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[190455_at] tyrosine-protein kinase

Description W01B6.5 /REP_DB=WormBase Gene ID /WP=CE03757 /TR=Q23102 /GB=CAA92623.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=tyrosine-protein kinase
Cluster 6grp_total > 86      4grp_total > 02      6grp_total_sub > Increase      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 54
1 2 3 4 range
A 36.5
(-3)
A 		36.4
(-3)
A 		48.7
(3)
A 		37.9
(-2.3)
A 		12
B 27.7
(-0.9)
A 		10.2
(-3)
A 		11.9
(-2.8)
A 		59.9
(3)
A 		50
C 19.3
(-2.8)
A 		33.8
(-0.9)
A 		17.6
(-3)
A 		64.5
(3)
P 		47
avr 27.8
(-2.6) 		26.8
(-2.9) 		26.1
(-3) 		54.1
(3) 		28

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 88
1 2 3 4 5 6 range
A 24.8
(-2.1)
A 		36.9
(-0.6)
A 		44.6
(0.4)
A 		17.2
(-3)
A 		66.1
(3)
P 		59.6
(2.2)
P 		49
B 38.8
(-0.9)
A 		48.9
(0.2)
M 		20.6
(-3)
A 		73.4
(3)
A 		51.7
(0.5)
P 		60.2
(1.5)
P 		53
C 16.8
(-3)
A 		44.6
(-1.1)
A 		26.7
(-2.3)
A 		78.4
(1.2)
A 		33.1
(-1.9)
A 		104.5
(3)
P 		88
avr 26.8
(-3) 		43.5
(-0.9) 		30.6
(-2.5) 		56.3
(0.7) 		50.3
(-0.1) 		74.8
(3) 		48
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 11
1 2 3 4 range
A 13.3
(3)
A 		7.9
(-1.2)
A 		12.7
(2.5)
A 		5.5
(-3)
A 		8
B 8.8
(0.7)
A 		2.5
(-3)
A 		2.7
(-2.9)
A 		12.8
(3)
A 		10
C 6.4
(-2.6)
A 		9.7
(1.5)
A 		6.1
(-3)
A 		10.9
(3)
P 		5
avr 9.5
(2.6) 		6.7
(-3) 		7.2
(-2) 		9.7
(3) 		3

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 31
1 2 3 4 5 6 range
A 4.6
(-2.9)
A 		13.1
(0.4)
A 		9.7
(-0.9)
A 		4.4
(-3)
A 		19.9
(3)
P 		14.5
(0.9)
P 		16
B 13.5
(-0.1)
A 		16.3
(0.9)
M 		5
(-3)
A 		19.4
(2)
A 		21
(2.5)
P 		22.4
(3)
P 		17
C 6.2
(-3)
A 		13.6
(-1.5)
A 		6.8
(-2.9)
A 		15.8
(-1)
A 		10.7
(-2.1)
A 		35
(3)
P 		29
avr 8.1
(-2.7) 		14.3
(-0.5) 		7.2
(-3) 		13.2
(-0.9) 		17.2
(0.6) 		24
(3) 		17
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190455_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.9354
Sequence Type Exemplar sequence
Representative Public ID W01B6.5 NCBI
Target Description W01B6.5 /REP_DB=WormBase Gene ID /WP=CE03757 /TR=Q23102 /GB=CAA92623.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=tyrosine-protein kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069425(9)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069425 NCBI Caenorhabditis elegans W01B6.5 (W01B6.5) mRNA, complete cds. 9/11 None
SNAP00000040430 ENSEMBL cdna:SNAP chromosome:CEL140:IV:10076297:10078621:1 9/11 None
GENEFINDER00000040438 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:10076297:10078621:1 9/11 None
W01B6.5 ENSEMBL cdna:known chromosome:CEL140:IV:10076297:10078621:1 gene:W01B6.5 9/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:10076302-10078627(+) 100.0 100.0
Public Domain and Genome References
Gene Title tyrosine-protein kinase
Ensembl W01B6.5
Entrez Gene 189082 Entrez gene
SwissProt Q23102 EMBL-EBI
WormBase CE35632 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
7242 intracellular signaling cascade inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA92623 Hypothetical protein W01B6.5 [Caenorhabditis elegans] ref|NP_501826.2| W01B6.5 [Caenorhabditis elegans] 0.0
blast CAE60040 Hypothetical protein CBG03551 [Caenorhabditis briggsae] 0.0
blast AAB37822 Hypothetical protein F59A3.8 [Caenorhabditis elegans] ref|NP_491620.2| F59A3.8 [Caenorhabditis elegans] 1.0E-139
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 7.6E-57
Sequence
Target Sequence 
>C. ELEGANS:190455_AT
gctctccgtgagtatctccgtgagaatcaggaaacagtgacacttgctgaaaagttattt
tttgttgttggttcatctcgtggtgtacaatatcttcactcacaaaaaacaattcacaga
gatttggcagttcggaatattcttctcatccacaaacgtcatgatcctgccattaccaat
tcaacagtctcaatgggtacttttttgtttcagccaaaaatttctgattttggattggca
aaaatcagtgaacgatacgagatgaaggaacagtgcaagattcctgtacgatacctggca
cctgagactctcgaaagcttcatcttcacaacaaaaactgatgttttctcatttggatgt
gtcatttgggagatctatgagaacgggaatcaaccacatgatggaaagaatgcacagacg
attcgaaacttgacgaagaagaatcagttcttgaaattaaccaactcggcgccttccgaa
ctccgaaaattgatcgaggaacgagttttcacgtctgatcctgaaaatcgatgttccatg
acaacaattgtgcagtgcgccgaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GCTCTCCGTGAGTATCTCCGTGAGA 636 299 1078 Antisense
TTTTGTTGTTGGTTCATCTCGTGGT 638 675 1137 Antisense
GTGGTGTACAATATCTTCACTCACA 470 489 1157 Antisense
ATTCTTCTCATCCACAAACGTCATG 560 11 1216 Antisense
ATGATCCTGCCATTACCAATTCAAC 320 47 1238 Antisense
AAGATTCCTGTACGATACCTGGCAC 516 155 1354 Antisense
GGCACCTGAGACTCTCGAAAGCTTC 64 537 1374 Antisense
TTGAAATTAACCAACTCGGCGCCTT 400 685 1528 Antisense
CGCCTTCCGAACTCCGAAAATTGAT 130 255 1547 Antisense
GAACGAGTTTTCACGTCTGATCCTG 602 347 1576 Antisense
GACAACAATTGTGCAGTGCGCCGAA 384 365 1617 Antisense
Sequence Source Affymetrix Proprietary Database