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[190382_s_at] TPR Domain (2 domains)

Description T12D8.8 /REP_DB=WormBase Gene ID /WP=CE16405 /TR=O45786 /GB=CAB05818.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=TPR Domain (2 domains)
Cluster 6grp_highest_10_10 > 83      6grp_high1_10_10 > 47      4grp_highest_8_8 > 09      4grp_high_8_8 > 53      6grp_highest_nonorm > 77      6grp_total > 48      4grp_total > 58      6grp_highest_sub > Cu      6grp_high1_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 528
1 2 3 4 range
A 1733
(-3)
P 		2183.7
(3)
P 		1982.4
(0.3)
P 		1750.7
(-2.8)
P 		451
B 1911.7
(3)
P 		1761.8
(-1.4)
P 		1858.8
(1.5)
P 		1705.7
(-3)
P 		206
C 1805.6
(-0.5)
P 		1865.2
(0.5)
P 		2017.4
(3)
P 		1655.4
(-3)
P 		362
avr 1816.8
(-0.3) 		1936.9
(2.6) 		1952.9
(3) 		1703.9
(-3) 		249

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 822
1 2 3 4 5 6 range
A 1396.8
(1.4)
P 		1404.8
(1.5)
P 		1340.5
(0.7)
P 		1271.1
(-0.3)
P 		1061.5
(-3)
P 		1520
(3)
P 		459
B 1191.2
(-1.9)
P 		1382.4
(0.3)
P 		1502.8
(1.7)
P 		1092
(-3)
P 		1278.1
(-0.9)
P 		1614.6
(3)
P 		523
C 1870.7
(3)
P 		1048.9
(-3)
P 		1316.9
(-1)
P 		1153.6
(-2.2)
P 		1487.1
(0.2)
P 		1322.8
(-1)
P 		822
avr 1486.2
(3) 		1278.7
(-1) 		1386.7
(1.1) 		1172.2
(-3) 		1275.6
(-1) 		1485.8
(3) 		314
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 447
1 2 3 4 range
A 631
(3)
P 		474
(0.5)
P 		518.2
(1.2)
P 		256.3
(-3)
P 		375
B 609.6
(3)
P 		435.1
(-1.3)
P 		430.7
(-1.4)
P 		363.5
(-3)
P 		246
C 597.7
(1.5)
P 		536.2
(0.6)
P 		703.1
(3)
P 		279.1
(-3)
P 		424
avr 612.8
(3) 		481.8
(0.5) 		550.7
(1.8) 		299.6
(-3) 		313

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 461
1 2 3 4 5 6 range
A 257.5
(-3)
P 		499.6
(3)
P 		291.9
(-2.1)
P 		322.4
(-1.4)
P 		320.3
(-1.4)
P 		370.1
(-0.2)
P 		242
B 414.5
(-0.6)
P 		460.1
(0.3)
P 		364.9
(-1.5)
P 		289.2
(-3)
P 		519.3
(1.4)
P 		602.1
(3)
P 		313
C 693.4
(3)
P 		320.1
(-1.9)
P 		335.2
(-1.7)
P 		232
(-3)
P 		481.2
(0.2)
P 		442.8
(-0.3)
P 		461
avr 455.1
(2.5) 		426.6
(1.6) 		330.7
(-1.4) 		281.2
(-3) 		440.3
(2) 		471.7
(3) 		191
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 190382_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.7898
Sequence Type Exemplar sequence
Representative Public ID T12D8.8 NCBI
Target Description T12D8.8 /REP_DB=WormBase Gene ID /WP=CE16405 /TR=O45786 /GB=CAB05818.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=TPR Domain (2 domains)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_067410(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_067410 NCBI Caenorhabditis elegans T12D8.8 (T12D8.8) mRNA, complete cds. 11/11 None
SNAP00000008509 ENSEMBL cdna:SNAP chromosome:CEL140:III:13614377:13615559:-1 10/11 None
GENEFINDER00000008516 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:13614377:13615559:-1 10/11 None
T12D8.8.1 ENSEMBL cdna:known chromosome:CEL140:III:13614218:13621742:-1 gene:T12D8.8 11/11 A 
T12D8.8.2 ENSEMBL cdna:known chromosome:CEL140:III:13614218:13621751:-1 gene:T12D8.8 11/11 A 
