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[190460_s_at] cyclophillin

Description F31C3.1 /REP_DB=WormBase Gene ID /WP=CE17730 /GEN=cyp-5 /TR=O62190 /GB=CAB07192.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=cyclophillin
Cluster 6grp_highest_10_10 > 17      6grp_high1_10_10 > 61      4grp_highest_8_8 > 13      4grp_high_8_8 > 22      6grp_highest_nonorm > 28      6grp_total > 61      4grp_total > 24      6grp_highest_sub > 04      6grp_cgc > 84      6grp_high1_sub > 04      6grp_cgc_sub > 04      6grp_total_sub > Hat      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 13764
1 2 3 4 range
A 8574.7
(-3)
P 		15783.8
(0.2)
P 		15233
(-0.1)
P 		22175
(3)
P 		13600
B 8411.5
(-3)
P 		12888.2
(-0.9)
P 		15359.9
(0.3)
P 		21106.9
(3)
P 		12695
C 8707.4
(-3)
P 		13793
(-0.7)
P 		14039.2
(-0.5)
P 		21695.9
(3)
P 		12989
avr 8564.5
(-3) 		14155
(-0.4) 		14877.4
(-0.1) 		21659.3
(3) 		13095

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 6979
1 2 3 4 5 6 range
A 9851.7
(-2)
P 		9263.9
(-2.7)
P 		12300.3
(1)
P 		13902.5
(3)
P 		10822.7
(-0.8)
P 		9016.1
(-3)
P 		4886
B 9765.8
(-0.9)
P 		9141.6
(-1.5)
P 		13928.6
(3)
P 		11621.4
(0.8)
P 		11066.5
(0.3)
P 		7556.9
(-3)
P 		6372
C 11016.8
(-0.2)
P 		9159.8
(-1.9)
P 		12087.8
(0.8)
P 		14535.5
(3)
P 		11437
(0.2)
P 		7969.2
(-3)
P 		6566
avr 10211.4
(-0.6) 		9188.4
(-1.8) 		12772.2
(2.3) 		13353.1
(3) 		11108.7
(0.4) 		8180.7
(-3) 		5172
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2211
1 2 3 4 range
A 3122.1
(-3)
P 		3426.2
(-0.9)
P 		3982.2
(3)
P 		3246
(-2.1)
P 		860
B 2682.3
(-3)
P 		3183.1
(-1.3)
P 		3559.3
(-0.1)
P 		4497.9
(3)
P 		1816
C 2882.4
(-3)
P 		3965.6
(0.2)
P 		4893.1
(3)
P 		3658.3
(-0.7)
P 		2011
avr 2895.6
(-3) 		3525
(0) 		4144.9
(3) 		3800.7
(1.3) 		1249

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 2680
1 2 3 4 5 6 range
A 1816.1
(-3)
P 		3294.7
(2.2)
P 		2678.7
(0)
P 		3526
(3)
P 		3265.8
(2.1)
P 		2195.1
(-1.7)
P 		1710
B 3398
(-0.9)
P 		3042.9
(-2.2)
P 		3382.3
(-1)
P 		3078.1
(-2.1)
P 		4496.2
(3)
P 		2817.9
(-3)
P 		1678
C 4083.4
(3)
P 		2794.9
(-2.5)
P 		3076.5
(-1.3)
P 		2923.1
(-1.9)
P 		3700.9
(1.4)
P 		2667.8
(-3)
P 		1416
avr 3099.2
(-0.4) 		3044.2
(-0.7) 		3045.8
(-0.7) 		3175.7
(-0.1) 		3821
(3) 		2560.3
(-3) 		1261
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 190460_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.1013
Sequence Type Exemplar sequence
Representative Public ID F31C3.1 NCBI
Target Description F31C3.1 /REP_DB=WormBase Gene ID /WP=CE17730 /GEN=cyp-5 /TR=O62190 /GB=CAB07192.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=cyclophillin
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_061223(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_061223 NCBI Caenorhabditis elegans F31C3.1 (cyclophillin) mRNA, complete cds. 11/11 None
SNAP00000023485 ENSEMBL cdna:SNAP chromosome:CEL140:I:15048727:15049390:-1 11/11 None
GENEFINDER00000023500 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:15048727:15058797:-1 11/11 None
