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[190517_at] tyrosine-protein kinase

Description ZK593.9 /REP_DB=WormBase Gene ID /WP=CE06630 /TR=Q23538 /GB=CAA93423.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=tyrosine-protein kinase
Cluster 6grp_total > 37      4grp_total > 06      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 142
1 2 3 4 range
A 171
(2.7)
P 		102.7
(-3)
A 		172.4
(2.9)
A 		174.1
(3)
A 		71
B 161
(3)
P 		134
(0.9)
A 		125.4
(0.2)
A 		85.6
(-3)
A 		75
C 104.7
(-1.9)
P 		92.7
(-2.4)
A 		78.3
(-3)
A 		220.3
(3)
A 		142
avr 145.6
(1.3) 		109.8
(-3) 		125.4
(-1.1) 		160
(3) 		50

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 102
1 2 3 4 5 6 range
A 145.1
(3)
A 		43.4
(-3)
A 		87.5
(-0.4)
A 		66
(-1.7)
M 		86.6
(-0.5)
A 		105.6
(0.7)
P 		102
B 101.2
(0.8)
A 		125.1
(3)
A 		72.9
(-1.8)
A 		102.1
(0.9)
A 		59.5
(-3)
A 		102.8
(1)
A 		66
C 67.4
(-1.9)
A 		105.9
(2)
P 		56.3
(-3)
A 		115.4
(3)
A 		92.3
(0.7)
A 		76.9
(-0.9)
A 		59
avr 104.6
(3) 		91.5
(0.6) 		72.2
(-3) 		94.5
(1.1) 		79.5
(-1.6) 		95.1
(1.2) 		32
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 44
1 2 3 4 range
A 62.2
(3)
P 		22.3
(-3)
A 		45.1
(0.4)
A 		25.5
(-2.5)
A 		40
B 51.4
(3)
P 		33.1
(-0.3)
A 		29.1
(-1)
A 		18.3
(-3)
A 		33
C 34.7
(1.6)
P 		26.7
(-3)
A 		27.3
(-2.7)
A 		37.1
(3)
A 		10
avr 49.4
(3) 		27.4
(-2.9) 		33.8
(-1.2) 		27
(-3) 		22

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 27
1 2 3 4 5 6 range
A 26.8
(3)
A 		15.4
(-3)
A 		19.1
(-1.1)
A 		16.8
(-2.3)
M 		26.1
(2.6)
A 		25.7
(2.4)
P 		11
B 35.2
(1.4)
A 		41.7
(3)
A 		17.7
(-3)
A 		27
(-0.7)
A 		24.2
(-1.4)
A 		38.3
(2.2)
A 		24
C 25
(0.6)
A 		32.3
(3)
P 		14.3
(-3)
A 		23.2
(-0)
A 		29.9
(2.2)
A 		25.7
(0.8)
A 		18
avr 29
(2.6) 		29.8
(3) 		17
(-3) 		22.3
(-0.5) 		26.7
(1.5) 		29.9
(3) 		13
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190517_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.8555
Sequence Type Exemplar sequence
Representative Public ID ZK593.9 NCBI
Target Description ZK593.9 /REP_DB=WormBase Gene ID /WP=CE06630 /TR=Q23538 /GB=CAA93423.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=tyrosine-protein kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069636(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069636 NCBI Caenorhabditis elegans ZK593.9 (ZK593.9) mRNA, complete cds. 11/11 A 
SNAP00000042099 ENSEMBL cdna:SNAP chromosome:CEL140:IV:10940929:10942837:1 11/11 None
GENEFINDER00000042103 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:10940929:10942837:1 11/11 None
ZK593.9 ENSEMBL cdna:known chromosome:CEL140:IV:10940929:10942837:1 gene:ZK593.9 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:10940934-10942843(+) 100.0 100.0
chrIV:10755550-10757650(-) 90.75 90.75
Public Domain and Genome References
Gene Title tyrosine-protein kinase
Ensembl ZK593.9
Entrez Gene 191356 Entrez gene
SwissProt Q23538 EMBL-EBI
WormBase CE06630 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
7242 intracellular signaling cascade inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA93423 Hypothetical protein ZK593.9 [Caenorhabditis elegans] ref|NP_502037.1| ZK593.9 [Caenorhabditis elegans] 0.0
blast CAA94372 Hypothetical protein T25B9.4 [Caenorhabditis elegans] ref|NP_501994.1| T25B9.4 [Caenorhabditis elegans] 0.0
blast CAE65127 Hypothetical protein CBG09992 [Caenorhabditis briggsae] 1.0E-178
Protein Families
Method ID Description E-Value
hanks 1.9.5 AGC group; AGC Other; DdK2 2.0E-62
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 3.4E-57
Sequence
Target Sequence 
>C. ELEGANS:190517_AT
gatccagaactgaatcgttccaatggaaatatgccaatcccagtagattcatcgacaaag
aagatgcgcaacgacaccgtgtgtatcccaccaccagaagtatctgccgttgttcctcca
gacggatgggctccaatcccggttccagctcccacgaagaaaccgaaagtgtcaaagaaa
gagaaagagagaaagaagaagacttcgaaggactcctcgatgacaacaactacaacgaac
acaaatgagagcgagccgcctgctgatggtcaagtaatttcatcggaatccatgtcctct
gcaaacaaaatggtatccgatgcaaagggaggaagtcctgaaatgttgactccgccactt
gaagagttgaagccatctccgaaag

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GATCCAGAACTGAATCGTTCCAATG 272 415 1174 Antisense
AAGAAGATGCGCAACGACACCGTGT 221 153 1231 Antisense
TGCGCAACGACACCGTGTGTATCCC 188 583 1238 Antisense
ATCCCACCACCAGAAGTATCTGCCG 478 37 1258 Antisense
ACCAGAAGTATCTGCCGTTGTTCCT 261 85 1266 Antisense
CCGTTGTTCCTCCAGACGGATGGGC 622 263 1280 Antisense
TTCCAGCTCCCACGAAGAAACCGAA 36 699 1316 Antisense
TTCATCGGAATCCATGTCCTCTGCA 403 689 1452 Antisense
GAATCCATGTCCTCTGCAAACAAAA 100 331 1459 Antisense
AGTCCTGAAATGTTGACTCCGCCAC 151 61 1507 Antisense
GAAGAGTTGAAGCCATCTCCGAAAG 44 339 1534 Antisense
Sequence Source Affymetrix Proprietary Database