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[190488_at] acetolactate synthase

Description T26C12.1 /REP_DB=WormBase Gene ID /WP=CE26009 /TR=O61856 /GB=AAC17553.2 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=acetolactate synthase
Cluster 6grp_highest_10_10 > 50      6grp_high1_10_10 > 06      4grp_highest_8_8 > 25      4grp_high_8_8 > 60      6grp_highest_nonorm > 20      6grp_total > 06      4grp_total > 60      6grp_highest_sub > De      6grp_high1_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 926
1 2 3 4 range
A 1172.2
(3)
P 		1119
(2.5)
P 		1145.5
(2.8)
P 		508.2
(-3)
P 		664
B 1203
(1.6)
P 		1108
(1)
P 		1423.6
(3)
P 		497.3
(-3)
P 		926
C 1049.1
(1)
P 		1298.8
(2.9)
P 		1310.5
(3)
P 		521.2
(-3)
P 		789
avr 1141.4
(1.8) 		1175.3
(2.1) 		1293.2
(3) 		508.9
(-3) 		784

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1108
1 2 3 4 5 6 range
A 1244.2
(3)
P 		1145.9
(1.6)
P 		1087.7
(0.8)
P 		933
(-1.3)
P 		813.1
(-3)
P 		826.7
(-2.8)
P 		431
B 1691.3
(3)
P 		1210.1
(-0.1)
P 		1328.2
(0.6)
P 		950.7
(-1.8)
P 		892.9
(-2.2)
P 		766.2
(-3)
P 		925
C 1829.7
(3)
P 		1077.4
(-1.1)
P 		1039.4
(-1.3)
P 		953.6
(-1.7)
P 		849.9
(-2.3)
P 		721.3
(-3)
P 		1108
avr 1588.4
(3) 		1144.5
(-0.3) 		1151.8
(-0.2) 		945.8
(-1.7) 		852
(-2.4) 		771.4
(-3) 		817
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 382
1 2 3 4 range
A 426.8
(3)
P 		242.9
(-0.1)
P 		299.5
(0.8)
P 		74.4
(-3)
P 		352
B 383.6
(3)
P 		273.7
(0.6)
P 		329.9
(1.8)
P 		106
(-3)
P 		278
C 347.3
(1.2)
P 		373.4
(1.6)
P 		456.7
(3)
P 		87.9
(-3)
P 		369
avr 385.9
(3) 		296.7
(1.2) 		362
(2.5) 		89.4
(-3) 		297

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 486
1 2 3 4 5 6 range
A 229.4
(-2.2)
P 		407.6
(3)
P 		236.9
(-2)
P 		236.6
(-2)
P 		245.4
(-1.7)
P 		201.3
(-3)
P 		206
B 588.5
(3)
P 		402.8
(-0.3)
P 		322.5
(-1.7)
P 		251.8
(-3)
P 		362.8
(-1)
P 		285.7
(-2.4)
P 		337
C 678.2
(3)
P 		328.7
(-1.3)
P 		264.6
(-2.1)
P 		191.8
(-3)
P 		275
(-2)
P 		241.5
(-2.4)
P 		486
avr 498.7
(3) 		379.7
(0.4) 		274.7
(-1.9) 		226.7
(-3) 		294.4
(-1.5) 		242.8
(-2.6) 		272
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190488_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.10693
Sequence Type Exemplar sequence
Representative Public ID T26C12.1 NCBI
Target Description T26C12.1 /REP_DB=WormBase Gene ID /WP=CE26009 /TR=O61856 /GB=AAC17553.2 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=acetolactate synthase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_067905(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_067905 NCBI Caenorhabditis elegans T26C12.1 (T26C12.1) mRNA, complete cds. 11/11 None
SNAP00000018487 ENSEMBL cdna:SNAP chromosome:CEL140:IV:3258917:3263297:1 11/11 None
GENEFINDER00000018493 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:3258917:3263297:1 11/11 None
