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[190475_at] serine/threonine kinase

Description W07G4.3 /REP_DB=WormBase Gene ID /WP=CE14688 /TR=Q23215 /GB=CAB01444.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster 6grp_total > 56      4grp_total > 35      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 57
1 2 3 4 range
A 150.7
(3)
A 		135.9
(-2.7)
A 		135.2
(-3)
A 		138.8
(-1.6)
A 		16
B 119
(-3)
A 		157.1
(3)
A 		149.6
(1.8)
A 		135.6
(-0.4)
A 		38
C 169.1
(1.8)
A 		175.5
(3)
A 		142.5
(-3)
A 		167.6
(1.6)
A 		33
avr 146.3
(-1.3) 		156.2
(3) 		142.4
(-3) 		147.3
(-0.9) 		14

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 133
1 2 3 4 5 6 range
A 154.6
(1.6)
A 		104.2
(-1)
A 		82.1
(-2.1)
A 		64.8
(-3)
A 		101.5
(-1.1)
A 		182.6
(3)
A 		118
B 117.8
(0.3)
A 		126.2
(0.8)
A 		119.1
(0.4)
A 		129
(0.9)
A 		51.2
(-3)
A 		170.6
(3)
P 		119
C 90.1
(-2)
A 		125.3
(-0.1)
A 		138.1
(0.5)
A 		100.4
(-1.5)
A 		71.8
(-3)
A 		184.1
(3)
M 		112
avr 120.8
(-0.4) 		118.6
(-0.5) 		113.1
(-0.8) 		98.1
(-1.7) 		74.8
(-3) 		179.1
(3) 		104
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 36
1 2 3 4 range
A 54.9
(3)
A 		29.5
(-1.4)
A 		35.3
(-0.4)
A 		20.3
(-3)
A 		35
B 37.9
(2.5)
A 		38.8
(3)
A 		34.7
(0.5)
A 		28.9
(-3)
A 		10
C 56
(3)
A 		50.4
(1.8)
A 		49.7
(1.6)
A 		28.3
(-3)
A 		28
avr 49.6
(3) 		39.6
(0.5) 		39.9
(0.6) 		25.8
(-3) 		24

