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[190479_s_at] hedgehog-like protein

Description T05C12.10 /REP_DB=WormBase Gene ID /WP=CE02313 /TR=Q21535 /GB=CAA91313.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=hedgehog-like protein
Cluster 6grp_high1_10_10 > 80      6grp_total > 82      4grp_total > 49      6grp_cgc > 74      6grp_high1_sub > 02_03_04_05      6grp_cgc_sub > 02_03_04_05      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1255
1 2 3 4 range
A 8.5
(-3)
A 		1156.9
(2.8)
P 		1204.4
(3)
P 		7.8
(-3)
A 		1197
B 9.6
(-3)
A 		886.1
(3)
P 		831.8
(2.6)
P 		42.9
(-2.8)
A 		877
C 45.4
(-2.8)
A 		884.8
(1.2)
P 		1262.4
(3)
P 		11.4
(-3)
A 		1251
avr 21.2
(-3) 		975.9
(2.3) 		1099.5
(3) 		20.7
(-3) 		1079

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 751
1 2 3 4 5 6 range
A 341.5
(-1.3)
P 		761.8
(3)
P 		453.3
(-0.2)
P 		664
(2)
P 		754.1
(2.9)
P 		181
(-3)
M 		581
B 373.4
(-1.4)
P 		785.9
(2.7)
P 		558.7
(0.5)
P 		817.8
(3)
P 		596.3
(0.8)
P 		206.8
(-3)
P 		611
C 297.3
(-2.1)
P 		931.8
(3)
P 		492.9
(-0.6)
P 		826.5
(2.1)
P 		533
(-0.2)
P 		190.2
(-3)
P 		742
avr 337.4
(-1.6) 		826.5
(3) 		501.6
(-0.1) 		769.4
(2.5) 		627.8
(1.1) 		192.7
(-3) 		634
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 439
1 2 3 4 range
A 3.1
(-3)
A 		251.1
(1.8)
P 		314.8
(3)
P 		1.1
(-3)
A 		314
B 3.1
(-3)
A 		218.8
(3)
P 		192.8
(2.3)
P 		9.2
(-2.8)
A 		216
C 15
(-2.8)
A 		254.4
(0.5)
P 		440
(3)
P 		1.9
(-3)
A 		438
avr 7.1
(-2.9) 		241.4
(1.6) 		315.9
(3) 		4.1
(-3) 		312