F31C3.1.1 ENSEMBL cdna:known chromosome:CEL140:I:15048535:15049392:-1 gene:F31C3.1 11/11 None
F31C3.1.2 ENSEMBL cdna:known chromosome:CEL140:I:15048545:15049399:-1 gene:F31C3.1 11/11 None
F31C3.1.3 ENSEMBL cdna:known chromosome:CEL140:I:15048592:15049756:-1 gene:F31C3.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:15048657-15049321(-) 100.0 100.0
Public Domain and Genome References
Gene Title cyclophillin
Gene Symbol cyn-5
Ensembl F31C3.1
Entrez Gene 173374 Entrez gene
SwissProt P52013 EMBL-EBI
WormBase CE17730 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:247791_AT peptidyl-prolyl cis-trans isomerase, putative / cyclophilin, putative / rotamase, putative (ROC7) at
CANINE:1588855_AT similar to Peptidyl-prolyl cis-trans isomerase B precursor (PPIase) (Rotamase) (Cyclophilin B) (S-cyclophilin) (SCYLP) (CYP-S1) cfa
CANINE_2:CFA.7275.1.A1_S_AT similar to Peptidyl-prolyl cis-trans isomerase B precursor (PPIase) (Rotamase) (Cyclophilin B) (S-cyclophilin) (SCYLP) (CYP-S1) cfa
CANINE_2:CFA.7275.1.A1_X_AT similar to Peptidyl-prolyl cis-trans isomerase B precursor (PPIase) (Rotamase) (Cyclophilin B) (S-cyclophilin) (SCYLP) (CYP-S1) cfa
CANINE_2:CFAAFFX.26086.1.S1_S_AT similar to Peptidyl-prolyl cis-trans isomerase B precursor (PPIase) (Rotamase) (Cyclophilin B) (S-cyclophilin) (SCYLP) (CYP-S1) cfa
DROSOPHILA_2:1624611_A_AT dm
DROSGENOME1:147691_AT dm
CHICKEN:GGA.3382.1.S1_AT peptidylprolyl isomerase B (cyclophilin B) gga
HG-U133_PLUS_2:200967_AT peptidylprolyl isomerase B (cyclophilin B) hs
HG-U133A:200967_AT peptidylprolyl isomerase B (cyclophilin B) hs
HG-U133A_2:200967_AT peptidylprolyl isomerase B (cyclophilin B) hs
HG-U133_PLUS_2:200968_S_AT peptidylprolyl isomerase B (cyclophilin B) hs
HG-U133A:200968_S_AT peptidylprolyl isomerase B (cyclophilin B) hs
HG-FOCUS:200968_S_AT peptidylprolyl isomerase B (cyclophilin B) hs
HG-U133A_2:200968_S_AT peptidylprolyl isomerase B (cyclophilin B) hs
HU35KSUBD:RC_H96665_S_AT peptidylprolyl isomerase B (cyclophilin B) hs
HU35KSUBD:RC_H15847_S_AT peptidylprolyl isomerase B (cyclophilin B) hs
HUGENEFL:M63573_AT peptidylprolyl isomerase B (cyclophilin B) hs
U133_X3P:G4758949_3P_AT peptidylprolyl isomerase B (cyclophilin B) hs
HG-U95AV2:35823_AT peptidylprolyl isomerase B (cyclophilin B) hs
HG-U95E:80860_AT Peptidylprolyl isomerase B (cyclophilin B) hs
MOUSE430A_2:1437649_X_AT peptidylprolyl isomerase B mm
MOE430A:1437649_X_AT peptidylprolyl isomerase B mm
MOUSE430_2:1437649_X_AT peptidylprolyl isomerase B mm
MU11KSUBA:M60456_S_AT peptidylprolyl isomerase B mm
MG-U74AV2:94915_AT peptidylprolyl isomerase B mm
MOE430A:1450911_AT peptidylprolyl isomerase B mm
MOUSE430A_2:1450911_AT peptidylprolyl isomerase B mm
MOUSE430_2:1450911_AT peptidylprolyl isomerase B mm
MG-U74CV2:136594_AT Peptidylprolyl isomerase B, mRNA (cDNA clone MGC:6241 IMAGE:3483267) mm
MOUSE430_2:1440275_AT Peptidylprolyl isomerase B, mRNA (cDNA clone MGC:6241 IMAGE:3483267) mm
