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[190502_s_at] serine/threonine kinase

Description F55C5.7 /REP_DB=WormBase Gene ID /WP=CE20874 /TR=Q20821 /GB=CAB01572.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster 6grp_highest_10_10 > 58      6grp_high1_10_10 > 94      4grp_highest_8_8 > 53      4grp_high_8_8 > 09      6grp_highest_nonorm > 73      6grp_total > 74      4grp_total > 23      6grp_high1_sub > In      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 253
1 2 3 4 range
A 425.8
(1.8)
P 		232.1
(-3)
P 		249.8
(-2.6)
P 		472.7
(3)
P 		241
B 484.6
(3)
P 		286.3
(-2.4)
P 		263.7
(-3)
P 		287.6
(-2.4)
P 		221
C 483.3
(3)
P 		244.8
(-3)
P 		255
(-2.7)
P 		442.2
(2)
P 		239
avr 464.6
(3) 		254.4
(-3) 		256.2
(-2.9) 		400.8
(1.2) 		210

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 234
1 2 3 4 5 6 range
A 388.8
(-3)
P 		475.5
(0.3)
P 		480.3
(0.5)
P 		507.5
(1.5)
P 		547.1
(3)
P 		488.3
(0.8)
P 		158
B 402.7
(-3)
P 		436.9
(-1.8)
P 		494.4
(0.2)
P 		548.4
(2.1)
P 		497.6
(0.3)
P 		574
(3)
P 		171
C 339.9
(-3)
P 		446.9
(-0.2)
P 		512.9
(1.5)
P 		481.3
(0.7)
P 		475.7
(0.5)
P 		570.6
(3)
P 		231
avr 377.1
(-3) 		453.1
(-0.3) 		495.9
(1.3) 		512.4
(1.9) 		506.8
(1.7) 		544.3
(3) 		167
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 110
1 2 3 4 range
A 155
(3)
P 		50.4
(-3)
P 		65.3
(-2.1)
P 		69.2
(-1.9)
P 		105
B 154.5
(3)
P 		70.7
(-2.4)
P 		61.1
(-3)
P 		61.3
(-3)
P 		93
C 160
(3)
P 		70.4
(-3)
P 		88.9
(-1.8)
P 		74.6
(-2.7)
P 		90
avr 156.5
(3) 		63.8
(-3) 		71.8
(-2.5) 		68.4
(-2.7) 		93