T26C12.1.2 ENSEMBL cdna:known chromosome:CEL140:IV:3258904:3263485:1 gene:T26C12.1 11/11 None
T26C12.1.1 ENSEMBL cdna:known chromosome:CEL140:IV:3258906:3263485:1 gene:T26C12.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:3258922-3263303(+) 100.0 100.0
Public Domain and Genome References
Gene Title acetolactate synthase
Ensembl T26C12.1
Entrez Gene 177095 Entrez gene
SwissProt O61856 EMBL-EBI
WormBase CE26009 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1583626_S_AT similar to ilvB (bacterial acetolactate synthase)-like isoform 1 cfa
CANINE_2:CFA.11564.1.A1_AT similar to ilvB (bacterial acetolactate synthase)-like isoform 1 cfa
CANINE_2:CFA.21461.1.S1_S_AT similar to ilvB (bacterial acetolactate synthase)-like isoform 1 cfa
CANINE_2:CFAAFFX.24752.1.S1_S_AT similar to ilvB (bacterial acetolactate synthase)-like isoform 1 cfa
CANINE_2:CFAAFFX.24760.1.S1_S_AT similar to ilvB (bacterial acetolactate synthase)-like isoform 1 cfa
HG-U133_PLUS_2:216270_AT ilvB (bacterial acetolactate synthase)-like hs
HG-U133A_2:216270_AT ilvB (bacterial acetolactate synthase)-like hs
HG-U133A:216270_AT ilvB (bacterial acetolactate synthase)-like hs
HG-U133_PLUS_2:210624_S_AT ilvB (bacterial acetolactate synthase)-like hs
HG-U133A:210624_S_AT ilvB (bacterial acetolactate synthase)-like hs
HG-FOCUS:210624_S_AT ilvB (bacterial acetolactate synthase)-like hs
HG-U133A_2:210624_S_AT ilvB (bacterial acetolactate synthase)-like hs
HUGENEFL:U61263_AT ilvB (bacterial acetolactate synthase)-like hs
HG-U133A:202993_AT ilvB (bacterial acetolactate synthase)-like hs
HG-U133_PLUS_2:202993_AT ilvB (bacterial acetolactate synthase)-like hs
HG-U133A_2:202993_AT ilvB (bacterial acetolactate synthase)-like hs
U133_X3P:G5803041_3P_A_AT ilvB (bacterial acetolactate synthase)-like hs
U133_X3P:HS.9291.1.A1_3P_AT ilvB (bacterial acetolactate synthase)-like hs
HG-U95AV2:37690_AT ilvB (bacterial acetolactate synthase)-like hs
HG-U95D:72790_AT ilvB (bacterial acetolactate synthase)-like hs
MU11KSUBB:W42062_S_AT ilvB (bacterial acetolactate synthase)-like mm
MG-U74AV2:94428_AT ilvB (bacterial acetolactate synthase)-like mm
MG-U74AV2:161738_F_AT ilvB (bacterial acetolactate synthase)-like mm
MG-U74CV2:170913_F_AT ilvB (bacterial acetolactate synthase)-like mm
MG-U74CV2:170026_AT ilvB (bacterial acetolactate synthase)-like mm
MOE430B:1454658_AT ilvB (bacterial acetolactate synthase)-like mm
MOUSE430_2:1454658_AT ilvB (bacterial acetolactate synthase)-like mm
MOE430B:1456300_AT IlvB (bacterial acetolactate synthase)-like, mRNA (cDNA clone MGC:67151 IMAGE:5718157) mm
MOUSE430_2:1456300_AT IlvB (bacterial acetolactate synthase)-like, mRNA (cDNA clone MGC:67151 IMAGE:5718157) mm
MG-U74CV2:168449_I_AT IlvB (bacterial acetolactate synthase)-like, mRNA (cDNA clone MGC:67151 IMAGE:5718157) mm