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 47
1 2 3 4 5 6 range
A 28.5
(-0.4)
A 		37.1
(1.4)
A 		17.9
(-2.7)
A 		16.4
(-3)
A 		30.6
(0)
A 		44.5
(3)
A 		28
B 41
(-0.2)
A 		42
(-0)
A 		28.9
(-1.9)
A 		34.2
(-1.1)
A 		20.8
(-3)
A 		63.6
(3)
P 		43
C 33.4
(-1.1)
A 		38.2
(-0.4)
A 		35.1
(-0.8)
A 		20.2
(-3)
A 		23.2
(-2.6)
A 		61.6
(3)
M 		41
avr 34.3
(-1.1) 		39.1
(-0.2) 		27.3
(-2.3) 		23.6
(-3) 		24.9
(-2.8) 		56.6
(3) 		33
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190475_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.13453
Sequence Type Exemplar sequence
Representative Public ID W07G4.3 NCBI
Target Description W07G4.3 /REP_DB=WormBase Gene ID /WP=CE14688 /TR=Q23215 /GB=CAB01444.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073858(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073858 NCBI Caenorhabditis elegans W07G4.3 (W07G4.3) mRNA, complete cds. 11/11 None
SNAP00000014598 ENSEMBL cdna:SNAP chromosome:CEL140:V:13041347:13044312:-1 11/11 None
GENEFINDER00000014604 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:13041347:13044312:-1 11/11 None
W07G4.3.1 ENSEMBL cdna:known chromosome:CEL140:V:13039587:13044312:-1 gene:W07G4.3 11/11 None
W07G4.3.2 ENSEMBL cdna:known chromosome:CEL140:V:13039607:13044312:-1 gene:W07G4.3 11/11 None
W07G4.3.3 ENSEMBL cdna:known chromosome:CEL140:V:13041252:13044312:-1 gene:W07G4.3 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:13041346-13044312(-) 100.0 100.0
Public Domain and Genome References
Gene Title serine/threonine kinase
Ensembl W07G4.3
Entrez Gene 179789 Entrez gene
SwissProt Q23215 EMBL-EBI
WormBase CE14688 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:12229_AT HEAT repeat-containing protein at
ATH1-121501:266053_AT HEAT repeat-containing protein at
CANINE_2:CFAAFFX.20959.1.S1_AT similar to SCY1-like 1 cfa
CANINE_2:CFAAFFX.20966.1.S1_S_AT similar to SCY1-like 1 cfa
CANINE_2:CFAAFFX.20970.1.S1_AT similar to SCY1-like 1 cfa
DROSOPHILA_2:1623549_AT dm
DROSGENOME1:150841_AT dm
HG-U133_PLUS_2:223033_S_AT SCY1-like 1 (S. cerevisiae) hs
HG-U133B:223033_S_AT SCY1-like 1 (S. cerevisiae) hs
HU35KSUBA:AA248169_AT SCY1-like 1 (S. cerevisiae) hs
HU35KSUBA:AA263056_AT SCY1-like 1 (S. cerevisiae) hs
U133_X3P:G10444416_3P_A_AT SCY1-like 1 (S. cerevisiae) hs
HG-U95C:48806_AT SCY1-like 1 (S. cerevisiae) hs
HG-U95D:74750_R_AT SCY1-like 1 (S. cerevisiae) hs
HG-U95E:78139_AT SCY1-like 1 (S. cerevisiae) hs
HG-U133_PLUS_2:229601_AT SCY1-like 1 (S. cerevisiae) hs
HG-U133B:229601_AT SCY1-like 1 (S. cerevisiae) hs
HU35KSUBA:AA402801_R_AT SCY1-like 1 (S. cerevisiae) hs
U133_X3P:HS.238839.2.A1_3P_AT SCY1-like 1 (S. cerevisiae) hs
MOE430A:1451051_A_AT SCY1-like 1 (S. cerevisiae) mm
MOUSE430A_2:1451051_A_AT SCY1-like 1 (S. cerevisiae) mm
MOUSE430_2:1451051_A_AT SCY1-like 1 (S. cerevisiae) mm
MOE430A:1430354_X_AT SCY1-like 1 (S. cerevisiae) mm
MOUSE430A_2:1430354_X_AT SCY1-like 1 (S. cerevisiae) mm
MOUSE430_2:1430354_X_AT SCY1-like 1 (S. cerevisiae) mm
MOE430A:1436804_S_AT SCY1-like 1 (S. cerevisiae) mm
MOUSE430A_2:1436804_S_AT SCY1-like 1 (S. cerevisiae) mm
MOUSE430_2:1436804_S_AT SCY1-like 1 (S. cerevisiae) mm
MU19KSUBB:TC31581_AT SCY1-like 1 (S. cerevisiae), mRNA (cDNA clone MGC:18927 IMAGE:3672524) mm
MU19KSUBC:TC35032_AT SCY1-like 1 (S. cerevisiae), mRNA (cDNA clone MGC:18927 IMAGE:3672524) mm
RG-U34C:RC_AI180441_AT SCY1-like 1 (S. cerevisiae) (predicted) rn
RG-U34C:RC_AI234887_AT SCY1-like 1 (S. cerevisiae) (predicted) rn
RAE230A:1399024_AT SCY1-like 1 (S. cerevisiae) (predicted) rn
RAT230_2:1399024_AT SCY1-like 1 (S. cerevisiae) (predicted) rn
RAE230B:1382635_AT SCY1-like 1 (S. cerevisiae) (predicted) rn
RAT230_2:1382635_AT SCY1-like 1 (S. cerevisiae) (predicted) rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB01444 Hypothetical protein W07G4.3 [Caenorhabditis elegans] ref|NP_506259.1| W07G4.3 [Caenorhabditis elegans] 0.0
blast CAE64675 Hypothetical protein CBG09451 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 1.8E-7
Sequence
Target Sequence 
>C. ELEGANS:190475_AT
gggatactccaatagcaactgccacatcatctcccattcctggagtcaaaaagtcatcat
ctagttcgtctgcagccgcgaagaagccaacaattggacgattaaacttaggatcgaatc
tggcaggatcatctgctcagaaacaaaccaaaaaagctattgatgacaatattgatgcac
ttctcggaatatcagcacctccagctgcgggatcttcagtcaagccgaattcgctgaatg
ctctcatgaacaattcttcctcttctacaaatactggatggggattcgatgatcctttac
caacaactaataattcatcagctaacaaaggatgggacgatgatggatggggtgataaca
gtatgtcaagcaatgtgcttcagccaactgcagtactccaaccaacgaaaatgaaggatg
ataaagatgctcgtcgagccgagatgcagg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGGATACTCCAATAGCAACTGCCAC 652 495 1919 Antisense
ATCATCTCCCATTCCTGGAGTCAAA 32 31 1944 Antisense
AGTTCGTCTGCAGCCGCGAAGAAGC 125 65 1981 Antisense
GAATCTGGCAGGATCATCTGCTCAG 506 329 2034 Antisense
GCACTTCTCGGAATATCAGCACCTC 679 315 2095 Antisense
GCTGCGGGATCTTCAGTCAAGCCGA 345 297 2122 Antisense
GAATTCGCTGAATGCTCTCATGAAC 400 323 2145 Antisense
TCATGAACAATTCTTCCTCTTCTAC 251 621 2162 Antisense
GATTCGATGATCCTTTACCAACAAC 440 431 2201 Antisense
GCAATGTGCTTCAGCCAACTGCAGT 75 323 2288 Antisense
GATGCTCGTCGAGCCGAGATGCAGG 507 413 2344 Antisense
Sequence Source Affymetrix Proprietary Database