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[190379_at] zinc metalloprotease

Description T12E12.6 /REP_DB=WormBase Gene ID /WP=CE13593 /TR=Q22433 /GB=AAB03123.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=zinc metalloprotease
Cluster 6grp_high1_10_10 > 70      4grp_high_8_8 > 46      6grp_total > 91      4grp_total > 49      6grp_high1_sub > 04      4grp_rule_based > L2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 217
1 2 3 4 range
A 45
(-3)
A 		262.3
(3)
P 		183.5
(0.8)
P 		113.1
(-1.1)
P 		217
B 64.4
(-3)
P 		217
(2.4)
P 		232.8
(3)
P 		64.4
(-3)
P 		168
C 72.5
(-3)
A 		236.9
(3)
P 		216.2
(2.2)
P 		152.6
(-0.1)
P 		164
avr 60.6
(-3) 		238.7
(3) 		210.8
(2.1) 		110
(-1.3) 		178

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 237
1 2 3 4 5 6 range
A 243.1
(2.1)
P 		154.3
(-0.4)
P 		149.7
(-0.5)
P 		276
(3)
P 		184.7
(0.5)
P 		59.5
(-3)
M 		217
B 194.7
(0.6)
P 		197
(0.6)
P 		109.6
(-1.8)
P 		282.9
(3)
P 		169.9
(-0.1)
P 		65.7
(-3)
P 		217
C 108.1
(-1)
P 		224.8
(2.8)
P 		152.4
(0.4)
P 		231.4
(3)
P 		132.2
(-0.2)
P 		46.4
(-3)
M 		185
avr 182
(0.6) 		192
(0.9) 		137.2
(-0.7) 		263.4
(3) 		162.3
(0.1) 		57.2
(-3) 		206
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 62
1 2 3 4 range
A 16.4
(-3)
A 		56.9
(3)
P 		48
(1.7)
P 		16.6
(-3)
P 		41
B 20.5
(-2)
P 		53.6
(3)
P 		53.9
(3)
P 		13.7
(-3)
P 		40
C 24
(-3)
A 		68.1
(2.1)
P 		75.4
(3)
P 		25.7
(-2.8)
P 		51
avr 20.3
(-2.8) 		59.5
(3) 		59.1
(2.9) 		18.7
(-3) 		41

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 60
1 2 3 4 5 6 range
A 44.8
(0.3)
P 		54.9
(1.4)
P 		32.6
(-1)
P 		70
(3)
P 		55.7
(1.5)
P 		14.5
(-3)
M 		56
B 67.7
(2.1)
P 		65.6
(1.9)
P 		26.6
(-2.8)
P 		74.9
(3)
P 		69
(2.3)
P 		24.5
(-3)
P 		50
C 40.1
(-0.2)
P 		68.6
(3)
P 		38.8
(-0.4)
P 		46.5
(0.5)
P 		42.8
(0.1)
P 		15.5
(-3)
M 		53
avr 50.9
(1.3) 		63
(2.9) 		32.7
(-1.1) 		63.8
(3) 		55.8
(1.9) 		18.2
(-3) 		46
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190379_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.10616
Sequence Type Exemplar sequence
Representative Public ID T12E12.6 NCBI
Target Description T12E12.6 /REP_DB=WormBase Gene ID /WP=CE13593 /TR=Q22433 /GB=AAB03123.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=zinc metalloprotease
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_068430(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_068430 NCBI Caenorhabditis elegans T12E12.6 (T12E12.6) mRNA, complete cds. 11/11 None
SNAP00000021920 ENSEMBL cdna:SNAP chromosome:CEL140:IV:5567170:5572988:-1 11/11 None
GENEFINDER00000021921 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:5564810:5572988:-1 11/11 None
T12E12.6 ENSEMBL cdna:known chromosome:CEL140:IV:5567032:5574096:-1 gene:T12E12.6 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:5567175-5573226(-) 100.0 100.0
Public Domain and Genome References
Gene Title zinc metalloprotease
Ensembl T12E12.6
Entrez Gene 188454 Entrez gene
WormBase CE37272 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4179 membrane alanyl aminopeptidase activity inferred from electronic annotation QuickGO AmiGO
8237 metallopeptidase activity inferred from electronic annotation QuickGO AmiGO
8270 zinc ion binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast NP_500831 T12E12.6 [Caenorhabditis elegans] 0.0
blast CAE72694 Hypothetical protein CBG19917 [Caenorhabditis briggsae] 0.0
blast T29564 hypothetical protein T12E12.6 - Caenorhabditis elegans 0.0
Protein Domains
Database ID Description E-Value
scop a.3.1.Two-domain cytochrome c All alpha proteins; Cytochrome c; Cytochrome c; Two-domain cytochrome c 0.209999993443489
Pfam IPR001930 EMBL-EBI Peptidase M1, membrane alanine aminopeptidase 1.6E-51
Pfam IPR001930 EMBL-EBI Peptidase M1, membrane alanine aminopeptidase 1.1E-38
Sequence
Target Sequence 
>C. ELEGANS:190379_AT
aacaatggaccatcatcacgtcttcaacaactctcacgacccctttggccattgaaaatg
acatcaactcttgcgattccacaattcgtattctcagagtccatagtttttgcatctgaa
aatgccccacttttggtgaatctcaatttcacttcatttatgagagttaactatgattca
ttgacatggacggctatttttaaatacatgttcgaagaaccagagttattctcagcagtt
ggccgagcccagttggtttcagatttttgttatttctacgcaaatgataaagttgacaat
ggaactattctcaaggaggccgttgtagatatggtgtactcgaaacctgaattcttcgaa
ctctgtgactggaatctttactggtgtcattctcgatccgatcaatcactttttgctcaa
gttgtacgtagtctggctctccgtttctcatctgcaacatttgaatccacatctgcattt
ggctgta

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AACAATGGACCATCATCACGTCTTC 114 135 1129 Antisense
CGACCCCTTTGGCCATTGAAAATGA 129 251 1165 Antisense
TGACATCAACTCTTGCGATTCCACA 529 571 1187 Antisense
AATGCCCCACTTTTGGTGAATCTCA 284 167 1249 Antisense
GTTATTCTCAGCAGTTGGCCGAGCC 107 447 1353 Antisense
GCCGAGCCCAGTTGGTTTCAGATTT 302 283 1370 Antisense
GAATTCTTCGAACTCTGTGACTGGA 124 325 1477 Antisense
TTACTGGTGTCATTCTCGATCCGAT 458 683 1506 Antisense
TCAAGTTGTACGTAGTCTGGCTCTC 163 633 1545 Antisense
TCCGTTTCTCATCTGCAACATTTGA 397 595 1568 Antisense
GAATCCACATCTGCATTTGGCTGTA 111 331 1591 Antisense
Sequence Source Affymetrix Proprietary Database