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 240
1 2 3 4 5 6 range
A 63
(-2.5)
P 		270.9
(3)
P 		98.7
(-1.6)
P 		168.4
(0.3)
P 		227.6
(1.9)
P 		44.1
(-3)
M 		227
B 129.9
(-1.3)
P 		261.6
(3)
P 		135.7
(-1.1)
P 		216.6
(1.5)
P 		242.3
(2.4)
P 		77.1
(-3)
P 		185
C 110.2
(-1.7)
P 		284.3
(3)
P 		125.5
(-1.3)
P 		166.2
(-0.2)
P 		172.5
(-0)
P 		63.7
(-3)
P 		221
avr 101
(-1.9) 		272.3
(3) 		120
(-1.3) 		183.7
(0.5) 		214.1
(1.3) 		61.6
(-3) 		211
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 190479_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.2917
Sequence Type Exemplar sequence
Representative Public ID T05C12.10 NCBI
Target Description T05C12.10 /REP_DB=WormBase Gene ID /WP=CE02313 /TR=Q21535 /GB=CAA91313.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=hedgehog-like protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_063324(9)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_063324 NCBI Caenorhabditis elegans QUAhog (hedgehog related) family member (qua-1) (qua-1) mRNA, complete cds. 9/11 None
SNAP00000006395 ENSEMBL cdna:SNAP chromosome:CEL140:II:8201777:8203583:1 9/11 None
T05C12.10 ENSEMBL cdna:known chromosome:CEL140:II:8198725:8203910:1 gene:T05C12.10 9/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
GENEFINDER00000006409 8/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:8198721-8203580(+) 84.55 100.0
Public Domain and Genome References
Gene Title hedgehog-like protein
Gene Symbol qua-1
Ensembl T05C12.10
Entrez Gene 174319 Entrez gene
SwissProt Q21535 EMBL-EBI
WormBase CE34989 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
7154 cell communication inferred from electronic annotation QuickGO AmiGO
7275 development inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
8233 peptidase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA91313 Hypothetical protein T05C12.10 [Caenorhabditis elegans] emb|CAA90265.2| Hypothetical protein T05C12.10 [Caenorhabditis elegans] ref|NP_495725.2| QUAhog (hedgehog related) family member (qua-1) [Caenorhabditis elegans] 1.0E-153
blast CAA91313 Hypothetical protein T05C12.10 [Caenorhabditis elegans] emb|CAA90265.2| Hypothetical protein T05C12.10 [Caenorhabditis elegans] ref|NP_495725.2| QUAhog (hedgehog related) family member (qua-1) [Caenorhabditis elegans] 1.0E-152
blast CAE57710 Hypothetical protein CBG00717 [Caenorhabditis briggsae] 1.0E-133
blast CAE57710 Hypothetical protein CBG00717 [Caenorhabditis briggsae] 1.0E-103
blast CAB04547 Hypothetical protein K02E2.2 [Caenorhabditis elegans] ref|NP_507923.1| GRounDhog (hedgehog-like family) family member (grd-11) [Caenorhabditis elegans] 2.0E-20
blast CAB04547 Hypothetical protein K02E2.2 [Caenorhabditis elegans] ref|NP_507923.1| GRounDhog (hedgehog-like family) family member (grd-11) [Caenorhabditis elegans] 5.0E-20
Protein Domains
Database ID Description E-Value
Pfam IPR001767 EMBL-EBI Peptidase C46, hedgehog protein, hint region 6.7E-40
Pfam IPR001767 EMBL-EBI Peptidase C46, hedgehog protein, hint region 6.7E-40
Sequence
Target Sequence 
>C. ELEGANS:190479_S_AT
gaaagctctctctgactggaagacatttgctcccagttgcagaatgtagtcaagttgaac
aatacacaatgaatccagatggaattgatgtagctatgagagaatcgaaatatgctgaaa
aagcaagaaagggagaatgtgtactttctattgatgagtcaggtgaagtcattgctgatg
aaattgttagggtaggaagaatgaccaatgttggaatttattctccaatgacagttgaag
gaagcttaattgttgatggtgtactttcatcttgtttctcacatttggaatcccattctg
ctcacaagctcattttcgatttcatttactatgtctacaatgcgtttggactattaaaca
gagccaaagggcctgcctaccttcaagcccaccgagctctccgtccgccaaagtacacaa
aacatgtttttttgttttttaatcgagcgttcaacagattaattgaattaaaatcaaacc
acgtggatcttcaaccaatcccaacattcgtcagttttgctcaat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAAAGCTCTCTCTGACTGGAAGACA 620 359 3080 Antisense
TGGAAGACATTTGCTCCCAGTTGCA 397 547 3096 Antisense
TGGTGTACTTTCATCTTGTTTCTCA 209 553 3336 Antisense
ACATTTGGAATCCCATTCTGCTCAC 535 105 3360 Antisense
TGCTCACAAGCTCATTTTCGATTTC 117 581 3378 Antisense
GTCTACAATGCGTTTGGACTATTAA 101 469 3412 Antisense
AAACAGAGCCAAAGGGCCTGCCTAC 43 129 3435 Antisense
TCCGTCCGCCAAAGTACACAAAACA 36 595 3479 Antisense
AAACCACGTGGATCTTCAACCAATC 521 125 3555 Antisense
GGATCTTCAACCAATCCCAACATTC 469 511 3564 Antisense
CCAACATTCGTCAGTTTTGCTCAAT 205 277 3580 Antisense
Sequence Source Affymetrix Proprietary Database