6.3
(-0.7)
A 		8
B 10.6
(3)
A 		7.7
(-1.5)
P 		9.1
(0.7)
P 		6.7
(-3)
P 		4
C 13.5
(3)
A 		10.2
(0.9)
A 		11.6
(1.8)
A 		3.9
(-3)
A 		10
avr 11.7
(3) 		7.1
(-1.5) 		9.1
(0.4) 		5.6
(-3) 		6

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 15
1 2 3 4 5 6 range
A 7.8
(1)
A 		8.5
(1.4)
A 		6.2
(-0.1)
A 		1.8
(-3)
A 		6
(-0.2)
A 		10.9
(3)
A 		9
B 17.2
(3)
A 		10.1
(-0.3)
A 		4.2
(-3)
A 		6.5
(-1.9)
A 		8.2
(-1.2)
A 		12.7
(0.9)
P 		13
C 10
(0)
A 		13
(2.3)
A 		8.3
(-1.3)
A 		14
(3)
A 		6
(-3)
A 		9.6
(-0.3)
A 		8
avr 11.7
(3) 		10.5
(1.7) 		6.2
(-3) 		7.4
(-1.7) 		6.7
(-2.5) 		11.1
(2.3) 		6
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190527_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.17310
Sequence Type Exemplar sequence
Representative Public ID H36L18.1 NCBI
Target Description H36L18.1 /REP_DB=WormBase Gene ID /WP=CE11610 /TR=O17913 /GB=CAB08559.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=matrix metalloprotease
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_077711(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_077711 NCBI Caenorhabditis elegans H36L18.1 (H36L18.1) mRNA, complete cds. 11/11 None
H36L18.1 ENSEMBL cdna:known chromosome:CEL140:X:12648861:12651406:1 gene:H36L18.1 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
GENEFINDER00000006637 7/11 Cross Hyb Matching Probes None
SNAP00000006636 7/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:12648860-12651406(+) 91.7 100.0
Public Domain and Genome References
Gene Title matrix metalloprotease
Ensembl H36L18.1
Entrez Gene 186805 Entrez gene
SwissProt O17913 EMBL-EBI
WormBase CE28576 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5578 extracellular matrix (sensu Metazoa) inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4222 metalloendopeptidase activity inferred from electronic annotation QuickGO AmiGO
8237 metallopeptidase activity inferred from electronic annotation QuickGO AmiGO
8270 zinc ion binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB08559 Hypothetical protein H36L18.1 [Caenorhabditis elegans] ref|NP_510112.1| H36L18.1 [Caenorhabditis elegans] 0.0
blast CAE57229 Hypothetical protein CBG00098 [Caenorhabditis briggsae] 1.0E-70
blast EAA04040 ENSANGP00000021627 [Anopheles gambiae str. PEST] ref|XP_308849.2| ENSANGP00000021627 [Anopheles gambiae str. PEST] 5.0E-40
Protein Domains
Database ID Description E-Value
Pfam IPR001818 EMBL-EBI Peptidase M10A and M12B, matrixin and adamalysin 7.9E-22
Pfam IPR000585 EMBL-EBI Hemopexin repeat 3.9E-7
Pfam IPR000585 EMBL-EBI Hemopexin repeat 6.1E-10
Sequence
Target Sequence 
>C. ELEGANS:190527_AT
gatttcacagggactcacagacactcctgatggaatcaatgcagctttatattaccatga
agatggaaaaccatattttttcaaaagtatgcagagagaaagttatcgtatcgaattatt
cacaattttagaatcttatttctggcaatattctcgttacggaaaacacaagttatggcc
gcgtgcaattgtgtcgatttttgaaaatcaggtacctatagtttcatggttaagagtttc
aataactgtttattgcaaacgtcattttttttccaggtcatcaaaatttactgttggttt
cagtttcaaatctgaaaaaaacattttttttatttcccaagtgaaaaattacaaattttc
tgttcataaaatttacatatcttttcagaattcacctcctgaaattgatgctgcattcca
gttgaataatacttcgtcttttctgtttcat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GATTTCACAGGGACTCACAGACACT 34 427 963 Antisense
GGACTCACAGACACTCCTGATGGAA 492 525 973 Antisense
GAATCAATGCAGCTTTATATTACCA 574 327 995 Antisense
GAATCTTATTTCTGGCAATATTCTC 195 329 1093 Antisense
GAAAACACAAGTTATGGCCGCGTGC 607 353 1124 Antisense
TATGGCCGCGTGCAATTGTGTCGAT 439 653 1136 Antisense
ATCAGGTACCTATAGTTTCATGGTT 612 29 1169 Antisense
CGTCATTTTTTTTCCAGGTCATCAA 228 247 1222 Antisense
ATATCTTTTCAGAATTCACCTCCTG 176 21 1339 Antisense
GATGCTGCATTCCAGTTGAATAATA 104 415 1369 Antisense
TAATACTTCGTCTTTTCTGTTTCAT 115 635 1389 Antisense
Sequence Source Affymetrix Proprietary Database