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 142
1 2 3 4 5 6 range
A 71.7
(-3)
P 		169.1
(3)
P 		104.6
(-1)
P 		128.7
(0.5)
P 		165.1
(2.8)
P 		118.9
(-0.1)
P 		97
B 140.1
(-1.7)
P 		145.4
(-1.4)
P 		120.1
(-3)
P 		145.2
(-1.4)
P 		202.2
(2.2)
P 		214.1
(3)
P 		94
C 126
(-1.1)
P 		136.4
(-0.5)
P 		130.5
(-0.9)
P 		96.8
(-3)
P 		153.9
(0.6)
P 		191
(3)
P 		94
avr 112.6
(-3) 		150.3
(0.6) 		118.4
(-2.4) 		123.6
(-1.9) 		173.7
(2.9) 		174.7
(3) 		62
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 190502_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.14699
Sequence Type Exemplar sequence
Representative Public ID F55C5.7 NCBI
Target Description F55C5.7 /REP_DB=WormBase Gene ID /WP=CE20874 /TR=Q20821 /GB=CAB01572.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073681(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073681 NCBI Caenorhabditis elegans F55C5.7 (F55C5.7) mRNA, complete cds. 11/11 None
SNAP00000005351 ENSEMBL cdna:SNAP chromosome:CEL140:V:12286806:12291190:-1 11/11 None
GENEFINDER00000005357 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:12286806:12291190:-1 11/11 None
F55C5.7 ENSEMBL cdna:known chromosome:CEL140:V:12286658:12291202:-1 gene:F55C5.7 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:12286805-12290883(-) 100.0 100.0
Public Domain and Genome References
Gene Title serine/threonine kinase
Ensembl F55C5.7
Entrez Gene 179685 Entrez gene
SwissProt Q20821 EMBL-EBI
WormBase CE31961 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFA.17654.1.S1_AT similar to ribosomal protein S6 kinase, 52kDa, polypeptide 1 cfa
CANINE_2:CFAAFFX.19275.1.S1_S_AT similar to ribosomal protein S6 kinase, 52kDa, polypeptide 1 cfa
CANINE_2:CFAAFFX.19288.1.S1_S_AT similar to ribosomal protein S6 kinase, 52kDa, polypeptide 1 cfa
DROSOPHILA_2:1628552_AT dm
DROSGENOME1:154268_AT dm
CHICKEN:GGAAFFX.20178.1.S1_AT ribosomal protein S6 kinase, 52kDa, polypeptide 1 gga
CHICKEN:GGAAFFX.6147.1.S1_AT ribosomal protein S6 kinase, 52kDa, polypeptide 1 gga
HG-U133_PLUS_2:218909_AT ribosomal protein S6 kinase, 52kDa, polypeptide 1 hs
HG-U133A:218909_AT ribosomal protein S6 kinase, 52kDa, polypeptide 1 hs
HG-FOCUS:218909_AT ribosomal protein S6 kinase, 52kDa, polypeptide 1 hs
HG-U133A_2:218909_AT ribosomal protein S6 kinase, 52kDa, polypeptide 1 hs
HU35KSUBA:RC_AA476448_AT ribosomal protein S6 kinase, 52kDa, polypeptide 1 hs
HU35KSUBC:RC_AA102718_AT ribosomal protein S6 kinase, 52kDa, polypeptide 1 hs
HU35KSUBD:RC_AA463847_AT ribosomal protein S6 kinase, 52kDa, polypeptide 1 hs
U133_X3P:G6912635_3P_AT ribosomal protein S6 kinase, 52kDa, polypeptide 1 hs
HG-U95B:44548_AT ribosomal protein S6 kinase, 52kDa, polypeptide 1 hs
HG-U95C:58944_S_AT ribosomal protein S6 kinase, 52kDa, polypeptide 1 hs
HG-U95B:59799_I_AT Ribosomal protein S6 kinase, 52kDa, polypeptide 1 hs
HG-U95B:59801_R_AT Ribosomal protein S6 kinase, 52kDa, polypeptide 1 hs
HG-U95C:63709_R_AT Ribosomal protein S6 kinase, 52kDa, polypeptide 1 hs
HG-U95E:72080_AT Ribosomal protein S6 kinase, 52kDa, polypeptide 1 hs
HU35KSUBB:RC_R18139_AT Ribosomal protein S6 kinase, 52kDa, polypeptide 1 hs
HU35KSUBD:RC_N64844_AT Ribosomal protein S6 kinase, 52kDa, polypeptide 1 hs
MU11KSUBA:AA682037_RC_AT ribosomal protein S6 kinase polypeptide 1 mm
MU11KSUBB:MSA.41961.0_S_AT ribosomal protein S6 kinase polypeptide 1 mm
MG-U74AV2:102875_AT ribosomal protein S6 kinase polypeptide 1 mm
MOE430A:1434563_AT ribosomal protein S6 kinase polypeptide 1 mm
MOUSE430A_2:1434563_AT ribosomal protein S6 kinase polypeptide 1 mm
MOUSE430_2:1434563_AT ribosomal protein S6 kinase polypeptide 1 mm
MG-U74CV2:133736_AT Ribosomal protein S6 kinase polypeptide 1, mRNA (cDNA clone MGC:67173 IMAGE:6812243) mm
RG-U34B:RC_AI030254_AT ribosomal protein S6 kinase, polypeptide 1 (predicted) rn
RG-U34C:RC_AI230495_AT ribosomal protein S6 kinase, polypeptide 1 (predicted) rn
RAE230A:1390689_AT ribosomal protein S6 kinase, polypeptide 1 (predicted) rn
RAT230_2:1390689_AT ribosomal protein S6 kinase, polypeptide 1 (predicted) rn
RAE230B:1383454_A_AT ribosomal protein S6 kinase, polypeptide 1 (predicted) rn
RAT230_2:1383454_A_AT ribosomal protein S6 kinase, polypeptide 1 (predicted) rn
RAE230B:1380302_AT Ribosomal protein S6 kinase, polypeptide 1 (predicted) rn
RAT230_2:1380302_AT Ribosomal protein S6 kinase, polypeptide 1 (predicted) rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
7242 intracellular signaling cascade inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB01572 Hypothetical protein F55C5.7 [Caenorhabditis elegans] ref|NP_506082.2| F55C5.7 [Caenorhabditis elegans] 0.0
blast CAE75440 Hypothetical protein CBG23434 [Caenorhabditis briggsae] 0.0
blast XP_419422 PREDICTED: similar to ribosomal protein S6 kinase, 52kDa, polypeptide 1; ribosomal protein S6 kinase, 52kD, polypeptide 1 [Gallus gallus] 1.0E-25
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 0.0016
Pfam IPR000719 EMBL-EBI Protein kinase 8.7E-13
Pfam IPR007330 EMBL-EBI MIT 7.2E-11
Pfam IPR001683 EMBL-EBI Phox-like 4.7E-17
Pfam IPR000719 EMBL-EBI Protein kinase 8.7E-13
Sequence
Target Sequence 
>C. ELEGANS:190502_S_AT
attgtttcattcttctttgttctacacgctgagcatcatgaatttattggtgacttcaac
gctgatgatattctcatagattctgatgggaacttactgatgacatatattggaagatgg
tatgaaacgaatcgacgaaaacggctgaccgatgggtattcggcaccggaaagctctcaa
tatggatgggaaccaactcctgaatctgatatctggactctcggggctttactttttgaa
atgctctgtggaaggtctctggctaatgcagcaccacatggagtgttaaggaatatggaa
ctaccgatcccagagaaagttgtagtttcatttgttgcaaaagatcttctgaatatgctt
ctagtaccaactcctgctcttcgaccatctcttgacgagattcgtgctcatccatttttc
cgtcacattgactggctcttatatgacaatccaacgtctccatcaacaccagctacagta
acccgaattcagtcaccaccaactcccccttctagcattgacattcccgaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATTGTTTCATTCTTCTTTGTTCTAC 253 5 1774 Antisense
CTTTGTTCTACACGCTGAGCATCAT 253 223 1788 Antisense
GGCTGACCGATGGGTATTCGGCACC 128 541 1916 Antisense
GAATCTGATATCTGGACTCTCGGGG 284 329 1975 Antisense
AAATGCTCTGTGGAAGGTCTCTGGC 420 119 2012 Antisense
AAGGTCTCTGGCTAATGCAGCACCA 50 161 2025 Antisense
TTTCCGTCACATTGACTGGCTCTTA 58 669 2190 Antisense
TATGACAATCCAACGTCTCCATCAA 23 657 2215 Antisense
CTCCATCAACACCAGCTACAGTAAC 431 235 2231 Antisense
TACAGTAACCCGAATTCAGTCACCA 320 643 2247 Antisense
CCCTTCTAGCATTGACATTCCCGAA 637 259 2280 Antisense
Sequence Source Affymetrix Proprietary Database