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[190512_s_at] Ank repeat (6 domains)

Description F22G12.4 /REP_DB=WormBase Gene ID /WP=CE15891 /TR=O45398 /GB=CAB07368.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=Ank repeat (6 domains)
Cluster 6grp_total > 59      4grp_total > 59      6grp_total_sub > Cup      4grp_rule_based > L2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 103
1 2 3 4 range
A 77.6
(1.7)
A 		83.7
(3)
A 		73.2
(0.7)
A 		56
(-3)
A 		28
B 70.8
(0.4)
A 		110.3
(3)
A 		99
(2.2)
A 		20.1
(-3)
A 		90
C 76.7
(1.5)
A 		92
(2.5)
A 		98.9
(3)
A 		7.7
(-3)
A 		91
avr 75
(1.2) 		95.3
(3) 		90.4
(2.6) 		27.9
(-3) 		67

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 165
1 2 3 4 5 6 range
A 80.5
(-1.8)
A 		92.5
(-1.3)
A 		54.9
(-3)
A 		134.9
(0.7)
A 		76.8
(-2)
A 		184.8
(3)
A 		130
B 94
(1.6)
A 		87.5
(1)
A 		65
(-1)
A 		101.8
(2.3)
A 		42.9
(-3)
A 		109.8
(3)
M 		67
C 133
(2.5)
A 		70.2
(-0.6)
A 		20.3
(-3)
A 		49.5
(-1.6)
A 		143
(3)
A 		108.5
(1.3)
M 		123
avr 102.5
(0.8) 		83.4
(-0.5) 		46.7
(-3) 		95.4
(0.3) 		87.6
(-0.2) 		134.4
(3) 		88
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 33
1 2 3 4 range
A 28.3
(3)
A 		18.2
(-0)
A 		19.1
(0.3)
A 		8.2
(-3)
A 		20
B 22.6
(1.8)
A 		27.2
(3)
A 		22.9
(1.9)
A 		4.3
(-3)
A 		23
C 25.4
(1.4)
A 		26.4
(1.5)
A 		34.5
(3)
A 		1.3
(-3)
A 		33
avr 25.4
(3) 		23.9
(2.5) 		25.5
(3) 		4.6
(-3) 		21

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 44
1 2 3 4 5 6 range
A 14.8
(-2.5)
A 		32.9
(0.8)
A 		11.9
(-3)
A 		34.2
(1)
A 		23.2
(-1)
A 		45
(3)
A 		33
B 32.7
(1)
A 		29.1
(0.2)
A 		15.8
(-3)
A 		27
(-0.3)
A 		17.4
(-2.6)
A 		40.9
(3)
M 		25
C 49.3
(3)
A 		21.4
(-0.8)
A 		5.2
(-3)
A 		10
(-2.3)
A 		46.3
(2.6)
A 		36.3
(1.2)
M 		44
avr 32.3
(1.3) 		27.8
(0.4) 		11
(-3) 		23.7
(-0.4) 		29
(0.6) 		40.7
(3) 		30
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 190512_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.1779
Sequence Type Exemplar sequence
Representative Public ID F22G12.4 NCBI
Target Description F22G12.4 /REP_DB=WormBase Gene ID /WP=CE15891 /TR=O45398 /GB=CAB07368.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=Ank repeat (6 domains)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_060904(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_060904 NCBI Caenorhabditis elegans F22G12.4 (F22G12.4) mRNA, complete cds. 11/11 None
SNAP00000002514 ENSEMBL cdna:SNAP chromosome:CEL140:I:13163520:13169620:-1 11/11 None
GENEFINDER00000002520 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:13163520:13169620:-1 11/11 None
F22G12.4 ENSEMBL cdna:known chromosome:CEL140:I:13163392:13167447:-1 gene:F22G12.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:13163450-13169551(-) 100.0 100.0
Public Domain and Genome References
Gene Title Ank repeat (6 domains)
Ensembl F22G12.4
Entrez Gene 173180 Entrez gene
SwissProt O45398 EMBL-EBI
WormBase CE28920 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1587678_AT similar to Ankyrin repeat and FYVE domain protein 1 (Ankyrin repeats hooked to a zinc finger motif) cfa
