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[190457_s_at] tyrosine-protein kinase

Description F54F7.5 /REP_DB=WormBase Gene ID /WP=CE28237 /TR=Q20792 /GB=CAA91758.2 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=tyrosine-protein kinase
Cluster 6grp_total > 78      4grp_total > 44      6grp_cgc > 49      6grp_cgc_sub > Da      6grp_total_sub > Increase      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 26
1 2 3 4 range
A 4.8
(3)
A 		3.4
(-3)
A 		4.3
(0.9)
A 		3.7
(-1.7)
A 		1
B 2
(-2.8)
A 		3.4
(-1.6)
A 		1.8
(-3)
A 		8.5
(3)
A 		7
C 16
(0.2)
A 		27.8
(3)
A 		12.1
(-0.7)
A 		2.3
(-3)
A 		26
avr 7.6
(-0.5) 		11.5
(3) 		6.1
(-1.8) 		4.8
(-3) 		7

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 33
1 2 3 4 5 6 range
A 2.3
(-3)
A 		5.5
(-2.4)
A 		17.4
(-0.1)
A 		8
(-1.9)
A 		8.3
(-1.9)
A 		33.8
(3)
A 		32
B 1
(-3)
A 		17.4
(0.7)
A 		1.8
(-2.8)
A 		4.5
(-2.2)
A 		21.8
(1.7)
A 		27.8
(3)
A 		27
C 17.1
(3)
A 		1.4
(-3)
A 		2.1
(-2.7)
A 		5.5
(-1.4)
A 		9.6
(0.1)
A 		10
(0.3)
A 		16
avr 6.8
(-2.7) 		8.1
(-2.3) 		7.1
(-2.6) 		6
(-3) 		13.2
(-0.6) 		23.9
(3) 		18
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 8
1 2 3 4 range
A 1.8
(3)
A 		0.7
(-2.1)
A 		1.1
(-0.2)
A 		0.5
(-3)
A 		1
B 0.6
(-2.1)
A 		0.8
(-1.3)
A 		0.4
(-3)
A 		1.8
(3)
A 		1
C 5.3
(0.9)
A 		8
(3)
A 		4.2
(0)
A 		0.4
(-3)
A 		8
avr 2.6
(1.4) 		3.2
(3) 		1.9
(-0.4) 		0.9
(-3) 		2

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 10
1 2 3 4 5 6 range
A 0.4
(-3)
A 		2
(-1.8)
A 		3.8
(-0.4)
A 		2
(-1.8)
A 		2.5
(-1.4)
A 		8.2
(3)
A 		8
B 0.3
(-3)
A 		5.8
(0.3)
A 		0.4
(-2.9)
A 		1.2
(-2.5)
A 		8.8
(2)
A 		10.4
(3)
A 		10
C 6.3
(3)
A 		0.4
(-3)
A 		0.5
(-2.9)
A 		1.1
(-2.3)
A 		3.1
(-0.3)
A 		3.3
(-0.1)
A 		6
avr 2.3
(-2.1) 		2.7
(-1.7) 		1.6
(-2.8) 		1.4
(-3) 		4.8
(0.5) 		7.3
(3) 		6
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 190457_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.16227
Sequence Type Exemplar sequence
Representative Public ID F54F7.5 NCBI
Target Description F54F7.5 /REP_DB=WormBase Gene ID /WP=CE28237 /TR=Q20792 /GB=CAA91758.2 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=tyrosine-protein kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_171780(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_171780 NCBI Caenorhabditis elegans Maternal Effect Sterile family member (mes-1) (mes-1) mRNA, complete cds. 11/11 A 
GENEFINDER00000009572 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:11856127:11861815:1 11/11 None
SNAP00000009560 ENSEMBL cdna:SNAP chromosome:CEL140:X:11857422:11861815:1 11/11 None
F54F7.5 ENSEMBL cdna:known chromosome:CEL140:X:11857415:11862294:1 gene:F54F7.5 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:11857421-11861815(+) 100.0 100.0
Public Domain and Genome References
Gene Title tyrosine-protein kinase
Gene Symbol mes-1
Ensembl F54F7.5
Entrez Gene 181362 Entrez gene
SwissProt Q20792 EMBL-EBI
WormBase CE28237 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5887 integral to plasma membrane inferred from direct assay QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from sequence similarity QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA91758 Hypothetical protein F54F7.5 [Caenorhabditis elegans] ref|NP_741906.1| Maternal Effect Sterile family member (mes-1) [Caenorhabditis elegans] gb|AAF13716.1| MES-1 [Caenorhabditis elegans] 0.0
blast CAE69868 Hypothetical protein CBG16200 [Caenorhabditis briggsae] 0.0
blast CAA91529 Hypothetical protein B0198.3 [Caenorhabditis elegans] ref|NP_510015.2| B0198.3 [Caenorhabditis elegans] 0.0
Protein Domains
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_741906.1 1 469-491
F54F7.5 1 469-491
GENEFINDER00000009572 1 557-579
SNAP00000009560 1 469-491
Sequence
Target Sequence 
>C. ELEGANS:190457_S_AT
tagccactgaccatgattcttttgccagtcagcaggacatgaattctactcaacatcctt
ttgataaactctctactgaagctgacgagaataactctaagaaggtgaagatccaagaaa
tcactgatagcttgtccattcggttctgccagttcgctgagcaagtgtcttcagcactag
aacatcttcacagtgcaggatctgttcatacaagagtgacaactctcaacatttatcttc
ttcacaattactcggatccatttgacatgcttcccgatcaggttgtcaaattgggcaatt
tcgggtttgcagttcaaaactctgaggacgttgtacttgacgacaatctccagccaccag
aagtaattaaaggagaaaaatatgaagcgagaggggatatttggcagtttggactgtgtc
tagccgagatgtgcagcttaggagatcttgagcagtcggaagttggcactttgaagtccg
gacatgatacattcaagaatttaccatccacccaagttcttcgtgacgcagcaaaacggt
gtctcagtgcacgcac

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TAGCCACTGACCATGATTCTTTTGC 607 649 2330 Antisense
GATAAACTCTCTACTGAAGCTGACG 402 421 2392 Antisense
CACTGATAGCTTGTCCATTCGGTTC 123 199 2451 Antisense
GCCAGTTCGCTGAGCAAGTGTCTTC 145 281 2477 Antisense
TGACAACTCTCAACATTTATCTTCT 625 571 2546 Antisense
CTTCTTCACAATTACTCGGATCCAT 454 221 2566 Antisense
CATGCTTCCCGATCAGGTTGTCAAA 437 209 2595 Antisense
TGTACTTGACGACAATCTCCAGCCA 691 559 2661 Antisense
GCAGTTTGGACTGTGTCTAGCCGAG 187 311 2733 Antisense
AGAATTTACCATCCACCCAAGTTCT 218 65 2825 Antisense
CAAAACGGTGTCTCAGTGCACGCAC 176 191 2861 Antisense
Sequence Source Affymetrix Proprietary Database