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[190478_at] acyl-CoA dehydrogenase

Description C37A2.3 /REP_DB=WormBase Gene ID /WP=CE08612 /TR=O01502 /GB=AAB52448.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=acyl-CoA dehydrogenase
Cluster 6grp_total > 87      4grp_total > 17      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 40
1 2 3 4 range
A 3.1
(-2.9)
A 		5.4
(-2.5)
A 		2.3
(-3)
A 		40.8
(3)
A 		39
B 2.6
(-3)
A 		30.4
(3)
A 		23.4
(1.5)
A 		30.5
(3)
A 		28
C 1.2
(-3)
A 		4.9
(-2.4)
A 		7.8
(-1.9)
A 		37.3
(3)
A 		36
avr 2.3
(-3) 		13.6
(-1) 		11.2
(-1.4) 		36.2
(3) 		34

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 65
1 2 3 4 5 6 range
A 26.2
(-0.8)
A 		2.7
(-3)
A 		3.3
(-2.9)
A 		6.2
(-2.7)
A 		23
(-1.1)
A 		66.2
(3)
P 		64
B 4.7
(-3)
A 		16
(-1.6)
A 		18.4
(-1.3)
A 		5.9
(-2.9)
A 		38.1
(1)
M 		54.5
(3)
A 		50
C 4.9
(-2.7)
A 		1.7
(-3)
A 		12.7
(-1.9)
A 		62.8
(3)
A 		39.8
(0.7)
A 		61.8
(2.9)
P 		61
avr 11.9
(-2.4) 		6.8
(-3) 		11.5
(-2.5) 		25
(-1) 		33.6
(-0) 		60.8
(3) 		54
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 7
1 2 3 4 range
A 1.1
(-2.4)
A 		1.2
(-2.3)
A 		0.6
(-3)
A 		6
(3)
A 		5
B 0.8
(-3)
A 		7.5
(3)
A 		5.4
(1.1)
A 		6.5
(2.1)
A 		7
C 0.4
(-3)
A 		1.4
(-2)
A 		2.7
(-0.7)
A 		6.3
(3)
A 		6
avr 0.8
(-3) 		3.4
(-0.2) 		2.9
(-0.7) 		6.3
(3) 		6

