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[190485_s_at] Na/Ca, K antiporter

Description C07A9.11 /REP_DB=WormBase Gene ID /WP=CE00501 /TR=SW:P34322 /GB=CAA82341.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=Na-Ca, K antiporter
Cluster 6grp_highest_10_10 > 25      6grp_high1_10_10 > 40      4grp_highest_8_8 > 37      4grp_high_8_8 > 01      6grp_highest_nonorm > 90      6grp_total > 41      4grp_total > 15      6grp_highest_sub > 03      6grp_cgc > 82      6grp_high1_sub > 03      6grp_cgc_sub > 03      6grp_total_sub > Hat      6grp_rule_based > S3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 129
1 2 3 4 range
A 154.4
(3)
P 		67
(-3)
P 		103.3
(-0.5)
P 		147.4
(2.5)
P 		87
B 119.9
(0.2)
P 		50
(-3)
P 		73.7
(-1.9)
P 		179.4
(3)
P 		129
C 152.2
(3)
P 		84.4
(-3)
P 		103.8
(-1.3)
P 		130.4
(1.1)
P 		68
avr 142.2
(2.3) 		67.1
(-3) 		93.6
(-1.1) 		152.4
(3) 		85

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 81
1 2 3 4 5 6 range
A 88.9
(0.2)
P 		87.3
(0.1)
P 		126.3
(3)
P 		96.2
(0.8)
P 		69.6
(-1.2)
P 		45.3
(-3)
P 		81
B 88.2
(1)
P 		107
(3)
P 		92.3
(1.5)
P 		79.7
(0.2)
P 		49.5
(-3)
P 		67.7
(-1.1)
P 		58
C 68.8
(-1.5)
P 		87.7
(0.1)
P 		122.7
(3)
P 		100.4
(1.1)
P 		51.5
(-3)
P 		64
(-1.9)
P 		71
avr 82
(-0.4) 		94
(0.9) 		113.8
(3) 		92.1
(0.7) 		56.9
(-3) 		59
(-2.8) 		57
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 44
1 2 3 4 range
A 56.2
(3)
P 		14.5
(-3)
P 		27
(-1.2)
P 		21.6
(-2)
P 		42
B 38.2
(3)
P 		12.3
(-3)
P 		17.1
(-1.9)
P 		38.2
(3)
P 		26
C 50.4
(3)
P 		24.3
(-2.5)
P 		36.2
(0)
P 		22
(-3)
P 		28
avr 48.3
(3) 		17
(-3) 		26.8
(-1.1) 		27.3
(-1) 		31