MOE430B:1440275_AT Peptidylprolyl isomerase B, mRNA (cDNA clone MGC:6241 IMAGE:3483267) mm
MU19KSUBB:TC27331_AT Peptidylprolyl isomerase B, mRNA (cDNA clone MGC:6241 IMAGE:3483267) mm
RT-U34:RC_AA818487_S_AT peptidylprolyl isomerase B rn
RG-U34A:RC_AA818487_S_AT peptidylprolyl isomerase B rn
RT-U34:AF071225_AT peptidylprolyl isomerase B rn
RG-U34A:AF071225_AT peptidylprolyl isomerase B rn
RAE230A:1369934_AT peptidylprolyl isomerase B rn
RAT230_2:1369934_AT peptidylprolyl isomerase B rn
RAE230B:1397502_AT Peptidylprolyl isomerase B rn
RAT230_2:1397502_AT Peptidylprolyl isomerase B rn
YEAST_2:1776093_AT Peptidyl-prolyl cis-trans isomerase (cyclophilin) of the endoplasmic reticulum, catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; transcriptionally induced in response to unfolded proteins in the ER Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6457 protein folding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB07193 Hypothetical protein F31C3.3 [Caenorhabditis elegans] ref|NP_493625.2| F31C3.3 [Caenorhabditis elegans] 0.0
blast CAE72553 Hypothetical protein CBG19737 [Caenorhabditis briggsae] 0.0
blast EAA11765 ENSANGP00000007087 [Anopheles gambiae str. PEST] ref|XP_315477.2| ENSANGP00000007087 [Anopheles gambiae str. PEST] 0.0
blast CAB07192 Hypothetical protein F31C3.1 [Caenorhabditis elegans] ref|NP_493624.1| F31C3.1 [Caenorhabditis elegans] sp|P52013|CYP5_CAEEL Peptidyl-prolyl cis-trans isomerase 5 precursor (PPIase) (Rotamase) (Cyclophilin-5) 2.0E-96
blast AAC47126 cyclophilin isoform 2.0E-95
Protein Domains
Database ID Description E-Value
Pfam IPR002130 EMBL-EBI Peptidyl-prolyl cis-trans isomerase, cyclophilin type 1.6E-106
Pfam IPR002130 EMBL-EBI Peptidyl-prolyl cis-trans isomerase, cyclophilin type 1.6E-106
Trans Membrane
ID Number Of Domains Domain Boundaries
GENEFINDER00000023500 1 7-29
Sequence
Target Sequence 
>C. ELEGANS:190460_S_AT
tgaagtcgcttcttgttgtggcggccgtgctcgctgtcggagctcttgctcagggagacg
atgccaaaggaccaaaggtcactgacaaggtctactttgacatggaaattggaggaaaac
caatcggacgtatcgtcatcggacttttcggaaaaaccgtcccaaagaccgccaccaact
tcattgagctcgccaagaagccaaagggagaaggatatccaggaagcaagttccaccgag
tcatcgcagacttcatgattcaaggaggagatttcacccgtggagatggaaccggaggac
gctctatctacggagagaagttcgccgacgagaacttcaagctgaagcactacggagccg
gatggttgtcgatggccaacgctggagctgataccaatggatcccaattcttcatcacca
cagtcaagaccccatggctcgatggacgccacgtcgttttcggaaagatcctcgaaggaa
tggatgtggtccgcaagatcgaacag

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TGAAGTCGCTTCTTGTTGTGGCGGC 377 573 14 Antisense
GGAGCTCTTGCTCAGGGAGACGATG 447 521 52 Antisense
AATCGGACGTATCGTCATCGGACTT 128 167 135 Antisense
CCAACTTCATTGAGCTCGCCAAGAA 99 275 188 Antisense
CCACCGAGTCATCGCAGACTTCATG 140 275 246 Antisense
GATTTCACCCGTGGAGATGGAACCG 526 427 283 Antisense
ACCGGAGGACGCTCTATCTACGGAG 231 87 304 Antisense
AGCTGAAGCACTACGGAGCCGGATG 20 81 353 Antisense
GAGCCGGATGGTTGTCGATGGCCAA 383 383 368 Antisense
GATACCAATGGATCCCAATTCTTCA 548 423 403 Antisense
GGATGTGGTCCGCAAGATCGAACAG 122 515 495 Antisense
Sequence Source Affymetrix Proprietary Database