CANINE_2:CFA.14901.1.A1_AT similar to Ankyrin repeat and FYVE domain protein 1 (Ankyrin repeats hooked to a zinc finger motif) cfa
CANINE_2:CFAAFFX.23418.1.S1_AT similar to Ankyrin repeat and FYVE domain protein 1 (Ankyrin repeats hooked to a zinc finger motif) cfa
CHICKEN:GGA.10459.1.S1_S_AT ankyrin repeat and FYVE domain containing 1 gga
CHICKEN:GGAAFFX.24251.1.S1_S_AT ankyrin repeat and FYVE domain containing 1 gga
HG-U133_PLUS_2:219868_S_AT ankyrin repeat and FYVE domain containing 1 hs
HG-U133A:219868_S_AT ankyrin repeat and FYVE domain containing 1 hs
HG-U133A_2:219868_S_AT ankyrin repeat and FYVE domain containing 1 hs
HU35KSUBA:RC_AA255490_AT ankyrin repeat and FYVE domain containing 1 hs
HU35KSUBA:R15268_AT ankyrin repeat and FYVE domain containing 1 hs
HU35KSUBB:RC_N30068_AT ankyrin repeat and FYVE domain containing 1 hs
U133_X3P:G7705277_3P_S_AT ankyrin repeat and FYVE domain containing 1 hs
U133_X3P:HS.301721.1.S1_3P_AT ankyrin repeat and FYVE domain containing 1 hs
U133_X3P:HS.128020.0.A1_3P_AT ankyrin repeat and FYVE domain containing 1 hs
HG-U133_PLUS_2:224900_AT ankyrin repeat and FYVE domain containing 1 hs
HG-U133B:224900_AT ankyrin repeat and FYVE domain containing 1 hs
HG-U95C:60011_AT ankyrin repeat and FYVE domain containing 1 hs
HG-U95C:64882_AT ankyrin repeat and FYVE domain containing 1 hs
HG-U95D:77279_AT ankyrin repeat and FYVE domain containing 1 hs
HG-U133_PLUS_2:1562495_AT Ankyrin repeat and FYVE domain containing 1 hs
HG-U133_PLUS_2:231308_AT Ankyrin repeat and FYVE domain containing 1 hs
HG-U133B:231308_AT Ankyrin repeat and FYVE domain containing 1 hs
HG-U133_PLUS_2:239073_AT Ankyrin repeat and FYVE domain containing 1 hs
HG-U133B:239073_AT Ankyrin repeat and FYVE domain containing 1 hs
HG-U95E:86545_AT Ankyrin repeat and FYVE domain containing 1 hs
HU35KSUBD:RC_AA456130_AT Ankyrin repeat and FYVE domain containing 1 hs
U133_X3P:HS.301721.0.A1_3P_AT Ankyrin repeat and FYVE domain containing 1 hs
U133_X3P:HS2.363174.1.A1_3P_AT Ankyrin repeat and FYVE domain containing 1 hs
MG-U74AV2:102054_AT ankyrin repeat and FYVE domain containing 1 mm
MOE430A:1417685_AT ankyrin repeat and FYVE domain containing 1 mm
MOUSE430A_2:1417685_AT ankyrin repeat and FYVE domain containing 1 mm
MOUSE430_2:1417685_AT ankyrin repeat and FYVE domain containing 1 mm
MOE430B:1443654_AT Ankyrin repeat and FYVE domain containing 1 (Ankfy1), mRNA mm
MOUSE430_2:1443654_AT Ankyrin repeat and FYVE domain containing 1 (Ankfy1), mRNA mm
MU19KSUBB:TC30544_AT Ankyrin repeat and FYVE domain containing 1 (Ankfy1), mRNA mm
MU19KSUBC:TC40109_AT Ankyrin repeat and FYVE domain containing 1 (Ankfy1), mRNA mm
RG-U34B:RC_AI045691_AT Ankyrin repeat and FYVE domain containing 1 (predicted) rn
RG-U34C:RC_AI176931_AT Ankyrin repeat and FYVE domain containing 1 (predicted) rn
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
8270 zinc ion binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB07368 Hypothetical protein F22G12.4 [Caenorhabditis elegans] ref|NP_493305.1| F22G12.4 [Caenorhabditis elegans] 0.0
