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[190439_s_at] Caveolin

Description C56A3.7 /REP_DB=WormBase Gene ID /WP=CE15738 /GEN=cav-2 /TR=SW:Q18879 /GB=CAB01139.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=Caveolin
Cluster 6grp_highest_10_10 > 01      6grp_high1_10_10 > 10      4grp_highest_8_8 > 51      4grp_high_8_8 > 32      6grp_highest_nonorm > 41      6grp_total > 13      4grp_total > 47      6grp_cgc > 50      6grp_total_sub > Decrease      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1323
1 2 3 4 range
A 1258.1
(3)
P 		287.7
(-3)
P 		303.1
(-2.9)
P 		324.2
(-2.8)
P 		970
B 1580.8
(3)
P 		300.1
(-2.8)
P 		268.7
(-3)
P 		261.9
(-3)
P 		1319
C 1192.8
(3)
P 		258
(-3)
P 		372.6
(-2.3)
P 		303.2
(-2.7)
P 		935
avr 1343.9
(3) 		281.9
(-3) 		314.8
(-2.8) 		296.4
(-2.9) 		1062

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 626
1 2 3 4 5 6 range
A 913.4
(2.5)
P 		955.9
(3)
P 		606.1
(-1)
P 		776.8
(0.9)
P 		667.7
(-0.3)
P 		436.2
(-3)
P 		520
B 708.1
(1.8)
P 		647.9
(0.7)
P 		585.3
(-0.4)
P 		778.3
(3)
P 		661.7
(1)
P 		435.5
(-3)
P 		343
C 844.1
(0.6)
P 		875.2
(0.9)
P 		1061.8
(3)
P 		885
(1)
P 		586.1
(-2.3)
P 		520.4
(-3)
P 		541
avr 821.9
(2.9) 		826.3
(3) 		751.1
(1.8) 		813.4
(2.8) 		638.5
(-0.1) 		464
(-3) 		362
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 457
1 2 3 4 range
A 458.1
(3)
P 		62.4
(-2.8)
P 		79.2
(-2.5)
P 		47.5
(-3)
P 		411
B 504.1
(3)
P 		74.1
(-2.8)
P 		62.3
(-2.9)
P 		55.8
(-3)
P 		448
C 394.8
(3)
P 		74.2
(-2.6)
P 		129.9
(-1.6)
P 		51.1
(-3)
P 		344
avr 452.3
(3) 		70.2
(-2.7) 		90.5
(-2.4) 		51.5
(-3) 		401

