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[190521_at] serine/threonine kinase

Description ZC373.3 /REP_DB=WormBase Gene ID /WP=CE02376 /TR=Q23259 /GB=CAA88975.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster 6grp_total > 99      4grp_total > 34      6grp_total_sub > Increase      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 44
1 2 3 4 range
A 11.3
(-3)
A 		29.3
(0.7)
A 		36
(2.1)
A 		40.5
(3)
A 		29
B 27.8
(-1.9)
A 		55.4
(3)
A 		21.5
(-3)
A 		33.4
(-0.9)
A 		34
C 12.9
(-3)
A 		50.8
(3)
A 		40.2
(1.3)
A 		29.1
(-0.4)
A 		38
avr 17.3
(-3) 		45.2
(3) 		32.6
(0.3) 		34.3
(0.7) 		28

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 40
1 2 3 4 5 6 range
A 40.6
(3)
A 		9.2
(-1.8)
A 		1.6
(-3)
A 		14
(-1.1)
A 		29
(1.2)
A 		37
(2.4)
A 		39
B 4.7
(-2.7)
A 		20.9
(0.8)
A 		3.1
(-3)
A 		24.4
(1.5)
A 		31.2
(3)
A 		3.2
(-3)
A 		28
C 4.7
(-3)
A 		6
(-2.8)
A 		41.6
(3)
A 		10.6
(-2)
A 		6.7
(-2.7)
A 		22.7
(-0.1)
A 		37
avr 16.7
(-0.3) 		12
(-3) 		15.4
(-1) 		16.3
(-0.5) 		22.3
(3) 		21
(2.2) 		10
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 11
1 2 3 4 range
A 4.1
(-3)
A 		6.4
(-0.4)
A 		9.4
(3)
A 		5.9
(-1)
A 		5
B 8.8
(-0.4)
A 		13.7
(3)
A 		5
(-3)
A 		7.1
(-1.6)
A 		9
C 4.3
(-3)
A 		14.6
(3)
A 		14
(2.7)
A 		4.9
(-2.7)
A 		10
avr 5.7
(-3) 		11.6
(3) 		9.5
(0.9) 		6
(-2.7) 		6

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 12
1 2 3 4 5 6 range
A 7.5
(2)
A 		3.3
(-1)
A 		0.4
(-3)
A 		3.5
(-0.8)
A 		8.8
(2.9)
A 		9
(3)
A 		9
B 1.6
(-2.6)
A 		7
(0.1)
A 		0.8
(-3)
A 		6.5
(-0.1)
A 		12.7
(3)
A 		1.2
(-2.8)
A 		12
C 1.8
(-3)
A 		1.8
(-3)
A 		10.6
(3)
A 		2.1
(-2.8)
A 		2.2
(-2.7)
A 		7.6
(1)
A 		9
avr 3.6
(-3) 		4
(-2.4) 		3.9
(-2.6) 		4
(-2.4) 		7.9
(3) 		5.9
(0.2) 		4
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190521_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.16993
Sequence Type Exemplar sequence
Representative Public ID ZC373.3 NCBI
Target Description ZC373.3 /REP_DB=WormBase Gene ID /WP=CE02376 /TR=Q23259 /GB=CAA88975.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_077287(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_077287 NCBI Caenorhabditis elegans ZC373.3 (ZC373.3) mRNA, complete cds. 11/11 None
SNAP00000017663 ENSEMBL cdna:SNAP chromosome:CEL140:X:10059671:10061611:1 11/11 None
GENEFINDER00000017675 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:10059937:10062379:1 11/11 None
ZC373.3 ENSEMBL cdna:known chromosome:CEL140:X:10060502:10061611:1 gene:ZC373.3 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:10060501-10061611(+) 100.0 100.0
Public Domain and Genome References
Gene Title serine/threonine kinase
Ensembl ZC373.3
Entrez Gene 191145 Entrez gene
SwissProt Q23259 EMBL-EBI
WormBase CE02376 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA88975 Hypothetical protein ZC373.3 [Caenorhabditis elegans] ref|NP_509688.1| ZC373.3 [Caenorhabditis elegans] 0.0
blast CAA88975 Hypothetical protein ZC373.3 [Caenorhabditis elegans] ref|NP_509688.1| ZC373.3 [Caenorhabditis elegans] 1.0E-174
blast CAA88975 Hypothetical protein ZC373.3 [Caenorhabditis elegans] ref|NP_509688.1| ZC373.3 [Caenorhabditis elegans] 1.0E-169
blast AAB09099 Hypothetical protein F22H10.1 [Caenorhabditis elegans] ref|NP_510698.2| F22H10.1 [Caenorhabditis elegans] 4.0E-62
blast AAB09099 Hypothetical protein F22H10.1 [Caenorhabditis elegans] ref|NP_510698.2| F22H10.1 [Caenorhabditis elegans] 7.0E-61
blast CAA91542 Hypothetical protein T01H10.4 [Caenorhabditis elegans] ref|NP_510026.1| T01H10.4 [Caenorhabditis elegans] 4.0E-51
blast CAA91542 Hypothetical protein T01H10.4 [Caenorhabditis elegans] ref|NP_510026.1| T01H10.4 [Caenorhabditis elegans] 6.0E-51
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 1.2E-22
Pfam IPR000719 EMBL-EBI Protein kinase 1.2E-22
Pfam IPR000719 EMBL-EBI Protein kinase 1.2E-22
Sequence
Target Sequence 
>C. ELEGANS:190521_AT
ggctaaacgttcaccaggatcattttcattgaataatttgatcagaatcgcgtaccaaat
cggatccactctgtgctttattcatgacaaatcatttattcatcgcgatctcaaagctga
aaacgttcttgtctctctgaagaacaaggtttgtaagatggtgttgatcgattttggaaa
tgcagtcagatttaaggatgtgaacggaaatgagctgcctgagtttaatgatggctttga
ctacacccattgtactcataaaagcattaatgtgctcctaggaatatctcacacgcagaa
tgacgattgggcctcgttggtttatctactgctggagatgcacggtgtgacttggggctc
gagaactggtgaaatgtttatgaataaagtagaattcgaagctaatcctacagaaatcct
tgtcgataagatgctttggattcataaaatgtaccaggatagtgtggaactgaacatggg
aagagagaacaacaaacagattatggataatttggcaaaggctcgcgagaacttcgactg
tgaat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGCTAAACGTTCACCAGGATCATTT 604 505 387 Antisense
GAATCGCGTACCAAATCGGATCCAC 431 329 431 Antisense
TCGGATCCACTCTGTGCTTTATTCA 565 605 446 Antisense
TGAAAACGTTCTTGTCTCTCTGAAG 515 573 504 Antisense
GAACGGAAATGAGCTGCCTGAGTTT 551 347 588 Antisense
GATGGCTTTGACTACACCCATTGTA 684 405 616 Antisense
GCTCCTAGGAATATCTCACACGCAG 595 297 660 Antisense
GACGATTGGGCCTCGTTGGTTTATC 429 1 688 Antisense
GGAGATGCACGGTGTGACTTGGGGC 145 519 720 Antisense
GACTTGGGGCTCGAGAACTGGTGAA 506 369 735 Antisense
GCTCGCGAGAACTTCGACTGTGAAT 396 299 907 Antisense
Sequence Source Affymetrix Proprietary Database