blast CAE60704 Hypothetical protein CBG04367 [Caenorhabditis briggsae] 0.0
blast CAC70085 Hypothetical protein F22G12.6 [Caenorhabditis elegans] ref|NP_493306.1| F22G12.6 [Caenorhabditis elegans] 1.0E-141
Protein Domains
Database ID Description E-Value
Pfam IPR002110 EMBL-EBI Ankyrin 0.0042
Pfam IPR002110 EMBL-EBI Ankyrin 0.017
Pfam IPR002110 EMBL-EBI Ankyrin 2.3E-4
Pfam IPR002110 EMBL-EBI Ankyrin 1.9
Pfam IPR002110 EMBL-EBI Ankyrin 0.51
Pfam IPR002110 EMBL-EBI Ankyrin 9.8E-6
Pfam IPR002110 EMBL-EBI Ankyrin 10.0
Pfam IPR002110 EMBL-EBI Ankyrin 1.3
Pfam IPR002110 EMBL-EBI Ankyrin 0.0015
Pfam IPR002110 EMBL-EBI Ankyrin 0.048
Pfam IPR002110 EMBL-EBI Ankyrin 9.1E-5
Pfam IPR002110 EMBL-EBI Ankyrin 0.14
Pfam IPR002110 EMBL-EBI Ankyrin 3.4
Pfam IPR002110 EMBL-EBI Ankyrin 0.05
Pfam IPR002110 EMBL-EBI Ankyrin 0.03
Pfam IPR002110 EMBL-EBI Ankyrin 1.3E-4
Pfam IPR002110 EMBL-EBI Ankyrin 1.4
Pfam IPR002110 EMBL-EBI Ankyrin 1.1E-7
Pfam IPR000306 EMBL-EBI Zn-finger, FYVE type 2.1E-16
Pfam IPR000210 EMBL-EBI BTB/POZ domain 5.7E-14
Pfam IPR002110 EMBL-EBI Ankyrin 0.29
Pfam IPR002110 EMBL-EBI Ankyrin 0.017
Pfam IPR002110 EMBL-EBI Ankyrin 2.3E-4
Pfam IPR002110 EMBL-EBI Ankyrin 1.9
Pfam IPR002110 EMBL-EBI Ankyrin 0.51
Pfam IPR002110 EMBL-EBI Ankyrin 9.8E-6
Pfam IPR002110 EMBL-EBI Ankyrin 10.0
Pfam IPR002110 EMBL-EBI Ankyrin 1.3
Pfam IPR002110 EMBL-EBI Ankyrin 0.0015
Pfam IPR002110 EMBL-EBI Ankyrin 0.048
Pfam IPR002110 EMBL-EBI Ankyrin 9.1E-5
Pfam IPR002110 EMBL-EBI Ankyrin 0.14
Pfam IPR002110 EMBL-EBI Ankyrin 3.4
Pfam IPR002110 EMBL-EBI Ankyrin 0.05
Pfam IPR002110 EMBL-EBI Ankyrin 0.03
Pfam IPR002110 EMBL-EBI Ankyrin 1.3E-4
Pfam IPR002110 EMBL-EBI Ankyrin 1.4
Pfam IPR002110 EMBL-EBI Ankyrin 1.1E-7
Pfam IPR000306 EMBL-EBI Zn-finger, FYVE type 2.1E-16
Sequence
Target Sequence 
>C. ELEGANS:190512_S_AT
ccgagcagttgcagacagttccagaacaaatcgatacgcgaggaataaaatcggctacac
gtcactccacatctgcgctctactgacaatcgacaagctgccaaaacgaacgtcgagcag
tgacgtcatcgagctggtgctcatctatgcggaagaggaggcccaggcacagaatgagaa
acagtttgcgggatttattgatgcacgggatgcggatgggaatacggctctgatgattgc
ctattcacaggggaatgctggcgtttgcagatcccttctgaaacgccgagcatgcatggg
acaacggaataatggagatgtgaatgtattcacttatgaaactgccacaaagcagctgct
cttgggattactcgaatccctggaagccgaaccccgctggtcggacggtgacacttgcga
ctgcggcgcccgtttctcgctgacgtcacgaaaacatcactgtcgccattgtggtc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CCGAGCAGTTGCAGACAGTTCCAGA 535 263 2736 Antisense
CATCTGCGCTCTACTGACAATCGAC 49 211 2805 Antisense
GACGTCATCGAGCTGGTGCTCATCT 694 377 2857 Antisense
GGCTCTGATGATTGCCTATTCACAG 280 539 2961 Antisense
GGAATGCTGGCGTTTGCAGATCCCT 329 531 2987 Antisense
GAAACGCCGAGCATGCATGGGACAA 200 359 3015 Antisense
CAGCTGCTCTTGGGATTACTCGAAT 45 205 3088 Antisense
TACTCGAATCCCTGGAAGCCGAACC 193 645 3104 Antisense
CGCTGGTCGGACGGTGACACTTGCG 381 253 3130 Antisense
CGTTTCTCGCTGACGTCACGAAAAC 204 247 3166 Antisense
AAACATCACTGTCGCCATTGTGGTC 563 127 3187 Antisense
Sequence Source Affymetrix Proprietary Database