T12D8.8.3 ENSEMBL cdna:known chromosome:CEL140:III:13614220:13621862:-1 gene:T12D8.8 11/11 A 
T12D8.8.4 ENSEMBL cdna:known chromosome:CEL140:III:13614227:13622005:-1 gene:T12D8.8 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
GENEFINDER00000041275 1/11 Cross Hyb Matching Probes None
SNAP00000041262 1/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:13614372-13621735(-) 100.0 100.0
Public Domain and Genome References
Gene Title TPR Domain (2 domains)
Ensembl T12D8.8
Entrez Gene 176794 Entrez gene
SwissProt O45786 EMBL-EBI
WormBase CE16405 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:13165_AT tetratricopeptide repeat (TPR)-containing protein at
ATH1-121501:254275_AT tetratricopeptide repeat (TPR)-containing protein at
CANINE_2:CFAAFFX.2582.1.S1_S_AT similar to heat shock 70kD protein binding protein cfa
CANINE_2:CFAAFFX.9633.1.S1_S_AT similar to heat shock 70kD protein binding protein cfa
CANINE_2:CFAAFFX.9633.1.S1_X_AT similar to heat shock 70kD protein binding protein cfa
CANINE:1589802_S_AT similar to heat shock 70kD protein binding protein cfa
CANINE:1591470_AT similar to heat shock 70kD protein binding protein cfa
CANINE:1587615_S_AT similar to heat shock 70kD protein binding protein cfa
CANINE_2:CFA.1050.3.S1_AT similar to heat shock 70kD protein binding protein cfa
DROSOPHILA_2:1623408_S_AT dm
DROSGENOME1:141203_AT dm
CHICKEN:GGA.7767.1.S1_S_AT suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) gga
CHICKEN:GGAAFFX.11887.1.S1_AT suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) gga
HG-U133_PLUS_2:207040_S_AT suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) hs
HG-U133A:207040_S_AT suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) hs
HG-U133A_2:207040_S_AT suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) hs
HG-U133_PLUS_2:208666_S_AT suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) hs
HG-U133A_2:208666_S_AT suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) hs
HG-FOCUS:208666_S_AT suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) hs
HG-U133A:208666_S_AT suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) hs
HG-U133_PLUS_2:208667_S_AT suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) hs
HG-U133A_2:208667_S_AT suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) hs
HG-U133A:208667_S_AT suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) hs
HG-U95AV2:1640_AT suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) hs
HC-G110:1640_AT suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) hs
HUGENEFL:U17714_AT suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) hs
U133_X3P:G4505562_3P_S_AT suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) hs
U133_X3P:G4049267_3P_A_AT suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) hs
U133_X3P:HS.119222.1.A2_3P_A_AT suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) hs
MG-U74AV2:97310_AT suppression of tumorigenicity 13 mm
MG-U74AV2:97309_AT suppression of tumorigenicity 13 mm
MOE430A:1460193_AT suppression of tumorigenicity 13 mm
MOUSE430A_2:1460193_AT suppression of tumorigenicity 13 mm
