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[190456_at] serine/threonine kinase

Description E02H4.6 /REP_DB=WormBase Gene ID /WP=CE05552 /TR=Q19043 /GB=CAA94215.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster 6grp_total > 78      4grp_total > 09      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 11
1 2 3 4 range
A 2.4
(-2.9)
A 		2.3
(-3)
A 		4.6
(-0.5)
A 		7.8
(3)
A 		6
B 5.5
(-0.6)
A 		6.1
(0.8)
A 		7.1
(3)
A 		4.4
(-3)
A 		3
C 1.8
(-3)
A 		3.1
(-2.3)
A 		1.9
(-2.9)
A 		12.5
(3)
A 		11
avr 3.2
(-3) 		3.8
(-2.3) 		4.5
(-1.4) 		8.2
(3) 		5

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 167
1 2 3 4 5 6 range
A 15.4
(-2.4)
A 		1.8
(-3)
A 		2.2
(-3)
A 		4.3
(-2.9)
A 		59.5
(-0.5)
A 		137.8
(3)
A 		136
B 2.9
(-3)
A 		3.7
(-2.9)
A 		3.9
(-2.9)
A 		2
(-3)
A 		40
(-1.6)
A 		168.9
(3)
A 		167
C 2.3
(-3)
A 		9.4
(-2.6)
A 		1.7
(-3)
A 		2.8
(-2.9)
A 		41.9
(-0.9)
A 		114
(3)
A 		112
avr 6.9
(-2.8) 		5
(-2.9) 		2.6
(-3) 		3
(-3) 		47.1
(-1.1) 		140.2
(3) 		138
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2
1 2 3 4 range
A 0.9
(0.4)
A 		0.5
(-3)
A 		1.2
(3)
A 		1.1
(2.1)
A 		1
B 1.8
(3)
A 		1.5
(1)
A 		1.7
(2.3)
A 		0.9
(-3)
A 		1
C 0.6
(-3)
A 		0.9
(-1.8)
A 		0.7
(-2.6)
A 		2.1
(3)
A 		2
avr 1.1
(-1.5) 		1
(-3) 		1.2
(0) 		1.4
(3) 		0

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 63
1 2 3 4 5 6 range
A 2.8
(-2.6)
A 		0.6
(-3)
A 		0.5
(-3)
A 		1.1
(-2.9)
A 		18
(0.2)
A 		33.5
(3)
A 		33
B 1
(-3)
A 		1.2
(-2.9)
A 		1
(-3)
A 		0.5
(-3)
A 		16.2
(-1.5)
A 		63
(3)
A 		63
C 0.9
(-2.9)
A 		2.9
(-2.6)
A 		0.4
(-3)
A 		0.6
(-3)
A 		13.5
(-0.9)
A 		38.2
(3)
A 		38
avr 1.6
(-2.9) 		1.6
(-2.9) 		0.6
(-3) 		0.7
(-3) 		15.9
(-0.9) 		44.9
(3) 		44
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190456_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.17858
Sequence Type Exemplar sequence
Representative Public ID E02H4.6 NCBI
Target Description E02H4.6 /REP_DB=WormBase Gene ID /WP=CE05552 /TR=Q19043 /GB=CAA94215.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_077976(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_077976 NCBI Caenorhabditis elegans E02H4.6 (E02H4.6) mRNA, complete cds. 11/11 None
E02H4.6 ENSEMBL cdna:known chromosome:CEL140:X:14250641:14252056:-1 gene:E02H4.6 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
GENEFINDER00000016462 6/11 Cross Hyb Matching Probes None
SNAP00000016448 6/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:14250640-14252056(-) 100.0 100.0
Public Domain and Genome References
Gene Title serine/threonine kinase
Ensembl E02H4.6
Entrez Gene 183997 Entrez gene
SwissProt Q19043 EMBL-EBI
WormBase CE05552 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA94215 Hypothetical protein E02H4.6 [Caenorhabditis elegans] emb|CAA91980.1| Hypothetical protein E02H4.6 [Caenorhabditis elegans] ref|NP_510377.1| E02H4.6 [Caenorhabditis elegans] 1.0E-171
blast CAA94212 Hypothetical protein K04C1.5 [Caenorhabditis elegans] ref|NP_510376.1| K04C1.5 [Caenorhabditis elegans] 2.0E-53
blast AAB00613 Hypothetical protein F39F10.3 [Caenorhabditis elegans] ref|NP_510730.1| F39F10.3 [Caenorhabditis elegans] 2.0E-14
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 1.0E-8
Sequence
Target Sequence 
>C. ELEGANS:190456_AT
gtacctggcaactctggagcagttcagaacgcgatgcgacgatagaagaatttccgattt
gaatatcatcaaaattgctgttcgcctcgtgaacgtcttggaggcaattcaccaaaaagg
tgtcattcatcgtgacctcaaaacgaccaatgtgatgattcgctcaagggggcagagtga
agtcaacttggtgctcattgactatggcctctcaactttcaacggaactccgccccgcgc
ccttgcgccagacgcaaaatctcctgaaatcatgtttcgcggacacacacacgtttcgcc
agcactcgaagaaggtctcaaagctgatgctgtcgatgatttgcaaatgttggcaatcat
gctcatctggtgctcggcctaccatccgtttggtccaatcgggcaagagtcttctcgaaa
gaaggcggagtttatcacaaatccggtcaaatacgtgaaaggccgtccattcttgcgacc
attgatgacagcgattatggcacaacctcgaggcactcgtcccaactatcaagctatcct
ggatgcagccgctggtccatttccaattgacga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTACCTGGCAACTCTGGAGCAGTTC 50 459 297 Antisense
CAAAATTGCTGTTCGCCTCGTGAAC 350 189 366 Antisense
TTGGTGCTCATTGACTATGGCCTCT 613 707 484 Antisense
CTCTCAACTTTCAACGGAACTCCGC 268 231 505 Antisense
GAAATCATGTTTCGCGGACACACAC 232 363 562 Antisense
TACCATCCGTTTGGTCCAATCGGGC 513 641 676 Antisense
ATACGTGAAAGGCCGTCCATTCTTG 282 23 747 Antisense
GTCCATTCTTGCGACCATTGATGAC 306 477 761 Antisense
GCGATTATGGCACAACCTCGAGGCA 572 289 787 Antisense
TCAAGCTATCCTGGATGCAGCCGCT 102 631 825 Antisense
CCGCTGGTCCATTTCCAATTGACGA 134 263 845 Antisense
Sequence Source Affymetrix Proprietary Database