MG-U74CV2:168728_AT IlvB (bacterial acetolactate synthase)-like, mRNA (cDNA clone MGC:67151 IMAGE:5718157) mm
MG-U74CV2:169385_R_AT IlvB (bacterial acetolactate synthase)-like, mRNA (cDNA clone MGC:67151 IMAGE:5718157) mm
RG-U34C:RC_AI111854_AT ilvB (bacterial acetolactate synthase)-like (predicted) rn
RAE230A:1373512_AT ilvB (bacterial acetolactate synthase)-like (predicted) rn
RAT230_2:1373512_AT ilvB (bacterial acetolactate synthase)-like (predicted) rn
RAE230B:1397521_AT ilvB (bacterial acetolactate synthase)-like (predicted) rn
RAT230_2:1397521_AT ilvB (bacterial acetolactate synthase)-like (predicted) rn
RAE230A:1389677_AT IlvB (bacterial acetolactate synthase)-like (predicted) rn
RAT230_2:1389677_AT IlvB (bacterial acetolactate synthase)-like (predicted) rn
RG-U34C:RC_AA818650_AT IlvB (bacterial acetolactate synthase)-like (predicted) rn
RG-U34B:RC_AA956942_AT IlvB (bacterial acetolactate synthase)-like (predicted) rn
Protein Similarities
Method ID Description E-Value
blast NP_500306 T26C12.1 [Caenorhabditis elegans] gb|AAC17553.2| Hypothetical protein T26C12.1 [Caenorhabditis elegans] 0.0
blast CAE59896 Hypothetical protein CBG03380 [Caenorhabditis briggsae] 0.0
blast AAH68362 Ilvbl protein [Danio rerio] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR000399 EMBL-EBI Pyruvate decarboxylase 1.9E-14
Pfam IPR000399 EMBL-EBI Pyruvate decarboxylase 2.3E-34
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_500306.1 1 2-21
T26C12.1.2 1 2-21
T26C12.1.1 1 2-21
SNAP00000018487 1 2-21
GENEFINDER00000018493 1 2-21
Sequence
Target Sequence 
>C. ELEGANS:190488_AT
gaatggcttcttgaatccgctgaatttcctgagaactctcgatcaatcacttcccgacga
tgcgatccttgtggccgatggaggtgactttgtcggttcggctgcctacattgttcgccc
acgaggaccacttcaatggctcgatcctggagcattcggaacacttggagtcggtggagg
ttttgctcttggagccaagactgtctatccgaagcgtccggtgtacattatttggggaga
cggatcctgcggatattcgttgatggaatatgacacttttgctagacacaaattgccagt
tatcggaattgttggaaatgacgcgtgctggacacaaatcgccagagaacaagtgccaat
gttccagagctctgtggctgttgatttggctagaactcgctacgacaacgtcgccaaatc
actcggatcctggggagagaccatcgatgaatcgaacgccgattcggctcgaaagatcct
tgatgaagctctcgctgtctgccgatcaggagaacaatcggctctcgttaatgtgctcat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAATGGCTTCTTGAATCCGCTGAAT 416 333 1356 Antisense
TGGAGGTGACTTTGTCGGTTCGGCT 301 549 1434 Antisense
AGGACCACTTCAATGGCTCGATCCT 368 55 1479 Antisense
GAGTCGGTGGAGGTTTTGCTCTTGG 292 399 1523 Antisense
AGACTGTCTATCCGAAGCGTCCGGT 325 69 1553 Antisense
GGATCCTGCGGATATTCGTTGATGG 159 513 1597 Antisense
CAAGTGCCAATGTTCCAGAGCTCTG 601 183 1705 Antisense
CTAGAACTCGCTACGACAACGTCGC 238 225 1745 Antisense
CGCCAAATCACTCGGATCCTGGGGA 314 257 1767 Antisense
CTCGCTGTCTGCCGATCAGGAGAAC 362 233 1846 Antisense
AATCGGCTCTCGTTAATGTGCTCAT 483 169 1871 Antisense
Sequence Source Affymetrix Proprietary Database