MOUSE430_2:1460193_AT suppression of tumorigenicity 13 mm
MOE430A:1416851_AT suppression of tumorigenicity 13 mm
MOUSE430A_2:1416851_AT suppression of tumorigenicity 13 mm
MOUSE430_2:1416851_AT suppression of tumorigenicity 13 mm
MG-U74BV2:111195_AT Suppression of tumorigenicity 13 (St13), mRNA mm
MG-U74BV2:112365_AT Suppression of tumorigenicity 13 (St13), mRNA mm
MOUSE430_2:1436113_A_AT Suppression of tumorigenicity 13 (St13), mRNA mm
MOE430B:1436113_A_AT Suppression of tumorigenicity 13 (St13), mRNA mm
MOE430B:1442775_AT Suppression of tumorigenicity 13 (St13), mRNA mm
MOUSE430_2:1442775_AT Suppression of tumorigenicity 13 (St13), mRNA mm
MU19KSUBB:TC31091_AT Suppression of tumorigenicity 13 (St13), mRNA mm
MU19KSUBC:TC37066_AT Suppression of tumorigenicity 13 (St13), mRNA mm
MU19KSUBC:TC39137_AT Suppression of tumorigenicity 13 (St13), mRNA mm
RN-U34:RC_AI171166_AT suppression of tumorigenicity 13 rn
RT-U34:RC_AI171166_AT suppression of tumorigenicity 13 rn
RG-U34A:RC_AI171166_AT suppression of tumorigenicity 13 rn
RN-U34:X82021CDS_AT suppression of tumorigenicity 13 rn
RT-U34:X82021CDS_AT suppression of tumorigenicity 13 rn
RG-U34A:X82021CDS_AT suppression of tumorigenicity 13 rn
RAE230A:1398848_AT suppression of tumorigenicity 13 rn
RAT230_2:1398848_AT suppression of tumorigenicity 13 rn
RAT230_2:1398409_AT Suppression of tumorigenicity 13 rn
RAE230A:1398409_AT Suppression of tumorigenicity 13 rn
RG-U34B:RC_AA955104_AT Suppression of tumorigenicity 13 rn
Protein Similarities
Method ID Description E-Value
blast CAB03349 Hypothetical protein T12D8.8 [Caenorhabditis elegans] emb|CAB05818.1| Hypothetical protein T12D8.8 [Caenorhabditis elegans] ref|NP_499811.1| T12D8.8 [Caenorhabditis elegans] 1.0E-153
blast CAE71350 Hypothetical protein CBG18253 [Caenorhabditis briggsae] 1.0E-125
Protein Domains
Database ID Description E-Value
Pfam IPR001440 EMBL-EBI TPR repeat 0.0016
Pfam IPR001440 EMBL-EBI TPR repeat 2.1E-8
Pfam IPR001440 EMBL-EBI TPR repeat 0.25
Sequence
Target Sequence 
>C. ELEGANS:190382_S_AT
aagccgccaacgagtggctcaaggaggtcgagccgaatgctcacaagatccaggagtaca
atcgggcagtcgaacgtcagaaggccgatatcgagctcgcggagcgtagagagcgggttc
gtcgtgctcaggaggctaataagaaggccgccgaggaggaagccaagcgtcaagccgaac
aaggagatgatttcgatttcgaaggaggattccccggtggaatgcccggaggtttccctg
gagccggtggaatgcctggaggatttcctggagcaccaggcggcggagccccaggaggaa
tgggcgctggaatcgaacaactgttcagtgatccggagatcgccgctgccattcaggatc
cggaagtgctgccagcgttgatggatatcatgcagaacccggcgaac

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAGCCGCCAACGAGTGGCTCAAGGA 270 147 659 Antisense
ATCCAGGAGTACAATCGGGCAGTCG 149 33 706 Antisense
GGGCAGTCGAACGTCAGAAGGCCGA 173 491 722 Antisense
AGAAGGCCGATATCGAGCTCGCGGA 372 75 737 Antisense
GGAGCGTAGAGAGCGGGTTCGTCGT 412 515 759 Antisense
GTTCGTCGTGCTCAGGAGGCTAATA 152 441 775 Antisense
GAGGAGGAAGCCAAGCGTCAAGCCG 494 403 811 Antisense
GCCTGGAGGATTTCCTGGAGCACCA 68 283 912 Antisense
TGGGCGCTGGAATCGAACAACTGTT 63 555 959 Antisense
GCTGCCATTCAGGATCCGGAAGTGC 514 293 1003 Antisense
GGATATCATGCAGAACCCGGCGAAC 467 509 1041 Antisense
Sequence Source Affymetrix Proprietary Database