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 234
1 2 3 4 5 6 range
A 168.4
(-1.4)
P 		340
(3)
P 		132
(-2.3)
P 		197
(-0.7)
P 		201.5
(-0.6)
P 		106.2
(-3)
P 		234
B 246.4
(1.9)
P 		215.7
(0.5)
P 		142.1
(-3)
P 		206.2
(0)
P 		268.9
(3)
P 		162.4
(-2)
P 		127
C 312.9
(3)
P 		267.1
(1)
P 		270.2
(1.2)
P 		178
(-2.8)
P 		189.7
(-2.3)
P 		174.2
(-3)
P 		139
avr 242.6
(1.5) 		274.3
(3) 		181.4
(-1.4) 		193.7
(-0.8) 		220
(0.4) 		147.6
(-3) 		127
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 190439_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.14492
Sequence Type Exemplar sequence
Representative Public ID C56A3.7 NCBI
Target Description C56A3.7 /REP_DB=WormBase Gene ID /WP=CE15738 /GEN=cav-2 /TR=SW:Q18879 /GB=CAB01139.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=Caveolin
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073956(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073956 NCBI Caenorhabditis elegans C56A3.7 (Caveolin) mRNA, complete cds. 11/11 None
SNAP00000001398 ENSEMBL cdna:SNAP chromosome:CEL140:V:13559752:13564550:1 11/11 None
GENEFINDER00000001406 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:13559752:13564550:1 10/11 None
C56A3.7 ENSEMBL cdna:known chromosome:CEL140:V:13559752:13562393:1 gene:C56A3.7 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:13559751-13562393(+) 95.64 100.0
Public Domain and Genome References
Gene Title Caveolin
Gene Symbol cav-2
Ensembl C56A3.7
Entrez Gene 179838 Entrez gene
SwissProt Q18879 EMBL-EBI
WormBase CE15738 Wormbase
Functional Annotations
Gene Ontology
GO Cellular Component (view graph)
ID Description Evidence Links
16599 caveolar membrane inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB01138 Hypothetical protein C56A3.8 [Caenorhabditis elegans] ref|NP_506358.1| C56A3.8 [Caenorhabditis elegans] 0.0
blast CAE62562 Hypothetical protein CBG06673 [Caenorhabditis briggsae] 0.0
blast CAB01139 Hypothetical protein C56A3.7 [Caenorhabditis elegans] ref|NP_506357.3| C56A3.7 [Caenorhabditis elegans] 1.0E-154
blast Q18879 Caveolin-2 gb|AAB48299.1| caveolin-2 [Caenorhabditis elegans] 1.0E-153
blast CAB01139 Hypothetical protein C56A3.7 [Caenorhabditis elegans] ref|NP_506357.3| C56A3.7 [Caenorhabditis elegans] 1.0E-148
blast CAB01139 Hypothetical protein C56A3.7 [Caenorhabditis elegans] ref|NP_506357.3| C56A3.7 [Caenorhabditis elegans] 1.0E-138
Protein Domains
Database ID Description E-Value
Pfam IPR001612 EMBL-EBI Caveolin 2.8E-115
Pfam IPR000403 EMBL-EBI Phosphatidylinositol 3- and 4-kinase 3.8E-88
Pfam IPR000403 EMBL-EBI Phosphatidylinositol 3- and 4-kinase 3.8E-88
Pfam IPR001612 EMBL-EBI Caveolin 2.8E-115
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_506357.3 2 262-284,299-321
C56A3.7 2 262-284,299-321
SNAP00000001398 2 265-287,294-316
GENEFINDER00000001406 3 164-186,290-312,319-341
Sequence
Target Sequence 
>C. ELEGANS:190439_S_AT
aaaagactacgcaccgtcaattccactcccagaacatcctgctcaacaatctgcaccacc
cacgcaacaatctcgcccacaaactacctcacataagccaccaaatcctgaaatggaatt
tgacattggagttaaaaatattgctcctgtacttattcataagatgaacatggatgatcg
agacccaaaagattctgcacagtatttgaatacatcgttcttcgaagttttcaacgagcc
aagtgagcagtatcatagtattgcatgtgtctggacattgtctttcaaaatttttgaaat
agttcgaatctacagttacaagattcttactcttattttcggactcatcattgcattttt
gggcggaatcttattcgctttatttgcatttttgaacatttggatcttccggccaatcct
cattctgacccgaatggcttttgcacagattgtcttgatttggccaatgttcttaattta
catagttcgtccattcttctactcagttggagcaatcttttcgactgcacgactacatac
atctc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAAAGACTACGCACCGTCAATTCCA 535 131 474 Antisense
GAACATCCTGCTCAACAATCTGCAC 375 351 505 Antisense
ATATTGCTCCTGTACTTATTCATAA 432 19 611 Antisense
GATTCTTACTCTTATTTTCGGACTC 87 431 795 Antisense
TCGGACTCATCATTGCATTTTTGGG 229 603 812 Antisense
GGAATCTTATTCGCTTTATTTGCAT 355 533 838 Antisense
AACATTTGGATCTTCCGGCCAATCC 137 139 868 Antisense
TTCTGACCCGAATGGCTTTTGCACA 434 693 896 Antisense
TACATAGTTCGTCCATTCTTCTACT 312 643 952 Antisense
GTTGGAGCAATCTTTTCGACTGCAC 169 437 979 Antisense
TCGACTGCACGACTACATACATCTC 102 601 994 Antisense
Sequence Source Affymetrix Proprietary Database