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 20
1 2 3 4 5 6 range
A 4.8
(-1.4)
A 		1
(-2.9)
A 		0.7
(-3)
A 		1.6
(-2.6)
A 		7
(-0.5)
A 		16.1
(3)
P 		15
B 1.6
(-3)
A 		5.3
(-1.8)
A 		4.5
(-2.1)
A 		1.6
(-3)
A 		15.5
(1.5)
M 		20.3
(3)
A 		19
C 1.8
(-2.6)
A 		0.5
(-3)
A 		3.2
(-2.2)
A 		12.6
(0.6)
A 		12.9
(0.7)
A 		20.7
(3)
P 		20
avr 2.7
(-2.9) 		2.3
(-3) 		2.8
(-2.8) 		5.3
(-1.9) 		11.8
(0.4) 		19
(3) 		17
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190478_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.1104
Sequence Type Exemplar sequence
Representative Public ID C37A2.3 NCBI
Target Description C37A2.3 /REP_DB=WormBase Gene ID /WP=CE08612 /TR=O01502 /GB=AAB52448.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=acyl-CoA dehydrogenase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059541(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_059541 NCBI Caenorhabditis elegans C37A2.3 (C37A2.3) mRNA, complete cds. 11/11 None
GENEFINDER00000014190 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:6788955:6795204:1 11/11 None
SNAP00000014177 ENSEMBL cdna:SNAP chromosome:CEL140:I:6793042:6795204:1 11/11 None
C37A2.3 ENSEMBL cdna:known chromosome:CEL140:I:6793015:6795204:1 gene:C37A2.3 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:6792970-6795133(+) 100.0 100.0
Public Domain and Genome References
Gene Title acyl-CoA dehydrogenase
Ensembl C37A2.3
Entrez Gene 172400 Entrez gene
SwissProt O01502 EMBL-EBI
WormBase CE08612 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6118 electron transport inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3995 acyl-CoA dehydrogenase activity inferred from electronic annotation QuickGO AmiGO
16491 oxidoreductase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB52448 Hypothetical protein C37A2.3 [Caenorhabditis elegans] ref|NP_491942.1| C37A2.3 [Caenorhabditis elegans] 0.0
blast AAA27913 Hypothetical protein C02D5.1 [Caenorhabditis elegans] ref|NP_498885.1| C02D5.1 [Caenorhabditis elegans] sp|P34275|IVD_CAEEL Probable isovaleryl-CoA dehydrogenase (IVD) 0.0
blast AAP13781 Cyclin e protein 1, isoform b [Caenorhabditis elegans] ref|NP_001021028.1| CYclin E family member (cye-1) [Caenorhabditis elegans] 0.0
blast AAK68235 Cyclin e protein 1, isoform a [Caenorhabditis elegans] ref|NP_001021027.1| CYclin E family member (cye-1) [Caenorhabditis elegans] gb|AAM78547.1| cyclin E [Caenorhabditis elegans] sp|O01501|CCNE_CAEEL G1/S-specific cyclin E gb|AAC63505.1| cyclin E [Caenorhabditis elegans] 0.0
blast CAE71237 Hypothetical protein CBG18107 [Caenorhabditis briggsae] 1.0E-179
Protein Families
Method ID Description E-Value
ec ACDL_HUMAN (P28330) Acyl-CoA dehydrogenase, long-chain specific, mitochondrial precursor (EC 1.3.99.13) (LCAD) 1.0E-130
ec ACDL_HUMAN (P28330) Acyl-CoA dehydrogenase, long-chain specific, mitochondrial precursor (EC 1.3.99.13) (LCAD) 1.0E-131
Protein Domains
Database ID Description E-Value
Pfam IPR006090 EMBL-EBI Acyl-CoA dehydrogenase, C-terminal 7.0E-55
Pfam IPR006091 EMBL-EBI Acyl-CoA dehydrogenase, central domain 4.3E-58
Pfam IPR006092 EMBL-EBI Acyl-CoA dehydrogenase, N-terminal 1.4E-9
Pfam IPR006090 EMBL-EBI Acyl-CoA dehydrogenase, C-terminal 7.0E-55
Pfam IPR006091 EMBL-EBI Acyl-CoA dehydrogenase, central domain 4.3E-58
Pfam IPR006092 EMBL-EBI Acyl-CoA dehydrogenase, N-terminal 1.4E-9
Pfam IPR006671 EMBL-EBI Cyclin, N-terminal domain 8.9E-13
Sequence
Target Sequence 
>C. ELEGANS:190478_AT
gttcatagatcaactccactggataagttgggaatgagaagttcggatactgttcagtta
ttttttgaagatgttcgcgtcccttcatcttacataattggagaagaaggtcgtggattt
ggatatcaaatgaaacaattcaatgatgaacgtcttgtaactgttgctgttggccttctt
ccacttcaaaaatgtattgatgagacaattgaatatgcaagggatcgattgcttttcgga
aagactcttcttgatcaacaatacattcaattccaattggctgagttggaagcagagctc
gaggcaactcgtgcactgttgtatcgaactgttctggcacgaagccgtggagatgatgtg
agcatgttgactgcaatggcaaaattgaagattggaagattggctagagctattactgat
cagtgtttgcaggtgtggggaggtgcaggatatttgaatgaaaatggaatttcgagagct
ttccgagatttccgtcttttctcgatcggagccggttgcgatgaggtcatg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTTCATAGATCAACTCCACTGGATA 88 445 760 Antisense
TTTTTTGAAGATGTTCGCGTCCCTT 478 675 820 Antisense
GCGTCCCTTCATCTTACATAATTGG 685 287 836 Antisense
CTTGTAACTGTTGCTGTTGGCCTTC 630 217 913 Antisense
AGAGCTCGAGGCAACTCGTGCACTG 653 69 1053 Antisense
CGTGCACTGTTGTATCGAACTGTTC 336 245 1069 Antisense
GAACTGTTCTGGCACGAAGCCGTGG 77 349 1085 Antisense
GGCTAGAGCTATTACTGATCAGTGT 678 537 1161 Antisense
TCGAGAGCTTTCCGAGATTTCCGTC 37 603 1231 Antisense
AGATTTCCGTCTTTTCTCGATCGGA 252 65 1245 Antisense
CGGAGCCGGTTGCGATGAGGTCATG 665 239 1266 Antisense
Sequence Source Affymetrix Proprietary Database