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 25
1 2 3 4 5 6 range
A 16.4
(-1.4)
P 		31
(3)
P 		27.5
(2)
P 		24.4
(1)
P 		21
(0)
P 		11
(-3)
P 		20
B 30.7
(1.1)
P 		35.6
(3)
P 		22.4
(-2.1)
P 		21.1
(-2.6)
P 		20.1
(-3)
P 		25.3
(-1)
P 		16
C 25.5
(0.6)
P 		26.8
(1.2)
P 		31.2
(3)
P 		20.2
(-1.6)
P 		16.7
(-3)
P 		21.4
(-1.1)
P 		15
avr 24.2
(-0.5) 		31.1
(3) 		27
(0.9) 		21.9
(-1.6) 		19.3
(-2.9) 		19.2
(-3) 		12
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 190485_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.7073
Sequence Type Exemplar sequence
Representative Public ID C07A9.11 NCBI
Target Description C07A9.11 /REP_DB=WormBase Gene ID /WP=CE00501 /TR=SW:P34322 /GB=CAA82341.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=Na-Ca, K antiporter
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_066746(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_066746 NCBI Caenorhabditis elegans Na/Ca eXchangers family member (ncx-7) (ncx-7) mRNA, complete cds. 11/11 None
GENEFINDER00000039345 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:9715041:9720178:-1 11/11 None
SNAP00000039333 ENSEMBL cdna:SNAP chromosome:CEL140:III:9715952:9719721:-1 11/11 None
C07A9.11 ENSEMBL cdna:known chromosome:CEL140:III:9715780:9720235:-1 gene:C07A9.11 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:9715947-9719071(-) 100.0 100.0
Public Domain and Genome References
Gene Title Na/Ca, K antiporter
Gene Symbol ncx-7
Ensembl C07A9.11
Entrez Gene 176370 Entrez gene
SwissProt P34322 EMBL-EBI
WormBase CE33969 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:250054_AT cation exchanger, putative (CAX7) at
DROSOPHILA_2:1640152_AT dm
DROSGENOME1:147331_AT dm
CHICKEN:GGA.15388.1.S1_AT similar to solute carrier family 24 member 6; sodium/potassium/calcium exchanger gga
CHICKEN:GGAAFFX.22537.1.S1_AT similar to solute carrier family 24 member 6; sodium/potassium/calcium exchanger gga
HG-U133_PLUS_2:218749_S_AT solute carrier family 24 (sodium/potassium/calcium exchanger), member 6 hs
HG-U133A:218749_S_AT solute carrier family 24 (sodium/potassium/calcium exchanger), member 6 hs
HG-U133A_2:218749_S_AT solute carrier family 24 (sodium/potassium/calcium exchanger), member 6 hs
HU35KSUBA:RC_AA461505_AT solute carrier family 24 (sodium/potassium/calcium exchanger), member 6 hs
HU35KSUBA:RC_AA427627_AT solute carrier family 24 (sodium/potassium/calcium exchanger), member 6 hs
U133_X3P:G13376448_3P_A_AT solute carrier family 24 (sodium/potassium/calcium exchanger), member 6 hs
U133_X3P:HS.286194.0.A1_3P_A_AT solute carrier family 24 (sodium/potassium/calcium exchanger), member 6 hs
HG-U133_PLUS_2:222727_S_AT solute carrier family 24 (sodium/potassium/calcium exchanger), member 6 hs
HG-U133B:222727_S_AT solute carrier family 24 (sodium/potassium/calcium exchanger), member 6 hs
HG-U95B:51207_AT solute carrier family 24 (sodium/potassium/calcium exchanger), member 6 hs
HG-U95B:57862_AT solute carrier family 24 (sodium/potassium/calcium exchanger), member 6 hs
MG-U74BV2:110688_AT solute carrier family 24 (sodium/potassium/calcium exchanger), member 6 mm
MOE430A:1417811_AT solute carrier family 24 (sodium/potassium/calcium exchanger), member 6 mm
MOUSE430A_2:1417811_AT solute carrier family 24 (sodium/potassium/calcium exchanger), member 6 mm
MOUSE430_2:1417811_AT solute carrier family 24 (sodium/potassium/calcium exchanger), member 6 mm
RG-U34B:RC_AA998949_AT similar to sodium/calcium exchanger protein rn
RAE230A:1376936_AT similar to sodium/calcium exchanger protein rn
RAT230_2:1376936_AT similar to sodium/calcium exchanger protein rn
Gene Ontology
GO Cellular Component (view graph)
ID Description Evidence Links
16021 integral to membrane inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA82341 Hypothetical protein C07A9.11 [Caenorhabditis elegans] ref|NP_499147.2| Na/Ca eXchangers family member (ncx-7) [Caenorhabditis elegans] sp|P34322|NCX7_CAEEL Putative sodium/calcium exchanger 7 precursor (Na(+)/Ca(2+)-exchange protein 7) 0.0
blast CAE65148 Hypothetical protein CBG10014 [Caenorhabditis briggsae] 0.0
blast AAB65309 Na/ca exchangers protein 9 [Caenorhabditis elegans] ref|NP_504342.1| Na/Ca eXchangers family member (ncx-9) [Caenorhabditis elegans] 1.0E-159
Protein Domains
Database ID Description E-Value
Pfam IPR004837 EMBL-EBI Sodium/calcium exchanger membrane region 3.9E-30
Pfam IPR004837 EMBL-EBI Sodium/calcium exchanger membrane region 7.6E-35
Pfam IPR004837 EMBL-EBI Sodium/calcium exchanger membrane region 3.9E-30
Pfam IPR004837 EMBL-EBI Sodium/calcium exchanger membrane region 7.6E-35
Pfam IPR004837 EMBL-EBI Sodium/calcium exchanger membrane region 3.9E-30
Pfam IPR004837 EMBL-EBI Sodium/calcium exchanger membrane region 7.6E-35
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_499147.2 12 15-37,103-125,183-205,218-236,241-263,470-489,499-518,531-553,568-590,597-619,634-656,668-690
C07A9.11 12 15-37,103-125,183-205,218-236,241-263,470-489,499-518,531-553,568-590,597-619,634-656,668-690
GENEFINDER00000039345 12 4-21,84-106,164-186,199-217,222-244,451-470,480-499,512-534,549-571,578-600,615-637,650-672
SNAP00000039333 11 33-55,113-135,148-166,171-193,395-414,424-443,456-478,493-515,522-544,559-581,593-615
Sequence
Target Sequence 
>C. ELEGANS:190485_S_AT
tttcctcgaaactccattttctggaagtcctggtctctgggtatacggtttggcagtttc
aattgtacttgctattcttattatggtttttactgaattgagtgttcaaccgaaatacta
taaagaaatctactcatattctggattcattatgtcaattgcatggatttatttaatttc
ttcggaagttgtaaatgttgtaacaatgcttggagttgtttcaagagtatcacatgaagt
acttggtctaacaattcttgcatggagtaatagtattggagacttgattgctgatgtttc
agttgttaaacaaggttatccgagaatggctatggctgcagctattggaggtcctttatt
taatcttttgatgggatttggattgccattcacaattgctaaattacaagggaaatatat
ttcaatgacaattaatccaacctatcgccttcttatccttttcttggcgatttctctact
tgccacgttgataggaatcccagttcaaaaattccgtcttcaacgtccacatgcggcagt
ttta

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTTCCTCGAAACTCCATTTTCTGGA 151 623 1173 Antisense
ATTTTCTGGAAGTCCTGGTCTCTGG 196 15 1188 Antisense
TGGTCTCTGGGTATACGGTTTGGCA 283 549 1203 Antisense
ATTGTACTTGCTATTCTTATTATGG 241 3 1234 Antisense
ATGGCTGCAGCTATTGGAGGTCCTT 90 53 1504 Antisense
TGACAATTAATCCAACCTATCGCCT 588 571 1598 Antisense
TCGCCTTCTTATCCTTTTCTTGGCG 493 599 1617 Antisense
TTTTCTTGGCGATTTCTCTACTTGC 179 677 1631 Antisense
TACTTGCCACGTTGATAGGAATCCC 681 643 1649 Antisense
GAATCCCAGTTCAAAAATTCCGTCT 697 321 1667 Antisense
TCAACGTCCACATGCGGCAGTTTTA 272 631 1692 Antisense
Sequence Source Affymetrix Proprietary Database